Hayes TR, Chao CK, Blecha JE, Huynh TL, VanBrocklin HF, Zinn KR, Gerdes JM, Thompson CM (2023)
[(11)C]Paraoxon: Radiosynthesis, Biodistribution and In Vivo Positron Emission Tomography (PET) Imaging in Rat
Journal of Pharmacology & Experimental Therapeutics

Hayes TR, Chao CK, Blecha JE, Huynh TL, Zinn KR, Thompson CM, Gerdes JM, VanBrocklin HF (2021)
Biological Distribution and Metabolic Profiles of Carbon-11 and Fluorine-18 Tracers of VX- and Sarin-Analogs in Sprague-Dawley Rats
Chemical Research in Toxicology 34: 63

Hayes TR, Blecha JE, Chao CK, Huynh TL, VanBrocklin HD, Zinn KR, Taylor P, Gerdes JM, Thompson CM (2020)
Positron emission tomography evaluation of oxime countermeasures in live rats using the tracer O-(2-[(18) F]fluoroethyl)-O-(p-nitrophenyl)methylphosphonate [(18) F]-VXS
Annals of the New York Academy of Sciences

Thompson CM, Gerdes JM, VanBrocklin HF (2020)
Positron emission tomography studies of organophosphate chemical threats and oxime countermeasures
Neurobiol Dis 133: 104455

Hayes TR, Blecha JE, Thompson CM, Gerdes JM, VanBrocklin HF (2019)
Divergent synthesis of organophosphate [(11)C]VX- and [(11)C]Sarin-surrogates from a common set of starting materials
Appl Radiat Isot 151: 182

Chao CK, Balasubramanian N, Gerdes JM, Thompson CM (2018)
The inhibition, reactivation and mechanism of VX-, sarin-, fluoro-VX and fluoro-sarin surrogates following their interaction with HuAChE and HuBuChE
Chemico-Biological Interactions 291: 220

Hayes TR, Thompson CM, Blecha JE, Gerdes JM, VanBrocklin HF (2018)
Radiosynthesis of O-(1-[(18) F]fluoropropan-2-yl)-O-(4-nitrophenyl)methylphosphonate: A novel PET tracer surrogate of sarin
J Labelled Comp Radiopharm 61: 1089

Neumann KD, Blecha JE, Hayes TR, Huynh T, Chao CK, Guilloteau N, Zinn KR, VanBrocklin HF, Thompson CM, Gerdes JM (2018)
Radiosynthesis, ex Vivo Biodistribution, and in Vivo Positron Emission Tomography Imaging Evaluations of [(11)C]2-Pyridinealdoxime Methiodide ([(11)C]2-PAM): A First-In-Class Antidote Tracer for Organophosphate Intoxication
ACS Chem Neurosci 9: 3007

Neumann KD, Thompson CM, Blecha JE, Gerdes JM, VanBrocklin HF (2017)
An improved radiosynthesis of O-(2-[18 F]fluoroethyl)-O-(p-nitrophenyl)methylphosphonate: A first-in-class cholinesterase PET tracer
J Labelled Comp Radiopharm 60: 337

Chao CK, Ahmed SK, Gerdes JM, Thompson CM (2016)
Novel Organophosphate Ligand O-(2-Fluoroethyl)-O-(p-Nitrophenyl)Methylphosphonate: Synthesis, Hydrolytic Stability and Analysis of the Inhibition and Reactivation of Cholinesterases
Chemical Research in Toxicology 29: 1810

James SL, Ahmed SK, Murphy S, Braden MR, Belabassi Y, VanBrocklin HF, Thompson CM, Gerdes JM (2014)
A Novel Fluorine-18 beta-Fluoroethoxy Organophosphate Positron Emission Tomography Imaging Tracer Targeted to Central Nervous System Acetylcholinesterase
ACS Chem Neurosci 5: 519

Kaleem Ahmed S, Belabassi Y, Sankaranarayanan L, Chao CK, Gerdes JM, Thompson CM (2013)
Synthesis and anti-acetylcholinesterase properties of novel beta- and gamma-substituted alkoxy organophosphonates
Bioorganic & Medicinal Chemistry Lett 23: 2048

Guo L, Suarez AI, Braden MR, Gerdes JM, Thompson CM (2010)
Inhibition of acetylcholinesterase by chromophore-linked fluorophosphonates
Bioorganic & Medicinal Chemistry Lett 20: 1194