Mashimo M, Kawashima K, Fujii T (2022)
Non-neuronal Cholinergic Muscarinic Acetylcholine Receptors in the Regulation of Immune Function
Biol Pharm Bull 45: 675
Yamahashi Y, Lin YH, Mouri A, Iwanaga S, Kawashima K, Tokumoto Y, Watanabe Y, Faruk MO, Zhang X, Tsuboi D, Nakano T, Saito N, Nagai T, Yamada K, Kaibuchi K (2022)
Phosphoproteomic of the acetylcholine pathway enables discovery of the PKC-beta-PIX-Rac1-PAK cascade as a stimulatory signal for aversive learning
Mol Psychiatry
Mashimo M, Moriwaki Y, Misawa H, Kawashima K, Fujii T (2021)
Regulation of Immune Functions by Non-Neuronal Acetylcholine (ACh) via Muscarinic and Nicotinic ACh Receptors
Int J Mol Sci 22:
Fujii T, Mashimo M, Moriwaki Y, Misawa H, Ono S, Horiguchi K, Kawashima K (2017)
Physiological functions of the cholinergic system in immune cells
J Pharmacol Sci 134: 1
Fujii T, Mashimo M, Moriwaki Y, Misawa H, Ono S, Horiguchi K, Kawashima K (2017)
Expression and Function of the Cholinergic System in Immune Cells
Front Immunol 8: 1085
Grando SA, Kawashima K, Kirkpatrick CJ, Kummer W, Wessler I (2015)
Recent progress in revealing the biological and medical significance of the non-neuronal cholinergic system
Int Immunopharmacol 29: 1
Kawashima K, Fujii T, Moriwaki Y, Misawa H, Horiguchi K (2015)
Non-neuronal cholinergic system in regulation of immune function with a focus on alpha7 nAChRs
Int Immunopharmacol 29: 127
Moriwaki Y, Takada K, Tsuji S, Kawashima K, Misawa H (2015)
Transcriptional regulation of SLURP2, a psoriasis-associated gene, is under control of IL-22 in the skin: A special reference to the nested gene LYNX1
Int Immunopharmacol 29: 71
Fujii T, Horiguchi K, Sunaga H, Moriwaki Y, Misawa H, Kasahara T, Tsuji S, Kawashima K (2014)
SLURP-1, an endogenous alpha7 nicotinic acetylcholine receptor allosteric ligand, is expressed in CD205(+) dendritic cells in human tonsils and potentiates lymphocytic cholinergic activity
Journal of Neuroimmunology 267: 43
Kishi T, Fukuo Y, Okochi T, Kawashima K, Moriwaki M, Furukawa O, Musso GM, Fujita K, Correll CU, Iwata N (2013)
Relationship between nicotine dependence and the endophenotype-related trait of cognitive function but not acoustic startle reponses in Japanese patients with schizophrenia
Hum Psychopharmacol 28: 220
Narumoto O, Niikura Y, Ishii S, Morihara H, Okashiro S, Nakahari T, Nakano T, Matsumura H, Shimamoto C, Moriwaki Y, Misawa H, Yamashita N, Nagase T, Kawashima K (2013)
Effect of secreted lymphocyte antigen-6/urokinase-type plasminogen activator receptor-related peptide-1 (SLURP-1) on airway epithelial cells
Biochemical & Biophysical Research Communications 438: 175
Uchida S, Hotta H, Misawa H, Kawashima K (2013)
The missing link between long-term stimulation of nicotinic receptors and the increases of acetylcholine release and vasodilation in the cerebral cortex of aged rats
J Physiol Sci 63: 95
Fujii T, Takada-Takatori Y, Kawashima K (2012)
Regulatory mechanisms of acetylcholine synthesis and release by T cells
Life Sciences 91: 981
Fujii T, Takada-Takatori Y, Horiguchi K, Kawashima K (2012)
Mediatophore regulates acetylcholine release from T cells
Journal of Neuroimmunology 244: 16
Grando SA, Kawashima K, Kirkpatrick CJ, Meurs H, Wessler I (2012)
The non-neuronal cholinergic system: basic science, therapeutic implications and new perspectives
Life Sciences 91: 969
Kawashima K, Fujii T, Moriwaki Y, Misawa H (2012)
Critical roles of acetylcholine and the muscarinic and nicotinic acetylcholine receptors in the regulation of immune function
Life Sciences 91: 1027
Kawashima K, Fujii T, Moriwaki Y, Misawa H, Horiguchi K (2012)
Reconciling neuronally and nonneuronally derived acetylcholine in the regulation of immune function
Annals of the New York Academy of Sciences 1261: 7
