Behl T, Kaur I, Sehgal A, Singh S, Sharma N, Gupta S, Albratty M, Najmi A, Alhazmi HA, Bungau S (2022)
AChE as a Spark in the Alzheimer's Blaze - Antagonizing Effect of a Cyclized Variant
Ageing Res Rev

Kumar B, Dwivedi AR, Arora T, Raj K, Prashar V, Kumar V, Singh S, Prakash J (2022)
Design, Synthesis, and Pharmacological Evaluation of N-Propargylated Diphenylpyrimidines as Multitarget Directed Ligands for the Treatment of Alzheimer's Disease
ACS Chem Neurosci

Mishra G, Awasthi R, Singh AK, Singh S, Mishra SK, Singh SK, Nandi MK (2022)
Intranasally Co-administered Berberine and Curcumin Loaded in Transfersomal Vesicles Improved Inhibition of Amyloid Formation and BACE-1
ACS Omega 7: 43290

Singh A, Gupta P, Tiwari S, Mishra A, Singh S (2022)
Guanabenz mitigates the neuropathological alterations and cell death in Alzheimer's disease
Cell Tissue Research

Cf SF, Rebello S, Mathachan Aneesh E, Sindhu R, Binod P, Singh S, Pandey A (2021)
Bioprospecting of gut microflora for plastic biodegradation
Bioengineered 12: 1040

Deng L, Viray K, Singh S, Cravatt B, Stella N (2021)
ABHD6 Controls Amphetamine-Stimulated Hyperlocomotion: Involvement of CB(1) Receptors
Cannabis Cannabinoid Res

Dhami M, Raj K, Singh S (2021)
Neuroprotective Effect of Fucoxanthin against Intracerebroventricular Streptozotocin (ICV-STZ) Induced Cognitive Impairment in Experimental Rats
Curr Alzheimer Res

Gupta P, Tiwari S, Singh A, Pal A, Mishra A, Singh S (2021)
Rivastigmine attenuates the Alzheimer's disease related protein degradation and apoptotic neuronal death signaling
Biochemical Journal

Khandelwal N, Shaikh M, Mhetre A, Singh S, Sajeevan T, Joshi A, Balaji KN, Chakrapani H, Kamat SS (2021)
Fatty acid chain length drives lysophosphatidylserine-dependent immunological outputs
Cell Chemical Biology

Patel R, Kaur K, Singh S (2021)
Protective effect of andrographolide against STZ induced Alzheimer's disease in experimental rats: possible neuromodulation and Abeta((1-42)) analysis
Inflammopharmacology

Singh S, Kamat SS (2021)
The loss of enzymatic activity of the PHARC associated lipase ABHD12 results in increased phagocytosis that causes neuroinflammation
European Journal of Neuroscience

Skolnick J, Gao M, Zhou H, Singh S (2021)
AlphaFold 2: Why It Works and Its Implications for Understanding the Relationships of Protein Sequence, Structure, and Function
J Chem Inf Model

Castelli R, Scalvini L, Vacondio F, Lodola A, Anselmi M, Vezzosi S, Carmi C, Bassi M, Ferlenghi F, Rivara S, Moller IR, Rand KD, Daglian J, Wei D, Dotsey EY, Ahmed F, Jung KM, Stella N, Singh S, Mor M, Piomelli D (2020)
Benzisothiazolinone derivatives as potent allosteric monoacylglycerol lipase inhibitors that functionally mimic sulfenylation of regulatory cysteines
Journal of Medicinal Chemistry 63: 1261

Inayat S, Nazariahangarkolaee M, Singh S, McNaughton BL, Whishaw IQ, Mohajerani MH (2020)
Low acetylcholine during early sleep is important for motor memory consolidation
Sleep 43:

Sharma S, Srivastav S, Singh G, Singh S, Malik R, Alam MM, Shaqiquzamman M, Ali S, Akhter M (2020)
In silico strategies for probing novel DPP-IV inhibitors as anti-diabetic agents
J Biomol Struct Dyn

