Nuthakki VK, Choudhary S, Reddy CN, Bhatt S, Jamwal A, Jotshi A, Raghuvanshi R, Sharma A, Thakur S, Jadhav HR, Bharate SS, Nandi U, Kumar A, Bharate SB (2023) <br />Design, Synthesis, and Pharmacological Evaluation of Embelin-Aryl/alkyl Amine Hybrids as Orally Bioavailable Blood-Brain Barrier Permeable Multitargeted Agents with Therapeutic Potential in Alzheimer's Disease: Discovery of SB-1448<br /><i>ACS Chem Neurosci</i> <br /><br />Sharma A, Piplani P (2023) <br />Acridine: A Scaffold for the development of drugs for Alzheimer's disease<br /><i>Curr Top Med Chem</i> <br /><br />Sharma A, Bharate SB (2023) <br />Synthesis and Biological Evaluation of Coumarin Triazoles as Dual Inhibitors of Cholinesterases and beta-Secretase<br /><i>ACS Omega</i> <b>8</b>: 11161<br /><br />Sharma M, Sharma A, Thakur S, Nuthakki VK, Jamwal A, Nandi U, Jadhav HR, Bharate SB (2023) <br />Discovery of blood-brain barrier permeable and orally bioavailable caffeine-based amide derivatives as acetylcholinesterase inhibitors<br /><i>Bioorg Chem</i> <b>139</b>: 106719<br /><br />Sharma A, Kaur M, Sharma K, Bunkar SK, John P, Bhatnagar P (2023) <br />Nano polystyrene induced changes in anxiety and learning behaviour are mediated through oxidative stress and gene disturbance in mouse brain regions<br /><i>Neurotoxicology</i> <b>99</b>: 139<br /><br />Singh A, Singh K, Kaur J, Kaur R, Sharma A, Kaur U, Chadha R, Bedi PMS (2023) <br />Pathogenesis of Alzheimer's Disease and Diversity of 1,2,3-Triazole Scaffold in Drug Development: Design Strategies, Structural Insights, and Therapeutic Potential<br /><i>ACS Chem Neurosci</i> <br /><br />Gudi S, Saini DK, Singh G, Halladakeri P, Kumar P, Shamshad M, Tanin MJ, Singh S, Sharma A (2022) <br />Unravelling consensus genomic regions associated with quality traits in wheat using meta-analysis of quantitative trait loci<br /><i>Planta</i> <b>255</b>: 115<br /><br />Sharma T, Xia C, Sharma A, Raizada P, Singh P, Sharma S, Sharma P, Kumar S, Lam S, Nadda AK (2022) <br />Mechano-chemical and biological energetics of immobilized enzymes onto functionalized polymers and their applications<br /><i>Bioengineered</i> <b>13</b>: 10518<br /><br />Sharma A, Nuthakki VK, Gairola S, Singh B, Bharate SB (2022) <br />A Coumarin-donepezil Hybrid as a Blood-brain Barrier Permeable Dual Cholinesterase Inhibitor: Isolation, Synthetic Modifications and Biological Evaluation of Natural Coumarins<br /><i>ChemMedChem</i> <br /><br />Sharma M, Sharma A, Nuthakki VK, Bhatt S, Nandi U, Bharate SB (2022) <br />Design, synthesis, and structure-activity relationship of caffeine-based triazoles as dual AChE and BACE-1 inhibitors<br /><i>Drug Dev Res</i> <br /><br />Singh JV, Thakur S, Kumar N, Singh H, Mithu VS, Bhagat K, Gulati HK, Sharma A, Sharma S, Bedi PMS (2022) <br />Donepezil-Inspired Multitargeting Indanone Derivatives as Effective Anti-Alzheimer's Agents<br /><i>ACS Chem Neurosci</i> <br /><br />Thakur A, Patwa J, Pant S, Jeet Singh Flora S, Sharma A (2022) <br />Synthesis and evaluation of small organic molecule as reactivator of organophosphorus inhibited acetylcholinesterase<br /><i>Drug & Chemical Toxicology</i> <br /><br />Bajaj S, Aiwale A, Trailokya A, Sharma A (2021) <br />Clinical Evidence of Evogliptin plus Metformin in Management of Type 2 Diabetes mellitus<br /><i>J Assoc Physicians India</i> <b>69</b>: 25<br /><br />Bhardwaj KK, Kishen