Houngbedji NH, Stepankova S, Pflegr V, Svrckova K, Svarcova M, Vinsova J, Kratky M (2023) <br />Novel Inhibitors of Acetyl- and Butyrylcholinesterase Derived from Benzohydrazides: Synthesis, Evaluation and Docking Study<br /><i>Pharmaceuticals (Basel)</i> <b>16</b>: <br /><br />Sachleviciute U, Gonzalez G, Kvasnicova M, Stepankova S, Kleizien N, Bieliauskas A, Zatloukal M, Strnad M, Slok FA, Kvasnica M, Sackus A, zukauskait A (2023) <br />Synthesis and neuroprotective activity of 3-aryl-3-azetidinyl acetic acid methyl ester derivatives<br /><i>Arch Pharm (Weinheim)</i> <br /><br />Gonzalez G, Kvasnica M, Svrckova K, Stepankova S, Santos JRC, Perina M, Jorda R, Lopes SMM, Melo T (2022) <br />Ring-fused 3beta-acetoxyandrost-5-enes as novel neuroprotective agents with cholinesterase inhibitory properties<br /><i>J Steroid Biochem Mol Biol</i> <br /><br />Pflegr V, Stepankova S, Svrckova K, Svarcova M, Vinsova J, Kratky M (2022) <br />5-Aryl-1,3,4-oxadiazol-2-amines Decorated with Long Alkyl and Their Analogues: Synthesis, Acetyl- and Butyrylcholinesterase Inhibition and Docking Study<br /><i>Pharmaceuticals (Basel)</i> <b>15</b>: 400<br /><br />Kos J, Kozik V, Pindjakova D, Jankech T, Smolinski A, Stepankova S, Hosek J, Oravec M, Jampilek J, Bak A (2021) <br />Synthesis and Hybrid SAR Property Modeling of Novel Cholinesterase Inhibitors<br /><i>Int J Mol Sci</i> <b>22</b>: <br /><br />Kratky M, Vu QA, Stepankova S, Maruca A, Silva TB, Ambroz M, Pflegr V, Rocca R, Svrckova K, Alcaro S, Borges F, Vinsova J (2021) <br />Novel propargylamine-based inhibitors of cholinesterases and monoamine oxidases: Synthesis, biological evaluation and docking study<br /><i>Bioorg Chem</i> <b>116</b>: 105301<br /><br />Kratky M, Stepankova S, Konecna K, Svrckova K, Maixnerova J, Svarcova M, Janourek O, Trejtnar F, Vinsova J (2021) <br />Novel Aminoguanidine Hydrazone Analogues: From Potential Antimicrobial Agents to Potent Cholinesterase Inhibitors<br /><i>Pharmaceuticals (Basel)</i> <b>14</b>: <br /><br />Magar P, Parravicini O, Stepankova S, Svrckova K, Garro AD, Jendrzejewska I, Pauk K, Hosek J, Jampilek J, Enriz RD, Imramovsky A (2021) <br />Novel Sulfonamide-Based Carbamates as Selective Inhibitors of BChE<br /><i>Int J Mol Sci</i> <b>22</b>: <br /><br />Kielczewska U, Jorda R, Gonzalez G, Morzycki JW, Ajani H, Svrckova K, Stepankova S, Wojtkielewicz A (2020) <br />The synthesis and cholinesterase inhibitory activities of solasodine analogues with seven-membered F ring<br /><i>J Steroid Biochem Mol Biol</i> <br /><br />Kratky M, Baranyai Z, Stepankova S, Svrckova K, Svarcova M, Stolarikova J, Horvath L, Bosze S, Vinsova J (2020) <br />N-Alkyl-2-[4-(trifluoromethyl)benzoyl]hydrazine-1-carboxamides and Their Analogues: Synthesis and Multitarget Biological Activity<br /><i>Molecules</i> <b>25</b>: <br /><br />Kratky M, Jaklova K, Stepankova S, Svrckova K, Pflegr V, Vinsova J (2020) <br />N-[3,5-Bis(trifluoromethyl)phenyl]-5-bromo-2-hydroxybenzamide Analogues: Novel Acetyl- and Butyrylcholinesterase Inhibitors<br /><i>Curr Top Med Chem</i> <b>20</b>: 2094<br /><br />Kratky M, Stepankova S, Brablikova M, Svrckova K, Svarcova M, Vinsova J (2020) <br />Novel Iodinated Hydrazide-hydrazones and their Analogues as Acetyl- and Butyrylcholinesterase Inhibitors<br /><i>Curr Top Med Chem</i> <b>20</b>: 2106<br /><br />Bak A, Kozik