Mukhametgalieva AR, Nemtarev AV, Sykaev VV, Pashirova TN, Masson P (2023) <br />Activation/Inhibition of Cholinesterases by Excess Substrate: Interpretation of the Phenomenological b Factor in Steady-State Rate Equation<br /><i>Int J Mol Sci</i> <b>24</b>: <br /><br />Masson P, Lushchekina S (2022) <br />Conformational Stability and Denaturation Processes of Proteins Investigated by Electrophoresis under Extreme Conditions<br /><i>Molecules</i> <b>27</b>: <br /><br />Mukhametgalieva AR, Lushchekina SV, Aglyamova AR, Masson P (2021) <br />Steady-state kinetic analysis of human cholinesterases over wide concentration ranges of competing substrates<br /><i>Biochimica & Biophysica Acta Proteins Proteom</i> <br /><br />Pashirova TN, Bogdanov A, Masson P (2021) <br />Therapeutic nanoreactors for detoxification of xenobiotics: Concepts, challenges and biotechnological trends with special emphasis to organophosphate bioscavenging<br /><i>Chemico-Biological Interactions</i> <br /><br />Poirier L, Jacquet P, Plener L, Masson P, Daude D, Chabriere E (2021) <br />Organophosphorus poisoning in animals and enzymatic antidotes<br /><i>Environ Sci Pollut Res Int</i> <b>28</b>: 25081<br /><br />Zueva IV, Lenina OA, Kayumova RM, Petrov KA, Masson P (2021) <br />Protective effects of m-(tert-butyl) trifluoroacetophenone, a transition state analogue of acetylcholine, against paraoxon toxicity and memory impairments<br /><i>Chemico-Biological Interactions</i> <b>345</b>: 109558<br /><br />Zueva I, Lushchekina S, Shulnikova P, Lenina O, Petrov K, Molochkina E, Masson P (2021) <br />alpha-tocopherol, a slow-binding inhibitor of acetylcholinesterase<br /><i>Chemico-Biological Interactions</i> <br /><br />Lenina OA, Zueva IV, Zobov VV, Semenov VE, Masson P, Petrov KA (2020) <br />Slow-binding reversible inhibitor of acetylcholinesterase with long-lasting action for prophylaxis of organophosphate poisoning<br /><i>Sci Rep</i> <b>10</b>: 16611<br /><br />Lushchekina SV, Masson P (2020) <br />Slow-binding inhibitors of acetylcholinesterase of medical interest<br /><i>Neuropharmacology</i> <br /><br />Lushchekina SV, Inidjel G, Martinez N, Masson P, Trovaslet-Leroy M, Nachon F, Koza MM, Seydel T, Peters J (2020) <br />Impact of Sucrose as Osmolyte on Molecular Dynamics of Mouse Acetylcholinesterase<br /><i>Biomolecules</i> <b>10</b>: <br /><br />Zueva IV, Lushchekina SV, Daude D, Chabriere E, Masson P (2020) <br />Steady-State Kinetics of Enzyme-Catalyzed Hydrolysis of Echothiophate, a P-S Bonded Organophosphorus as Monitored by Spectrofluorimetry<br /><i>Molecules</i> <b>25</b>: <br /><br />Zueva IV, Lushchekina SV, Pottie IR, Darvesh S, Masson P (2020) <br />1-(3-Tert-Butylphenyl)-2,2,2-Trifluoroethanone as a Potent Transition-State Analogue Slow-Binding Inhibitor of Human Acetylcholinesterase: Kinetic, MD and QM/MM Studies<br /><i>Biomolecules</i> <b>10</b>: <br /><br />Grigorenko BL, Novichkova DA, Lushchekina SV, Zueva IV, Schopfer LM, Nemukhin AV, Varfolomeev SD, Lockridge O, Masson P (2019) <br />Computer-designed active human butyrylcholinesterase double mutant with a new catalytic triad<br /><i>Chemico-Biological Interactions</i> <b>306</b>: 138<br /><br />Kangur L, Timpmann K, Zeller D, Masson P, Peters J, Freiberg A (2019) <br />Structural Stability of Human Butyrylcholinesterase under High Hydrostatic Pressure<br /><i>Biochimica & Biophysica Acta Proteins Proteom</i> <b>1867</b>: 107<br /><br />Mukhametgalieva AR, Zueva IV, Aglyamova AR, Lushchekina SV, Masson P (2019) <br />A new sensitive spectrofluorimetric method for measurement of activity and kinetic study of cholinesterases<br /><i>Biochimica & Biophysica Acta Proteins Proteom</i> <br /><br />Mukhametgalieva AR, Aglyamova AR, Lushchekina SV, Golicnik M, Masson P (2019) <br />Time-course of human cholinesterases-catalyzed competing substrate kinetics<br /><i>Chemico-Biological Interactions</i> <b>310</b>: 108702<br /><br />Novichkova DA, Lushchekina SV, Dym O, Masson P, Silman I, Sussman JL (2019) <br />The four-helix bundle in cholinesterase dimers: Structural and energetic determinants of stability<br /><i>Chemico-Biological Interactions</i> <b>309</b>: 108699<br /><br />Semenov VE, Zueva IV, Lushchekina SV, Lenina OA, Gubaidullina LM, Saifina LF, Shulaeva MM, Kayumova RM, Saifina AF, Gubaidullin AT, Kondrashova SA, Latypov SK, Masson P, Petrov KA (2019) <br />6-Methyluracil derivatives as peripheral site ligand-hydroxamic acid conjugates: Reactivation for paraoxon-inhibited acetylcholinesterase<br /><i>Eur Journal of Medicinal Chemistry</i> <b>185</b>: 111787<br /><br />Zueva IV, Dias J, Lushchekina SV, Semenov VE, Mukhamedyarov MA, Pashirova TN, Babaev VM, Nachon F, Petrova N, Nurullin LF, Zakharova LY, Ilyin VI, Masson P, Petrov KA (2019) <br />New evidence for dual binding site inhibitors of acetylcholinesterase as improved drugs for treatment of Alzheimer's disease<br /><i>Neuropharmacology</i> <b>155</b>: 131<br /><br />Boyko KM, Baymukhametov TN, Chesnokov YM, Hons M, Lushchekina SV, Konarev PV, Lipkin AV, Vasiliev AL, Masson P, Popov VO, Kovalchuk MV (2018) <br />3D structure of the natural tetrameric form of human butyrylcholinesterase as revealed by cryoEM, SAXS and MD<br /><i>Biochimie</i> <b>156</b>: 196<br /><br />Lockridge O, David E, Schopfer LM, Masson P, Brazzolotto X, Nachon F (2018) <br />Purification of recombinant human butyrylcholinesterase on Hupresin(R)<br /><i>Journal of Chromatography B Analyt Technol Biomed Life Sciences</i> <b>1102-1103</b>: 109<br /><br />Lushchekina SV, Schopfer LM, Grigorenko BL, Nemukhin AV, Varfolomeev SD, Lockridge O, Masson P (2018) <br />Optimization of Cholinesterase-Based Catalytic Bioscavengers Against Organophosphorus Agents<br /><i>Front Pharmacol</i> <b>9</b>: 211<br /><br />Lushchekina S, Masson P (2018) <br />Catalytic bioscavengers against organophosphorus agents: mechanistic issues of self-reactivating cholinesterases<br /><i>Toxicology</i> <b>409</b>: 91<br /><br />Pashirova TN, Zueva IV, Petrov KA, Lukashenko SS, Nizameev IR, Kulik NV, Voloshina AD, Almasy L, Kadirov MK, Masson P, Souto EB, Zakharova LY, Sinyashin OG (2018) <br />Mixed cationic liposomes for brain delivery of drugs by the intranasal route: The acetylcholinesterase reactivator 2-PAM as encapsulated drug model<br /><i>Colloids Surf B Biointerfaces</i> <b>171</b>: 358<br /><br />Pashirova TN, Braiki A, Zueva IV, Petrov KA, Babaev VM, Burilova EA, Samarkina DA, Rizvanov IK, Souto EB, Jean L, Renard PY, Masson P, Zakharova LY, Sinyashin OG (2018) <br />Combination delivery of two oxime-loaded lipid nanoparticles: Time-dependent additive action for prolonged rat brain protection<br /><i>J Control Release</i> <b>290</b>: 102<br /><br />Petrov KA, Zueva IV, Kovyazina IV, Sedov I, Lushchekina SV, Kharlamova AD, Lenina O, Koshkin S, Shtyrlin Y, Nikolsky EE, Masson P (2018) <br />C-547, a 6-methyluracil derivative with long-lasting binding and rebinding on acetylcholinesterase: Pharmacokinetic and pharmacodynamic studies<br /><i>Neuropharmacology</i> <b>131</b>: 304<br /><br />Petrov KA, Nikolsky EE, Masson P (2018) <br />Autoregulation of Acetylcholine Release and Micro-Pharmacodynamic Mechanisms at Neuromuscular Junction: Selective Acetylcholinesterase Inhibitors for Therapy of Myasthenic Syndromes<br /><i>Front Pharmacol</i> <b>9</b>: 766<br /><br />Zueva IV, Lushchekina SV, Masson P (2018) <br />Water structure changes in oxime-mediated reactivation process of phosphorylated human acetylcholinesterase<br /><i>Bioscience Reports</i> <b>38</b>: <br /><br />Dafferner AJ, Lushchekina SV, Masson P, Xiao G, Schopfer LM, Lockridge O (2017) <br />Characterization of butyrylcholinesterase