Matsumoto H, Shibasaki K, Uchigashima M, Koizumi A, Kurachi M, Moriwaki Y, Misawa H, Kawashima K, Watanabe M, Kishi S, Ishizaki Y (2012)
Localization of acetylcholine-related molecules in the retina: implication of the communication from photoreceptor to retinal pigment epithelium
PLoS ONE 7: e42841
Uchida S, Hotta H, Misawa H, Kawashima K (2011)
Sustained subcutaneous infusion of nicotine enhances cholinergic vasodilation in the cerebral cortex induced by stimulation of the nucleus basalis of Meynert in rats
European Journal of Pharmacology 654: 235
Kaneko T, Minamisawa K, Isawa T, Nakatsukasa H, Mitsui H, Kawaharada Y, Nakamura Y, Watanabe A, Kawashima K, Ono A, Shimizu Y, Takahashi C, Minami C, Fujishiro T, Kohara M, Katoh M, Nakazaki N, Nakayama S, Yamada M, Tabata S, Sato S (2010)
Complete genomic structure of the cultivated rice endophyte Azospirillum sp. B510
DNA Research 17: 37
Narumoto O, Horiguchi K, Horiguchi S, Moriwaki Y, Takano-Ohmuro H, Shoji S, Misawa H, Yamashita N, Nagase T, Kawashima K (2010)
Down-regulation of secreted lymphocyte antigen-6/urokinase-type plasminogen activator receptor-related peptide-1 (SLURP-1), an endogenous allosteric alpha7 nicotinic acetylcholine receptor modulator, in murine and human asthmatic conditions
Biochemical & Biophysical Research Communications 398: 713
Fujii T, Masai M, Misawa H, Okuda T, Takada-Takatori Y, Moriwaki Y, Haga T, Kawashima K (2009)
Acetylcholine synthesis and release in NIH3T3 cells coexpressing the high-affinity choline transporter and choline acetyltransferase
Journal of Neuroscience Research 87: 3024
Horiguchi K, Horiguchi S, Yamashita N, Irie K, Masuda J, Takano-Ohmuro H, Himi T, Miyazawa M, Moriwaki Y, Okuda T, Misawa H, Ozaki H, Kawashima K (2009)
Expression of SLURP-1, an endogenous alpha7 nicotinic acetylcholine receptor allosteric ligand, in murine bronchial epithelial cells
Journal of Neuroscience Research 87: 2740
Moriwaki Y, Watanabe Y, Shinagawa T, Kai M, Miyazawa M, Okuda T, Kawashima K, Yabashi A, Waguri S, Misawa H (2009)
Primary sensory neuronal expression of SLURP-1, an endogenous nicotinic acetylcholine receptor ligand
Neurosci Res 64: 403
Uchida S, Hotta H, Kawashima K (2009)
Long-term nicotine treatment reduces cerebral cortical vasodilation mediated by alpha4beta2-like nicotinic acetylcholine receptors in rats
European Journal of Pharmacology 609: 100
Fujii T, Takada-Takatori Y, Kawashima K (2008)
Basic and clinical aspects of non-neuronal acetylcholine: expression of an independent, non-neuronal cholinergic system in lymphocytes and its clinical significance in immunotherapy
J Pharmacol Sci 106: 186
Kawashima K, Fujii T (2008)
Basic and clinical aspects of non-neuronal acetylcholine: overview of non-neuronal cholinergic systems and their biological significance
J Pharmacol Sci 106: 167
Kishi T, Ikeda M, Kitajima T, Yamanouchi Y, Kinoshita Y, Kawashima K, Inada T, Harano M, Komiyama T, Hori T, Yamada M, Iyo M, Sora I, Sekine Y, Ozaki N, Ujike H, Iwata N (2008)
Alpha4 and beta2 subunits of neuronal nicotinic acetylcholine receptor genes are not associated with methamphetamine-use disorder in the Japanese population
Annals of the New York Academy of Sciences 1139: 70
Kishi T, Ikeda M, Kitajima T, Yamanouchi Y, Kinoshita Y, Kawashima K, Okochi T, Inada T, Ozaki N, Iwata N (2008)
Genetic association analysis of tagging SNPs in alpha4 and beta2 subunits of neuronal nicotinic acetylcholine receptor genes (CHRNA4 and CHRNB2) with schizophrenia in the Japanese population
J Neural Transm 115: 1457
Misawa H, Fujigaya H, Nishimura T, Moriwaki Y, Okuda T, Kawashima K, Nakata K, Ruggiero AM, Blakely RD, Nakatsu F, Ohno H (2008)
Aberrant trafficking of the high-affinity choline transporter in AP-3-deficient mice
European Journal of Neuroscience 27: 3109
Fujii T, Takada-Takatori Y, Kawashima K (2007)
