Bradic I, Kuentzel KB, Honeder S, Grabner GF, Vujic N, Zimmermann R, Birner-Gruenberger R, Kratky D (2022)
Off-target effects of the lysosomal acid lipase inhibitors Lalistat-1 and Lalistat-2 on neutral lipid hydrolases
Mol Metab

Goeritzer M, Schlager S, Kuentzel KB, Vujic N, Korbelius M, Rainer S, Kolb D, Mussbacher M, Salzmann M, Schrottmaier WC, Assinger A, Schlagenhauf A, Madreiter-Sokolowski CT, Blass S, Eichmann TO, Graier WF, Kratky D (2022)
Adipose Triglyceride Lipase Deficiency Attenuates In Vitro Thrombus Formation without Affecting Platelet Activation and Bleeding In Vivo
Cells 11:

Kuentzel KB, Bradic I, Mihalic ZN, Korbelius M, Rainer S, Pirchheim A, Kargl J, Kratky D (2022)
Dysregulation of Placental Lipid Hydrolysis by High-Fat/High-Cholesterol Feeding and Gestational Diabetes Mellitus in Mice
Int J Mol Sci 23:

Helderman RC, Whitney DG, Duta-Mare M, Akhmetshina A, Vujic N, Jayapalan S, Nyman JS, Misra BB, Rosen CJ, Czech MP, Kratky D, Rendina-Ruedy E (2021)
Loss of Function of Lysosomal Acid Lipase (LAL) Profoundly Impacts Osteoblastogenesis and Increases Fracture Risk in Humans
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Kuentzel KB, Bradic I, Akhmetshina A, Korbelius M, Rainer S, Kolb D, Gauster M, Vujic N, Kratky D (2021)
Defective Lysosomal Lipolysis Causes Prenatal Lipid Accumulation and Exacerbates Immediately after Birth
Int J Mol Sci 22:

Schilcher I, Stadler JT, Lechleitner M, Hrzenjak A, Berghold A, Pregartner G, Lhomme M, Holzer M, Korbelius M, Reichmann F, Springer A, Wadsack C, Madl T, Kratky D, Kontush A, Marsche G, Frank S (2021)
Endothelial Lipase Modulates Paraoxonase 1 Content and Arylesterase Activity of HDL
Int J Mol Sci 22:

Radulovic S, Gottschalk B, Horl G, Zardoya-Laguardia P, Schilcher I, Hallstrom S, Vujic N, Schmidt K, Trieb M, Graier WF, Malli R, Kratky D, Marsche G, Frank S (2020)
Endothelial lipase increases eNOS activating capacity of high-density lipoprotein
Biochimica & Biophysica Acta Molecular & Cellular Biology Lipids 1865: 158612

Schittmayer M, Vujic N, Darnhofer B, Korbelius M, Honeder S, Kratky D, Birner-Gruenberger R (2020)
Spatially resolved activity-based proteomic profiles of the murine small intestinal lipases
Mol Cell Proteomics 19: 2104

Korbelius M, Vujic N, Sachdev V, Obrowsky S, Rainer S, Gottschalk B, Graier WF, Kratky D (2019)
ATGL/CGI-58-Dependent Hydrolysis of a Lipid Storage Pool in Murine Enterocytes
Cell Rep 28: 1923

Leopold C, Duta-Mare M, Sachdev V, Goeritzer M, Maresch LK, Kolb D, Reicher H, Wagner B, Stojakovic T, Ruelicke T, Haemmerle G, Hoefler G, Sattler W, Kratky D (2019)
Hepatocyte-specific lysosomal acid lipase deficiency protects mice from diet-induced obesity but promotes hepatic inflammation
Biochimica & Biophysica Acta Molecular & Cellular Biology Lipids 1864: 500

Maresch LK, Benedikt P, Feiler U, Eder S, Zierler KA, Taschler U, Kolleritsch S, Eichmann TO, Schoiswohl G, Leopold C, Wieser BI, Lackner C, Rulicke T, van Klinken J, Kratky D, Moustafa T, Hoefler G, Haemmerle G (2019)
Intestine-Specific Overexpression of Carboxylesterase 2c Protects Mice From Diet-Induced Liver Steatosis and Obesity
Hepatol Commun 3: 227

