Parvez MM, Basit A, Jariwala PB, Gaborik Z, Kis E, Heyward S, Redinbo MR, Prasad B (2021)
Quantitative investigation of irinotecan metabolism, transport and gut microbiome activation
Drug Metabolism & Disposition: The Biological Fate of Chemicals

Roberts AB, Wallace BD, Venkatesh MK, Mani S, Redinbo MR (2013)
Molecular Insights into Microbial beta-Glucuronidase Inhibition to Abrogate CPT-11 Toxicity
Molecular Pharmacology 84: 208

Edwards JS, Kumbhar A, Roberts A, Hemmert AC, Edwards CC, Potter PM, Redinbo MR (2011)
Immobilization of active human carboxylesterase 1 in biomimetic silica nanoparticles
Biotechnol Prog 27: 863

Hemmert AC, Otto TC, Chica RA, Wierdl M, Edwards JS, Lewis SM, Edwards CC, Tsurkan L, Cadieux CL, Kasten SA, Cashman JR, Mayo SL, Potter PM, Cerasoli DM, Redinbo MR (2011)
Nerve agent hydrolysis activity designed into a human drug metabolism enzyme
PLoS ONE 6: e17441

Hemmert AC, Redinbo MR (2010)
A structural examination of agrochemical processing by human carboxylesterase 1
Journal of Pesticide Science 35: 250

Hemmert AC, Otto TC, Wierdl M, Edwards CC, Fleming CD, MacDonald M, Cashman JR, Potter PM, Cerasoli DM, Redinbo MR (2010)
Human carboxylesterase 1 stereoselectively binds the nerve agent cyclosarin and spontaneously hydrolyzes the nerve agent sarin
Molecular Pharmacology 77: 508

Holmes RS, Wright MW, Laulederkind SJ, Cox LA, Hosokawa M, Imai T, Ishibashi S, Lehner R, Miyazaki M, Perkins EJ, Potter PM, Redinbo MR, Robert J, Satoh T, Yamashita T, Yan B, Yokoi T, Zechner R, Maltais LJ (2010)
Recommended nomenclature for five mammalian carboxylesterase gene families: human, mouse, and rat genes and proteins
Mamm Genome 21: 427

Wierdl M, Tsurkan L, Hyatt JL, Edwards CC, Hatfield MJ, Morton CL, Houghton PJ, Danks MK, Redinbo MR, Potter PM (2008)
An improved human carboxylesterase for enzyme/prodrug therapy with CPT-11
Cancer Gene Therapy 15: 183

Fleming CD, Edwards CC, Kirby SD, Maxwell DM, Potter PM, Cerasoli DM, Redinbo MR (2007)
Crystal structures of human carboxylesterase 1 in covalent complexes with the chemical warfare agents soman and tabun
Biochemistry 46: 5063

Wadkins RM, Hyatt JL, Edwards CC, Tsurkan L, Redinbo MR, Wheelock CE, Jones PD, Hammock BD, Potter PM (2007)
Analysis of mammalian carboxylesterase inhibition by trifluoromethylketone-containing compounds
Molecular Pharmacology 71: 713

Bencharit S, Edwards CC, Morton CL, Howard-Williams EL, Kuhn P, Potter PM, Redinbo MR (2006)
Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1
Journal of Molecular Biology 363: 201

Fleming CD, Bencharit S, Edwards CC, Hyatt JL, Tsurkan L, Bai F, Fraga C, Morton CL, Howard-Williams EL, Potter PM, Redinbo MR (2005)
Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil
Journal of Molecular Biology 352: 165

Huang H, Fleming CD, Nishi K, Redinbo MR, Hammock BD (2005)
Stereoselective hydrolysis of pyrethroid-like fluorescent substrates by human and other mammalian liver carboxylesterases
Chemical Research in Toxicology 18: 1371

Redinbo MR, Potter PM (2005)
Mammalian carboxylesterases: from drug targets to protein therapeutics
Drug Discov Today 10: 313

Wierdl M, Morton CL, Nguyen NK, Redinbo MR, Potter PM (2004)
Molecular modeling of CPT-11 metabolism by carboxylesterases (CEs): use of pnb CE as a model
Biochemistry 43: 1874

Bencharit S, Morton CL, Xue Y, Potter PM, Redinbo MR (2003)
Structural basis of heroin and cocaine metabolism by a promiscuous human drug-processing enzyme
Nat Struct Biol 10: 349

Bencharit S, Morton CL, Hyatt JL, Kuhn P, Danks MK, Potter PM, Redinbo MR (2003)
Crystal structure of human carboxylesterase 1 complexed with the Alzheimer's drug tacrine: from binding promiscuity to selective inhibition
Chemical Biology 10: 341

Redinbo MR, Bencharit S, Potter PM (2003)
Human carboxylesterase 1: from drug metabolism to drug discovery
Biochemical Society Transactions 31: 620

Bencharit S, Morton CL, Howard-Williams EL, Danks MK, Potter PM, Redinbo MR (2002)
Structural insights into CPT-11 activation by mammalian carboxylesterases
Nat Struct Biol 9: 337