V, Kozakiewicz D, Gajcy K, Strub DJ, Swietlicka A, Stepankova S, Imramovsky A, Polanski J, Smolinski A, Jampilek J (2019) <br />Novel Benzene-Based Carbamates for AChE/BChE Inhibition: Synthesis and Ligand/Structure-Oriented SAR Study<br /><i>Int J Mol Sci</i> <b>20</b>: 1524<br /><br />Chlebek J, Korabecny J, Dolezal R, Stepankova S, Perez DI, Hostalkova A, Opletal L, Cahlikova L, Macakova K, Kucera T, Hrabinova M, Jun D (2019) <br />In Vitro and In Silico Acetylcholinesterase Inhibitory Activity of Thalictricavine and Canadine and Their Predicted Penetration across the Blood-Brain Barrier<br /><i>Molecules</i> <b>24</b>: <br /><br />Kratky M, Stepankova S, Houngbedji NH, Vosatka R, Vorcakova K, Vinsova J (2019) <br />2-Hydroxy-N-phenylbenzamides and Their Esters Inhibit Acetylcholinesterase and Butyrylcholinesterase<br /><i>Biomolecules</i> <b>9</b>: <br /><br />Kratky M, Stepankova S, Vorcakova K, Vinsova J (2018) <br />Investigation of salicylanilide and 4-chlorophenol-based N-monosubstituted carbamates as potential inhibitors of acetyl- and butyrylcholinesterase<br /><i>Bioorg Chem</i> <b>80</b>: 668<br /><br />Vorcakova K, Majekova M, Horakova E, Drabina P, Sedlak M, Stepankova S (2018) <br />Synthesis and characterization of new inhibitors of cholinesterases based on N-phenylcarbamates: In vitro study of inhibitory effect, type of inhibition, lipophilicity and molecular docking<br /><i>Bioorg Chem</i> <b>78</b>: 280<br /><br />Kratky M, Stepankova S, Vorcakova K, Navratilova L, Trejtnar F, Stolarikova J, Vinsova J (2017) <br />Synthesis of readily available fluorophenylalanine derivatives and investigation of their biological activity<br /><i>Bioorg Chem</i> <b>71</b>: 244<br /><br />Pizova H, Havelkova M, Stepankova S, Bak A, Kauerova T, Kozik V, Oravec M, Imramovsky A, Kollar P, Bobal P, Jampilek J (2017) <br />Proline-Based Carbamates as Cholinesterase Inhibitors<br /><i>Molecules</i> <b>22</b>: <br /><br />Horakova E, Drabina P, Broz B, Stepankova S, Vorcakova K, Kralovec K, Havelek R, Sedlak M (2016) <br />Synthesis, characterization and in vitro evaluation of substituted N-(2-phenylcyclopropyl)carbamates as acetyl- and butyrylcholinesterase inhibitors<br /><i>J Enzyme Inhib Med Chem</i> <br /><br />Kratky M, Stepankova S, Vorcakova K, Svarcova M, Vinsova J (2016) <br />Novel Cholinesterase Inhibitors Based on O-Aromatic N,N-Disubstituted Carbamates and Thiocarbamates<br /><i>Molecules</i> <b>21</b>: <br /><br />Kratky M, Stepankova S, Vorcakova K, Vinsova J (2016) <br />Synthesis and in vitro evaluation of novel rhodanine derivatives as potential cholinesterase inhibitors<br /><i>Bioorg Chem</i> <b>68</b>: 23<br /><br />Pejchal V, Stepankova S, Pejchalova M, Kralovec K, Havelek R, Ruzickova Z, Ajani H, Lo R, Lepsik M (2016) <br />Synthesis, structural characterization, docking, lipophilicity and cytotoxicity of 1-[(1R)-1-(6-fluoro-1,3-benzothiazol-2-yl)ethyl]-3-alkyl carbamates, novel acetylcholinesterase and butyrylcholinesterase pseudo-irreversible inhibitors<br /><i>Bioorganic & Medicinal Chemistry</i> <b>24</b>: 1560<br /><br />Stepankova S, Vorcakova K (2016) <br />Cholinesterase-based biosensors<br /><i>J Enzyme Inhib Med Chem</i> <br /><br />Cahlikova L, Perez DI, Stepankova S, Chlebek J, Safratova M, Host'alkova A, Opletal L (2015) <br />In Vitro Inhibitory Effects of 8-O-Demethylmaritidine