Won SJ, Cheung See Kit M, Martin BR (2018)
Protein depalmitoylases
Crit Rev Biochem Mol Biol 53: 83

Won SJ, Martin BR (2018)
Temporal Profiling Establishes a Dynamic S-Palmitoylation Cycle
ACS Chemical Biology 13: 1560

Hernandez JL, Davda D, Cheung See Kit M, Majmudar JD, Won SJ, Gang M, Pasupuleti SC, Choi AI, Bartkowiak CM, Martin BR (2017)
APT2 Inhibition Restores Scribble Localization and S-Palmitoylation in Snail-Transformed Cells
Cell Chemical Biology 24: 87

Won SJ, Eschweiler JD, Majmudar JD, Chong FS, Hwang SY, Ruotolo BT, Martin BR (2017)
Affinity-Based Selectivity Profiling of an In-Class Selective Competitive Inhibitor of Acyl Protein Thioesterase 2
ACS Med Chem Lett 8: 215

Davda D, Martin BR (2014)
Human lysosomal acid lipase inhibitor lalistat impairs Mycobacterium tuberculosis growth by targeting bacterial hydrolases
Medchemcomm 7: 1797

Won SJ, Davda D, Labby KJ, Hwang SY, Pricer R, Majmudar JD, Armacost KA, Rodriguez LA, Rodriguez CL, Chong FS, Torossian KA, Palakurthi J, Hur ES, Meagher JL, Brooks CL, 3rd, Stuckey JA, Martin BR (2016)
Molecular Mechanism for Isoform-Selective Inhibition of Acyl Protein Thioesterases 1 and 2 (APT1 and APT2)
ACS Chemical Biology 11: 3374

Foe IT, Child MA, Majmudar JD, Krishnamurthy S, van der Linden WA, Ward GE, Martin BR, Bogyo M (2015)
Global Analysis of Palmitoylated Proteins in Toxoplasma gondii
Cell Host Microbe 18: 501

Xu H, Majmudar JD, Davda D, Ghanakota P, Kim KH, Carlson HA, Showalter HD, Martin BR, Amidon GL (2015)
Substrate-Competitive Activity-Based Profiling of Ester Prodrug Activating Enzymes
Mol Pharm 12: 3399

Davda D, Martin BR (2014)
Acyl protein thioesterase inhibitors as probes of dynamic S-palmitoylation
Medchemcomm 5: 268

Jia L, Chisari M, Maktabi MH, Sobieski C, Zhou H, Konopko AM, Martin BR, Mennerick SJ, Blumer KJ (2014)
A mechanism regulating G protein-coupled receptor signaling that requires cycles of protein palmitoylation and depalmitoylation
Journal of Biological Chemistry 289: 6249

Adibekian A, Martin BR, Chang JW, Hsu KL, Tsuboi K, Bachovchin DA, Speers AE, Brown SJ, Spicer T, Fernandez-Vega V, Ferguson J, Cravatt BF, Hodder P, Rosen H (2013)
Characterization of a Selective, Reversible Inhibitor of Lysophospholipase 1 (LYPLA1)
Probe Report

Adibekian A, Martin BR, Chang JW, Hsu KL, Tsuboi K, Bachovchin DA, Speers AE, Brown SJ, Spicer T, Fernandez-Vega V, Ferguson J, Cravatt BF, Hodder P, Rosen H (2013)
Characterization of a Selective, Reversible Inhibitor of Lysophospholipase 2 (LYPLA2)
Probe Report

Adibekian A, Martin BR, Chang JW, Hsu KL, Tsuboi K, Bachovchin DA, Speers AE, Brown SJ, Spicer T, Fernandez-Vega V, Ferguson J, Hodder PS, Rosen H, Cravatt BF (2012)
Confirming target engagement for reversible inhibitors in vivo by kinetically tuned activity-based probes
J Am Chem Soc 134: 10345

Martin BR, Wang C, Adibekian A, Tully SE, Cravatt BF (2012)
Global profiling of dynamic protein palmitoylation
Nat Methods 9: 84

Adibekian A, Martin BR, Wang C, Hsu KL, Bachovchin DA, Niessen S, Hoover H, Cravatt BF (2011)
Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors
Nat Chemical Biology 7: 469

