Costa LG, Garrick JM, Roque PJ, Pellacani C (2016)
Mechanisms of Neuroprotection by Quercetin: Counteracting Oxidative Stress and More
Oxid Med Cell Longev 2016: 2986796

Furlong CE, Marsillach J, Jarvik GP, Costa LG (2016)
Paraoxonases-1, -2 and -3: What are their functions?
Chemico-Biological Interactions 259: 51

Garrick JM, Dao K, de Laat R, Elsworth J, Cole TB, Marsillach J, Furlong CE, Costa LG (2016)
Developmental expression of paraoxonase 2
Chemico-Biological Interactions 259: 168

Roque PJ, Dao K, Costa LG (2016)
Microglia mediate diesel exhaust particle-induced cerebellar neuronal toxicity through neuroinflammatory mechanisms
Neurotoxicology 56: 204

Cole TB, Li WF, Co AL, Hay AM, MacDonald JW, Bammler TK, Farin FM, Costa LG, Furlong CE (2014)
Repeated Gestational Exposure of Mice to Chlorpyrifos Oxon Is Associated with Paraoxonase 1 (PON1) Modulated Effects in Maternal and Fetal Tissues
Toxicol Sci 141: 409

Costa LG, de Laat R, Dao K, Pellacani C, Cole TB, Furlong CE (2014)
Paraoxonase-2 (PON2) in brain and its potential role in neuroprotection
Neurotoxicology 43: 3

Pizzurro DM, Dao K, Costa LG (2014)
Diazinon and diazoxon impair the ability of astrocytes to foster neurite outgrowth in primary hippocampal neurons
Toxicol Appl Pharmacol 274: 372

Pizzurro DM, Dao K, Costa LG (2014)
Astrocytes protect against diazinon- and diazoxon-induced inhibition of neurite outgrowth by regulating neuronal glutathione
Toxicology 318: 59

Costa LG, Giordano G, Cole TB, Marsillach J, Furlong CE (2013)
Paraoxonase 1 (PON1) as a genetic determinant of susceptibility to organophosphate toxicity
Toxicology 307: 115

Costa LG, Tait L, de Laat R, Dao K, Giordano G, Pellacani C, Cole TB, Furlong CE (2013)
Modulation of Paraoxonase 2 (PON2) in Mouse Brain by the Polyphenol Quercetin: A Mechanism of Neuroprotection?
Neurochem Res 38: 1809

Giordano G, Tait L, Furlong CE, Cole TB, Kavanagh TJ, Costa LG (2013)
Gender differences in brain susceptibility to oxidative stress are mediated by levels of paraoxonase-2 expression
Free Radic Biol Med 58: 98

Marsillach J, Costa LG, Furlong CE (2013)
Protein adducts as biomarkers of exposure to organophosphorus compounds
Toxicology 307: 46

Cole TB, Fisher JC, Burbacher TM, Costa LG, Furlong CE (2012)
Neurobehavioral assessment of mice following repeated postnatal exposure to chlorpyrifos-oxon
Neurotoxicology & Teratology 34: 311

Camps J, Joven J, Mackness B, Mackness MI, Tawfik DS, Draganov DI, Costa LG, Paragh G, Seres I, Horke S, James RW, Hernandez AF, Reddy ST, Shih DM, Navab M, Rochu D, Aviram M (2011)
Paraoxonase-1 and clopidogrel efficacy
Nat Med 17: 1041

Cole TB, Beyer RP, Bammler TK, Park SS, Farin FM, Costa LG, Furlong CE (2011)
Repeated developmental exposure of mice to chlorpyrifos oxon is associated with paraoxonase 1 (PON1)-modulated effects on cerebellar gene expression
Toxicol Sci 123: 155

Costa LG, Giordano G, Furlong CE (2011)
Pharmacological and dietary modulators of paraoxonase 1 (PON1) activity and expression: the hunt goes on
Biochemical Pharmacology 81: 337

Giordano G, Cole TB, Furlong CE, Costa LG (2011)
Paraoxonase 2 (PON2) in the mouse central nervous system: a neuroprotective role?
Toxicol Appl Pharmacol 256: 369

Cole TB, Jansen K, Park S, Li WF, Furlong CE, Costa LG (2010)
The toxicity of mixtures of specific organophosphate compounds is modulated by paraoxonase 1 status
Advances in Experimental Medicine & Biology 660: 47

Furlong CE, Suzuki SM, Stevens RC, Marsillach J, Richter RJ, Jarvik GP, Checkoway H, Samii A, Costa LG, Griffith A, Roberts JW, Yearout D, Zabetian CP (2010)
Human PON1, a biomarker of risk of disease and exposure
Chemico-Biological Interactions 187: 355