in bovine serum<br /><i>Chemico-Biological Interactions</i> <b>266</b>: 17<br /><br />Masson P, Nachon F (2017) <br />Cholinesterase reactivators and bioscavengers for pre- and post-exposure treatments of organophosphorus poisoning<br /><i>Journal of Neurochemistry</i> <b>142 Suppl 2</b>: 26<br /><br />Pashirova TN, Zueva IV, Petrov KA, Babaev VM, Lukashenko SS, Rizvanov IK, Souto EB, Nikolsky EE, Zakharova LY, Masson P, Sinyashin OG (2017) <br />Nanoparticle-Delivered 2-PAM for Rat Brain Protection against Paraoxon Central Toxicity<br /><i>ACS Appl Mater Interfaces</i> <b>9</b>: 16922<br /><br />Schopfer LM, Delacour H, Masson P, Leroy J, Krejci E, Lockridge O (2017) <br />The C5 Variant of the Butyrylcholinesterase Tetramer Includes a Noncovalently Bound 60 kDa Lamellipodin Fragment<br /><i>Molecules</i> <b>22</b>: <br /><br />Terekhov SS, Smirnov IV, Stepanova AV, Bobik TV, Mokrushina YA, Ponomarenko NA, Belogurov AA, Jr., Rubtsova MP, Kartseva OV, Gomzikova MO, Moskovtsev AA, Bukatin AS, Dubina MV, Kostryukova ES, Babenko VV, Vakhitova MT, Manolov AI, Malakhova MV, Kornienko MA, Tyakht AV, Vanyushkina AA, Ilina EN, Masson P, Gabibov AG, Altman S (2017) <br />Microfluidic droplet platform for ultrahigh-throughput single-cell screening of biodiversity<br /><i>Proc Natl Acad Sci U S A</i> <b>114</b>: 2550<br /><br />Terekhov SS, Palikov VA, Palikova YA, Dyachenko IA, Shamborant OG, Smirnov IV, Masson P, Gabibov AG (2017) <br />Application of Tetrameric Recombinant Human Butyrylcholinesterase as a Biopharmaceutical for Amelioration of Symptoms of Acute Organophosphate Poisoning<br /><i>Bulletin of Experimental Biology & Medicine</i> <b>163</b>: 430<br /><br />Elistratova JG, Mustafina AR, Brylev KA, Petrov KA, Shestopalov MA, Mironov YV, Babaev VM, Rizvanov IK, Masson P, Sinyashin OG (2016) <br />Sensing activity of cholinesterases through a luminescence response of the hexarhenium cluster complex [{Re6S8}(OH)6](4.)<br /><i>Analyst</i> <b>141</b>: 4204<br /><br />Jacquet P, Daude D, Bzdrenga J, Masson P, Elias M, Chabriere E (2016) <br />Current and emerging strategies for organophosphate decontamination: special focus on hyperstable enzymes<br /><i>Environ Sci Pollut Res Int</i> <b>23</b>: 8200<br /><br />Kharlamova AD, Lushchekina SV, Petrov KA, Kots ED, Nachon F, Villard-Wandhammer M, Zueva IV, Krejci E, Reznik VS, Zobov VV, Nikolsky EE, Masson P (2016) <br />Slow-binding inhibition of acetylcholinesterase by an alkylammonium derivative of 6-methyluracil: mechanism and possible advantages for myasthenia gravis treatment<br /><i>Biochemical Journal</i> <b>473</b>: 1225<br /><br />Lushchekina SV, Nemukhin AV, Varfolomeev SD, Masson P (2016) <br />Understanding the non-catalytic behavior of human butyrylcholinesterase silent variants: comparison of wild-type enzyme, catalytically active Ala328Cys mutant, and silent Ala328Asp variant<br /><i>Chemico-Biological Interactions</i> <b>259</b>: 223<br /><br />Masson P, Lushchekina SV (2016) <br />Emergence of catalytic bioscavengers against organophosphorus agents<br /><i>Chemico-Biological Interactions</i> <b>259</b>: 319<br /><br />Peng H, Brimijoin S, Hrabovska A, Krejci E, Blake TA, Johnson RC, Masson P, Lockridge O (2016) <br />Monoclonal antibodies to human butyrylcholinesterase reactive with butyrylcholinesterase in animal plasma<br /><i>Chemico-Biological Interactions</i> <b>243</b>: 82<br /><br />Peters J, Martinez N, Trovaslet M, Scannapieco K, Koza MM, Masson P, Nachon F (2016) <br />Dynamics of human acetylcholinesterase bound to non-covalent and covalent inhibitors shedding light on changes to the water network structure<br /><i>Phys Chem Chem Phys</i> <b>18</b>: 12992<br /><br />Lushchekina SV, Delacour H, Lockridge O, Masson P (2015) <br />Human butyrylcholinesterase polymorphism: Molecular modeling<br /><i>Int J Risk Saf Med</i> <b>27 Suppl 1</b>: S80<br /><br />Lushchekina SV, Kots ED, Kharlamova AD, Petrov KA, Masson P (2015) <br />Molecular modeling of mechanism of action of anti-myasthenia gravis slow-binding inhibitor of acetylcholinesterase<br /><i>Int J Risk Saf Med</i> <b>27 Suppl 1</b>: S74<br /><br />Marion J, Trovaslet M, Martinez N, Masson P, Schweins R, Nachon F, Trapp M, Peters J (2015) <br />Pressure-induced molten globule state of human acetylcholinesterase: structural and dynamical changes monitored by neutron scattering<br /><i>Phys Chem Chem Phys</i> <b>17</b>: 3157<br /><br />Mukhametshina AR, Fedorenko SV, Zueva IV, Petrov KA, Masson P, Nizameev IR, Mustafina AR, Sinyashin OG (2015) <br />Luminescent silica nanoparticles for sensing acetylcholinesterase-catalyzed hydrolysis of acetylcholine<br /><i>Biosensors & Bioelectronics</i> <b>77</b>: 871<br /><br />Peng H, Brimijoin S, Hrabovska A, Targosova K, Krejci E, Blake TA, Johnson RC, Masson P, Lockridge O (2015) <br />Comparison of 5 monoclonal antibodies for immunopurification of human butyrylcholinesterase on Dynabeads: K values, binding pairs, and amino acid sequences<br /><i>Chemico-Biological Interactions</i> <b>240</b>: 336<br /><br />Semenov VE, Zueva IV, Mukhamedyarov MA, Lushchekina SV, Kharlamova AD, Petukhova EO, Mikhailov AS, Podyachev SN, Saifina LF, Petrov KA, Minnekhanova OA, Zobov VV, Nikolsky EE, Masson P, Reznik VS (2015) <br />6-Methyluracil Derivatives as Bifunctional Acetylcholinesterase Inhibitors for the Treatment of Alzheimer's Disease<br /><i>ChemMedChem</i> <b>10</b>: 1863<br /><br />Terekhov SS, Smirnov IV, Bobik TV, Shamborant OG, Zenkova MA, Chernolovskaya EL, Gladkikh DV, Murashev AN, Dyachenko IA, Palikov VA, Palikova YA, Knorre VD, Belogurov AA, Jr., Ponomarenko NA, Blackburn GM, Masson P, Gabibov AG (2015) <br />A novel expression cassette delivers efficient production of exclusively tetrameric human butyrylcholinesterase with improved pharmacokinetics for protection against organophosphate poisoning<br /><i>Biochimie</i> <b>118</b>: 51<br /><br />Terekhov SS, Smirnov IV, Shamborant OG, Bobik TV, Ilyushin DG, Murashev AN, Dyachenko IA, Palikov VA, Knorre VD, Belogurov AA, Ponomarenko NA, Kuzina ES, Genkin DD, Masson P, Gabibov AG (2015) <br />Chemical Polysialylation and In Vivo Tetramerization Improve Pharmacokinetic Characteristics of Recombinant Human Butyrylcholinesterase-Based Bioscavengers<br /><i>Acta Naturae</i> <b>7</b>: 136<br /><br />Zueva IV, Semenov VE, Mukhamedyarov MA, Lushchekina SV, Kharlamova AD, Petukhova EO, Mikhailov AS, Podyachev SN, Saifina LF, Petrov KA, Minnekhanova OA, Zobov VV, Nikolsky EE, Masson P, Reznik VS (2015) <br />6-Methyluracil derivatives as acetylcholinesterase inhibitors for treatment of Alzheimer's disease<br /><i>Int J Risk Saf Med</i> <b>27 Suppl 1</b>: S69<br /><br />Delacour H, Lushchekina SV, Mabboux I, Bousquet A, Ceppa F, Schopfer LM, Lockridge O, Masson P (2014) <br />Characterization of a Novel BCHE Silent Allele: Point Mutation (p.Val204Asp) Causes Loss of Activity and Prolonged Apnea with Suxamethonium<br /><i>PLoS ONE</i> <b>9</b>: e101552<br /><br />Delacour H, Lushchekina SV, Mabboux I, Ceppa F, Masson P, Schopfer LM, Lockridge O (2014) <br />Characterization of a novel butyrylcholinesterase point mutation (p.Ala34Val), silent with mivacurium<br /><i>Biochemical Pharmacology</i> <b>92</b>: 476<br /><br />Lushchekina SV, Nemukhin AV, Varfolomeev SD, Masson P (2014) <br />Molecular Modeling Evidence for His438 Flip in the Mechanism of Butyrylcholinesterase Hysteretic Behavior<br /><i>Journal of Molecular Neuroscience</i> <b>52</b>: 434<br /><br />Schopfer LM, Masson P, Lamourette P, Simon S, Lockridge O (2014) <br />Detection of cresyl phosphate-modified butyrylcholinesterase in human plasma for chemical exposure