S, Mehta A, Sharma A, Gupta R (2021) <br />Purification of high molecular weight thermotolerant esterase from Serratia sp. and its characterization<br /><i>3 Biotech</i> <b>11</b>: 308<br /><br />Gori M, Thakur A, Sharma A, Flora SJS (2021) <br />Organic-Molecule-Based Fluorescent Chemosensor for Nerve Agents and Organophosphorus Pesticides<br /><i>Top Curr Chem (Cham)</i> <b>379</b>: 33<br /><br />Sharma A, Shrivastava S, Shukla S (2021) <br />Oxidative damage in the liver and brain of the rats exposed to frequency-dependent radiofrequency electromagnetic exposure: Biochemical and histopathological evidence<br /><i>Free Radical Research</i> <br /><br />Sharma A, Chun J, Ji MS, Lee S, Kang C, Kim JS (2021) <br />Binary Prodrug of Dichloroacetic Acid and Doxorubicin with Enhanced Anticancer Activity<br /><i>ACS Appl Bio Mater</i> <b>4</b>: 2026<br /><br />Singh G, Thaker R, Sharma A, Parmar D (2021) <br />Therapeutic effects of biochanin A, phloretin, and epigallocatechin-3-gallate in reducing oxidative stress in arsenic-intoxicated mice<br /><i>Environ Sci Pollut Res Int</i> <br /><br />Thakur A, Patwa J, Sharma A, Flora SJ (2021) <br />Synthesis, Molecular Docking, BSA, and in-vitro reactivation study of imidazopyridine oxime against paraoxon inhibited acetylcholinesterase<br /><i>Med Chem</i> <br /><br />Behl T, Sharma A, Sharma L, Sehgal A, Zengin G, Brata R, Fratila O, Bungau S (2020) <br />Exploring the Multifaceted Therapeutic Potential of Withaferin A and Its Derivatives<br /><i>Biomedicines</i> <b>8</b>: <br /><br />Dar OI, Sharma S, Singh K, Sharma A, Bhardwaj R, Kaur A (2020) <br />Biomarkers for the toxicity of sublethal concentrations of triclosan to the early life stages of carps<br /><i>Sci Rep</i> <b>10</b>: 17322<br /><br />Patwa J, Thakur A, Sharma A, Flora SJS (2020) <br />Monoisoamyl DMSA reduced copper-induced neurotoxicity by lowering 8-OHdG level, amyloid beta and Tau protein expressions in Sprague-Dawley rats<br /><i>Metallomics</i> <b>12</b>: 1428<br /><br />Prabhakar S, Vishnu VY, Modi M, Mohanty M, Sharma A, Medhi B, Mittal BR, Khandelwal N, Goyal MK, Lal V, Singla R, Kansal A, Avasthi A (2020) <br />Efficacy of Bacopa Monnieri (Brahmi) and Donepezil in Alzheimer's Disease and Mild Cognitive Impairment: A Randomized Double-Blind Parallel Phase 2b Study<br /><i>Ann Indian Acad Neurol</i> <b>23</b>: 767<br /><br />Chaudhary GR, Yadav PK, Yadav AK, Tiwari M, Gupta A, Sharma A, Sahu K, Pandey AN, Pandey AK, Chaube SK (2019) <br />Necrosis and necroptosis in germ cell depletion from mammalian ovary<br /><i>Journal of Cellular Physiology</i> <b>234</b>: 8019<br /><br />Nuthakki VK, Mudududdla R, Sharma A, Kumar A, Bharate SB (2019) <br />Synthesis and biological evaluation of indoloquinoline alkaloid cryptolepine and its bromo-derivative as dual cholinesterase inhibitors<br /><i>Bioorg Chem</i> <b>90</b>: 103062<br /><br />Nuthakki VK, Sharma A, Kumar A, Bharate SB (2019) <br />Identification of embelin, a 3-undecyl-1,4-benzoquinone from Embelia ribes as a multitargeted anti-Alzheimer agent<br /><i>Drug Dev Res</i> <b>80</b>: 655<br /><br />Park H, Min B, Jang Y, Kim J, Lipzen A, Sharma A, Andreopoulos B, Johnson J, Riley R, Spatafora JW, Henrissat B, Kim KH, Grigoriev IV, Kim JJ, Choi IG (2019) <br />Comprehensive genomic and transcriptomic analysis of polycyclic aromatic hydrocarbon degradation by a mycoremediation