Jansen KL, Cole TB, Park SS, Furlong CE, Costa LG (2009)
Paraoxonase 1 (PON1) modulates the toxicity of mixed organophosphorus compounds
Toxicol Appl Pharmacol 236: 142

Eaton DL, Daroff RB, Autrup H, Bridges J, Buffler P, Costa LG, Coyle J, McKhann G, Mobley WC, Nadel L, Neubert D, Schulte-Hermann R, Spencer PS (2008)
Review of the toxicology of chlorpyrifos with an emphasis on human exposure and neurodevelopment
Crit Rev Toxicol 38 Suppl 2: 1

Costa LG (2006)
Current issues in organophosphate toxicology
Clinica Chimica Acta 366: 1

Cole TB, Walter BJ, Shih DM, Tward AD, Lusis AJ, Timchalk C, Richter RJ, Costa LG, Furlong CE (2005)
Toxicity of chlorpyrifos and chlorpyrifos oxon in a transgenic mouse model of the human paraoxonase (PON1) Q192R polymorphism
Pharmacogenet Genomics 15: 589

Costa LG, Cole TB, Furlong CE (2005)
Paraoxonase (PON1): from toxicology to cardiovascular medicine
Acta Biomed 76 Suppl 2: 50

Costa LG, Cole TB, Vitalone A, Furlong CE (2005)
Measurement of paraoxonase (PON1) status as a potential biomarker of susceptibility to organophosphate toxicity
Clinica Chimica Acta 352: 37

Costa LG, Vitalone A, Cole TB, Furlong CE (2005)
Modulation of paraoxonase (PON1) activity
Biochemical Pharmacology 69: 541

Furlong CE, Cole TB, Walter BJ, Shih DM, Tward A, Lusis AJ, Timchalk C, Richter RJ, Costa LG (2005)
Paraoxonase 1 (PON1) status and risk of insecticide exposure
J Biochem Mol Toxicol 19: 182

Furlong CE, Cole TB, Jarvik GP, Pettan-Brewer C, Geiss GK, Richter RJ, Shih DM, Tward AD, Lusis AJ, Costa LG (2005)
Role of paraoxonase (PON1) status in pesticide sensitivity: genetic and temporal determinants
Neurotoxicology 26: 651

Zurich MG, Honegger P, Schilter B, Costa LG, Monnet-Tschudi F (2004)
Involvement of glial cells in the neurotoxicity of parathion and chlorpyrifos
Toxicol Appl Pharmacol 201: 97

Furlong CE, Li WF, Richter RJ, Shih DM, Lusis AJ, Alleva E, Costa LG (2000)
Genetic and temporal determinants of pesticide sensitivity: role of paraoxonase (PON1)
Neurotoxicology 21: 91

Li WF, Costa LG, Richter RJ, Hagen T, Shih DM, Tward A, Lusis AJ, Furlong CE (2000)
Catalytic efficiency determines the in-vivo efficacy of PON1 for detoxifying organophosphorus compounds
Pharmacogenetics 10: 767

Monnet-Tschudi F, Zurich MG, Schilter B, Costa LG, Honegger P (2000)
Maturation-dependent effects of chlorpyrifos and parathion and their oxygen analogs on acetylcholinesterase and neuronal and glial markers in aggregating brain cell cultures
Toxicol Appl Pharmacol 165: 175

Costa LG, Li WF, Richter RJ, Shih DM, Lusis A, Furlong CE (1999)
The role of paraoxonase (PON1) in the detoxication of organophosphates and its human polymorphism
Chemico-Biological Interactions 119-120: 429

Castoldi AF, Barni S, Randine G, Costa LG, Manzo L (1998)
Ethanol selectively interferes with the trophic action of NMDA and carbachol on cultured cerebellar granule neurons undergoing apoptosis
Brain Research Developmental Brain Research 111: 279

Furlong CE, Li WF, Costa LG, Richter RJ, Shih DM, Lusis AJ (1998)
Genetically determined susceptibility to organophosphorus insecticides and nerve agents: developing a mouse model for the human PON1 polymorphism
Neurotoxicology 19: 645

Shih DM, Gu L, Xia YR, Navab M, Li WF, Hama S, Castellani LW, Furlong CE, Costa LG, Fogelman AM, Lusis AJ (1998)
Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis
Nature 394: 284

Li WF, Matthews C, Disteche CM, Costa LG, Furlong CE (1997)
Paraoxonase (PON1) gene in mice: sequencing, chromosomal localization and developmental expression
Pharmacogenetics 7: 137

