Fronza MG, Alves D, Pratico D, Savegnago L (2023) <br />The Neurobiology and Therapeutic Potential of Multi-Targeting beta-secretase, Glycogen Synthase Kinase 3beta and Acetylcholinesterase in Alzheimer's Disease<br /><i>Ageing Res Rev</i> <br /><br />Fronza MG, Sacramento M, Alves D, Pratico D, Savegnago L (2022) <br />1-(7-Chloroquinolin-4-yl)-N-(4-Methoxybenzyl)-5-Methyl-1H-1,2, 3-Triazole-4- carboxamide Reduces Abeta Formation and Tau Phosphorylation in Cellular Models of Alzheimer's Disease<br /><i>Neurochem Res</i> <br /><br />Fronza MG, Sacramento M, Alves D, Pratico D, Savegnago L (2022) <br />QTC-4-MeOBnE Ameliorated Depressive-Like Behavior and Memory Impairment in 3xTg Mice<br /><i>Molecular Neurobiology</i> <br /><br />Baldinotti R, Fronza MG, Silva L, Bender CB, Ludtke DS, Seixas FK, Collares T, Alves D, Savegnago L (2021) <br />Protective effects of octylseleno-xylofuranoside in a streptozotocin-induced mouse model of Alzheimer's disease<br /><i>European Journal of Pharmacology</i> <br /><br />Fronza MG, Baldinotti R, Sacramento M, Gutierres J, Carvalho FB, Fernandes MDC, Sousa FSS, Seixas FK, Collares T, Alves D, Pratico D, Savegnago L (2021) <br />Effect of QTC-4-MeOBnE Treatment on Memory, Neurodegeneration, and Neurogenesis in a Streptozotocin-Induced Mouse Model of Alzheimer's Disease<br /><i>ACS Chem Neurosci</i> <b>12</b>: 109<br /><br />Fronza MG, Baldinotti R, Fetter J, Goncalves Rosa S, Sacramento M, Wayne Nogueira C, Alves D, Pratic D, Savegnago L (2021) <br />Beneficial effects of QTC-4-MeOBnE in an LPS-induced mouse model of depression and cognitive impairments: the role of blood-brain barrier permeability, NF-kB signaling, and microglial activation<br /><i>Brain Behavior & Immunity</i> <br /><br />Pinz MP, Vogt AG, da Costa Rodrigues K, Dos Reis AS, Duarte LFB, Fronza MG, Domingues WB, Blodorn EB, Alves D, Campos VF, Savegnago L, Wilhelm EA, Luchese C (2021) <br />Effect of a purine derivative containing selenium to improve memory decline and anxiety through modulation of the cholinergic system and Na(+)/K(+)-ATPase in an Alzheimer's disease model<br /><i>Metabolic Brain Disease</i> <br /><br />da Costa Rodrigues K, Leivas de Oliveira R, da Silva Chaves J, Esteves da Rocha VM, Fuzinato Dos Santos B, Fronza MG, Luis de Campos Domingues N, Savegnago L, Wilhelm EA, Luchese C (2021) <br />A new arylsulfanyl-benzo-2,1,3-thiadiazoles derivative produces an anti-amnesic effect in mice by modulating acetylcholinesterase activity<br /><i>Chemico-Biological Interactions</i> <b>351</b>: 109736<br /><br />Costa GP, Baldinotti R, Fronza MG, Nascimento JE, Dias I, Sonego MS, Seixas FK, Collares T, Perin G, Jacob RG, Savegnago L, Alves D (2020) <br />Synthesis, molecular docking and preliminary evaluation of 2-(1,2,3-triazoyl)-benzaldehydes as multifunctional agents for the treatment of Alzheimer's disease<br /><i>ChemMedChem</i> <br /><br />Fronza MG, Baldinotti R, Fetter J, Sacramento M, Sousa FSS, Seixas FK, Collares T, Alves D, Pratico D, Savegnago L (2020) <br />QTC-4-MeOBnE rescues scopolamine-induced memory deficits in mice by targeting oxidative stress, neuronal plasticity and apoptosis<br /><i>ACS Chem Neurosci</i> <b>11</b>: 1259<br /><br />Bampi SR, Casaril AM, Sabedra Sousa FS, Pesarico AP, Vieira B, Lenardao EJ, Savegnago L (2019) <br />Repeated administration of a selenium-containing indolyl compound attenuates behavioural alterations by streptozotocin through modulation of oxidative stress in mice<br /><i>Pharmacol Biochem Behav</i> <b>183</b>: 46<br /><br />Fronza MG, Baldinotti R, Martins MC, Goldani B, Dalberto BT, Kremer FS, Begnini K, Pinto LDS, Lenardao EJ, Seixas FK, Collares T, Alves D, Savegnago L (2019) <br />Rational design, cognition and neuropathology evaluation of QTC-4-MeOBnE in a streptozotocin-induced mouse model of sporadic Alzheimer's disease<br /><i>Sci Rep</i> <b>9</b>: 7276<br /><br />Wilhelm EA, Jesse CR, Bortolatto CF, Nogueira CW, Savegnago L (2009) <br />Anticonvulsant and antioxidant effects of 3-alkynyl selenophene in 21-day-old rats on pilocarpine model of seizures<br /><i>Brain Research Bulletin</i> <b>79</b>: 281<br /><br />