Duta-Mare M, Sachdev V, Leopold C, Kolb D, Vujic N, Korbelius M, Hofer DC, Xia W, Huber K, Auer M, Gottschalk B, Magnes C, Graier WF, Prokesch A, Radovic B, Bogner-Strauss JG, Kratky D (2018)
Lysosomal acid lipase regulates fatty acid channeling in brown adipose tissue to maintain thermogenesis
Biochimica & Biophysica Acta 1863: 467

Xia W, Pessentheiner AR, Hofer DC, Amor M, Schreiber R, Schoiswohl G, Eichmann TO, Walenta E, Itariu B, Prager G, Hackl H, Stulnig T, Kratky D, Rulicke T, Bogner-Strauss JG (2018)
Loss of ABHD15 Impairs the Anti-lipolytic Action of Insulin by Altering PDE3B Stability and Contributes to Insulin Resistance
Cell Rep 23: 1948

Schilcher I, Kern S, Hrzenjak A, Eichmann TO, Stojakovic T, Scharnagl H, Duta-Mare M, Kratky D, Marsche G, Frank S (2017)
Impact of Endothelial Lipase on Cholesterol Efflux Capacity of Serum and High-density Lipoprotein
Sci Rep 7: 12485

Schlager S, Vujic N, Korbelius M, Duta-Mare M, Dorow J, Leopold C, Rainer S, Wegscheider M, Reicher H, Ceglarek U, Sattler W, Radovic B, Kratky D (2017)
Lysosomal lipid hydrolysis provides substrates for lipid mediator synthesis in murine macrophages
Oncotarget 8: 40037

Vujic N, Korbelius M, Leopold C, Duta-Mare M, Rainer S, Schlager S, Goeritzer M, Kolb D, Eichmann TO, Diwoky C, Zimmer A, Zimmermann R, Lass A, Radovic B, Kratky D (2017)
Monoglyceride lipase deficiency affects hepatic cholesterol metabolism and lipid-dependent gut transit in ApoE-/- mice
Oncotarget 8: 33122

Grumet L, Eichmann TO, Taschler U, Zierler KA, Leopold C, Moustafa T, Radovic B, Romauch M, Yan C, Du H, Haemmerle G, Zechner R, Fickert P, Kratky D, Zimmermann R, Lass A (2016)
Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover
Journal of Biological Chemistry 291: 17977

Radovic B, Vujic N, Leopold C, Schlager S, Goeritzer M, Patankar JV, Korbelius M, Kolb D, Reindl J, Wegscheider M, Tomin T, Birner-Gruenberger R, Schittmayer M, Groschner L, Magnes C, Diwoky C, Frank S, Steyrer E, Du H, Graier WF, Madl T, Kratky D (2016)
Lysosomal acid lipase regulates VLDL synthesis and insulin sensitivity in mice
Diabetologia 59: 1743

Goeritzer M, Vujic N, Schlager S, Chandak PG, Korbelius M, Gottschalk B, Leopold C, Obrowsky S, Rainer S, Doddapattar P, Aflaki E, Wegscheider M, Sachdev V, Graier WF, Kolb D, Radovic B, Kratky D (2015)
Active autophagy but not lipophagy in macrophages with defective lipolysis
Biochimica & Biophysica Acta 1851: 1304

Schlager S, Goeritzer M, Jandl K, Frei R, Vujic N, Kolb D, Strohmaier H, Dorow J, Eichmann TO, Rosenberger A, Wolfler A, Lass A, Kershaw EE, Ceglarek U, Dichlberger A, Heinemann A, Kratky D (2015)
Adipose triglyceride lipase acts on neutrophil lipid droplets to regulate substrate availability for lipid mediator synthesis
J Leukoc Biol 98: 837

Vujic N, Schlager S, Eichmann TO, Madreiter-Sokolowski CT, Goeritzer M, Rainer S, Schauer S, Rosenberger A, Woelfler A, Doddapattar P, Zimmermann R, Hoefler G, Lass A, Graier WF, Radovic B, Kratky D (2015)
Monoglyceride lipase deficiency modulates endocannabinoid signaling and improves plaque stability in ApoE-knockout mice
Atherosclerosis 244: 9