Roles played by lymphocyte function-associated antigen-1 in the regulation of lymphocytic cholinergic activity
Life Sciences 80: 2320
Fujii YX, Fujigaya H, Moriwaki Y, Misawa H, Kasahara T, Grando SA, Kawashima K (2007)
Enhanced serum antigen-specific IgG1 and proinflammatory cytokine production in nicotinic acetylcholine receptor alpha7 subunit gene knockout mice
Journal of Neuroimmunology 189: 69
Fujii YX, Tashiro A, Arimoto K, Fujigaya H, Moriwaki Y, Misawa H, Fujii T, Matsui M, Kasahara T, Kawashima K (2007)
Diminished antigen-specific IgG1 and interleukin-6 production and acetylcholinesterase expression in combined M1 and M5 muscarinic acetylcholine receptor knockout mice
Journal of Neuroimmunology 188: 80
Grando SA, Kawashima K, Kirkpatrick CJ, Wessler I (2007)
Recent progress in understanding the non-neuronal cholinergic system in humans
Life Sciences 80: 2181
Kaneko T, Nakajima N, Okamoto S, Suzuki I, Tanabe Y, Tamaoki M, Nakamura Y, Kasai F, Watanabe A, Kawashima K, Kishida Y, Ono A, Shimizu Y, Takahashi C, Minami C, Fujishiro T, Kohara M, Katoh M, Nakazaki N, Nakayama S, Yamada M, Tabata S, Watanabe MM (2007)
Complete genomic structure of the bloom-forming toxic cyanobacterium Microcystis aeruginosa NIES-843
DNA Research 14: 247
Kawashima K, Misawa H, Moriwaki Y, Fujii YX, Fujii T, Horiuchi Y, Yamada T, Imanaka T, Kamekura M (2007)
Ubiquitous expression of acetylcholine and its biological functions in life forms without nervous systems
Life Sciences 80: 2206
Kawashima K, Yoshikawa K, Fujii YX, Moriwaki Y, Misawa H (2007)
Expression and function of genes encoding cholinergic components in murine immune cells
Life Sciences 80: 2314
Kurzen H, Wessler I, Kirkpatrick CJ, Kawashima K, Grando SA (2007)
The non-neuronal cholinergic system of human skin
Hormone & Metabolic Research 39: 125
Moriwaki Y, Yoshikawa K, Fukuda H, Fujii YX, Misawa H, Kawashima K (2007)
Immune system expression of SLURP-1 and SLURP-2, two endogenous nicotinic acetylcholine receptor ligands
Life Sciences 80: 2365
Fujii T, Masuyama K, Kawashima K (2006)
Simvastatin regulates non-neuronal cholinergic activity in T lymphocytes via CD11a-mediated pathways
Journal of Neuroimmunology 179: 101
Kawashima K (2006)
[Expression of non-neuronal acetylcholine and its biological roles in mammalian species]
Nihon Yakurigaku Zasshi 127: 368
Yamada T, Fujii T, Kanai T, Amo T, Imanaka T, Nishimasu H, Wakagi T, Shoun H, Kamekura M, Kamagata Y, Kato T, Kawashima K (2005)
Expression of acetylcholine (ACh) and ACh-synthesizing activity in Archaea
Life Sciences 77: 1935
Kawashima K, Fujii T (2004)
Expression of non-neuronal acetylcholine in lymphocytes and its contribution to the regulation of immune function
Front Biosci 9: 2063
Suenaga A, Fujii T, Ogawa H, Maruyama T, Ohuchida S, Katsube N, Obata T, Kawashima K (2004)
Up-regulation of lymphocytic cholinergic activity by ONO-4819, a selective prostaglandin EP4 receptor agonist, in MOLT-3 human leukemic T cells
Vascul Pharmacol 41: 51
Suzuki T, Takagi R, Kawashima K (2004)
Picrotoxin increased acetylcholine release from rat cultured embryonic septal neurons
Neuroscience Letters 356: 57
Fujii T, Okuda T, Haga T, Kawashima K (2003)
Detection of the high-affinity choline transporter in the MOLT-3 human leukemic T-cell line
Life Sciences 72: 2131
Fujii T, Watanabe Y, Inoue T, Kawashima K (2003)
Upregulation of mRNA encoding the M5 muscarinic acetylcholine receptor in human T- and B-lymphocytes during immunological responses
Neurochem Res 28: 423
Grando SA, Kawashima K, Wessler I (2003)
Introduction: the non-neuronal cholinergic system in humans
Life Sciences 72: 2009
Horikoshi T, Fujii T, Kawashima K, Sakuragawa N (2003)
Acetylcholine increase in amniotic fluid of experimental rats for intrauterine growth retardation
Life Sciences 72: 2145
Horiuchi Y, Fujii T, Kamimura Y, Kawashima K (2003)
