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Rutin hydrate relieves neuroinflammation in zebrafish models: Involvement of NF-kB pathway as a central network
Fish Shellfish Immunol 141: 109062
Si S, Zhao X, Su F, Lu H, Zhang D, Sun L, Wang F, Xu L (2023)
New advances in clinical application of neostigmine: no longer focusing solely on increasing skeletal muscle strength
Front Pharmacol 14: 1227496
Liu W, Wu L, Li D, Huang Y, Liu M, Tian C, Liu X, Jiang X, Hu X, Gao X, Xu Z, Lu H, Zhao Q (2022)
Discovery of novel tacrine derivatives as potent antiproliferative agents with CDKs inhibitory property
Bioorg Chem 126: 105875
Lu H, Diaz DJ, Czarnecki NJ, Zhu C, Kim W, Shroff R, Acosta DJ, Alexander BR, Cole HO, Zhang Y, Lynd NA, Ellington AD, Alper HS (2022)
Machine learning-aided engineering of hydrolases for PET depolymerization
Nature 604: 662
Lu H, Zhu C, Chen Y, Ruan Y, Fan L, Chen Q, Wei Q (2022)
LncRNA ABHD11-AS1 promotes tumor progression in papillary thyroid carcinoma by regulating EPS15L1/EGFR signaling pathway
Clin Transl Oncol 24: 1124
Zeng Z, Liu R, Cao W, Yang L, Lin Y, Bi X, Jiang T, Deng W, Wang S, Lu H, Sun F, Shen G, Chang M, Lu Y, Wu S, Hao H, Xu M, Chen X, Hu L, Zhang L, Wan G, Xie Y, Li M (2022)
Study on pathological and clinical characteristics of chronic HBV infected patients with HBsAg positive, HBV DNA negative, HBeAg negative
Front Immunol 13: 1113070
Zhao J, Xu Y, Lu H, Zhao D, Zheng J, Lin M, Liang X, Ding Z, Dong W, Yang M, Li W, Zhang C, Sun B, Li X (2022)
Molecular mechanism of LIP05 derived from Monascus purpureus YJX-8 for synthesizing fatty acid ethyl esters under aqueous phase
Front Microbiol 13: 1107104
Feng J, Lu H, Yang Y, Huang W, Cheng H, Kong H, Li L (2021)
SERS-ELISA determination of human carboxylesterase 1 using metal-organic framework doped with gold nanoparticles as SERS substrate
Mikrochim Acta 188: 280
Li Y, Chen H, Lu H, Zou Z (2021)
Prognostic Significance of Hematopoietic-cell Serglycin for the Survival of Hepatocellular Carcinoma: A Single-center Retrospective Study
Comb Chem High Throughput Screen 24: 986
Liu Y, Guo J, Zhang J, Deng Y, Xiong G, Fu J, Wei L, Lu H (2021)
Chlorogenic acid alleviates thioacetamide-induced toxicity and promotes liver development in zebrafish (Danio rerio) through the Wnt signaling pathway
Aquat Toxicol 242: 106039
Lu H, Diaz DJ, Czarnecki NJ, Zhu C, Kim W, Shroff R, Acosta DJ, Alexander B, Cole H, Zhang YJ, Lynd N, Ellington AD, Alper HS (2021)
Deep learning redesign of PETase for practical PET degrading applications
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Wang Z, Chen Y, Xiao H, Li S, Zhang T, Hu J, Lu H, Xie H (2021)
The Enhancement Effect of Acetylcholine and Pyridostigmine on Bone-Tendon Interface Healing in a Murine Rotator Cuff Model
Am J Sports Med
Cao L, Hu T, Lu H, Peng D (2020)
N-MYC Downstream Regulated Gene 4 (NDRG4), a Frequent Downregulated Gene through DNA Hypermethylation, plays a Tumor Suppressive Role in Esophageal Adenocarcinoma
Cancers (Basel) 12:
Cheng B, Zhang H, Hu J, Peng Y, Yang J, Liao X, Liu F, Guo J, Hu C, Lu H (2020)
The immunotoxicity and neurobehavioral toxicity of zebrafish induced by famoxadone-cymoxanil
Chemosphere 247: 125870
Cheng B, Jiang F, Su M, Zhou L, Zhang H, Cao Z, Liao X, Xiong G, Xiao J, Liu F, Lu H (2020)
Effects of lincomycin hydrochloride on the neurotoxicity of zebrafish
Ecotoxicology & Environmental Safety 201: 110725
Tora G, Kim SH, Pi Z, Johnson JA, Jiang J, Phillips M, Lloyd J, Abell LM, Lu H, Locke G, Adam LP, Taylor DS, Yin X, Behnia K, Zhao L, Yang R, Basso M, Caporuscio C, Chen AY, Liu E, Kirshgessner T, Onorato JM, Ryan C, Traeger SC, Gordon D, Wexler RR, Finlay HJ (2020)
Identification of Reversible Small Molecule Inhibitors of Endothelial Lipase (EL) That Demonstrate HDL-C Increase In Vivo
Journal of Medicinal Chemistry 63: 1660