Singh S, Joshi A, Kamat SS (2020)
Mapping the neuroanatomy of ABHD16A-ABHD12 & lysophosphatidylserines provides new insights into the pathophysiology of the human neurological disorder PHARC
Biochemistry

Verma AK, Singh S, Rizvi SI (2020)
Age-dependent altered redox homeostasis in the chronodisrupted rat model and moderation by melatonin administration
Chronobiol Int

Cong S, Tian K, Zhang X, Lu F, Singh S, Prior B, Wang ZX (2019)
Synthesis of flavor esters by a novel lipase from Aspergillus niger in a soybean-solvent system
3 Biotech 9: 244

Kelkar DS, Ravikumar G, Mehendale N, Singh S, Joshi A, Sharma AK, Mhetre A, Rajendran A, Chakrapani H, Kamat SS (2019)
A chemical-genetic screen identifies ABHD12 as an oxidized-phosphatidylserine lipase
Nat Chemical Biology 15: 169

Singh AK, Singh S, Tripathi VK, Bissoyi A, Garg G, Rizvi SI (2019)
Rapamycin Confers Neuroprotection Against Aging-Induced Oxidative Stress, Mitochondrial Dysfunction, and Neurodegeneration in Old Rats Through Activation of Autophagy
Rejuvenation Res 22: 60

Tiwari RK, Singh S, Pandey RS (2019)
Assessment of acute toxicity and biochemical responses to chlorpyrifos, cypermethrin and their combination exposed earthworm, Eudrilus eugeniae
Toxicol Rep 6: 288

van Esbroeck ACM, Kantae V, Di X, van der Wel T, den Dulk H, Stevens AF, Singh S, Bakker AT, Florea BI, Stella N, Overkleeft HS, Hankemeier T, van der Stelt M (2019)
Identification of alpha,beta-Hydrolase Domain Containing Protein 6 as a Diacylglycerol Lipase in Neuro-2a Cells
Front Mol Neurosci 12: 286

Garg G, Singh S, Singh AK, Rizvi SI (2018)
N-acetyl-l-cysteine attenuates oxidative damage and neurodegeneration in rat brain during aging
Canadian Journal of Physiology & Pharmacology 96: 1189

Garg G, Singh S, Singh AK, Rizvi SI (2018)
Whey protein concentrate supplementation protects rat brain against aging-induced oxidative stress and neurodegeneration
Appl Physiol Nutr Metab 43: 437

Joshi A, Shaikh M, Singh S, Rajendran A, Mhetre A, Kamat SS (2018)
Biochemical characterization of the PHARC-associated serine hydrolase ABHD12 reveals its preference for very-long-chain lipids
Journal of Biological Chemistry 293: 16953

Singh S, Tiwari RK, Pandey RS (2018)
Evaluation of acute toxicity of triazophos and deltamethrin and their inhibitory effect on AChE activity in Channa punctatus
Toxicol Rep 5: 85

Biswas J, Gupta S, Verma DK, Gupta P, Singh A, Tiwari S, Goswami P, Sharma S, Singh S (2017)
Involvement of glucose related energy crisis and endoplasmic reticulum stress: Insinuation of streptozotocin induced Alzheimer's like pathology
Cell Signal 42: 211

Garg G, Singh S, Singh AK, Rizvi SI (2017)
Antiaging Effect of Metformin on Brain in Naturally Aged and Accelerated Senescence Model of Rat
Rejuvenation Res 20: 173

Singh AK, Garg G, Singh S, Rizvi SI (2017)
Synergistic Effect of Rapamycin and Metformin Against Age-Dependent Oxidative Stress in Rat Erythrocytes
Rejuvenation Res 20: 420

Tiwari RK, Singh S, Pandey RS (2017)
Assessment of the acute toxicity of chlorpyrifos and cypermethrin to Heteropneustes fossilis and their impact on acetylcholinesterase activity
Drug & Chemical Toxicology

Biely P, Singh S, Puchart V (2016)
Towards enzymatic breakdown of complex plant xylan structures: State of the art
Biotechnol Adv 34: 1260

Biswas J, Goswami P, Gupta S, Joshi N, Nath C, Singh S (2016)
Streptozotocin Induced Neurotoxicity Involves Alzheimer's Related Pathological Markers: a Study on N2A Cells
Molecular Neurobiology 53: 2794