The endogenous, immunologically active peptide apelin inhibits lymphocytic cholinergic activity during immunological responses
Journal of Neuroimmunology 144: 46
Horiuchi Y, Kimura R, Kato N, Fujii T, Seki M, Endo T, Kato T, Kawashima K (2003)
Evolutional study on acetylcholine expression
Life Sciences 72: 1745
Kamimura Y, Fujii T, Kojima H, Nagano T, Kawashima K (2003)
Nitric oxide (NO) synthase mRNA expression and NO production via muscarinic acetylcholine receptor-mediated pathways in the CEM, human leukemic T-cell line
Life Sciences 72: 2151
Kawashima K, Fujii T (2003)
The lymphocytic cholinergic system and its contribution to the regulation of immune activity
Life Sciences 74: 675
Kawashima K, Fujii T (2003)
The lymphocytic cholinergic system and its biological function
Life Sciences 72: 2101
Kimura R, Ushiyama N, Fujii T, Kawashima K (2003)
Nicotine-induced Ca2+ signaling and down-regulation of nicotinic acetylcholine receptor subunit expression in the CEM human leukemic T-cell line
Life Sciences 72: 2155
Nakamura Y, Kaneko T, Sato S, Mimuro M, Miyashita H, Tsuchiya T, Sasamoto S, Watanabe A, Kawashima K, Kishida Y, Kiyokawa C, Kohara M, Matsumoto M, Matsuno A, Nakazaki N, Shimpo S, Takeuchi C, Yamada M, Tabata S (2003)
Complete genome structure of Gloeobacter violaceus PCC 7421, a cyanobacterium that lacks thylakoids
DNA Research 10: 137
Nakamura Y, Kaneko T, Sato S, Mimuro M, Miyashita H, Tsuchiya T, Sasamoto S, Watanabe A, Kawashima K, Kishida Y, Kiyokawa C, Kohara M, Matsumoto M, Matsuno A, Nakazaki N, Shimpo S, Takeuchi C, Yamada M, Tabata S (2003)
Complete genome structure of Gloeobacter violaceus PCC 7421, a cyanobacterium that lacks thylakoids (supplement)
DNA Research 10: 181
Ogawa H, Fujii T, Watanabe Y, Kawashima K (2003)
Expression of multiple mRNA species for choline acetyltransferase in human T-lymphocytes
Life Sciences 72: 2127
Shimizu I, Kawashima K, Ishii D, Oka M (2003)
Urodynamics in a rat neurogenic bladder model with a unilateral electrolytic lesion of the basal forebrain
BJU Int 91: 861
Suzuki T, Matsugi T, Takagi R, Kawashima K (2003)
Endogenous glutamatergic synaptic activity elicits acetylcholine release from rat cultured septal cells
Neurosci Res 47: 341
Fujii T, Ushiyama N, Hosonuma K, Suenaga A, Kawashima K (2002)
Effects of human antithymocyte globulin on acetylcholine synthesis, its release and choline acetyltransferase transcription in a human leukemic T-cell line
Journal of Neuroimmunology 128: 1
Kaneko T, Nakamura Y, Sato S, Minamisawa K, Uchiumi T, Sasamoto S, Watanabe A, Idesawa K, Iriguchi M, Kawashima K, Kohara M, Matsumoto M, Shimpo S, Tsuruoka H, Wada T, Yamada M, Tabata S (2002)
Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110 (supplement)
DNA Research 9: 225
Kaneko T, Nakamura Y, Sato S, Minamisawa K, Uchiumi T, Sasamoto S, Watanabe A, Idesawa K, Iriguchi M, Kawashima K, Kohara M, Matsumoto M, Shimpo S, Tsuruoka H, Wada T, Yamada M, Tabata S (2002)
Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110
DNA Research 9: 189
Nakamura Y, Kaneko T, Sato S, Ikeuchi M, Katoh H, Sasamoto S, Watanabe A, Iriguchi M, Kawashima K, Kimura T, Kishida Y, Kiyokawa C, Kohara M, Matsumoto M, Matsuno A, Nakazaki N, Shimpo S, Sugimoto M, Takeuchi C, Yamada M, Tabata S (2002)
Complete genome structure of the thermophilic cyanobacterium Thermosynechococcus elongatus BP-1
DNA Research 9: 123
Fujii T, Kawashima K (2001)
An independent non-neuronal cholinergic system in lymphocytes
Japanese Journal of Pharmacology 85: 11
Fujimoto K, Matsui M, Fujii T, Kawashima K (2001)
Decreased acetylcholine content and choline acetyltransferase mRNA expression in circulating mononuclear leukocytes and lymphoid organs of the spontaneously hypertensive rat
Life Sciences 69: 1629