Adibekian A, Martin BR, Speers AE, Brown SJ, Spicer T, Fernandez-Vega V, Ferguson J, Cravatt BF, Hodder P, Rosen H (2011)
Optimization and characterization of a triazole urea dual inhibitor for lysophospholipase 1 (LYPLA1) and lysophospholipase 2 (LYPLA2)
Probe Report

Carroll FI, Ma W, Deng L, Navarro HA, Damaj MI, Martin BR (2010)
Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 3'-(substituted phenyl)epibatidine analogues. Nicotinic partial agonists
Journal of Natural Products 73: 306

Jackson KJ, Kota DH, Martin BR, Damaj MI (2009)
The role of various nicotinic receptor subunits and factors influencing nicotine conditioned place aversion
Neuropharmacology 56: 970

Jackson KJ, Walters CL, Miles MF, Martin BR, Damaj MI (2009)
Characterization of pharmacological and behavioral differences to nicotine in C57Bl/6 and DBA/2 mice
Neuropharmacology 57: 347

Martin BR, Cravatt BF (2009)
Large-scale profiling of protein palmitoylation in mammalian cells
Nat Methods 6: 135

Abdrakhmanova GR, Carroll FI, Damaj MI, Martin BR (2008)
3'-Fluoro substitution in the pyridine ring of epibatidine improves selectivity and efficacy for alpha4beta2 versus alpha3beta4 nAChRs
Neuropharmacology 55: 1287

Ivy Carroll F, Yokota Y, Ma W, Lee JR, Brieaddy LE, Burgess JP, Navarro HA, Damaj MI, Martin BR (2008)
Synthesis, nicotinic acetylcholine receptor binding, and pharmacological properties of 3'-(substituted phenyl)deschloroepibatidine analogs
Bioorganic & Medicinal Chemistry 16: 746

Jackson KJ, Martin BR, Changeux JP, Damaj MI (2008)
Differential role of nicotinic acetylcholine receptor subunits in physical and affective nicotine withdrawal signs
Journal of Pharmacology & Experimental Therapeutics 325: 302

Kota D, Martin BR, Damaj MI (2008)
Age-dependent differences in nicotine reward and withdrawal in female mice
Psychopharmacology (Berl) 198: 201

Merritt LL, Martin BR, Walters C, Lichtman AH, Damaj MI (2008)
The endogenous cannabinoid system modulates nicotine reward and dependence
Journal of Pharmacology & Experimental Therapeutics 326: 483

Carroll FI, Robinson TP, Brieaddy LE, Atkinson RN, Mascarella SW, Damaj MI, Martin BR, Navarro HA (2007)
Synthesis and nicotinic acetylcholine receptor binding properties of bridged and fused ring analogues of epibatidine
Journal of Medicinal Chemistry 50: 6383

Chen X, Che Y, Zhang L, Putman AH, Damaj MI, Martin BR, Kendler KS, Miles MF (2007)
RhoA, encoding a Rho GTPase, is associated with smoking initiation
Genes Brain Behav 6: 689

Damaj MI, Fonck C, Marks MJ, Deshpande P, Labarca C, Lester HA, Collins AC, Martin BR (2007)
Genetic approaches identify differential roles for alpha4beta2* nicotinic receptors in acute models of antinociception in mice
Journal of Pharmacology & Experimental Therapeutics 321: 1161

Damaj MI, Siu EC, Sellers EM, Tyndale RF, Martin BR (2007)
Inhibition of nicotine metabolism by methoxysalen: Pharmacokinetic and pharmacological studies in mice
Journal of Pharmacology & Experimental Therapeutics 320: 250

Ivy Carroll F, Ma W, Navarro HA, Abraham P, Wolckenhauer SA, Damaj MI, Martin BR (2007)
Synthesis, nicotinic acetylcholine receptor binding, antinociceptive and seizure properties of methyllycaconitine analogs
Bioorganic & Medicinal Chemistry 15: 678

Kota D, Martin BR, Robinson SE, Damaj MI (2007)
Nicotine dependence and reward differ between adolescent and adult male mice
Journal of Pharmacology & Experimental Therapeutics 322: 399