associated with aerotoxic syndrome<br /><i>Analytical Biochemistry</i> <b>461C</b>: 17<br /><br />Trapp M, Tehei M, Trovaslet M, Nachon F, Martinez N, Koza MM, Weik M, Masson P, Peters J (2014) <br />Correlation of the dynamics of native human acetylcholinesterase and its inhibited huperzine A counterpart from sub-picoseconds to nanoseconds<br /><i>J R Soc Interface</i> <b>11</b>: <br /><br />Carletti E, Colletier JP, Schopfer LM, Santoni G, Masson P, Lockridge O, Nachon F, Weik M (2013) <br />Inhibition pathways of the potent organophosphate CBDP with cholinesterases revealed by X-ray crystallographic snapshots and mass spectrometry<br /><i>Chemical Research in Toxicology</i> <b>26</b>: 280<br /><br />Ilyushin DG, Smirnov IV, Belogurov AA, Jr., Dyachenko IA, Zharmukhamedova T, Novozhilova TI, Bychikhin EA, Serebryakova MV, Kharybin ON, Murashev AN, Anikienko KA, Nikolaev EN, Ponomarenko NA, Genkin DD, Blackburn GM, Masson P, Gabibov AG (2013) <br />Chemical polysialylation of human recombinant butyrylcholinesterase delivers a long-acting bioscavenger for nerve agents in vivo<br /><i>Proc Natl Acad Sci U S A</i> <b>110</b>: 1243<br /><br />Ilyushin DG, Haertley OM, Bobik TV, Shamborant OG, Surina EA, Knorre VD, Masson P, Smirnov IV, Gabibov AG, Ponomarenko NA (2013) <br />Recombinant human butyrylcholinesterase as a new-age bioscavenger drug: development of the expression system<br /><i>Acta Naturae</i> <b>5</b>: 73<br /><br />Jiang W, Cashman JR, Nachon F, Masson P, Schopfer LM, Lockridge O (2013) <br />Mass spectrometry method to identify aging pathways of Sp- and Rp-tabun adducts on human butyrylcholinesterase based on the acid labile P-N bond<br /><i>Toxicol Sci</i> <b>132</b>: 390<br /><br />Jiang W, Murashko EA, Dubrovskii YA, Podolskaya EP, Babakov VN, Mikler J, Nachon F, Masson P, Schopfer LM, Lockridge O (2013) <br />Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry of titanium oxide-enriched peptides for detection of aged organophosphorus adducts on human butyrylcholinesterase<br /><i>Analytical Biochemistry</i> <b>439</b>: 132<br /><br />Jiang W, Dubrovskii YA, Podolskaya EP, Murashko EA, Babakov VN, Nachon F, Masson P, Schopfer LM, Lockridge O (2013) <br />PHOS-Select Iron Affinity Beads Enrich Peptides for the Detection of Organophosphorus Adducts on Albumin<br /><i>Chemical Research in Toxicology</i> <b>26</b>: 1917<br /><br />Li B, Duysen EG, Froment MT, Masson P, Nachon F, Jiang W, Schopfer LM, Thiele GM, Klassen LW, Cashman JR, Williams GR, Lockridge O (2013) <br />Polyclonal antibody to soman-tyrosine<br /><i>Chemical Research in Toxicology</i> <b>26</b>: 584<br /><br />Lushchekina SV, Masson P, Rosenberry TL (2013) <br />This special Issue of Chemico-Biological Interactions comprises 70 manuscripts from lectures and short talks given at the 11th International Meeting on Cholinesterases. Preface<br /><i>Chemico-Biological Interactions</i> <b>203</b>: 1<br /><br />Masson P, Lushchekina SV, Schopfer LM, Lockridge O (2013) <br />Effects of viscosity and osmotic stress on the reaction of human butyrylcholinesterase with cresyl saligenin phosphate, a toxicant related to aerotoxic syndrome: kinetic and molecular dynamics studies<br /><i>Biochemical Journal</i> <b>454</b>: 387<br /><br />Nachon F, Brazzolotto X, Trovaslet M, Masson P (2013) <br />Progress in the development of enzyme-based nerve agent bioscavengers<br /><i>Chemico-Biological Interactions</i> <b>206</b>: 536<br /><br />Rozengart EV, Basova NE, Moralev SN, Lushchekina SV, Masson P, Varfolomeev SD (2013) <br />Research on cholinesterases in the Soviet Union and Russia: a historical perspective<br /><i>Chemico-Biological Interactions</i> <b>203</b>: 3<br /><br />Smirnov IV, Belogurov AA, Jr., Friboulet A, Masson P, Gabibov AG, Renard PY (2013) <br />Strategies for the selection of catalytic antibodies against organophosphorus nerve agents<br /><i>Chemico-Biological Interactions</i> <b>203</b>: 196<br /><br />Trovaslet M, Trapp M, Weik M, Nachon F, Masson P, Tehei M, Peters J (2013) <br />Relation between dynamics, activity and thermal stability within the cholinesterase family<br /><i>Chemico-Biological Interactions</i> <b>203</b>: 14<br /><br />Duysen EG, Cashman JR, Schopfer LM, Nachon F, Masson P, Lockridge O (2012) <br />Differential sensitivity of plasma carboxylesterase-null mice to parathion, chlorpyrifos and chlorpyrifos oxon, but not to diazinon, dichlorvos, diisopropylfluorophosphate, cresyl saligenin phosphate, cyclosarin thiocholine, tabun thiocholine, and carbofuran<br /><i>Chemico-Biological Interactions</i> <b>195</b>: 189<br /><br />Masson P (2012) <br />Time-dependent kinetic complexities in cholinesterase-catalyzed reactions<br /><i>Biochemistry (Mosc)</i> <b>77</b>: 1147<br /><br />Peters J, Trovaslet M, Trapp M, Nachon F, Hill F, Royer E, Gabel F, van Eijck L, Masson P, Tehei M (2012) <br />Activity and molecular dynamics relationship within the family of human cholinesterases<br /><i>Phys Chem Chem Phys</i> <b>14</b>: 6764<br /><br />Rosenbaum E, Gabel F, Dura MA, Finet S, Clery-Barraud C, Masson P, Franzetti B (2012) <br />Effects of hydrostatic pressure on the quaternary structure and enzymatic activity of a large peptidase complex from Pyrococcus horikoshii<br /><i>Archives of Biochemistry & Biophysics</i> <b>517</b>: 104<br /><br />Trapp M, Trovaslet M, Nachon F, Koza MM, van Eijck L, Hill F, Weik M, Masson P, Tehei M, Peters J (2012) <br />Energy landscapes of human acetylcholinesterase and its huperzine a-inhibited counterpart<br /><i>J Phys Chem B</i> <b>116</b>: 14744<br /><br />Carletti E, Schopfer LM, Colletier JP, Froment MT, Nachon F, Weik M, Lockridge O, Masson P (2011) <br />Reaction of cresyl saligenin phosphate, the organophosphorus agent implicated in aerotoxic syndrome, with human cholinesterases: mechanistic studies employing kinetics, mass spectrometry, and X-ray structure analysis<br /><i>Chemical Research in Toxicology</i> <b>24</b>: 797<br /><br />Liyasova M, Li B, Schopfer LM, Nachon F, Masson P, Furlong CE, Lockridge O (2011) <br />Exposure to tri-o-cresyl phosphate detected in jet airplane passengers<br /><i>Toxicol Appl Pharmacol</i> <b>256</b>: 337<br /><br />Masson P (2011) <br />Evolution of and perspectives on therapeutic approaches to nerve agent poisoning<br /><i>Toxicol Lett</i> <b>206</b>: 5<br /><br />Nachon F, Carletti E, Wandhammer M, Nicolet Y, Schopfer LM, Masson P, Lockridge O (2011) <br />X-ray crystallographic snapshots of reaction intermediates in the G117H mutant of human butyrylcholinesterase, a nerve agent target engineered into a catalytic bioscavenger<br /><i>Biochemical Journal</i> <b>434</b>: 73<br /><br />Smirnov IV, Carletti E, Kurkova I, Nachon F, Nicolet Y, Mitkevich VA, Debat H, Avalle B, Belogurov AA, Jr., Kuznetsov N, Reshetnyak A, Masson P, Tonevitsky AG, Ponomarenko NA, Makarov AA, Friboulet A, Tramontano A, Gabibov AG (2011) <br />Reactibodies generated by kinetic selection couple chemical reactivity with favorable protein dynamics<br /><i>Proc Natl Acad Sci U S A</i> <b>108</b>: 15954<br /><br />Trovaslet-Leroy M, Musilova L, Renault F, Brazzolotto X, Misik J, Novotny L, Froment MT, Gillon E, Loiodice M, Verdier L, Masson P, Rochu D, Jun D, Nachon F (2011) <br />Organophosphate hydrolases as catalytic bioscavengers of organophosphorus nerve agents<br /><i>Toxicol Lett</i> <b>206</b>: 14<br /><br />Wandhammer M, Carletti E, van der Schans M, Gillon E, Nicolet Y, Masson P, Goeldner M, Noort D, Nachon F (2011) <br />Structural study of the complex stereoselectivity of human butyrylcholinesterase for the neurotoxic V-agents<br /><i>Journal of Biological Chemistry</i> <b>286</b>: 