Wen-Xia H, Zhong-Wen H, Min J, Han Z, Wei-Ze L, Li-Bin Y, Fei L, Lu H, Ning Z, Xiao-Feng L (2020)
Five novel and highly efficient endophytic fungi isolated from Huperzia serrata expressing huperzine A for the treatment of Alzheimer's disease
Applied Microbiology & Biotechnology 104: 9159
Yu L, Lu H, Yang X, Li R, Shi J, Yu Y, Ma C, Sun F, Zhang S, Zhang F (2020)
Diosgenin alleviates hypercholesterolemia via SRB1/CES-1/CYP7A1/FXR pathway in high-fat diet-fed rats
Toxicol Appl Pharmacol
Cao Z, Zou L, Wang H, Zhang H, Liao X, Xiao J, Zhang S, Lu H (2019)
Exposure to diclofop-methyl induces immunotoxicity and behavioral abnormalities in zebrafish embryos
Aquat Toxicol 214: 105253
Kim SH, Johnson JA, Jiang J, Parkhurst B, Phillips M, Pi Z, Qiao JX, Tora G, Ye Chen A, Liu E, Yin X, Yang R, Zhao L, Taylor DS, Basso M, Behnia K, Onorato J, Chen XQ, Abell LM, Lu H, Locke G, Caporuscio C, Adam LP, Gordon D, Wexler RR, Finlay HJ (2019)
Identification of substituted benzothiazole sulfones as potent and selective inhibitors of endothelial lipase
Bioorganic & Medicinal Chemistry Lett 29: 1918
Ma X, Sun Z, Han X, Li S, Jiang X, Chen S, Zhang J, Lu H (2019)
Neuroprotective Effect of Resveratrol via Activation of Sirt1 Signaling in a Rat Model of Combined Diabetes and Alzheimer's Disease
Front Neurosci 13: 1400
Wang H, Zhou L, Meng Z, Su M, Zhang S, Huang P, Jiang F, Liao X, Cao Z, Lu H (2019)
Clethodim exposure induced development toxicity and behaviour alteration in early stages of zebrafish life
Environ Pollut 255: 113218
Zhu TK, Du PP, Zeng LJ, Lu H, Zhao HM, Li YW, Mo CH, Cai QY (2019)
Variation in metabolism and degradation of di-n-butyl phthalate (DBP) by high- and low-DBP accumulating cultivars of rice (Oryza sativa L.) and crude enzyme extracts
Sci Total Environ 668: 1117
Cai X, Li Q, Xiao L, Lu H, Tang J, Huang J, Yuan J (2018)
Insecticidal and Acetylcholinesterase Inhibition Activity of Veratrum nigrum Alkaloidal Extract against the German Cockroach (Blattella germanica)
J Arthropod Borne Dis 12: 414
Johnson JA, Tora G, Pi Z, Phillips M, Yin X, Yang R, Zhao L, Chen AY, Taylor DS, Basso M, Rose A, Behnia K, Onorato J, Chen XQ, Abell LM, Lu H, Locke G, Caporuscio C, Galella M, Adam LP, Gordon D, Wexler RR, Finlay HJ (2018)
Sulfonylated Benzothiazoles as Inhibitors of Endothelial Lipase
ACS Med Chem Lett 9: 1263
Wei W, Wang M, Li Y, Meng Q, Tang Y, Lu H, Yu W, Cheng Q, Xu L, Jian S, Wu Y, Yi X, Xie K (2018)
Muscarinic cholinergic signaling and overactive bladder-like symptoms associated with invasive bladder cancer
Oncol Lett 16: 775
Zhang P, Lu H, Peixoto RT, Pines MK, Ge Y, Oku S, Siddiqui TJ, Xie Y, Wu W, Archer-Hartmann S, Yoshida K, Tanaka KF, Aricescu AR, Azadi P, Gordon MD, Sabatini BL, Wong ROL, Craig AM (2018)
Heparan Sulfate Organizes Neuronal Synapses through Neurexin Partnerships
Cell 174: 1450
Zhao HM, Hu RW, Chen XX, Chen XB, Lu H, Li YW, Li H, Mo CH, Cai QY, Wong MH (2018)
Biodegradation pathway of di-(2-ethylhexyl) phthalate by a novel Rhodococcus pyridinivorans XB and its bioaugmentation for remediation of DEHP contaminated soil
Sci Total Environ 640-641: 1121
Zhou K, Yu W, Cao X, Shen P, Lu H, Luo Q, Rossen JWA, Xiao Y (2018)
Characterization of the population structure, drug resistance mechanisms and plasmids of the community-associated Enterobacter cloacae complex in China
J Antimicrob Chemother 73: 66
Connor SA, Ammendrup-Johnsen I, Chan AW, Kishimoto Y, Murayama C, Kurihara N, Tada A, Ge Y, Lu H, Yan R, LeDue JM, Matsumoto H, Kiyonari H, Kirino Y, Matsuzaki F, Suzuki T, Murphy TH, Wang YT, Yamamoto T, Craig AM (2016)
Altered Cortical Dynamics and Cognitive Function upon Haploinsufficiency of the Autism-Linked Excitatory Synaptic Suppressor MDGA2
Neuron 91: 1052
Mo X, Tang H, Zeng L, Lu H, Guo L, Ma Z (2016)