Ismail T, Shafi S, Singh S, Sidiq T, Khajuria A, Rouf A, Yadav M, Saikam V, Singh PP, Alam MS, Islam N, Sharma K, Kumar HM (2016)
Synthesis and immunopotentiating activity of novel isoxazoline functionalized coumarins
Eur Journal of Medicinal Chemistry 123: 90

Jamal F, Haque QS, Singh S, Rastogi SK (2016)
The influence of organophosphate and carbamate on sperm chromatin and reproductive hormones among pesticide sprayers
Toxicol Ind Health 32: 1527

Singh S, Prakash A, Kaur S, Ming LC, Mani V, Majeed AB (2016)
The role of multifunctional drug therapy as an antidote to combat experimental subacute neurotoxicity induced by organophosphate pesticides
Environ Toxicol 31: 1017

Chatterjee M, Verma R, Kumari R, Singh S, Verma AK, Dwivedi AK, Palit G (2015)
Antipsychotic activity of standardized Bacopa extract against ketamine-induced experimental psychosis in mice: Evidence for the involvement of dopaminergic, serotonergic, and cholinergic systems
Pharm Biol 53: 1850

Dutta P, Kamath SS, Bhalla A, Shah VN, Srinivasan A, Gupta P, Singh S (2015)
Effects of acute organophosphate poisoning on pituitary target gland hormones at admission, discharge and three months after poisoning: A hospital based pilot study
Indian J Endocrinol Metab 19: 116

Aggarwal N, Arya A, Mathur D, Singh S, Tyagi A, Kumar R, Rana N, Singh R, Prasad AK (2014)
Effect of acyl chain length on selective biocatalytic deacylation on O-aryl glycosides and separation of anomers
Bioorg Chem 53: 83

Gupta N, Kandimalla R, Priyanka K, Singh G, Gill KD, Singh S (2014)
Effect of Resveratrol and Nicotine on PON1 Gene Expression: In Vitro Study
Indian J Clinical Biochemistry 29: 69

Kaur S, Singh S, Chahal KS, Prakash A (2014)
Potential pharmacological strategies for the improved treatment of organophosphate-induced neurotoxicity
Canadian Journal of Physiology & Pharmacology 92: 893

Naaz H, Singh S, Pandey VP, Singh P, Dwivedi UN (2013)
Anti-cholinergic alkaloids as potential therapeutic agents for Alzheimer's disease: an in silico approach
Indian J Biochem Biophys 50: 120

Rehvathy V, Tan MH, Gunaletchumy SP, Teh X, Wang S, Baybayan P, Singh S, Ashby M, Kaakoush NO, Mitchell HM, Croft LJ, Goh KL, Loke MF, Vadivelu J (2013)
Multiple Genome Sequences of Helicobacter pylori Strains of Diverse Disease and Antibiotic Resistance Backgrounds from Malaysia
Genome Announc 1:

Sahay H, Babu BK, Singh S, Kaushik R, Saxena AK, Arora DK (2013)
Cold-active hydrolases producing bacteria from two different sub-glacial Himalayan lakes
J Basic Microbiol 53: 703

Saxena AK, Roy KK, Singh S, Vishnoi SP, Kumar A, Kashyap VK, Kremer L, Srivastava R, Srivastava BS (2013)
Identification and characterisation of small-molecule inhibitors of Rv3097c-encoded lipase (LipY) of Mycobacterium tuberculosis that selectively inhibit growth of bacilli in hypoxia
Int J Antimicrob Agents 42: 27

Chatterjee M, Singh S, Kumari R, Verma AK, Palit G (2012)
Evaluation of the antipsychotic potential of Panax quinquefolium in ketamine induced experimental psychosis model in mice
Neurochem Res 37: 759

Goel P, Gupta N, Singh S, Bhalla A, Sharma N, Gill KD (2012)
Regeneration of Red Cell Cholinesterase Activity Following Pralidoxime (2-PAM) Infusion in First 24 h in Organophosphate Poisoned Patients
Indian J Clinical Biochemistry 27: 34