fungus, Dentipellis sp. KUC8613<br /><i>Applied Microbiology & Biotechnology</i> <b>103</b>: 8145<br /><br />Sharma A, Sharma S, Shrivastava S, Singhal PK, Shukla S (2019) <br />Mobile phone induced cognitive and neurochemical consequences<br /><i>Journal of Chemical Neuroanatomy</i> <br /><br />Kaur G, Sharma A, Narang T, Dogra S, Kaur J (2018) <br />Characterization of ML0314c of Mycobacterium leprae and deciphering its role in the immune response in leprosy patients<br /><i>Gene</i> <b>643</b>: 26<br /><br />Piplani P, Jain A, Devi D, Anjali, Sharma A, Silakari P (2018) <br />Design, synthesis and pharmacological evaluation of some novel indanone derivatives as acetylcholinesterase inhibitors for the management of cognitive dysfunction<br /><i>Bioorganic & Medicinal Chemistry</i> <b>26</b>: 215<br /><br />Sharma A, Meena KR, Kanwar SS (2018) <br />Molecular characterization and bioinformatics studies of a lipase from Bacillus thermoamylovorans BHK67<br /><i>Int J Biol Macromol</i> <b>107</b>: 2131<br /><br />Sharma A, Kumar V, Yuan H, Kanwar MK, Bhardwaj R, Thukral AK, Zheng B (2018) <br />Jasmonic Acid Seed Treatment Stimulates Insecticide Detoxification in Brassica juncea L<br /><i>Front Plant Sci</i> <b>9</b>: 1609<br /><br />Sharma A, Pachauri V, Flora SJS (2018) <br />Advances in Multi-Functional Ligands and the Need for Metal-Related Pharmacology for the Management of Alzheimer Disease<br /><i>Front Pharmacol</i> <b>9</b>: 1247<br /><br />Sharma A, Kshetrimayum C, Sadhu HG, Kumar S (2018) <br />Arsenic-induced oxidative stress, cholinesterase activity in the brain of Swiss albino mice, and its amelioration by antioxidants Vitamin E and Coenzyme Q10<br /><i>Environ Sci Pollut Res Int</i> <b>25</b>: 23946<br /><br />Chownk M, Sharma A, Singh K, Kaur J (2017) <br />mesT, a unique epoxide hydrolase, is essential for optimal growth of Mycobacterium tuberculosis in the presence of styrene oxide<br /><i>Future Microbiol</i> <b>12</b>: 527<br /><br />Kumari P, Nigam R, Singh A, Nakade UP, Sharma A, Garg SK, Singh SK (2017) <br />Demodex canis regulates cholinergic system mediated immunosuppressive pathways in canine demodicosis<br /><i>Parasitology</i> <br /><br />Sharma A, Thakur S, Kumar V, Kesavan AK, Thukral AK, Bhardwaj R (2017) <br />24-epibrassinolide stimulates imidacloprid detoxification by modulating the gene expression of Brassica juncea L<br /><i>BMC Plant Biol</i> <b>17</b>: 56<br /><br />Sharma A, Mendonca J, Ying J, Kim HS, Verdone JE, Zarif JC, Carducci M, Hammers H, Pienta KJ, Kachhap S (2017) <br />The prostate metastasis suppressor gene NDRG1 differentially regulates cell motility and invasion<br /><i>Mol Oncol</i> <b>11</b>: 655<br /><br />Sharma A, Piplani P (2017) <br />Design and synthesis of some acridine-piperazine hybrids for the improvement of cognitive dysfunction<br /><i>Chemical Biology Drug Des</i> <b>90</b>: 926<br /><br />Kumar A, Sharma A, Kaur G, Makkar P, Kaur J (2016) <br />Functional characterization of hypothetical proteins of Mycobacterium tuberculosis with possible esterase/lipase signature: A Cumulative in silico and in vitro approach<br /><i>J Biomol Struct Dyn</i> <b>35</b>: 1226<br /><br />Singh SK, Singh VK, Yadav BK, Nakade UP, Kumari P, Srivastava MK, Sharma A, Choudhary S, Swain D, Garg SK (2016) <br />Potential association of reduced cholinesterase activity with Trypanosoma evansi pathogenesis in buffaloes<br /><i>Vet Parasitol</i> <b>225</b>: 29<br /><br />Bedi JS, Gill JP, Kaur P, Sharma A, Aulakh RS (2015) <br />Evaluation of pesticide residues in human blood samples from Punjab (India)<br /><i>Vet World</i> <b>8</b>: 66<br /><br />Croessmann S, Wong HY, Zabransky DJ, Chu D, Mendonca J, Sharma A, Mohseni M, Rosen DM, Scharpf RB, Cidado J, Cochran RL, Parsons HA, Dalton WB, Erlanger B, Button B, Cravero K, Kyker-Snowman K, Beaver JA, Kachhap S, Hurley PJ, Lauring J, Park BH (2015) <br />NDRG1 links p53 with proliferation-mediated centrosome homeostasis and genome stability<br /><i>Proc Natl Acad Sci U S A</i> <b>112</b>: 11583<br /><br />Gostincar C, Ohm RA, Kogej T, Sonjak S, Turk M, Zajc J, Zalar P, Grube M, Sun H, Han J, Sharma A, Chiniquy J, Ngan CY, Lipzen A, Barry K, Grigoriev IV, Gunde-Cimerman N (2014) <br />Genome sequencing of four Aureobasidium pullulans varieties: biotechnological potential, stress tolerance, and description of new species<br /><i>BMC Genomics</i> <b>15</b>: 549<br /><br />Jiang X, Peery A, Hall AB, Sharma A, Chen XG, Waterhouse RM, Komissarov A, Riehle MM, Shouche Y, Sharakhova MV, Lawson D, Pakpour N, Arensburger P, Davidson VL, Eiglmeier K, Emrich S, George P, Kennedy RC, Mane SP, Maslen G, Oringanje C, Qi Y, Settlage R, Tojo M, Tubio JM, Unger MF, Wang B, Vernick KD, Ribeiro JM, James AA, Michel K, Riehle MA, Luckhart S, Sharakhov IV, Tu Z (2014) <br />Genome analysis of a major urban malaria vector mosquito, Anopheles stephensi<br /><i>Genome Biol</i> <b>15</b>: 459<br /><br />Khan S, Sharma A, Belrhali H, Yogavel M (2014) <br />Structural basis of malaria parasite lysyl-tRNA synthetase inhibition by cladosporin<br /><i>J Struct Funct Genomics</i> <b>15</b>: 63<br /><br />Sharma A, Shetty M, Parida A, Adiga S, Kamath S, Sowjanya (2014) <br />Effect of ethanolic extract of Acacia auriculiformis leaves on learning and memory in rats<br /><i>Pharmacognosy Res</i> <b>6</b>: 246<br /><br />Sharma A, Bemis M, Desilets AR (2014) <br />Role of Medium Chain Triglycerides (Axona(R)) in the Treatment of Mild to Moderate Alzheimer's Disease<br /><i>Am J Alzheimers Dis Other Demen</i> <b>29</b>: 409<br /><br />Joshi MN, Pandit AS, Sharma A, Pandya RV, Desai SM, Saxena AK, Bagatharia SB (2013) <br />Draft Genome Sequence of Arthrobacter crystallopoietes Strain BAB-32, Revealing Genes for Bioremediation<br /><i>Genome Announc</i> <b>1</b>: <br /><br />Joshi MN, Pandit AS, Sharma A, Pandya RV, Saxena AK, Bagatharia SB (2013) <br />Draft Genome Sequence of the Halophilic Bacterium Halobacillus sp. Strain BAB-2008<br /><i>Genome Announc</i> <b>1</b>: <br /><br />Joshi MN, Sharma A, Pandit AS, Pandya RV, Saxena AK, Bagatharia SB (2013) <br />Draft Genome Sequence of Brevibacillus sp. Strain BAB-2500, a Strain That Might Play an Important Role in Agriculture<br /><i>Genome Announc</i> <b>1</b>: e00021<br /><br />Kumar Singh A, Sangwan N, Sharma A, Gupta V, Khurana JP, Lal R (2013) <br />Draft Genome Sequence of Sphingobium quisquiliarum Strain P25T, a Novel Hexachlorocyclohexane (HCH)-Degrading Bacterium Isolated from an HCH Dumpsite<br /><i>Genome Announc</i> <b>1</b>: <br /><br />Sharma A, Piplani P (2013) <br />Acetylcholinesterase Inhibitors from QSAR Point of View: How Close are We?