[The value of determination of serum cholinesterase levels in judgment of severity and prognosis in patients with severe pneumonia]
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 28: 38
Cheng J, Wang D, Hu S, Jiang H, Lu H, Lei Q, Liu J, Yuan F, Chen R (2014)
The Report of Sustained Low-Efficiency Dialysis (SLED) Treatment in Fifteen Patients of Severe Snakebite
Cell Biochem Biophys 69: 71
Han K, Holder JL, Jr., Schaaf CP, Lu H, Chen H, Kang H, Tang J, Wu Z, Hao S, Cheung SW, Yu P, Sun H, Breman AM, Patel A, Lu HC, Zoghbi HY (2013)
SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties
Nature 503: 72
Lu H, Hu J, Li J, Pang W, Hu Y, Yang H, Li W, Huang C, Zhang M, Jiang Y (2013)
Optimal dose of zinc supplementation for preventing aluminum-induced neurotoxicity in rats
Neural Regen Res 8: 2754
Peng L, Cui JY, Yoo B, Gunewardena SS, Lu H, Klaassen CD, Zhong XB (2013)
RNA-Sequencing Quantification of Hepatic Ontogeny of Phase-I Enzymes in Mice
Drug Metabolism & Disposition: The Biological Fate of Chemicals 41: 2175
Husson SJ, Costa WS, Wabnig S, Stirman JN, Watson JD, Spencer WC, Akerboom J, Looger LL, Treinin M, Miller DM, 3rd, Lu H, Gottschalk A (2012)
Optogenetic analysis of a nociceptor neuron and network reveals ion channels acting downstream of primary sensors
Current Biology 22: 743
Bogdanove AJ, Koebnik R, Lu H, Furutani A, Angiuoli SV, Patil PB, Van Sluys MA, Ryan RP, Meyer DF, Han SW, Aparna G, Rajaram M, Delcher AL, Phillippy AM, Puiu D, Schatz MC, Shumway M, Sommer DD, Trapnell C, Benahmed F, Dimitrov G, Madupu R, Radune D, Sullivan S, Jha G, Ishihara H, Lee SW, Pandey A, Sharma V, Sriariyanun M, Szurek B, Vera-Cruz CM, Dorman KS, Ronald PC, Verdier V, Dow JM, Sonti RV, Tsuge S, Brendel VP, Rabinowicz PD, Leach JE, White FF, Salzberg SL (2011)
Two new complete genome sequences offer insight into host and tissue specificity of plant pathogenic Xanthomonas spp
Journal of Bacteriology 193: 5450
Galron R, Gruber R, Lifshitz V, Lu H, Kirshner M, Ziv N, Wang ZQ, Shiloh Y, Barzilai A, Frenkel D (2011)
Astrocyte dysfunction associated with cerebellar attrition in a Nijmegen breakage syndrome animal model
Journal of Molecular Neuroscience 45: 202
Lu H, Zhou J, Xiong S, Zhao S (2010)
Effects of low-intensity microwave radiation on Tribolium castaneum physiological and biochemical characteristics and survival
J Insect Physiol 56: 1356
Guettier JM, Gautam D, Scarselli M, Ruiz de Azua I, Li JH, Rosemond E, Ma X, Gonzalez FJ, Armbruster BN, Lu H, Roth BL, Wess J (2009)
A chemical-genetic approach to study G protein regulation of beta cell function in vivo
Proc Natl Acad Sci U S A 106: 19197
Xiong Z, Jiang Y, Qi D, Lu H, Yang F, Yang J, Chen L, Sun L, Xu X, Xue Y, Zhu Y, Jin Q (2009)
Complete genome sequence of the extremophilic Bacillus cereus strain Q1 with industrial applications
Journal of Bacteriology 191: 1120
Jin QH, He HY, Shi YF, Lu H, Zhang XJ (2004)
Overexpression of acetylcholinesterase inhibited cell proliferation and promoted apoptosis in NRK cells
Acta Pharmacol Sin 25: 1013
Yin Y, Lu H, Khosla C, Cane DE (2003)
Expression and kinetic analysis of the substrate specificity of modules 5 and 6 of the picromycin/methymycin polyketide synthase
Journal of the American Chemical Society 125: 5671
Tsai SC, Lu H, Cane DE, Khosla C, Stroud RM (2002)
Insights into channel architecture and substrate specificity from crystal structures of two macrocycle-forming thioesterases of modular polyketide synthases
Biochemistry 41: 12598
Zheng X, Feng Y, Jiang X, Lu H, Wan Y, Fang YQ, Li YP, Huang XY, Li ZL, Fu WZ, Wang XH, Lin YZ, Zhang Z (1997)
[Environmental pollution, human exposure and its health effect of sodium pentachlorophenate in schistosomiasis prevalent area]
Wei Sheng Yan Jiu 26: 24
Song Q, Khanna KK, Lu H, Lavin MF (1993)
Cloning and characterization of a human protein phosphatase 1-encoding cDNA
Gene 129: 291