Gupta N, Binu KB, Singh S, Maturu NV, Sharma YP, Bhansali A, Gill KD (2012)
Low serum PON1 activity: an independent risk factor for coronary artery disease in North-West Indian type 2 diabetics
Gene 498: 13

Sharma RK, Singh S, Tiwari R, Mandal D, Olsen CE, Parmar VS, Parang K, Prasad AK (2012)
O-Aryl alpha,beta-d-ribofuranosides: synthesis & highly efficient biocatalytic separation of anomers and evaluation of their Src kinase inhibitory activity
Bioorganic & Medicinal Chemistry 20: 6821

Singh S, Kumar V, Singh P, Banerjee BD, Rautela RS, Grover SS, Rawat DS, Pasha ST, Jain SK, Rai A (2012)
Influence of CYP2C9, GSTM1, GSTT1 and NAT2 genetic polymorphisms on DNA damage in workers occupationally exposed to organophosphate pesticides
Mutat Res 741: 101

Gupta N, Binukumar BK, Singh S, Sunkaria A, Kandimalla R, Bhansali A, Gill KD (2011)
Serum paraoxonase-1 (PON1) activities (PONase/AREase) and polymorphisms in patients with type 2 diabetes mellitus in a North-West Indian population
Gene 487: 88

Gupta N, Singh S, Maturu VN, Sharma YP, Gill KD (2011)
Paraoxonase 1 (PON1) polymorphisms, haplotypes and activity in predicting cad risk in North-West Indian Punjabis
PLoS ONE 6: e17805

Singh S, Kumar V, Thakur S, Banerjee BD, Rautela RS, Grover SS, Rawat DS, Pasha ST, Jain SK, Ichhpujani RL, Rai A (2011)
Paraoxonase-1 genetic polymorphisms and susceptibility to DNA damage in workers occupationally exposed to organophosphate pesticides
Toxicol Appl Pharmacol 252: 130

Singh S, Kumar V, Singh P, Thakur S, Banerjee BD, Rautela RS, Grover SS, Rawat DS, Pasha ST, Jain SK, Rai A (2011)
Genetic polymorphisms of GSTM1, GSTT1 and GSTP1 and susceptibility to DNA damage in workers occupationally exposed to organophosphate pesticides
Mutat Res 725: 36

Singh S, Kumar V, Thakur S, Banerjee BD, Chandna S, Rautela RS, Grover SS, Rawat DS, Pasha ST, Jain SK, Ichhpujani RL, Rai A (2011)
DNA damage and cholinesterase activity in occupational workers exposed to pesticides
Environ Toxicol Pharmacol 31: 278

Singh S, Roy S, Sethi S, Benjamin B, Sundaram S, Khanna V, Kandalkar SR, Pal C, Kant R, Patra AK, Rayasam G, Mittra S, Saini KS, Paliwal J, Chugh A, Ahmed S, Sattigeri J, Cliff I, Ray A, Bansal VS, Bhatnagar PK, Davis JA (2011)
RBx-0597, a potent, selective and slow-binding inhibitor of dipeptidyl peptidase-IV for the treatment of type 2 diabetes
European Journal of Pharmacology 652: 157

Davis JA, Singh S, Sethi S, Roy S, Mittra S, Rayasam G, Bansal V, Sattigeri J, Ray A (2010)
Nature of action of Sitagliptin, the dipeptidyl peptidase-IV inhibitor in diabetic animals
Indian J Pharmacol 42: 229

Denoeud F, Henriet S, Mungpakdee S, Aury JM, Da Silva C, Brinkmann H, Mikhaleva J, Olsen LC, Jubin C, Canestro C, Bouquet JM, Danks G, Poulain J, Campsteijn C, Adamski M, Cross I, Yadetie F, Muffato M, Louis A, Butcher S, Tsagkogeorga G, Konrad A, Singh S, Jensen MF, Huynh Cong E, Eikeseth-Otteraa H, Noel B, Anthouard V, Porcel BM, Kachouri-Lafond R, Nishino A, Ugolini M, Chourrout P, Nishida H, Aasland R, Huzurbazar S, Westhof E, Delsuc F, Lehrach H, Reinhardt R, Weissenbach J, Roy SW, Artiguenave F, Postlethwait JH, Manak JR, Thompson EM, Jaillon O, Du Pasquier L, Boudinot P, Liberles DA, Volff JN, Philippe H, Lenhard B, Roest Crollius H, Wincker P, Chourrout D (2010)
Plasticity of animal genome architecture unmasked by rapid evolution of a pelagic tunicate
Science 330: 1381