16783<br /><br />Carletti E, Colletier JP, Dupeux F, Trovaslet M, Masson P, Nachon F (2010) <br />Structural evidence that human acetylcholinesterase inhibited by tabun ages through O-dealkylation<br /><i>Journal of Medicinal Chemistry</i> <b>53</b>: 4002<br /><br />Jun D, Musilova L, Link M, Loiodice M, Nachon F, Rochu D, Renault F, Masson P (2010) <br />Preparation and characterization of methoxy polyethylene glycol-conjugated phosphotriesterase as a potential catalytic bioscavenger against organophosphate poisoning<br /><i>Chemico-Biological Interactions</i> <b>187</b>: 380<br /><br />Li B, Ricordel I, Schopfer LM, Baud F, Megarbane B, Masson P, Lockridge O (2010) <br />Dichlorvos, chlorpyrifos oxon and Aldicarb adducts of butyrylcholinesterase, detected by mass spectrometry in human plasma following deliberate overdose<br /><i>J Appl Toxicol</i> <b>30</b>: 559<br /><br />Li B, Ricordel I, Schopfer LM, Baud F, Megarbane B, Nachon F, Masson P, Lockridge O (2010) <br />Detection of adduct on tyrosine 411 of albumin in humans poisoned by dichlorvos<br /><i>Toxicol Sci</i> <b>116</b>: 23<br /><br />Masson P, Lockridge O (2010) <br />Butyrylcholinesterase for protection from organophosphorus poisons: catalytic complexities and hysteretic behavior<br /><i>Archives of Biochemistry & Biophysics</i> <b>494</b>: 107<br /><br />Masson P, Nachon F, Lockridge O (2010) <br />Structural approach to the aging of phosphylated cholinesterases<br /><i>Chemico-Biological Interactions</i> <b>187</b>: 157<br /><br />Nachon F, Carletti E, Worek F, Masson P (2010) <br />Aging mechanism of butyrylcholinesterase inhibited by an N-methyl analogue of tabun: implications of the trigonal-bipyramidal transition state rearrangement for the phosphylation or reactivation of cholinesterases<br /><i>Chemico-Biological Interactions</i> <b>187</b>: 44<br /><br />Renault F, Carus T, Clery-Barraud C, Elias M, Chabriere E, Masson P, Rochu D (2010) <br />Integrative analytical approach by capillary electrophoresis and kinetics under high pressure optimized for deciphering intrinsic and extrinsic cofactors that modulate activity and stability of human paraoxonase (PON1)<br /><i>Journal of Chromatography B Analyt Technol Biomed Life Sciences</i> <b>878</b>: 1346<br /><br />Schopfer LM, Grigoryan H, Li B, Nachon F, Masson P, Lockridge O (2010) <br />Mass spectral characterization of organophosphate-labeled, tyrosine-containing peptides: characteristic mass fragments and a new binding motif for organophosphates<br /><i>Journal of Chromatography B Analyt Technol Biomed Life Sciences</i> <b>878</b>: 1297<br /><br />Tormos JR, Wiley KL, Wang Y, Fournier D, Masson P, Nachon F, Quinn DM (2010) <br />Accumulation of tetrahedral intermediates in cholinesterase catalysis: a secondary isotope effect study<br /><i>Journal of the American Chemical Society</i> <b>132</b>: 17751<br /><br />Trovaslet-Leroy M, Jolivalt C, Froment MT, Brasme B, Lefebvre B, Daveloose D, Nachon F, Masson P (2010) <br />Application of laccase-mediator system (LMS) for the degradation of organophosphorus compounds<br /><i>Chemico-Biological Interactions</i> <b>187</b>: 393<br /><br />Carletti E, Aurbek N, Gillon E, Loiodice M, Nicolet Y, Fontecilla-Camps JC, Masson P, Thiermann H, Nachon F, Worek F (2009) <br />Structure-activity analysis of aging and reactivation of human butyrylcholinesterase inhibited by analogues of tabun.<br /><i>Biochemical Journal</i> <b>421</b>: 97<br /><br />Gabel F, Masson P, Froment MT, Doctor BP, Saxena A, Silman I, Zaccai G, Weik M (2009) <br />Direct correlation between molecular dynamics and enzymatic stability: a comparative neutron scattering study of native human butyrylcholinesterase and its aged soman conjugate<br /><i>Biophysical Journal</i> <b>96</b>: 1489<br /><br />Li B, Schopfer LM, Grigoryan H, Thompson CM, Hinrichs SH, Masson P, Lockridge O (2009) <br />Tyrosines of human and mouse transferrin covalently labeled by organophosphorus agents: a new motif for binding to proteins that have no active site serine<br /><i>Toxicol Sci</i> <b>107</b>: 144<br /><br />Li H, Ricordel I, Tong L, Schopfer LM, Baud F, Megarbane B, Maury E, Masson P, Lockridge O (2009) <br />Carbofuran poisoning detected by mass spectrometry of butyrylcholinesterase adduct in human serum<br /><i>J Appl Toxicol</i> <b>29</b>: 149<br /><br />Masson P, Carletti E, Nachon F (2009) <br />Structure, activities and biomedical applications of human butyrylcholinesterase<br /><i>Protein Pept Lett</i> <b>16</b>: 1215<br /><br />Sanson B, Nachon F, Colletier JP, Froment MT, Toker L, Greenblatt HM, Sussman JL, Ashani Y, Masson P, Silman I, Weik M (2009) <br />Crystallographic snapshots of nonaged and aged conjugates of soman with acetylcholinesterase, and of a ternary complex of the aged conjugate with pralidoxime<br /><i>Journal of Medicinal Chemistry</i> <b>52</b>: 7593<br /><br />Badiou A, Froment MT, Fournier D, Masson P, Belzunces LP (2008) <br />Hysteresis of insect acetylcholinesterase<br /><i>Chemico-Biological Interactions</i> <b>175</b>: 410<br /><br />Carletti E, Li H, Li B, Ekstrom F, Nicolet Y, Loiodice M, Gillon E, Froment MT, Lockridge O, Schopfer LM, Masson P, Nachon F (2008) <br />Aging of cholinesterases phosphylated by tabun proceeds through O-dealkylation<br /><i>Journal of the American Chemical Society</i> <b>130</b>: 16011<br /><br />Ding SJ, Carr J, Carlson JE, Tong L, Xue W, Li Y, Schopfer LM, Li B, Nachon F, Asojo OA, Thompson CM, Hinrichs SH, Masson P, Lockridge O (2008) <br />Five tyrosines and two serines in human albumin are labeled by the organophosphorus agent FP-biotin<br /><i>Chemical Research in Toxicology</i> <b>21</b>: 1787<br /><br />Dorandeu F, Foquin A, Briot R, Delacour C, Denis J, Alonso A, Froment MT, Renault F, Lallement G, Masson P (2008) <br />An unexpected plasma cholinesterase activity rebound after challenge with a high dose of the nerve agent VX<br /><i>Toxicology</i> <b>248</b>: 151<br /><br />Elias M, Dupuy J, Merone L, Mandrich L, Porzio E, Moniot S, Rochu D, Lecomte C, Rossi M, Masson P, Manco G, Chabriere E (2008) <br />Structural basis for natural lactonase and promiscuous phosphotriesterase activities<br /><i>Journal of Molecular Biology</i> <b>379</b>: 1017<br /><br />Grigoryan H, Schopfer LM, Thompson CM, Terry AV, Masson P, Lockridge O (2008) <br />Mass spectrometry identifies covalent binding of soman, sarin, chlorpyrifos oxon, diisopropyl fluorophosphate, and FP-biotin to tyrosines on tubulin: a potential mechanism of long term toxicity by organophosphorus agents<br /><i>Chemico-Biological Interactions</i> <b>175</b>: 180<br /><br />Li B, Nachon F, Froment MT, Verdier L, Debouzy JC, Brasme B, Gillon E, Schopfer LM, Lockridge O, Masson P (2008) <br />Binding and hydrolysis of soman by human serum albumin<br /><i>Chemical Research in Toxicology</i> <b>21</b>: 421<br /><br />Li H, Schopfer LM, Masson P, Lockridge O (2008) <br />Lamellipodin proline rich peptides associated with native plasma butyrylcholinesterase tetramers<br /><i>Biochemical Journal</i> <b>411</b>: 425<br /><br />Li H, Tong L, Schopfer LM, Masson P, Lockridge O (2008) <br />Fast affinity purification coupled with mass spectrometry for identifying organophosphate labeled plasma butyrylcholinesterase<br /><i>Chemico-Biological Interactions</i> <b>175</b>: 68<br /><br />Lockridge O, Xue W, Gaydess A, Grigoryan H, Ding SJ, Schopfer LM, Hinrichs SH, Masson P (2008) <br />Pseudo-esterase activity of human albumin: slow turnover on tyrosine 411 and stable acetylation of 82 residues including 59 lysines<br /><i>Journal of Biological Chemistry</i> <b>283</b>: 22582<br /><br />Masson P, Nachon