Cogan DP, Zhang K, Li X, Li S, Pintilie GD, Roh SH, Craik CS, Chiu W, Khosla C (2021) <br />Mapping the catalytic conformations of an assembly-line polyketide synthase module<br /><i>Science</i> <b>374</b>: 729<br /><br />Li X, Sevillano N, La Greca F, Deis L, Liu YC, Deller MC, Mathews, II, Matsui T, Cane DE, Craik CS, Khosla C (2018) <br />Structure-Function Analysis of the Extended Conformation of a Polyketide Synthase Module<br /><i>Journal of the American Chemical Society</i> <b>140</b>: 6518<br /><br />Li X, Sevillano N, La Greca F, Hsu J, Mathews, II, Matsui T, Craik CS, Khosla C (2018) <br />Discovery and Characterization of a Thioesterase-Specific Monoclonal Antibody That Recognizes the 6-Deoxyerythronolide B Synthase<br /><i>Biochemistry</i> <b>57</b>: 6201<br /><br />Gass J, Khosla C (2007) <br />Prolyl endopeptidases<br /><i>Cell Mol Life Sciences</i> <b>64</b>: 345<br /><br />Shan L, Mathews, II, Khosla C (2005) <br />Structural and mechanistic analysis of two prolyl endopeptidases: role of interdomain dynamics in catalysis and specificity<br /><i>Proc Natl Acad Sci U S A</i> <b>102</b>: 3599<br /><br />Hu Z, Pfeifer BA, Chao E, Murli S, Kealey J, Carney JR, Ashley G, Khosla C, Hutchinson CR (2003) <br />A specific role of the Saccharopolyspora erythraea thioesterase II gene in the function of modular polyketide synthases<br /><i>Microbiology</i> <b>149</b>: 2213<br /><br />Yin Y, Lu H, Khosla C, Cane DE (2003) <br />Expression and kinetic analysis of the substrate specificity of modules 5 and 6 of the picromycin/methymycin polyketide synthase<br /><i>Journal of the American Chemical Society</i> <b>125</b>: 5671<br /><br />Tsai SC, Lu H, Cane DE, Khosla C, Stroud RM (2002) <br />Insights into channel architecture and substrate specificity from crystal structures of two macrocycle-forming thioesterases of modular polyketide synthases<br /><i>Biochemistry</i> <b>41</b>: 12598<br /><br />Chiu HT, Hubbard BK, Shah AN, Eide J, Fredenburg RA, Walsh CT, Khosla C (2001) <br />Molecular cloning and sequence analysis of the complestatin biosynthetic gene cluster<br /><i>Proc Natl Acad Sci U S A</i> <b>98</b>: 8548<br /><br />Tsai SC, Miercke LJ, Krucinski J, Gokhale R, Chen JC, Foster PG, Cane DE, Khosla C, Stroud RM (2001) <br />Crystal structure of the macrocycle-forming thioesterase domain of the erythromycin polyketide synthase: versatility from a unique substrate channel<br /><i>Proc Natl Acad Sci U S A</i> <b>98</b>: 14808<br /><br />Julien B, Shah S, Ziermann R, Goldman R, Katz L, Khosla C (2000) <br />Isolation and characterization of the epothilone biosynthetic gene cluster from Sorangium cellulosum<br /><i>Gene</i> <b>249</b>: 153<br /><br />Tang L, Shah S, Chung L, Carney J, Katz L, Khosla C, Julien B (2000) <br />Cloning and heterologous expression of the epothilone gene cluster<br /><i>Science</i> <b>287</b>: 640<br /><br />