Naidu PS, Varvel SA, Ahn K, Cravatt BF, Martin BR, Lichtman AH (2007)
Evaluation of fatty acid amide hydrolase inhibition in murine models of emotionality
Psychopharmacology (Berl) 192: 61

Wise LE, Shelton CC, Cravatt BF, Martin BR, Lichtman AH (2007)
Assessment of anandamide's pharmacological effects in mice deficient of both fatty acid amide hydrolase and cannabinoid CB1 receptors
European Journal of Pharmacology 557: 44

Abdrakhmanova GR, Damaj MI, Carroll FI, Martin BR (2006)
2-Fluoro-3-(4-nitro-phenyl)deschloroepibatidine is a novel potent competitive antagonist of human neuronal alpha4beta2 nAChRs
Molecular Pharmacology 69: 1945

Carroll FI, Hu X, Navarro HA, Deschamps J, Abdrakhmanova GR, Damaj MI, Martin BR (2006)
Synthesis and pharmacological characterization of nicotinic acetylcholine receptor properties of (+)- and (-)-pyrido-[3,4-b]homotropanes
Journal of Medicinal Chemistry 49: 3244

Grabus SD, Martin BR, Brown SE, Damaj MI (2006)
Nicotine place preference in the mouse: influences of prior handling, dose and strain and attenuation by nicotinic receptor antagonists
Psychopharmacology (Berl) 184: 456

Carroll FI, Brieaddy LE, Navarro HA, Damaj MI, Martin BR (2005)
Synthesis and pharmacological characterization of exo-2-(2'-chloro-5-pyridinyl)-7-(endo and exo)-aminobicyclo[2.2.1]heptanes as novel epibatidine analogues
Journal of Medicinal Chemistry 48: 7491

Carroll FI, Ma W, Yokota Y, Lee JR, Brieaddy LE, Navarro HA, Damaj MI, Martin BR (2005)
Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 3'-substituted deschloroepibatidine analogues. Novel nicotinic antagonists
Journal of Medicinal Chemistry 48: 1221

Damaj MI, Flood P, Ho KK, May EL, Martin BR (2005)
Effect of dextrometorphan and dextrorphan on nicotine and neuronal nicotinic receptors: in vitro and in vivo selectivity
Journal of Pharmacology & Experimental Therapeutics 312: 780

Damaj MI, Wiley JL, Martin BR, Papke RL (2005)
In vivo characterization of a novel inhibitor of CNS nicotinic receptors
European Journal of Pharmacology 521: 43

Grabus SD, Martin BR, Batman AM, Tyndale RF, Sellers E, Damaj MI (2005)
Nicotine physical dependence and tolerance in the mouse following chronic oral administration
Psychopharmacology (Berl) 178: 183

Vandevoorde S, Saha B, Mahadevan A, Razdan RK, Pertwee RG, Martin BR, Fowler CJ (2005)
Influence of the degree of unsaturation of the acyl side chain upon the interaction of analogues of 1-arachidonoylglycerol with monoacylglycerol lipase and fatty acid amide hydrolase
Biochemical & Biophysical Research Communications 337: 104

Carroll FI, Ware R, Brieaddy LE, Navarro HA, Damaj MI, Martin BR (2004)
Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2'-fluoro-3'-(substituted phenyl)deschloroepibatidine analogues. Novel nicotinic antagonist
Journal of Medicinal Chemistry 47: 4588

Damaj MI, Carroll FI, Eaton JB, Navarro HA, Blough BE, Mirza S, Lukas RJ, Martin BR (2004)
Enantioselective effects of hydroxy metabolites of bupropion on behavior and on function of monoamine transporters and nicotinic receptors
Molecular Pharmacology 66: 675

Damaj MI, Hunter RG, Martin BR, Kuhar MJ (2004)
Intrathecal CART (55-102) enhances the spinal analgesic actions of morphine in mice
Brain Research 1024: 146

Dogruer D, Lee M, Dukat M, Damaj MI, Martin BR, Glennon RA (2004)
3-(4-Aminobutyn-1-yl)pyridines: binding at alpha 4 beta 2 nicotinic cholinergic receptors
Bioorganic & Medicinal Chemistry Lett 14: 523