Goeritzer M, Schlager S, Radovic B, Madreiter CT, Rainer S, Thomas G, Lord CC, Sacks J, Brown AL, Vujic N, Obrowsky S, Sachdev V, Kolb D, Chandak PG, Graier WF, Sattler W, Brown JM, Kratky D (2014)
Deletion of CGI-58 or adipose triglyceride lipase differently affects macrophage function and atherosclerosis
J Lipid Res 55: 2562

Walenta E, Pessentheiner AR, Pelzmann HJ, Deutsch A, Goeritzer M, Kratky D, Hackl H, Oh da Y, Prokesch A, Bogner-Strauss JG (2013)
alpha/beta-Hydrolase Domain Containing Protein 15 (ABHD15) - an Adipogenic Protein Protecting from Apoptosis
PLoS ONE 8: e79134

Obrowsky S, Chandak PG, Patankar JV, Pfeifer T, Povoden S, Schreiber R, Haemmerle G, Levak-Frank S, Kratky D (2012)
Cholesteryl ester accumulation and accelerated cholesterol absorption in intestine-specific hormone sensitive lipase-null mice
Biochimica & Biophysica Acta 1821: 1406

Lammers B, Chandak PG, Aflaki E, Van Puijvelde GH, Radovic B, Hildebrand RB, Meurs I, Out R, Kuiper J, van Berkel TJ, Kolb D, Haemmerle G, Zechner R, Levak-Frank S, Van Eck M, Kratky D (2011)
Macrophage adipose triglyceride lipase deficiency attenuates atherosclerotic lesion development in low-density lipoprotein receptor knockout mice
Arterioscler Thromb Vasc Biol 31: 67

Buchebner M, Pfeifer T, Rathke N, Chandak PG, Lass A, Schreiber R, Kratzer A, Zimmermann R, Sattler W, Koefeler H, Frohlich E, Kostner GM, Birner-Gruenberger R, Chiang KP, Haemmerle G, Zechner R, Levak-Frank S, Cravatt B, Kratky D (2010)
Cholesteryl ester hydrolase activity is abolished in HSL-/- macrophages but unchanged in macrophages lacking KIAA1363
J Lipid Res 51: 2896

Chandak PG, Radovic B, Aflaki E, Kolb D, Buchebner M, Frohlich E, Magnes C, Sinner F, Haemmerle G, Zechner R, Tabas I, Levak-Frank S, Kratky D (2010)
Efficient phagocytosis requires triacylglycerol hydrolysis by adipose triglyceride lipase
Journal of Biological Chemistry 285: 20192

Haemmerle G, Lass A, Zimmermann R, Gorkiewicz G, Meyer C, Rozman J, Heldmaier G, Maier R, Theussl C, Eder S, Kratky D, Wagner EF, Klingenspor M, Hoefler G, Zechner R (2006)
Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase
Science 312: 734

Kratky D, Zimmermann R, Wagner EM, Strauss JG, Jin W, Kostner GM, Haemmerle G, Rader DJ, Zechner R (2005)
Endothelial lipase provides an alternative pathway for FFA uptake in lipoprotein lipase-deficient mouse adipose tissue
J Clinical Investigation 115: 161

Haemmerle G, Zimmermann R, Strauss JG, Kratky D, Riederer M, Knipping G, Zechner R (2002)
Hormone-sensitive lipase deficiency in mice changes the plasma lipid profile by affecting the tissue-specific expression pattern of lipoprotein lipase in adipose tissue and muscle
Journal of Biological Chemistry 277: 12946

Kratky D, Strauss JG, Zechner R (2001)
Tissue-specific activity of lipoprotein lipase in skeletal muscle regulates the expression of uncoupling protein 3 in transgenic mouse models
Biochemical Journal 355: 647

Voshol PJ, Jong MC, Dahlmans VE, Kratky D, Levak-Frank S, Zechner R, Romijn JA, Havekes LM (2001)
In muscle-specific lipoprotein lipase-overexpressing mice, muscle triglyceride content is increased without inhibition of insulin-stimulated whole-body and muscle-specific glucose uptake
Diabetes 50: 2585