Hagiwara-Nagasawa M, Kambayashi R, Goto A, Nunoi Y, Izumi-Nakaseko H, Chiba K, Wada T, Takei Y, Matsumoto A, Sugiyama A (2021)
Analysis of electropharmacological and proarrhythmic effects of donepezil using the halothane-anesthetized intact dogs and the conscious chronic atrioventricular block ones
Naunyn Schmiedebergs Arch Pharmacol 394: 581

Ishizaki Y, Furihata T, Oyama Y, Ohura K, Imai T, Hosokawa M, Akita H, Chiba K (2018)
Development of a Caco-2 Cell Line Carrying the Human Intestine-Type CES Expression Profile as a Promising Tool for Ester-Containing Drug Permeability Studies
Biol Pharm Bull 41: 697

Yoshii K, Yamaguchi T, Hirayama M, Toda R, Kinomoto T, Kawabata Y, Chiba K (2016)
Distribution of acotiamide, an orally active acetylcholinesterase inhibitor, into the myenteric plexus of rat and dog stomachs
Life Sciences 145: 93

Hori T, Jin L, Fujii A, Furihata T, Nagahara Y, Chiba K, Hosokawa M (2012)
Dexamethasone-mediated transcriptional regulation of rat carboxylesterase 2 gene
Xenobiotica 42: 614

Hosokawa M, Furihata T, Yaginuma Y, Yamamoto N, Watanabe N, Tsukada E, Ohhata Y, Kobayashi K, Satoh T, Chiba K (2008)
Structural organization and characterization of the regulatory element of the human carboxylesterase (CES1A1 and CES1A2) genes
Drug Metab Pharmacokinet 23: 73

Hosokawa M, Furihata T, Yaginuma Y, Yamamoto N, Koyano N, Fujii A, Nagahara Y, Satoh T, Chiba K (2007)
Genomic structure and transcriptional regulation of the rat, mouse, and human carboxylesterase genes
Drug Metabolism Reviews 39: 1

Furihata T, Hosokawa M, Masuda M, Satoh T, Chiba K (2006)
Hepatocyte nuclear factor-4alpha plays pivotal roles in the regulation of mouse carboxylesterase 2 gene transcription in mouse liver
Archives of Biochemistry & Biophysics 447: 107

Imai T, Taketani M, Shii M, Hosokawa M, Chiba K (2006)
Substrate specificity of carboxylesterase isozymes and their contribution to hydrolase activity in human liver and small intestine
Drug Metabolism & Disposition: The Biological Fate of Chemicals 34: 1734

Furihata T, Hosokawa M, Fujii A, Derbel M, Satoh T, Chiba K (2005)
Dexamethasone-induced methylprednisolone hemisuccinate hydrolase: its identification as a member of the rat carboxylesterase 2 family and its unique existence in plasma
Biochemical Pharmacology 69: 1287

Furihata T, Hosokawa M, Koyano N, Nakamura T, Satoh T, Chiba K (2004)
Identification of di-(2-ethylhexyl) phthalate-induced carboxylesterase 1 in C57BL/6 mouse liver microsomes: purification, cDNA cloning, and baculovirus-mediated expression
Drug Metabolism & Disposition: The Biological Fate of Chemicals 32: 1170

Furihata T, Hosokawa M, Nakata F, Satoh T, Chiba K (2003)
Purification, molecular cloning, and functional expression of inducible liver acylcarnitine hydrolase in C57BL/6 mouse, belonging to the carboxylesterase multigene family
Archives of Biochemistry & Biophysics 416: 101

Hosokawa M, Suzuki K, Takahashi D, Mori M, Satoh T, Chiba K (2001)
Purification, molecular cloning, and functional expression of dog liver microsomal acyl-CoA hydrolase: a member of the carboxylesterase multigene family
Archives of Biochemistry & Biophysics 389: 245

Kudo S, Umehara K, Hosokawa M, Miyamoto G, Chiba K, Satoh T (2000)
Phenacetin deacetylase activity in human liver microsomes: distribution, kinetics, and chemical inhibition and stimulation
Journal of Pharmacology & Experimental Therapeutics 294: 80

Mori M, Hosokawa M, Ogasawara Y, Tsukada E, Chiba K (1999)
cDNA cloning, characterization and stable expression of novel human brain carboxylesterase
FEBS Letters 458: 17

Takayama H, Watanabe A, Hosokawa M, Chiba K, Satoh T, Aimi N (1998)
Synthesis of a new class of camptothecin derivatives, the long-chain fatty acid esters of 10-hydroxycamptothecin, as a potent prodrug candidate, and their in vitro metabolic conversion by carboxylesterases
Bioorganic & Medicinal Chemistry Lett 8: 415

Kobayashi H, Yuyama A, Chiba K (1986)
Cholinergic system of brain tissue in rats poisoned with the organophosphate, 0,0-dimethyl 0-(2,2-dichlorovinyl) phosphate
Toxicol Appl Pharmacol 82: 32