<br /><i>Cent Nerv Syst Agents Med Chem</i> <b>13</b>: 71<br /><br />Deb PK, Sharma A, Piplani P, Akkinepally RR (2012) <br />Molecular docking and receptor-specific 3D-QSAR studies of acetylcholinesterase inhibitors<br /><i>Mol Divers</i> <b>16</b>: 803<br /><br />Sharma A, Mishra M, Shukla AK, Kumar R, Abdin MZ, Chowdhuri DK (2012) <br />Organochlorine pesticide, endosulfan induced cellular and organismal response in Drosophila melanogaster<br /><i>J Hazard Mater</i> <b>221-222</b>: 275<br /><br />Schnable PS, Ware D, Fulton RS, Stein JC, Wei F, Pasternak S, Liang C, Zhang J, Fulton L, Graves TA, Minx P, Reily AD, Courtney L, Kruchowski SS, Tomlinson C, Strong C, Delehaunty K, Fronick C, Courtney B, Rock SM, Belter E, Du F, Kim K, Abbott RM, Cotton M, Levy A, Marchetto P, Ochoa K, Jackson SM, Gillam B, Chen W, Yan L, Higginbotham J, Cardenas M, Waligorski J, Applebaum E, Phelps L, Falcone J, Kanchi K, Thane T, Scimone A, Thane N, Henke J, Wang T, Ruppert J, Shah N, Rotter K, Hodges J, Ingenthron E, Cordes M, Kohlberg S, Sgro J, Delgado B, Mead K, Chinwalla A, Leonard S, Crouse K, Collura K, Kudrna D, Currie J, He R, Angelova A, Rajasekar S, Mueller T, Lomeli R, Scara G, Ko A, Delaney K, Wissotski M, Lopez G, Campos D, Braidotti M, Ashley E, Golser W, Kim H, Lee S, Lin J, Dujmic Z, Kim W, Talag J, Zuccolo A, Fan C, Sebastian A, Kramer M, Spiegel L, Nascimento L, Zutavern T, Miller B, Ambroise C, Muller S, Spooner W, Narechania A, Ren L, Wei S, Kumari S, Faga B, Levy MJ, McMahan L, Van Buren P, Vaughn MW, Ying K, Yeh CT, Emrich SJ, Jia Y, Kalyanaraman A, Hsia AP, Barbazuk WB, Baucom RS, Brutnell TP, Carpita NC, Chaparro C, Chia JM, Deragon JM, Estill JC, Fu Y, Jeddeloh JA, Han Y, Lee H, Li P, Lisch DR, Liu S, Liu Z, Nagel DH, McCann MC, SanMiguel P, Myers AM, Nettleton D, Nguyen J, Penning BW, Ponnala L, Schneider KL, Schwartz DC, Sharma A, Soderlund C, Springer NM, Sun Q, Wang H, Waterman M, Westerman R, Wolfgruber TK, Yang L, Yu Y, Zhang L, Zhou S, Zhu Q, Bennetzen JL, Dawe RK, Jiang J, Jiang N, Presting GG, Wessler SR, Aluru S, Martienssen RA, Clifton SW, McCombie WR, Wing RA, Wilson RK (2009) <br />The B73 maize genome: complexity, diversity, and dynamics<br /><i>Science</i> <b>326</b>: 1112<br /><br />Sharma A, Bardhan D, Patel R (2009) <br />Optimization of physical parameters for lipase production from Arthrobacter sp. BGCC#490<br /><i>Indian J Biochem Biophys</i> <b>46</b>: 178<br /><br />Shah S, Sharma A, Varandani D, Mehta B, Gupta MN (2007) <br />A high performance lipase preparation: characterization and atomic force microscopy<br /><i>J Nanosci Nanotechnol</i> <b>7</b>: 2157<br /><br />Shah S, Sharma A, Gupta MN (2006) <br />Preparation of cross-linked enzyme aggregates by using bovine serum albumin as a proteic feeder<br /><i>Analytical Biochemistry</i> <b>351</b>: 207<br /><br />Moaddel R, Sharma A, Huseni T, Jones GS, Jr., Hanson RN, Loring RH (1999) <br />Novel biotinylated phenylarsonous acids as bifunctional reagents for spatially close thiols: studies on reduced antibodies and the agonist binding site of reduced Torpedo nicotinic receptors<br /><i>Bioconjug Chem</i> <b>10</b>: 629<br /><br />Singh N, Sharma A, Singh M (1998) <br />Effects of BN-50730 (PAF receptor antagonist) and physostigmine (AChE inhibitor) on learning and memory in mice<br /><i>Methods Find Exp Clin Pharmacol</i> <b>19</b>: 585<br /><br />Sharma A, Parikh V, Singh M (1997) <br />Pharmacological basis of drug therapy of Alzheimer's disease<br /><i>Indian J Exp Biol</i> <b>35</b>: 1146<br /><br />