Jacoby DB, Yost BL, Kumaravel B, Chan-Li Y, Xiao HQ, Kawashima K, Fryer AD (2001)
Glucocorticoid treatment increases inhibitory m(2) muscarinic receptor expression and function in the airways
American Journal of Respiratory Cellular & Molecular Biology 24: 485
Kaneko T, Nakamura Y, Wolk CP, Kuritz T, Sasamoto S, Watanabe A, Iriguchi M, Ishikawa A, Kawashima K, Kimura T, Kishida Y, Kohara M, Matsumoto M, Matsuno A, Muraki A, Nakazaki N, Shimpo S, Sugimoto M, Takazawa M, Yamada M, Yasuda M, Tabata S (2001)
Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120
DNA Research 8: 205
Sakuragawa N, Elwan MA, Uchida S, Fujii T, Kawashima K (2001)
Non-neuronal neurotransmitters and neurotrophic factors in amniotic epithelial cells: expression and function in humans and monkey
Japanese Journal of Pharmacology 85: 20
Suzuki T, Matsugi T, Takagi R, Kanagawa M, Hirata M, Nakamura T, Kudo Y, Kawashima K (2001)
Functional expression of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors precedes the development of cholinergic phenotype in embryonic rat septal cells in culture
Neuroscience Letters 311: 89
Fujii T, Nakai K, Nakajima Y, Kawashima K (2000)
Enhancement of hippocampal cholinergic neurotransmission through 5-HT1A receptor-mediated pathways by repeated lithium treatment in rats
Canadian Journal of Physiology & Pharmacology 78: 392
Fujii T, Harada H, Koyama T, Nakajima Y, Kawashima K (2000)
Effects of physostigmine and calcium on acetylcholine efflux from the hippocampus of freely moving rats as determined by in vivo microdialysis and a radioimmunoassay
Neuroscience Letters 289: 181
Fujii T, Kawashima K (2000)
Ca2+ oscillation and c-fos gene expression induced via muscarinic acetylcholine receptor in human T- and B-cell lines
Naunyn Schmiedebergs Arch Pharmacol 362: 14
Fujii T, Kawashima K (2000)
Calcium signaling and c-Fos gene expression via M3 muscarinic acetylcholine receptors in human T- and B-cells
Japanese Journal of Pharmacology 84: 124
Fujii T, Kawashima K (2000)
YM905, a novel M3 antagonist, inhibits Ca2+ signaling and c-fos gene expression mediated via muscarinic receptors in human T cells
General Pharmacology 35: 71
Harada H, Hosonuma K, Fujii T, Kawashima K (2000)
Enhancement of cerebral cortical acetylcholine release by intraperitoneal acetic acid and its suppression by analgesics in freely moving rats
Neuroscience Letters 284: 163
Kaneko T, Nakamura Y, Sato S, Asamizu E, Kato T, Sasamoto S, Watanabe A, Idesawa K, Ishikawa A, Kawashima K, Kimura T, Kishida Y, Kiyokawa C, Kohara M, Matsumoto M, Matsuno A, Mochizuki Y, Nakayama S, Nakazaki N, Shimpo S, Sugimoto M, Takeuchi C, Yamada M, Tabata S (2000)
Complete genome structure of the nitrogen-fixing symbiotic bacterium Mesorhizobium loti
DNA Research 7: 331
Kawashima K, Fujii T (2000)
Extraneuronal cholinergic system in lymphocytes
Pharmacol Ther 86: 29
Salanoubat M, Lemcke K, Rieger M, Ansorge W, Unseld M, Fartmann B, Valle G, Blocker H, Perez-Alonso M, Obermaier B, Delseny M, Boutry M, Grivell LA, Mache R, Puigdomenech P, de Simone V, Choisne N, Artiguenave F, Robert C, Brottier P, Wincker P, Cattolico L, Weissenbach J, Saurin W, Quetier F, Schafer M, Muller-Auer S, Gabel C, Fuchs M, Benes V, Wurmbach E, Drzonek H, Erfle H, Jordan N, Bangert S, Wiedelmann R, Kranz H, Voss H, Holland R, Brandt P, Nyakatura G, Vezzi A, D'Angelo M, Pallavicini A, Toppo S, Simionati B, Conrad A, Hornischer K, Kauer G, Lohnert TH, Nordsiek G, Reichelt J, Scharfe M, Schon O, Bargues M, Terol J, Climent J, Navarro P, Collado C, Perez-Perez A, Ottenwalder B, Duchemin D, Cooke R, Laudie M, Berger-Llauro C, Purnelle B, Masuy D, de Haan M, Maarse AC, Alcaraz JP, Cottet A, Casacuberta E, Monfort A, Argiriou A, Flores M, Liguori R, Vitale D, Mannhaupt G, Haase D, Schoof H, Rudd S, Zaccaria P, Mewes HW, Mayer KF, Kaul S, Town CD, Koo HL, Tallon LJ, Jenkins J, Rooney T, Rizzo M, Walts A, Utterback T, Fujii CY, Shea TP, Creasy TH, Haas B, Maiti R, Wu D, Peterson J, Van Aken S, Pai G, Militscher J, Sellers P, Gill JE, Feldblyum TV, Preuss D, Lin X, Nierman WC, Salzberg SL, White O, Venter JC, Fraser CM, Kaneko T, Nakamura Y, Sato S, Kato T, Asamizu E, Sasamoto S, Kimura T, Idesawa K, Kawashima K, Kishida Y, Kiyokawa C, Kohara M, Matsumoto M, Matsuno A, Muraki A, Nakayama S, Nakazaki N, Shinpo S, Takeuchi C, Wada T, Watanabe A, Yamada M, Yasuda M, Tabata S (2000)
Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana
Nature 408: 820
Tabata S, Kaneko T, Nakamura Y, Kotani H, Kato T, Asamizu E, Miyajima N, Sasamoto S, Kimura T, Hosouchi T, Kawashima K, Kohara M, Matsumoto M, Matsuno A, Muraki A, Nakayama S, Nakazaki N, Naruo K, Okumura S, Shinpo S, Takeuchi C, Wada T, Watanabe A, Yamada M, Yasuda M, Sato S, de la Bastide M, Huang E, Spiegel L, Gnoj L, O'Shaughnessy A, Preston R, Habermann K, Murray J, Johnson D, Rohlfing T, Nelson J, Stoneking T, Pepin K, Spieth J, Sekhon M, Armstrong J, Becker M, Belter E, Cordum H, Cordes M, Courtney L, Courtney W, Dante M, Du H, Edwards J, Fryman J, Haakensen B, Lamar E, Latreille P, Leonard S, Meyer R, Mulvaney E, Ozersky P, Riley A, Strowmatt C, Wagner-McPherson C, Wollam A, Yoakum M, Bell M, Dedhia N, Parnell L, Shah R, Rodriguez M, See LH, Vil D, Baker J, Kirchoff K, Toth K, King L, Bahret A, Miller B, Marra M, Martienssen R, McCombie WR, Wilson RK, Murphy G, Bancroft I, Volckaert G, Wambutt R, Dusterhoft A, Stiekema W, Pohl T, Entian KD, Terryn N, Hartley N, Bent E, Johnson S, Langham SA, McCullagh B, Robben J, Grymonprez B, Zimmermann W, Ramsperger U, Wedler H, Balke K, Wedler E, Peters S, van Staveren M, Dirkse W, Mooijman P, Lankhorst RK, Weitzenegger T, Bothe G, Rose M, Hauf J, Berneiser S, Hempel S, Feldpausch M, Lamberth S, Villarroel R, Gielen J, Ardiles W, Bents O, Lemcke K, Kolesov G, Mayer K, Rudd S, Schoof H, Schueller C, Zaccaria P, Mewes HW, Bevan M, Fransz P (2000)
Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana
Nature 408: 823
Fujii T, Ohba S, Nakai K, Fujimoto K, Suzuki T, Kawashima K (1999)
Enhancement of the serotonin-mediated acetylcholine release by repeated desmethylimipramine treatment in the hippocampus of freely moving rats
Japanese Journal of Pharmacology 80: 303
Fujii T, Tajima S, Yamada S, Watanabe Y, Sato KZ, Matsui M, Misawa H, Kasahara T, Kawashima K (1999)
Constitutive expression of mRNA for the same choline acetyltransferase as that in the nervous system, an acetylcholine-synthesizing enzyme, in human leukemic T-cell lines
Neuroscience Letters 259: 71
Koyama T, Nakajima Y, Fujii T, Kawashima K (1999)
Enhancement of cortical and hippocampal cholinergic neurotransmission through 5-HT1A receptor-mediated pathways by BAY x 3702 in freely moving rats
Neuroscience Letters 265: 33
Ono A, Kawashima K, Sekita K, Hirose A, Ogawa Y, Saito M, Naito K, Yasuhara K, Kaneko T, Furuya T, Inoue T, Kurokawa Y (1999)
Toluene inhalation induced epididymal sperm dysfunction in rats
Toxicology 139: 193
Oosawa H, Fujii T, Kawashima K (1999)
Nerve growth factor increases the synthesis and release of acetylcholine and the expression of vesicular acetylcholine transporter in primary cultured rat embryonic septal cells
Journal of Neuroscience Research 57: 381
Rinner I, Globerson A, Kawashima K, Korsatko W, Schauenstein K (1999)
A possible role for acetylcholine in the dialogue between thymocytes and thymic stroma
Neuroimmunomodulation 6: 51
Sakuragawa N, Elwan MA, Fujii T, Kawashima K (1999)
Possible dynamic neurotransmitter metabolism surrounding the fetus
Journal of Child Neurology 14: 265
Sato KZ, Fujii T, Watanabe Y, Yamada S, Ando T, Kazuko F, Kawashima K (1999)