F, Broomfield CA, Lenz DE, Verdier L, Schopfer LM, Lockridge O (2008) <br />A collaborative endeavor to design cholinesterase-based catalytic scavengers against toxic organophosphorus esters<br /><i>Chemico-Biological Interactions</i> <b>175</b>: 273<br /><br />Masson P, Froment MT, Gillon E, Nachon F, Lockridge O, Schopfer LM (2008) <br />Kinetic analysis of effector modulation of butyrylcholinesterase-catalysed hydrolysis of acetanilides and homologous esters<br /><i>Febs J</i> <b>275</b>: 2617<br /><br />Colletier JP, Royant A, Specht A, Sanson B, Nachon F, Masson P, Zaccai G, Sussman JL, Goeldner M, Silman I, Bourgeois D, Weik M (2007) <br />Use of a 'caged' analogue to study the traffic of choline within acetylcholinesterase by kinetic crystallography<br /><i>Acta Crystallographica D Biol Crystallogr</i> <b>63</b>: 1115<br /><br />Li B, Schopfer LM, Hinrichs SH, Masson P, Lockridge O (2007) <br />Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry assay for organophosphorus toxicants bound to human albumin at Tyr411<br /><i>Analytical Biochemistry</i> <b>361</b>: 263<br /><br />Li H, Schopfer LM, Nachon F, Froment MT, Masson P, Lockridge O (2007) <br />Aging pathways for organophosphate-inhibited human butyrylcholinesterase, including novel pathways for isomalathion, resolved by mass spectrometry<br /><i>Toxicol Sci</i> <b>100</b>: 136<br /><br />Masson P, Froment MT, Darvesh S, Schopfer LM, Lockridge O (2007) <br />Aryl acylamidase activity of human serum albumin with o-nitrotrifluoroacetanilide as the substrate<br /><i>J Enzyme Inhib Med Chem</i> <b>22</b>: 463<br /><br />Masson P, Froment MT, Gillon E, Nachon F, Lockridge O, Schopfer LM (2007) <br />Hydrolysis of oxo- and thio-esters by human butyrylcholinesterase<br /><i>Biochimica & Biophysica Acta</i> <b>1774</b>: 16<br /><br />Masson P, Froment MT, Gillon E, Nachon F, Darvesh S, Schopfer LM (2007) <br />Kinetic analysis of butyrylcholinesterase-catalyzed hydrolysis of acetanilides<br /><i>Biochimica & Biophysica Acta</i> <b>1774</b>: 1139<br /><br />Rochu D, Chabriere E, Renault F, Elias M, Clery-Barraud C, Masson P (2007) <br />Stabilization of the active form(s) of human paraoxonase by human phosphate-binding protein<br /><i>Biochemical Society Transactions</i> <b>35</b>: 1616<br /><br />Hrabovska A, Debouzy JC, Froment MT, Devinsky F, Paulikova I, Masson P (2006) <br />Rat butyrylcholinesterase-catalysed hydrolysis of N-alkyl homologues of benzoylcholine<br /><i>Febs J</i> <b>273</b>: 1185<br /><br />Masurier N, Estour F, Lefevre B, Brasme B, Masson P, Lafont O (2006) <br />Improved access to 2-O-monobenzyl ethers of beta-cyclodextrin as precursors of catalysts for organophosphoryl esters hydrolysis<br /><i>Carbohydr Res</i> <b>341</b>: 935<br /><br />Poyot T, Nachon F, Froment MT, Loiodice M, Wieseler S, Schopfer LM, Lockridge O, Masson P (2006) <br />Mutant of Bungarus fasciatus acetylcholinesterase with low affinity and low hydrolase activity toward organophosphorus esters<br /><i>Biochimica & Biophysica Acta</i> <b>1764</b>: 1470<br /><br />Rochu D, Clery-Barraud C, Renault F, Chevalier A, Bon C, Masson P (2006) <br />Capillary electrophoresis versus differential scanning calorimetry for the analysis of free enzyme versus enzyme-ligand complexes: in the search of the ligand-free status of cholinesterases<br /><i>Electrophoresis</i> <b>27</b>: 442<br /><br />Gabel F, Weik M, Masson P, Renault F, Fournier D, Brochier L, Doctor BP, Saxena A, Silman I, Zaccai G (2005) <br />Effects of soman inhibition and of structural differences on cholinesterase molecular dynamics: a neutron scattering study<br /><i>Biophysical Journal</i> <b>89</b>: 3303<br /><br />Li B, Sedlacek M, Manoharan I, Boopathy R, Duysen EG, Masson P, Lockridge O (2005) <br />Butyrylcholinesterase, paraoxonase, and albumin esterase, but not carboxylesterase, are present in human plasma<br /><i>Biochemical Pharmacology</i> <b>70</b>: 1673<br /><br />Marchal S, Torrent J, Masson P, Kornblatt JM, Tortora P, Fusi P, Lange R, Balny C (2005) <br />The powerful high pressure tool for protein conformational studies<br /><i>Brazilian Journal of Medical & Biological Research</i> <b>38</b>: 1175<br /><br />Masson P, Schopfer LM, Froment MT, Debouzy JC, Nachon F, Gillon E, Lockridge O, Hrabovska A, Goldstein BN (2005) <br />Hysteresis of butyrylcholinesterase in the approach to steady-state kinetics<br /><i>Chemico-Biological Interactions</i> <b>157-158</b>: 143<br /><br />Masurier N, Estour F, Froment MT, Lefevre B, Debouzy JC, Brasme B, Masson P, Lafont O (2005) <br />Synthesis of 2-substituted beta-cyclodextrin derivatives with a hydrolytic activity against the organophosphorylester paraoxon<br /><i>Eur Journal of Medicinal Chemistry</i> <b>40</b>: 615<br /><br />Nachon F, Asojo OA, Borgstahl GE, Masson P, Lockridge O (2005) <br />Role of water in aging of human butyrylcholinesterase inhibited by echothiophate: the crystal structure suggests two alternative mechanisms of aging<br /><i>Biochemistry</i> <b>44</b>: 1154<br /><br />Nachon F, Nicolet Y, Masson P (2005) <br />[Butyrylcholinesterase: 3D structure, catalytic mechanisms]<br /><i>Ann Pharm Fr</i> <b>63</b>: 194<br /><br />Nachon F, Asojo OA, Borgstahl GE, Masson P, Lockridge O (2005) <br />Structural data on the aging of diethylphosphoryl-butyrylcholinesterase<br /><i>Chemico-Biological Interactions</i> <b>157-158</b>: 408<br /><br />Tormos JR, Wiley KL, Seravalli J, Nachon F, Masson P, Nicolet Y, Quinn DM (2005) <br />The reactant state for substrate-activated turnover of acetylthiocholine by butyrylcholinesterase is a tetrahedral intermediate<br /><i>Journal of the American Chemical Society</i> <b>127</b>: 14538<br /><br />Gabel F, Weik M, Doctor BP, Saxena A, Fournier D, Brochier L, Renault F, Masson P, Silman I, Zaccai G (2004) <br />The influence of solvent composition on global dynamics of human butyrylcholinesterase powders: a neutron-scattering study<br /><i>Biophysical Journal</i> <b>86</b>: 3152<br /><br />Masson P, Goldstein BN, Debouzy JC, Froment MT, Lockridge O, Schopfer LM (2004) <br />Damped oscillatory hysteretic behaviour of butyrylcholinesterase with benzoylcholine as substrate<br /><i>European Journal of Biochemistry</i> <b>271</b>: 220<br /><br />Masson P, Froment MT, Nachon F, Schopfer LM (2004) <br />Hysteresis in butyrylcholinesterase catalysis.<br /><i>Cholinergic Mechanisms, CRC Press</i> <br /><br />Masson P, Froment MT, Nachon F, Lockridge O, Schopfer LM (2004) <br />Hysteretic behavior of butyrylcholinesterase: Kinetic curiosity or catalytically and physiologicaly significant?<br /><i>In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects</i> <b> (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina</b>: 191 <br /><br />Masson P, Bec N, Froment MT, Nachon F, Balny C, Lockridge O, Schopfer LM (2004) <br />Rate-determining step of butyrylcholinesterase-catalyzed hydrolysis of benzoylcholine and benzoylthiocholine. Volumetric study of wild-type and D70G mutant behavior<br /><i>European Journal of Biochemistry</i> <b>271</b>: 1980<br /><br />Masson P, Froment MT, Nachon F, Lockridge O, Schopfer LM (2004) <br />Poster (20) Hysteretic behavior of butyrylcholinesterase : kinetic curiosity or catalytically and physiologically significant?<br /><i>In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects</i> <b> (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina</b>: 331<br /><br />Nachon F, Nicolet Y, Masson P, Lockridge O, Fontecilla-Camps JC (2004) <br />X-Ray structures of native and soman-aged human butyrylcholinesterase.