and Undulatine on Acetylcholinesterase and Their Predicted Penetration across the Blood-Brain Barrier<br /><i>Journal of Natural Products</i> <b>78</b>: 1189<br /><br />Havlasova J, Safratova M, Siatka T, Stepankova S, Novak Z, Locarek M, Opletal L, Hrabinova M, Jun D, Benesova N, Kunes J, Cahlikova L (2014) <br />Chemical composition of bioactive alkaloid extracts from some Narcissus species and varieties and their biological activity<br /><i>Nat Prod Commun</i> <b>9</b>: 1151<br /><br />Kratky M, Stepankova S, Vorcakova K, Vinsova J (2014) <br />Salicylanilide diethyl phosphates as cholinesterases inhibitors<br /><i>Bioorg Chem</i> <b>58C</b>: 48<br /><br />Vinsova J, Kratky M, Komloova M, Dadapeer E, Stepankova S, Vorcakova K, Stolarikova J (2014) <br />Diethyl 2-(Phenylcarbamoyl)phenyl Phosphorothioates: Synthesis, Antimycobacterial Activity and Cholinesterase Inhibition<br /><i>Molecules</i> <b>19</b>: 7152<br /><br />Imramovsky A, Pejchal V, Stepankova S, Vorcakova K, Jampilek J, Vanco J, Simunek P, Kralovec K, Bruckova L, Mandikova J, Trejtnar F (2013) <br />Synthesis and in vitro evaluation of new derivatives of 2-substituted-6-fluorobenzo[d]thiazoles as cholinesterase inhibitors<br /><i>Bioorganic & Medicinal Chemistry</i> <b>21</b>: 1735<br /><br />Kovarova M, Komers K, Stepankova S, Parik P, Cegan A (2013) <br />New method for the determination of the half inhibition concentration (IC50) of cholinesterase inhibitors<br /><i>Z Naturforsch C</i> <b>68</b>: 133<br /><br />Imramovsky A, Stepankova S, Vanco J, Pauk K, Monreal-Ferriz J, Vinsova J, Jampilek J (2012) <br />Acetylcholinesterase-inhibiting activity of salicylanilide N-alkylcarbamates and their molecular docking<br /><i>Molecules</i> <b>17</b>: 10142<br /><br />Pejchal V, Stepankova S, Padelkova Z, Imramovsky A, Jampilek J (2011) <br />1,3-substituted imidazolidine-2,4,5-triones: synthesis and inhibition of cholinergic enzymes<br /><i>Molecules</i> <b>16</b>: 7565<br /><br />Kovarova M, Komers K, Stepankova S, Cegan A (2010) <br />Inhibition of acetylcholinesterase by 14 achiral and five chiral imidazole derivates<br /><i>Bioresour Technol</i> <b>101</b>: 6281<br /><br />Komersova A, Masopustova M, Komers K, Stepankova S, Cegan A (2007) <br />In vitro inhibition of cholinesterases by carbamates--a kinetic study<br /><i>Z Naturforsch C</i> <b>62</b>: 305<br /><br />Stepankova S, Komers K, Komersova A, Masopustova M, Cegan A (2007) <br />Inhibition of cholinesterase by dialkylcarbamates<br /><i>Z Naturforsch C</i> <b>62</b>: 308<br /><br />Zdrazilova P, Stepankova S, Komersova A, Vranova M, Komers K, Cegan A (2006) <br />Kinetics of 13 new cholinesterase inhibitors<br /><i>Z Naturforsch C</i> <b>61</b>: 611<br /><br />Zdrazilova P, Stepankova S, Vranova M, Komers K, Komersova A, Cegan A (2006) <br />Kinetics of total enzymatic hydrolysis of acetylcholine and acetylthiocholine<br /><i>Z Naturforsch C</i> <b>61</b>: 289<br /><br />Stepankova S, Vranova M, Zdrazilova P, Komers K, Komersova A, Cegan A (2005) <br />Two new methods monitoring kinetics of hydrolysis of acetylcholine and acetylthiocholine<br /><i>Z Naturforsch C</i> <b>60</b>: 943<br /><br />Zdrazilova P, Stepankova S, Komers K, Ventura K, Cegan A (2004) <br />Half-inhibition concentrations of new cholinesterase inhibitors<br /><i>Z Naturforsch C</i> <b>59</b>: 293<br /><br />