Diversity of mRNA expression for muscarinic acetylcholine receptor subtypes and neuronal nicotinic acetylcholine receptor subunits in human mononuclear leukocytes and leukemic cell lines
Neuroscience Letters 266: 17
Fujii T, Yamada S, Watanabe Y, Misawa H, Tajima S, Fujimoto K, Kasahara T, Kawashima K (1998)
Induction of choline acetyltransferase mRNA in human mononuclear leukocytes stimulated by phytohemagglutinin, a T-cell activator
Journal of Neuroimmunology 82: 101
Kawashima K, Fujii T, Watanabe Y, Misawa H (1998)
Acetylcholine synthesis and muscarinic receptor subtype mRNA expression in T-lymphocytes
Life Sciences 62: 1701
Nakai K, Fujii T, Fujimoto K, Suzuki T, Kawashima K (1998)
Effect of WAY-100135 on the hippocampal acetylcholine release potentiated by 8-OH-DPAT, a serotonin1A receptor agonist, in normal and p-chlorophenylalanine-treated rats as measured by in vivo microdialysis
Neurosci Res 31: 23
Rinner I, Kawashima K, Schauenstein K (1998)
Rat lymphocytes produce and secrete acetylcholine in dependence of differentiation and activation
Journal of Neuroimmunology 81: 31
Fujii T, Mori Y, Tominaga T, Hayasaka I, Kawashima K (1997)
Maintenance of constant blood acetylcholine content before and after feeding in young chimpanzees
Neuroscience Letters 227: 21
Fujii T, Yoshizawa M, Nakai K, Fujimoto K, Suzuki T, Kawashima K (1997)
Demonstration of the facilitatory role of 8-OH-DPAT on cholinergic transmission in the rat hippocampus using in vivo microdialysis
Brain Research 761: 244
Suzuki T, Nakajima K, Fujimoto K, Fujii T, Kawashima K (1997)
Nitric oxide increases stimulation-evoked acetylcholine release from rat hippocampal slices by a cyclic GMP-independent mechanism
Brain Research 760: 158
Yamada S, Fujii T, Kawashima K (1997)
Oral administration of KW-5092, a novel gastroprokinetic agent with acetylcholinesterase inhibitory and acetylcholine release enhancing activities, causes a dose-dependent increase in the blood acetylcholine content of beagle dogs
Neuroscience Letters 225: 25
Fujii T, Tsuchiya T, Yamada S, Fujimoto K, Suzuki T, Kasahara T, Kawashima K (1996)
Localization and synthesis of acetylcholine in human leukemic T cell lines
Journal of Neuroscience Research 44: 66
Kinoshita K, Kawashima K, Kawashima Y, Fukuchi I, Yamamura M, Matsuoka Y (1996)
Effect of TA-0910, a novel thyrotropin-releasing hormone analog, on in vivo acetylcholine release and turnover in rat brain
Japanese Journal of Pharmacology 71: 139
Yamada H, Otsuka M, Fujimoto K, Kawashima K, Yoshida M (1996)
Determination of acetylcholine concentration in cerebrospinal fluid of patients with neurologic diseases
Acta Neurologica Scandinavica 93: 76
Fujii T, Yamada S, Yamaguchi N, Fujimoto K, Suzuki T, Kawashima K (1995)
Species differences in the concentration of acetylcholine, a neurotransmitter, in whole blood and plasma
Neuroscience Letters 201: 207
Ikeda C, Morita I, Mori A, Fujimoto K, Suzuki T, Kawashima K, Murota S (1994)
Phorbol ester stimulates acetylcholine synthesis in cultured endothelial cells isolated from porcine cerebral microvessels
Brain Research 655: 147
Ishii Y, Kojima J, Ikeda N, Kawashima K (1994)
Effect of NIK-247 on basal concentrations of extracellular acetylcholine in the cerebral cortex of conscious, freely moving rats
Japanese Journal of Pharmacology 66: 289
Kawashima K, Sato A, Yoshizawa M, Fujii T, Fujimoto K, Suzuki T (1994)
Effects of the centrally acting cholinesterase inhibitors tetrahydroaminoacridine and E2020 on the basal concentration of extracellular acetylcholine in the hippocampus of freely moving rats
Naunyn Schmiedebergs Arch Pharmacol 350: 523
Suzuki T, Nonaka H, Fujimoto K, Kawashima K (1994)
Tacrine increases stimulation-evoked acetylcholine release from rat hippocampal slices
Japanese Journal of Pharmacology 65: 337
Suzuki T, Kanagawa M, Takada Y, Fujimoto K, Kawashima K (1994)