Li SS, Yu SL, Singh S (2010)
Epigenetic states and expression of imprinted genes in human embryonic stem cells
World J Stem Cells 2: 97

Gupta N, Gill K, Singh S (2009)
Paraoxonases: structure, gene polymorphism & role in coronary artery disease
Indian J Med Res 130: 361

Liang GB, Qian X, Biftu T, Singh S, Gao YD, Scapin G, Patel S, Leiting B, Patel R, Wu J, Zhang X, Thornberry NA, Weber AE (2008)
Discovery of new binding elements in DPP-4 inhibition and their applications in novel DPP-4 inhibitor design
Bioorganic & Medicinal Chemistry Lett 18: 3706

Sattigeri JA, Andappan MM, Kishore K, Thangathirupathy S, Sundaram S, Singh S, Sharma S, Davis JA, Chugh A, Bansal VS (2008)
Discovery of conformationally rigid 3-azabicyclo[3.1.0]hexane-derived dipeptidyl peptidase-IV inhibitors
Bioorganic & Medicinal Chemistry Lett 18: 4087

Biftu T, Feng D, Qian X, Liang GB, Kieczykowski G, Eiermann G, He H, Leiting B, Lyons K, Petrov A, Sinha-Roy R, Zhang B, Scapin G, Patel S, Gao YD, Singh S, Wu J, Zhang X, Thornberry NA, Weber AE (2007)
(3R)-4-[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(2,2,2-trifluoroethyl)- 1,4-diazepan-2-one, a selective dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
Bioorganic & Medicinal Chemistry Lett 17: 49

Biftu T, Scapin G, Singh S, Feng D, Becker JW, Eiermann G, He H, Lyons K, Patel S, Petrov A, Sinha-Roy R, Zhang B, Wu J, Zhang X, Doss GA, Thornberry NA, Weber AE (2007)
Rational design of a novel, potent, and orally bioavailable cyclohexylamine DPP-4 inhibitor by application of molecular modeling and X-ray crystallography of sitagliptin
Bioorganic & Medicinal Chemistry Lett 17: 3384

Roy S, Khanna V, Mittra S, Dhar A, Singh S, Mahajan DC, Priyadarsiny P, Davis JA, Sattigeri J, Saini KS, Bansal VS (2007)
Combination of dipeptidylpeptidase IV inhibitor and low dose thiazolidinedione: preclinical efficacy and safety in db/db mice
Life Sciences 81: 72

Saxena G, Singh SP, Pal R, Singh S, Pratap R, Nath C (2007)
Gugulipid, an extract of Commiphora whighitii with lipid-lowering properties, has protective effects against streptozotocin-induced memory deficits in mice
Pharmacol Biochem Behav 86: 797

Singh S, Bhardwaj U, Verma SK, Bhalla A, Gill K (2007)
Hyperamylasemia and acute pancreatitis following anticholinesterase poisoning
Hum Exp Toxicol 26: 467

Singh S, Kaur G, Chakraborti AK, Jain RK, Banerjee UC (2006)
Study of the experimental conditions for the lipase production by a newly isolated strain of Pseudomonas aeruginosa for the enantioselective hydrolysis of (+/-)-methyl trans-3(4-methoxyphenyl) glycidate
Bioprocess Biosyst Eng 28: 341

Eddleston M, Singh S, Buckley N (2004)
Organophosphorus poisoning (acute)
Clin Evid

Panda S, Goyal V, Behari M, Singh S, Srivastava T (2004)
Myasthenic crisis: a retrospective study
Neurol India 52: 453