Dukat M, Taroua M, Dahdouh A, Siripurapu U, Damaj MI, Martin BR, Glennon RA (2004)
(+/-)8-Amino-5,6,7,8-tetrahydroisoquinolines as novel antinociceptive agents
Bioorganic & Medicinal Chemistry Lett 14: 3651

Ghafouri N, Tiger G, Razdan RK, Mahadevan A, Pertwee RG, Martin BR, Fowler CJ (2004)
Inhibition of monoacylglycerol lipase and fatty acid amide hydrolase by analogues of 2-arachidonoylglycerol
British Journal of Pharmacology 143: 774

Damaj MI, Kao W, Martin BR (2003)
Characterization of spontaneous and precipitated nicotine withdrawal in the mouse
Journal of Pharmacology & Experimental Therapeutics 307: 526

Damaj MI, Martin BR, Kuhar MJ (2003)
Antinociceptive effects of supraspinal rat cart (55-102) peptide in mice
Brain Research 983: 233

Ferretti G, Dukat M, Giannella M, Piergentili A, Pigini M, Quaglia W, Damaj MI, Martin BR, Glennon RA (2003)
Binding of nicotine and homoazanicotine analogues at neuronal nicotinic acetylcholinergic (nACh) receptors
Bioorganic & Medicinal Chemistry Lett 13: 733

Carroll FI, Lee JR, Navarro HA, Ma W, Brieaddy LE, Abraham P, Damaj MI, Martin BR (2002)
Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2',3'-disubstituted 5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes: epibatidine analogues
Journal of Medicinal Chemistry 45: 4755

Dukat M, Damaj MI, Young R, Vann R, Collins AC, Marks MJ, Martin BR, Glennon RA (2002)
Functional diversity among 5-substituted nicotine analogs; in vitro and in vivo investigations
European Journal of Pharmacology 435: 171

Dukat M, El-Zahabi M, Ferretti G, Damaj MI, Martin BR, Young R, Glennon RA (2002)
(-)6-n-Propylnicotine antagonizes the antinociceptive effects of (-)nicotine
Bioorganic & Medicinal Chemistry Lett 12: 3005

Ferretti G, Dukat M, Giannella M, Piergentili A, Pigini M, Quaglia W, Damaj MI, Martin BR, Glennon RA (2002)
Homoazanicotine: a structure-affinity study for nicotinic acetylcholine (nACh) receptor binding
Journal of Medicinal Chemistry 45: 4724

Wiley JL, Lavecchia KL, Martin BR, Damaj MI (2002)
Nicotine-like discriminative stimulus effects of bupropion in rats
Experimental & Clinical Psychopharmacology 10: 129

Carroll FI, Lee JR, Navarro HA, Brieaddy LE, Abraham P, Damaj MI, Martin BR (2001)
Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2'-substituted-3'-phenyl-5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes. Novel nicotinic antagonist
Journal of Medicinal Chemistry 44: 4039

Carroll FI, Liang F, Navarro HA, Brieaddy LE, Abraham P, Damaj MI, Martin BR (2001)
Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2'-substituted 5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes. Epibatidine analogues
Journal of Medicinal Chemistry 44: 2229

Cravatt BF, Demarest K, Patricelli MP, Bracey MH, Giang DK, Martin BR, Lichtman AH (2001)
Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase
Proc Natl Acad Sci U S A 98: 9371

Di Marzo V, Bisogno T, De Petrocellis L, Brandi I, Jefferson RG, Winckler RL, Davis JB, Dasse O, Mahadevan A, Razdan RK, Martin BR (2001)
Highly selective CB(1) cannabinoid receptor ligands and novel CB(1)/VR(1) vanilloid receptor hybrid ligands
Biochemical & Biophysical Research Communications 281: 444

Damaj MI, Meyer EM, Martin BR (2000)
The antinociceptive effects of alpha7 nicotinic agonists in an acute pain model
Neuropharmacology 39: 2785

Ferretti G, Dukat M, Giannella M, Piergentili A, Pigini M, Quaglia W, Damaj MI, Martin BR, Glennon RA (2000)
Chain-lengthened and imidazoline analogues of nicotine
Bioorganic & Medicinal Chemistry Lett 10: 2665