Nerve growth factor treatment induces high-potassium-evoked calcium-dependent acetylcholine release in cultured embryonic rat septal cells
Brain Research 665: 311
Suzuki T, Nonaka H, Fujimoto K, Kawashima K (1993)
Effects of physostigmine and some nitric oxide-cyclic GMP-related compounds on muscarinic receptor-mediated autoinhibition of hippocampal acetylcholine release
Journal of Neurochemistry 60: 2285
Suzuki T, Kashima Y, Fujimoto K, Kawashima K (1992)
Acetylcholine synthesis is modulated by acetylcholine content of cytosolic fraction but not by that of releasable fraction
Neuroscience Letters 144: 127
Kawashima K, Hayakawa T, Kashima Y, Suzuki T, Fujimoto K, Oohata H (1991)
Determination of acetylcholine release in the striatum of anesthetized rats using in vivo microdialysis and a radioimmunoassay
Journal of Neurochemistry 57: 882
Kobayashi N, Sakuma M, Yoshioka K, Onishi Y, Yanagisawa M, Kawashima K, Otsuka M (1991)
Substance P-evoked release of acetylcholine from isolated spinal cord of the newborn rat
Neuroscience 45: 331
Suzuki T, Kashima Y, Fujimoto K, Oohata H, Kawashima K (1991)
Regional differences in extracellular choline dependency of acetylcholine synthesis in the rat brain
Neurosci Res 11: 71
Kawashima K, Fujimoto K, Suzuki T, Oohata H (1990)
Pharmacological differentiation of presynaptic M1 muscarinic receptors modulating acetylcholine release from postsynaptic muscarinic receptors in guinea-pig ileum
General Pharmacology 21: 17
Kawashima K, Watanabe N, Oohata H, Fujimoto K, Suzuki T, Ishizaki Y, Morita I, Murota S (1990)
Synthesis and release of acetylcholine by cultured bovine arterial endothelial cells
Neuroscience Letters 119: 156
Kawashima K, Oohata H, Fujimoto K, Suzuki T (1989)
Extraneuronal localization of acetylcholine and its release upon nicotinic stimulation in rabbits
Neuroscience Letters 104: 336
Suzuki T, Fujimoto K, Oohata H, Kawashima K (1989)
Effects of TRH and DN-1417 on high potassium-evoked acetylcholine release from rat basal forebrain slices determined directly by radioimmunoassay
General Pharmacology 20: 239
Suzuki T, Kashima Y, Kawashima K (1989)
Hemicholinium-3-resistant choline uptake system linked to acetylcholine synthesis in the rat hippocampus
Neuroscience Letters 105: 211
Kawashima K, Fujimoto K, Suzuki T, Oohata H (1988)
Direct determination of acetylcholine release by radioimmunoassay and presence of presynaptic M1 muscarinic receptors in guinea pig ileum
Journal of Pharmacology & Experimental Therapeutics 244: 1036
Suzuki T, Fujimoto K, Oohata H, Kawashima K (1988)
Presynaptic M1 muscarinic receptor modulates spontaneous release of acetylcholine from rat basal forebrain slices
Neuroscience Letters 84: 209
Kawashima K, Oohata H, Fujimoto K, Suzuki T (1987)
Plasma concentration of acetylcholine in young women
Neuroscience Letters 80: 339
Kawashima K, Yoshida N, Kadokawa T (1986)
Pharmacological properties of the novel antimuscarinic agent 4-[2-(1,2-benzisoxazol-3-yl)-2-(hexahydro-1H-azepin-1-yl)a cetoxy]-1-et hyl-1- methylpiperidinium iodide
Arzneimittelforschung 36: 927
Murakami N, Takahashi K, Kawashima K (1984)
Effect of light on the acetylcholine concentrations of the suprachiasmatic nucleus in the rat
Brain Research 311: 358
Takayanagi I, Sone H, Kawashima K, Sohji Y, Kadokawa T (1982)
A possible mechanism of a new antispasmodic drug, 2-(1,2-benzisoxazol-3-yl)-3-[2-(2-piperidinoethoxy) phenyl]acrylonitrile (SX-284)
Japanese Journal of Pharmacology 32: 973
Kawashima K, Ishikawa H, Mochizuki M (1980)
Radioimmunoassay for acetylcholine in the rat brain
J Pharmacol Methods 3: 115
Sohji Y, Kawashima K, Shimizu M (1978)
[Pharmacological studies of loperamide, an anti-diarrheal agent. III. Interaction between loperamide and various agonists in the guinea pig intestine (author's transl)]
Nihon Yakurigaku Zasshi 74: 213