Castoldi AF, Candura SM, Costa Paola, Manzo L, Costa LG (1996)
Interaction of mercury compounds with muscarinic receptor subtypes in the rat brain
Neurotoxicology 17: 735

Guizzetti M, Costa Paola, Peters J, Costa LG (1996)
Acetylcholine as a mitogen: muscarinic receptor-mediated proliferation of rat astrocytes and human astrocytoma cells
European Journal of Pharmacology 297: 265

Yagle K, Costa LG (1996)
Effects of organophosphate exposure on muscarinic acetylcholine receptor subtype mRNA levels in the adult rat
Neurotoxicology 17: 523

Costa Paola, Traver DJ, Auger CB, Costa LG (1995)
Poster: Identification of m3, m4, m5 subtypes of muscarinic receptor mRNA in human blood mononuclear cells
Life Sciences 56(11-12): 1019

Costa LG, Guizzetti M (1995)
Poster: Activation of muscarinic receptors induces proliferation of rat cortical astrocytes and human astrocytoma cells: Role of protein kinase C
Life Sciences 56(11-12): 1026

Costa Paola, Auger CB, Traver DJ, Costa LG (1995)
Identification of m3, m4 and m5 subtypes of muscarinic receptor mRNA in human blood mononuclear cells
Journal of Neuroimmunology 60: 45

Li WF, Furlong CE, Costa LG (1995)
Paraoxonase protects against chlorpyrifos toxicity in mice
Toxicology Letters 76: 219

Costa Paola, Castoldi AF, Traver DJ, Costa LG (1994)
Lack of m2 muscarinic acetylcholine receptor mRNA in rat lymphocytes
Journal of Neuroimmunology 49: 115

Costa Paola, Traver DJ, Auger CB, Costa LG (1994)
Expression of cholinergic muscarinic receptor subtypes mRNA in rat blood mononuclear cells
Immunopharmacology 28: 113

Ehrich M, Intropido L, Costa LG (1994)
Interaction of organophosphorus compounds with muscarinic receptors in SH-SY5Y human neuroblastoma cells
J Toxicol Environ Health 43: 51

Castoldi AF, Manzo L, Costa LG (1993)
Cyclic GMP formation induced by muscarinic receptors is mediated by nitric oxide synthesis in rat cortical primary cultures
Brain Research 610: 57

Fitzgerald BB, Costa LG (1993)
Modulation of muscarinic receptors and acetylcholinesterase activity in lymphocytes and in brain areas following repeated organophosphate exposure in rats
Fundamental & Applied Toxicology 20: 210

Furlong CE, Costa LG, Hassett C, Richter RJ, Sundstrom JA, Adler DA, Disteche CM, Omiecinski CJ, Chapline C, Crabb JW, et al. (1993)
Human and rabbit paraoxonases: purification, cloning, sequencing, mapping and role of polymorphism in organophosphate detoxification
Chemico-Biological Interactions 87: 35

Li WF, Costa LG, Furlong CE (1993)
Serum paraoxonase status: a major factor in determining resistance to organophosphates
Journal of Toxicology & Environmental Health 40: 337

Tan XX, Castoldi AF, Manzo L, Costa LG (1993)
Interaction of ethanol with muscarinic receptor-stimulated phosphoinositide metabolism during the brain growth spurt in the rat: role of acetaldehyde
Neuroscience Letters 156: 13

Tang C, Castoldi AF, Costa LG (1993)
Effects of the muscarinic agonist oxotremorine on membrane fluidity in rat lymphocytes
Biochemistry & Molecular Biology International 29: 1047

Candura SM, Castoldi AF, Manzo L, Costa LG (1991)
Interaction of aluminum ions with phosphoinositide metabolism in rat cerebral cortical membranes
Life Sciences 49: 1245

Castoldi AF, Fitzgerald B, Manzo L, Tonini M, Costa LG (1991)
Muscarinic M2 receptors in rat brain labeled with [3H] AF-DX 384
Res Commun Chem Pathol Pharmacol 74: 371

Costa LG, McDonald BE, Murphy SD, Omenn GS, Richter RJ, Motulsky AG, Furlong CE (1990)
Serum paraoxonase and its influence on paraoxon and chlorpyrifos-oxon toxicity in rats
Toxicol Appl Pharmacol 103: 66

McDonald BE, Costa LG, Murphy SD (1988)
Spatial memory impairment and central muscarinic receptor loss following prolonged treatment with organophosphates
Toxicol Lett 40: 42