<br /><i>Cholinergic Mechanisms, CRC Press</i> <br /><br />Nachon F, Nicolet Y, Masson P, Lockridge O, Fontecilla-Camps JC (2004) <br />Poster (93) How do the crystal structures of human butyrylcholinesterase compare to torpedo californica acetylcholinesterases structures?<br /><i>In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects</i> <b> (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina</b>: 369<br /><br />Nicolet Y, Lockridge O, Masson P, Fontecilla-Camps JC, Nachon F (2004) <br />Poster (49) Crystallographic basis for substrate/product exchange in cholinesterases.<br /><i>In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects</i> <b> (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina</b>: 347<br /><br />Rochu D, Viguie N, Renault F, Crouzier D, Froment MT, Masson P (2004) <br />Contribution of the active-site metal cation to the catalytic activity and to the conformational stability of phosphotriesterase: temperature- and pH-dependence<br /><i>Biochemical Journal</i> <b>380</b>: 627<br /><br />Rochu D, Renault F, Bon C, Masson P (2004) <br />Capillary zone electrophoresis detects unwanted cholinesterase-bound hidden ligands that alter enzyme conformational stability.<br /><i>Cholinergic Mechanisms, CRC Press</i> <br /><br />Wang Y, Schopfer LM, Duysen EG, Nachon F, Masson P, Lockridge O (2004) <br />Screening assays for cholinesterases resistant to inhibition by organophosphorus toxicants<br /><i>Analytical Biochemistry</i> <b>329</b>: 131<br /><br />Loudwig S, Nicolet Y, Masson P, Fontecilla-Camps JC, Bon S, Nachon F, Goeldner M (2003) <br />Photoreversible inhibition of cholinesterases: catalytic serine-labeled caged butyrylcholinesterase<br /><i>Chembiochem</i> <b>4</b>: 762<br /><br />Masson P, Nachon F, Bartels CF, Froment MT, Ribes F, Matthews C, Lockridge O (2003) <br />High activity of human butyrylcholinesterase at low pH in the presence of excess butyrylthiocholine<br /><i>European Journal of Biochemistry</i> <b>270</b>: 315<br /><br />Nicolet Y, Lockridge O, Masson P, Fontecilla-Camps JC, Nachon F (2003) <br />Crystal structure of human butyrylcholinesterase and of its complexes with substrate and products<br /><i>Journal of Biological Chemistry</i> <b>278</b>: 41141<br /><br />Clery-Barraud C, Ordentlich A, Grosfeld H, Shafferman A, Masson P (2002) <br />Pressure and heat inactivation of recombinant human acetylcholinesterase. Importance of residue E202 for enzyme stability<br /><i>European Journal of Biochemistry</i> <b>269</b>: 4297<br /><br />Masson P, Froment MT, Fort S, Ribes F, Bec N, Balny C, Schopfer LM (2002) <br />Butyrylcholinesterase-catalyzed hydrolysis of N-methylindoxyl acetate: analysis of volume changes upon reaction and hysteretic behavior<br /><i>Biochimica & Biophysica Acta</i> <b>1597</b>: 229<br /><br />Masson P, Schopfer LM, Bartels CF, Froment MT, Ribes F, Nachon F, Lockridge O (2002) <br />Substrate activation in acetylcholinesterase induced by low pH or mutation in the pi-cation subsite<br /><i>Biochimica & Biophysica Acta</i> <b>1594</b>: 313<br /><br />Nachon F, Nicolet Y, Viguie N, Masson P, Fontecilla-Camps JC, Lockridge O (2002) <br />Engineering of a monomeric and low-glycosylated form of human butyrylcholinesterase: expression, purification, characterization and crystallization<br /><i>European Journal of Biochemistry</i> <b>269</b>: 630<br /><br />Rochu D, Renault F, Masson P (2002) <br />Detection of unwanted protein-bound ligands by capillary zone electrophoresis: the case of hidden ligands that stabilize cholinesterase conformation<br /><i>Electrophoresis</i> <b>23</b>: 930<br /><br />Stojan J, Golicnik M, Froment MT, Estour F, Masson P (2002) <br />Concentration-dependent reversible activation-inhibition of human butyrylcholinesterase by tetraethylammonium ion<br /><i>European Journal of Biochemistry</i> <b>269</b>: 1154<br /><br />Josse D, Lockridge O, Xie W, Bartels CF, Schopfer LM, Masson P (2001) <br />The active site of human paraoxonase (PON1)<br /><i>J Appl Toxicol</i> <b>21 Suppl 1</b>: S7<br /><br />Masson P, Xie W, Froment MT, Lockridge O (2001) <br />Effects of mutations of active site residues and amino acids interacting with the Omega loop on substrate activation of butyrylcholinesterase<br /><i>Biochimica & Biophysica Acta</i> <b>1544</b>: 166<br /><br />Rochu D, Pernet T, Renault F, Bon C, Masson P (2001) <br />Dual effect of high electric field in capillary electrophoresis study of the conformational stability of Bungarus fasciatus acetylcholinesterase<br /><i>Journal of Chromatography A</i> <b>910</b>: 347<br /><br />Rochu D, Georges C, Repiton J, Viguie N, Saliou B, Bon C, Masson P (2001) <br />Thermal stability of acetylcholinesterase from Bungarus fasciatus venom as investigated by capillary electrophoresis<br /><i>Biochimica & Biophysica Acta</i> <b>1545</b>: 216<br /><br />Weingand-Ziade A, Ribes F, Renault F, Masson P (2001) <br />Pressure- and heat-induced inactivation of butyrylcholinesterase: evidence for multiple intermediates and the remnant inactivation process<br /><i>Biochemical Journal</i> <b>356</b>: 487<br /><br />Lockridge O, Masson P (2000) <br />Pesticides and susceptible populations: people with butyrylcholinesterase genetic variants may be at risk<br /><i>Neurotoxicology</i> <b>21</b>: 113<br /><br />Josse D, Xie W, Renault F, Rochu D, Schopfer LM, Masson P, Lockridge O (1999) <br />Identification of residues essential for human paraoxonase (PON1) arylesterase/organophosphatase activities<br /><i>Biochemistry</i> <b>38</b>: 2816<br /><br />Josse D, Xie W, Masson P, Lockridge O (1999) <br />Human serum paraoxonase (PON1): identification of essential amino acid residues by group-selective labelling and site-directed mutagenesis<br /><i>Chemico-Biological Interactions</i> <b>119-120</b>: 71<br /><br />Josse D, Xie W, Masson P, Schopfer LM, Lockridge O (1999) <br />Tryptophan residue(s) as major components of the human serum paraoxonase active site<br /><i>Chemico-Biological Interactions</i> <b>119-120</b>: 79<br /><br />Levitsky V, Xie W, Froment MT, Lockridge O, Masson P (1999) <br />Polyol-induced activation by excess substrate of the D70G butyrylcholinesterase mutant<br /><i>Biochimica & Biophysica Acta</i> <b>1429</b>: 422<br /><br />Masson P, Fortier PL, Albaret C, Clery C, Guerra P, Lockridge O (1999) <br />Structural and hydration changes in the active site gorge of phosporhylated butyrylcholinesterase accompanying the aging process<br /><i>Chemico-Biological Interactions</i> <b>119-120</b>: 17<br /><br />Masson P, Xie W, Froment MT, Levitsky V, Fortier PL, Albaret C, Lockridge O (1999) <br />Interaction between the peripheral site residues of human butyrylcholinesterase, D70 and Y332, in binding and hydrolysis of substrates<br /><i>Biochimica & Biophysica Acta</i> <b>1433</b>: 281<br /><br />Masson P, Clery C, Guerra P, Redslob A, Albaret C, Fortier PL (1999) <br />Hydration change during the aging of phosphorylated human butyrylcholinesterase: importance of residues aspartate-70 and glutamate-197 in the water network as probed by hydrostatic and osmotic pressures<br /><i>Biochemical Journal</i> <b>343</b>: 361<br /><br />Pilotaz F, Masson P (1999) <br />[Huperzine a: an acetylcholinesterase inhibitor with high pharmacological potential]<br /><i>Ann Pharm Fr</i> <b>57</b>: 363<br /><br />Weingand-Ziade A, Renault F, Masson P (1999) <br />Differential effect of pressure and temperature on the catalytic behaviour of wild-type human butyrylcholinesterase and its D70G mutant<br /><i>European Journal of Biochemistry</i> <b>264</b>: 327<br /><br />Albaret C, Masson P, Broomfield CA, Kaim LE, Fortier PL (1998) <br />Mechanical Aspects of the Phosphotriesterase Activity of Human Butyrylcholinesterase G117H Mutant<br /><i>In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases</i> <b>(Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp.</b>: 399<br /><br />Albaret C, Masson P, Broomfield CA, Kaim LE, Fortier PL (1998) <br />Poster: Mechanical Aspects of the Phosphotriesterase Activity of Human Butyrylcholinesterase G117H Mutant<br /><i>In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases</i> <b>(Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp.</b>: 434<br /><br />Froment MT, Lockridge O, Masson P (1998) <br />Resistance of butyrylcholinesterase to inactivation by ultrasound: effects of ultrasound on catalytic activity and subunit association<br /><i>Biochimica & Biophysica Acta</i> <b>1387</b>: 53<br /><br />Froment MT, Clery C, Weingand-Ziade A, Masson P (1998) <br />Stability of the Quaternary Structure of Butyrylcholinesterase Subjected to Ultrasound or Hydrostatic Pressure<br /><i>In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases</i> <b>(Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp.</b>: 436<br /><br />Marcel V, Palacios LG, Pertuy C, Masson P, Fournier D (1998) <br />Two invertebrate acetylcholinesterases show activation followed by inhibition with substrate concentration<br /><i>Biochemical Journal</i> <b>329</b>: 329<br /><br />Masson P, Froment MT, Fortier PL, Visicchio JE, Bartels CF, Lockridge O (1998) <br />Butyrylcholinesterase-catalysed hydrolysis of aspirin, a negatively charged ester, and aspirin-related neutral esters<br /><i>Biochimica & Biophysica Acta</i> <b>1387</b>: 41<br /><br />Masson P, Clery C, Guerra P, Fortier PL, Albaret C, Lockridge O (1998) <br />Structural Changes in the Active Site Gorge of Phosphylated Cholinesterase Accompanying the Aging Process<br /><i>In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases</i> <b>(Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp.</b>: 419<br /><br />Masson P, Josse D, Lockridge O, Viguie N, Taupin C, Buhler C (1998) <br />Enzymes hydrolyzing organophosphates as potential catalytic scavengers against organophosphate poisoning<br /><i>Journal de Physiologie (Paris)</i> <b>92</b>: 357<br /><br />Polyzou A, Froment MT, Masson P, Belzunces LP (1998) <br />Shielding of Acetylcholinesterase does not Result in the Protection of Honey Bee against Poisoning by Organophosphates<br /><i>In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases</i> <b>(Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp.</b>: 552<br /><br />Polyzou A, Froment MT, Masson P, Belzunces LP (1998) <br />Absence of a protective effect of the oxime 2-PAM toward paraoxon-poisoned honey bees: acetylcholinesterase reactivation not at fault<br /><i>Toxicol Appl Pharmacol</i> <b>152</b>: 184<br /><br />Rochu D, Rothlisberger C, Taupin C, Renault F, Gagnon J, Masson P (1998) <br />Purification, molecular characterization and catalytic properties of a Pseudomonas fluorescens enzyme having cholinesterase-like activity<br /><i>Biochimica & Biophysica Acta</i> <b>1385</b>: 126<br /><br />Stojan J, Marcel V, Estrada-Mondaca S, Klaebe A, Masson P, Fournier D (1998) <br />A putative kinetic model for substrate metabolisation by Drosophila acetylcholinesterase<br /><i>FEBS Letters</i> <b>440</b>: 85<br /><br />Lockridge O, Blong RM, Masson P, Froment MT, Millard CB, Broomfield CA (1997) <br />A single amino acid substitution, Gly117His, confers phosphotriesterase (organophosphorus acid anhydride hydrolase) activity on human butyrylcholinesterase<br /><i>Biochemistry</i> <b>36</b>: 786<br /><br />Masson P, Legrand P, Bartels CF, Froment MT, Schopfer LM, Lockridge O (1997) <br />Role of aspartate 70 and tryptophan 82 in binding of succinyldithiocholine to human butyrylcholinesterase<br /><i>Biochemistry</i> <b>36</b>: 2266<br /><br />Masson P, Fortier PL, Albaret C, Froment MT, Bartels CF, Lockridge O (1997) <br />Aging of di-isopropyl-phosphorylated human butyrylcholinesterase<br /><i>Biochemical Journal</i> <b>327 ( Pt 2)</b>: 601<br /><br />Masson P, Froment MT, Bartels CF, Lockridge O (1997) <br />Importance of aspartate-70 in organophosphate inhibition, oxime re-activation and aging of human butyrylcholinesterase<br /><i>Biochemical Journal</i> <b>325</b>: 53<br /><br />Weingand-Ziade A, Renault F, Masson P (1997) <br />Combined pressure/heat-induced inactivation of butyrylcholinesterase<br /><i>Biochimica & Biophysica Acta</i> <b>1340</b>: 245<br /><br />Masson P, Froment MT, Bartels CF, Lockridge O (1996) <br />Asp7O in the peripheral anionic site of human butyrylcholinesterase<br /><i>European Journal of Biochemistry</i> <b>235</b>: 36<br /><br />Aslanian D, Grof P, Renault F, Masson P (1995) <br />Raman spectroscopic study of conjugates of butyrylcholinesterase with organophosphates<br /><i>Biochimica & Biophysica Acta</i> <b>1249</b>: 37<br /><br />Blong RM, Masson P, Lockridge O (1995) <br />Subunit Association and Stabilization of Butyrylcholinesterase (BChE)<br /><i>In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases</i> <b>(Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp.</b>: 129<br /><br />Clery C, Heiber-Langer I, Channac L, David L, Balny C, Masson P (1995) <br />Substrate dependence of amiloride- and soman-induced conformation changes of butyrylcholinesterase as evidenced by high-pressure perturbation<br /><i>Biochimica & Biophysica Acta</i> <b>1250</b>: 19<br /><br />Clery C, Renault F, Masson P (1995) <br />Pressure-induced molten globule state of cholinesterase<br /><i>FEBS Letters</i> <b>370</b>: 212<br /><br />Clery C, Bec N, Balny C, Mozhaev VV, Masson P (1995) <br />Kinetics of butyrylcholinesterase in reversed micelles under high pressure<br /><i>Biochimica & Biophysica Acta</i> <b>1253</b>: 85<br /><br />Fournier D, Maturano M, Gagnoux L, Ziliani P, Pertuy C, Pralavorio M, Bride JM, Elmarbouh L, Klaebe A, Masson P (1995) <br />Insect Acetylcholinesterase and Resistance to Insecticides<br /><i>In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases</i> <b>(Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp.</b>: 149<br /><br />Lebleu M, Clery C, Masson P, Reuveny S, Marcus D, Velan B, Shafferman A (1995) <br />Denaturation of Recombinant Human Acetylcholinesterase<br /><i>In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases</i> <b>(Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp.</b>: 131<br /><br />Masson P, Clery C (1995) <br />Pressure Effects on Structure and Activity of Cholinesterase<br /><i>In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases</i> <b>(Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp.</b>: 113<br /><br />Masson P, Froment MT, Bartels CF, Lockridge O (1995) <br />Peripheral Anionic Site of Wild-Type and Mutant Human Butyrylcholinesterase<br /><i>In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases</i> <b>(Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp.</b>: 230<br /><br />Kris M, Jbilo O, Bartels CF, Masson P, Rhode S, Lockridge O (1994) <br />Endogenous butyrylcholinesterase in SV40 transformed cell lines: COS-1, COS-7, MRC-5 SV40, and WI-38 VA13<br /><i>In Vitro Cellular & Developmental Biology Animal</i> <b>10</b>: 680<br /><br />Masson P, Gouet P, Clery C (1994) <br />Pressure and propylene carbonate denaturation of native and aged phosphorylated cholinesterase<br /><i>Journal of Molecular Biology</i> <b>238</b>: 466<br /><br />Masson P, Froment MT, Sorenson RC, Bartels CF, Lockridge O (1994) <br />Mutation His322Asn in human acetylcholinesterase does not alter electrophoretic and catalytic properties of the erythrocyte enzyme<br /><i>Blood</i> <b>83</b>: 3003<br /><br />Curtil C, Masson P (1993) <br />[Aging of cholinesterase after inhibition by organophosphates].