Martin BR, Beletskaya I, Patrick G, Jefferson R, Winckler R, Deutsch DG, Di Marzo V, Dasse O, Mahadevan A, Razdan RK (2000)
Cannabinoid properties of methylfluorophosphonate analogs
Journal of Pharmacology & Experimental Therapeutics 294: 1209

Narahashi T, Fenster CP, Quick MW, Lester RA, Marszalec W, Aistrup GL, Sattelle DB, Martin BR, Levin ED (2000)
Symposium overview: mechanism of action of nicotine on neuronal acetylcholine receptors, from molecule to behavior
Toxicol Sci 57: 193

Slemmer JE, Martin BR, Damaj MI (2000)
Bupropion is a nicotinic antagonist
Journal of Pharmacology & Experimental Therapeutics 295: 321

Damaj MI, Glassco W, Aceto MD, Martin BR (1999)
Antinociceptive and pharmacological effects of metanicotine, a selective nicotinic agonist
Journal of Pharmacology & Experimental Therapeutics 291: 390

Damaj MI, Glassco W, Dukat M, Martin BR (1999)
Pharmacological characterization of nicotine-induced seizures in mice
Journal of Pharmacology & Experimental Therapeutics 291: 1284

Damaj MI, Slemmer JE, Carroll FI, Martin BR (1999)
Pharmacological characterization of nicotine's interaction with cocaine and cocaine analogs
Journal of Pharmacology & Experimental Therapeutics 289: 1229

Damaj MI, Fei-Yin M, Dukat M, Glassco W, Glennon RA, Martin BR (1998)
Antinociceptive responses to nicotinic acetylcholine receptor ligands after systemic and intrathecal administration in mice
Journal of Pharmacology & Experimental Therapeutics 284: 1058

Damaj MI, Glassco W, Marks MJ, Slobe B, James JR, May EL, Rosecrans JA, Collins AC, Martin BR (1997)
Pharmacological investigation of (+)- and (-)-cis-2,3,3a,4,5,9b-hexahydro-1-methyl-1H-pyrrolo-[3,2-h]isoq uinoline, a bridged-nicotine analog
Journal of Pharmacology & Experimental Therapeutics 282: 1425

Damaj MI, Patrick GS, Creasy KR, Martin BR (1997)
Pharmacology of lobeline, a nicotinic receptor ligand
Journal of Pharmacology & Experimental Therapeutics 282: 410

Damaj MI, Martin BR (1996)
Tolerance to the antinociceptive effect of epibatidine after acute and chronic administration in mice
European Journal of Pharmacology 300: 51

Damaj MI, Welch SP, Martin BR (1996)
Characterization and modulation of acute tolerance to nicotine in mice
Journal of Pharmacology & Experimental Therapeutics 277: 454

Damaj MI, Creasy KR, Welch SP, Rosecrans JA, Aceto MD, Martin BR (1995)
Comparative pharmacology of nicotine and ABT-418, a new nicotinic agonist
Psychopharmacology (Berl) 120: 483

Damaj MI, Welch SP, Martin BR (1995)
In vivo pharmacological effects of dihydro-beta-erythroidine, a nicotinic antagonist, in mice
Psychopharmacology (Berl) 117: 67

Damaj MI, Creasy KR, Grove AD, Rosecrans JA, Martin BR (1994)
Pharmacological effects of epibatidine optical enantiomers
Brain Research 664: 34

Damaj MI, Glennon RA, Martin BR (1994)
Involvement of the serotonergic system in the hypoactive and antinociceptive effects of nicotine in mice
Brain Research Bulletin 33: 199

Damaj MI, Welch SP, Martin BR (1994)
Nicotine-induced antinociception in mice: role of G-proteins and adenylate cyclase
Pharmacol Biochem Behav 48: 37

Damaj MI, Martin BR (1993)
Calcium agonists and antagonists of the dihydropyridine type: effect on nicotine-induced antinociception and hypomotility
Drug Alcohol Depend 32: 73

Damaj MI, Martin BR (1993)
Is the dopaminergic system involved in the central effects of nicotine in mice?
Psychopharmacology (Berl) 111: 106

Damaj MI, Welch SP, Martin BR (1993)
Involvement of calcium and L-type channels in nicotine-induced antinociception
Journal of Pharmacology & Experimental Therapeutics 266: 1330