Tripathi SM, Singh VK, Singh S, Singh DK (2004)
Enzyme inhibition by the molluscicidal agent Punica granatum Linn. bark and Canna indica Linn. root
Phytother Res 18: 501

Singh S, Parthasarathy S, Sud A, Wanchu A, Bambery P (2003)
Acute pancreatitis following propoxyfur (Baygon) ingestion
J Assoc Physicians India 51: 78

Das A, Shanker G, Nath C, Pal R, Singh S, Singh H (2002)
A comparative study in rodents of standardized extracts of Bacopa monniera and Ginkgo biloba. Anticholinesterase and cognitive enhancing activities
Pharmacol Biochem Behav 73: 893

Khotianov N, Singh R, Singh S (2002)
Lewy body dementia: case report and discussion
J Am Board Fam Pract 15: 50

Singh S, Chaudhry D, Behera D, Gupta D, Jindal SK (2001)
Aggressive atropinisation and continuous pralidoxime (2-PAM) infusion in patients with severe organophosphate poisoning: experience of a northwest Indian hospital
Hum Exp Toxicol 20: 15

Prior C, Singh S (2000)
Factors influencing the low-frequency associated nicotinic ACh autoreceptor-mediated depression of ACh release from rat motor nerve terminals
British Journal of Pharmacology 129: 1067

Singh S, Nain CK, Verma M, Leelamma CO, Goel RC (2000)
Aspirin esterases in North-West Indians: the influence of age and nutrition
Int J Clinical Pharmacology & Therapeutics 38: 315

Singh VK, Singh S, Singh DK (1999)
Effect of active molluscicidal component of spices on different enzyme activities and biogenic amine levels in the nervous tissue of Lymnaea acuminata
Phytother Res 13: 649

Singh S, Prior C (1998)
Prejunctional effects of the nicotinic ACh receptor agonist dimethylphenylpiperazinium at the rat neuromuscular junction
The Journal of Physiology 511 ( Pt 2): 451

Kraliz D, Singh S (1997)
Selective blockade of the delayed rectifier potassium current by tacrine in Drosophila
Journal of Neurobiology 32: 1

Singh S, Gupta J (1991)
Some physicochemical properties of human milk bile-salt activated lipase
Indian J Biochem Biophys 28: 155

Baveja SK, Singh S (1987)
Thin-layer chromatographic examination of the degradation of centbucridine in aqueous solutions
Journal of Chromatography 396: 337

Singh S, Sareen KN, Goedde HW (1974)
Investigation of some biochemical genetic markers in four endogamous groups from Panjab (N. W. India). I. Protein and enzyme polymorphisms in serum
Humangenetik 21: 341

Singh S, Saternus K, Munsch H, Altland K, Goedde HW, Eriksson AW (1974)
Pseudocholinesterase polymorphism among alanders (Finno-Swedes), maris (Cheremisses, USSR) and greenland eskimos, and the segregation of some E1 and E2 locus types in Finnish Lapp Families
Hum Hered 24: 352

Goedde HW, Hirth L, Benkmann HG, Pellicer A, Pellicer T, Stahn M, Singh S (1973)
Population genetic studies of serum protein polymorphisms in four Spanish populations. II
Hum Hered 23: 135

Goedde HW, Benkmann HG, Singh S, Das BM, Chakravartti MR, Delbruck H, Flatz G (1972)
Genetic survey in the population of Assam. II. Serum protein and erythrocyte enzyme polymorphisms
Hum Hered 22: 331

Goedde HW, Hirth L, Benkmann HG, Singh S, Wendt GG (1972)
Family studies on the third component of complement (C3), 1-antitrypsin and pseudocholinesterase polymorphism (locus E 1 and E 2 ) in the area of Marburg (Germany)
Humangenetik 17: 85

Singh S, Amma MK, Sareen KN, Goedde HW (1971)
A study of the pseudocholinesterase polymorphism among a panjabi population
Hum Hered 21: 388

Singh S, Jensen M, Goedde HW, Lehmann W, Pyorala K, Eriksson AW (1971)
Pseudocholinesterase polymorphism among Lapp populations in Finland
Humangenetik 12: 131