<br /><i>Ann Pharm Fr</i> <b>51</b>: 63<br /><br />Masson P, Adkins S, Gouet P, Lockridge O (1993) <br />Recombinant human butyrylcholinesterase G390V, the fluoride-2 variant, expressed in Chinese hamster ovary cells, is a low affinity variant<br /><i>Journal of Biological Chemistry</i> <b>268</b>: 14329<br /><br />Clery C, Masson P, Heiber-Langer I, Balny C (1992) <br />Soman inhibition of butyrylcholinesterase in the presence of substrate: pressure and temperature perturbations<br /><i>Biochimica & Biophysica Acta</i> <b>1159</b>: 295<br /><br />Masson P, Adkins S (1992) <br />Expression and Refolding of Functional Human Butyrylcholinesterase from E. Coli<br /><i>In Multidisciplinary approaches to cholinesterase functions - Proceedings of Fourth International Meeting on Cholinesterases</i> <b>(Shafferman, A. and Velan, B., Eds) Plenum Press, New York</b>: 49<br /><br />Arpagaus M, Chatonnet A, Masson P, Newton M, Vaughan TA, Bartels CF, Nogueira CP, La Du BN, Lockridge O (1991) <br />Use of the polymerase chain reaction for homology probing of butyrylcholinesterase from several vertebrates<br /><i>Journal of Biological Chemistry</i> <b>266</b>: 6966<br /><br />Arpagaus M, Vaughan TA, La Du BN, Lockridge O, Masson P, Chatonnet A, Newton M, Taylor P (1991) <br />Poster: Use of the polymerase chain reaction for homology probing of butyrylchoIinesterase (BCHE) in several animal species<br /><i>In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology</i> <b>(Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC</b>: 194<br /><br />Aslanian D, Grof P, Masson P, Taylor P, Bon S, Chatel JM, Massoulie J (1991) <br />Poster: A comparative raman spectroscopic study of cholinesterases<br /><i>In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology</i> <b>(Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC</b>: 56<br /><br />Aslanian D, Grof P, Bon S, Masson P, Negrerie M, Chatel JM, Balkanski M, Taylor P, Massoulie J (1991) <br />A comparative Raman spectroscopic study of cholinesterases<br /><i>Biochimie</i> <b>73</b>: 1375<br /><br />Masson P (1991) <br />Molecular Heterogeneity of Human Plasma Cholinesterase<br /><i>In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology</i> <b>(Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC</b>: 42<br /><br />Masson P, Clery C, Huchet D (1991) <br />Poster: Stability of native and organophosphate-inhibited butyry1cholinesterase under high pressure<br /><i>In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology</i> <b>(Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC</b>: 275<br /><br />Masson P, Froment MT, Audras JC, Renault F (1991) <br />Poster: Molecular characterization of the C5 human plasma cholinesterase variant<br /><i>In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology</i> <b>(Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC</b>: 60<br /><br />Masson P (1991) <br />Structural and functional investigations of cholinesterases by means of affinity electrophoresis<br /><i>Cellular Molecular Neurobiology</i> <b>11</b>: 173<br /><br />Checler F, Grassi J, Masson P, Vincent JP (1990) <br />Monoclonal antibodies allow precipitation of esterasic but not peptidasic activities associated with butyrylcholinesterase<br /><i>Journal of Neurochemistry</i> <b>55</b>: 750<br /><br />Masson P, Chatonnet A, Lockridge O (1990) <br />Evidence for a single butyrylcholinesterase gene in individuals carrying the C5 plasma cholinesterase variant (CHE2)<br /><i>FEBS Letters</i> <b>262</b>: 115<br /><br />Masson P, Balny C (1990) <br />Conformational plasticity of butyrylcholinesterase as revealed by high pressure experiments<br /><i>Biochimica & Biophysica Acta</i> <b>1041</b>: 223<br /><br />Masson P (1989) <br />A naturally occurring molecular form of human plasma cholinesterase is an albumin conjugate<br /><i>Biochimica & Biophysica Acta</i> <b>998</b>: 258<br /><br />Masson P, Balny C (1988) <br />Effects of high pressure on the single-turnover kinetics of the carbamylation of cholinesterase<br /><i>Biochimica & Biophysica Acta</i> <b>954</b>: 208<br /><br />Masson P, Laurentie M (1988) <br />Stability of butyrylcholinesterase: thermal inactivation in water and deuterium oxide<br /><i>Biochimica & Biophysica Acta</i> <b>957</b>: 111<br /><br />Ferro A, Masson P (1987) <br />Kinetic evidence for thermally induced conformational change of butyrylcholinesterase<br /><i>Biochimica & Biophysica Acta</i> <b>916</b>: 193<br /><br />Chatonnet A, Masson P (1986) <br />Is the peptidase activity of highly purified human plasma cholinesterase due to a specific cholinesterase isoenzyme or a contaminating dipeptidylaminopeptidase?<br /><i>Biochimie</i> <b>68</b>: 657<br /><br />Masson P, Goasdoue JL (1986) <br />Evidence that the conformational stability of 'aged' organophosphate-inhibited cholinesterase is altered<br /><i>Biochimica & Biophysica Acta</i> <b>869</b>: 304<br /><br />Masson P, Balny C (1986) <br />Thermodynamic arguments for temperature-induced cryptic conformational change of human plasma cholinesterase<br /><i>Biochimica & Biophysica Acta</i> <b>874</b>: 90<br /><br />Chatonnet A, Masson P (1985) <br />Study of the peptidasic site of cholinesterase: preliminary results<br /><i>FEBS Letters</i> <b>182</b>: 493<br /><br />Masson P, Marnot B (1985) <br />[Affinity electrophoresis in polyacrylamide gel. Influence of the concentration in the gel on the apparent affinity of cholinesterase for an anionic ligand site]. [French]<br /><i>Journal of Chromatography</i> <b>328</b>: 135<br /><br />Chatonnet A, Masson P (1984) <br />[The peptidase site of butyrylcholinesterase is distinct from the esterase site]. [French]<br /><i>Comptes Rendus de l Academie des Sciences</i> <b>299</b>: 529<br /><br />Masson P, Marnot B, Lombard JY, Morelis P (1984) <br />Poster 84. Electrophoretic studies of the aged soman-inhibited butyrylcholinesterase<br /><i>In: Cholinesterases, fundamental and applied aspects : proceedings of the Second International Meeting on Cholinesterases</i> <b>(Brzin M, Barnard EA, Sket D, Eds) De Gruyter</b>: <br /><br />Masson P, Marnot B, Lombard JY, Morelis P (1984) <br />[Electrophoretic study of aged butyrylcholinesterase after inhibition by soman]. [French]<br /><i>Biochimie</i> <b>66</b>: 235<br /><br />Masson P, Vallin P (1983) <br />[Possibilities of study of the human plasma cholinesterase variants by affinity electrophoresis]. [French]<br /><i>Journal of Chromatography</i> <b>273</b>: 289<br /><br />Masson P, Privat de Garilhe A, Burnat P (1982) <br />[Multiple molecular forms of human plasma butyrylcholinesterase. II.-Study of the C1, C3 and C4 components by means of affinity electrophoresis (author's transl)]. [French]<br /><i>Biochimica & Biophysica Acta</i> <b>701</b>: 269<br /><br />Masson P, Sussmilch A, Charlet JP (1980) <br />[Purification of butyrylcholinesterase from human plasma]. [French]<br /><i>Comptes Rendus de l Academie des Sciences</i> <b>290</b>: 857<br /><br />Masson P (1979) <br />[Multiple molecular forms of human plasma butyrylcholinesterase. I. Apparent molecular parameters and broad pattern of the quaternary structure (author's transl)]. [French]<br /><i>Biochimica & Biophysica Acta</i> <b>578</b>: 493<br /><br />Masson P, Germani F, Plasse M (1979) <br />[Frequency of locus E1 variants of plasma butyrylcholinesterase in a French population]. [French]<br /><i>Comptes Rendus de l Academie des Sciences</i> <b>289</b>: 537<br /><br />Masson P (1979) <br />[Determination of free electrophoretic mobility of proteins by gradient polyacrylamide electrophoresis]. [French]<br /><i>Journal of Chromatography</i> <b>169</b>: 386<br /><br />