Cao Y, Zhang Y, Jia Z, Jia H, Sun Y, Yuan H, Bian Y, Xu B, Fu J, Qin F (2023) <br />Theaflavin-3,3'-digallate ameliorates learning and memory impairments in mice with premature brain aging induced by D-galactose<br /><i>Physiol Behav</i> <br /><br />Bai X, Sun Y, Li Y, Li M, Cao Z, Huang Z, Zhang F, Yan P, Wang L, Luo J, Wu J, Fan D, Chen H, Zhi M, Lan P, Zeng Z, Wu X, Miao Y, Zuo T (2022) <br />Landscape of the gut archaeome in association with geography, ethnicity, urbanization, and diet in the Chinese population<br /><i>Microbiome</i> <b>10</b>: 147<br /><br />Dai R, Sun Y, Su R, Gao H (2022) <br />Anti-Alzheimer's disease potential of traditional chinese medicinal herbs as inhibitors of BACE1 and AChE enzymes<br /><i>Biomed Pharmacother</i> <b>154</b>: 113576<br /><br />Huang S, Jia A, Song W, Hessler G, Meng Y, Sun Y, Xu L, Laessle H, Jirschitzka J, Ma S, Xiao Y, Yu D, Hou J, Liu R, Sun H, Liu X, Han Z, Chang J, Parker JE, Chai J (2022) <br />Identification and receptor mechanism of TIR-catalyzed small molecules in plant immunity<br /><i>Science</i> <br /><br />Li H, Perino A, Huang Q, Von Alvensleben GVG, Banaei-Esfahani A, Velazquez-Villegas LA, Gariani K, Korbelius M, Bou Sleiman M, Imbach J, Sun Y, Li X, Bachmann A, Goeminne LJE, Gallart-Ayala H, Williams EG, Ivanisevic J, Auwerx J, Schoonjans K (2022) <br />Integrative systems analysis identifies genetic and dietary modulators of bile acid homeostasis<br /><i>Cell Metab</i> <br /><br />Li X, Li T, Zhang P, Lu L, Sun Y, Zhang B, Allen S, White L, Phillips J, Zhu Z, Yao H, Xu J (2022) <br />Discovery of novel hybrids containing clioquinol-1-benzyl-1,2,3,6-tetrahydropyridine as multi-target-directed ligands (MTDLs) against Alzheimer's disease<br /><i>Eur Journal of Medicinal Chemistry</i> <b>244</b>: 114841<br /><br />Liang M, Ma L, Li X, Feng D, Zhang J, Sun Y (2022) <br />Identification and characterization of two types of triacylglycerol lipase genes from Neocaridina denticulata sinensis<br /><i>Fish Shellfish Immunol</i> <br /><br />Suo H, Geng X, Sun Y, Zhang L, Yang J, Yang F, Yan H, Hu Y, Xu L (2022) <br />Surface Modification of Magnetic ZIF-90 Nanoparticles Improves the Microenvironment of Immobilized Lipase and Its Application in Esterification<br /><i>Langmuir</i> <br /><br />Tian Y, Li S, Yang P, Su X, Liu J, Lv X, Dong K, Yang T, Duan M, Hu G, Yue H, Sun Y, Zhang H, Du Z, Miao Z, Tong M, Hou Y, Gao Z, Zhao Y (2022) <br />Synthesis and biological evaluation of new series of benzamide derivatives containing urea moiety as sEH inhibitors<br /><i>Bioorganic & Medicinal Chemistry Lett</i> <b>70</b>: 128805<br /><br />Tian Y, Li S, Dong K, Su X, Fu S, Lv X, Duan M, Yang T, Han Y, Hu G, Liu J, Sun Y, Yue H, Zhang H, Du Z, Miao Z, Tong M, Liu Y, Qin M, Gong P, Hou Y, Gao Z, Zhao Y (2022) <br />Discovery of benzamide derivatives containing urea moiety as soluble epoxide hydrolase inhibitors<br /><i>Bioorg Chem</i> <b>127</b>: 105898<br /><br />Xia DD, Duan HJ, Xie F, Xie TP, Zhang Y, Sun Y, Lu JM, Gao YH, Zhou H, Ding ZT (2022) <br />Altereporenes A-E, five epoxy octa-hydronaphthalene polyketides produced by an endophytic fungus Alternaria sp. YUD20002<br /><i>RSC Adv</i> <b>12</b>: 22295<br /><br />Xu YX, Wang C, Li XD, Guo WL, Liu GY, Zhang HB, Sun Y, Zhu DF, Xu Q (2022) <br />Activation of cholinergic basal forebrain neurons improved cognitive functions in adult-onset hypothyroid mice<br /><i>Biomed Pharmacother</i> <b>153</b>: 113495<br /><br />Gao H, Jiang Y, Zhan J, Sun Y (2021) <br />Pharmacophore-based drug design of AChE and BChE dual inhibitors as potential anti-Alzheimer's disease agents<br /><i>Bioorg Chem</i> <b>114</b>: 105149<br /><br />Geng H, Wang S, Jin Y, Cheng N, Song B, Shu S, Li B, Han Y, Gao L, Ding Z, Xu Y, Wang X, Ma Z, Sun Y (2021) <br />Nutritional Status and Body Composition in Wilson Disease: A Cross-Sectional Study From China<br /><i>Front Nutr</i> <b>8</b>: 790520<br /><br />Guo WY, Fu YX, Liu SY, Mei LC, Sun Y, Yin J, Yang WC, Yang GF (2021) <br />Multienzyme-Targeted Fluorescent Probe as a Biosensing Platform for Broad Detection of Pesticide Residues<br /><i>Analytical Chemistry</i> <br /><br />Issotina Zibrila A, Wang Z, Ali MA, Osei JA, Sun Y, Zafar S, Liu K, Li C, Kang Y, Liu J (2021) <br />Pyridostigmine ameliorates preeclamptic features in pregnant rats by inhibiting tumour necrosis factor-alpha synthetsis and antagonizing tumour necrosis factor-alpha-related effects<br /><i>J Hypertens</i> <br /><br />Liu S, Sun Y, Zhao R, Wang Y, Zhang W, Pang W (2021) <br />Isoleucine increases muscle mass through promoting myogenesis and intramyocellular fat deposition<br /><i>Food Funct</i> <b>12</b>: 144<br /><br />Sun Y, Yang Y, Zhang Z, Li Y, Hu Y, Wang N (2021) <br />Early enteral nutrition combined with PSS-based nursing in the treatment of organophosphorus pesticide poisoning<br /><i>Am J Transl Res</i> <b>13</b>: 9315<br /><br />Zhang G, Sun Y, Wu ZS, Huang X (2021) <br />Clinical Relevance and Prognostic Value of the Neuronal Protein Neuroligin 2 in Breast Cancer<br /><i>Front Oncol</i> <b>11</b>: 630257<br /><br />de Vries L, Brouckaert M, Chanoca A, Kim H, Regner MR, Timokhin VI, Sun Y, De Meester B, Van Doorsselaere J, Goeminne G, Chiang VL, Wang JP, Ralph J, Morreel K, Vanholme R, Boerjan W (2021) <br />CRISPR-Cas9 Editing of CAFFEOYL SHIKIMATE ESTERASE 1 and 2 Shows Their Importance and Partial Redundancy in Lignification in Populus tremula x P. alba<br /><i>Plant Biotechnol J</i> <br /><br />Guan GY, Wei N, Song T, Zhao C, Sun Y, Pan RX, Zhang LL, Xu YY, Dai YM, Han H (2020) <br />miR-448-3p alleviates diabetic vascular dysfunction by inhibiting endothelial-mesenchymal transition through DPP-4 dysregulation<br /><i>Journal of Cellular Physiology</i> <b>235</b>: 10024<br /><br />Han Y, Huang D, Xu S, Li L, Tian Y, Li S, Chen C, Li Y, Sun Y, Hou Y, Qin M, Gong P, Gao Z, Zhao Y (2020) <br />Ligand-based optimization to identify novel 2-aminobenzo[d]thiazole derivatives as potent sEH inhibitors with anti-inflammatory effects<br /><i>Eur Journal of Medicinal Chemistry</i> <br /><br />Li Q, Xing S, Chen Y, Liao Q, Liu Y, He S, Feng F, Zhang J, Liu W, Guo Q, Sun Y, Sun H (2020) <br />Reasonably activating Nrf2: A long-term, effective and controllable strategy for neurodegenerative diseases<br /><i>Eur Journal of Medicinal Chemistry</i> <b>185</b>: 111862<br /><br />Liu F, Ji Y, Li G, Xu C, Sun Y (2020) <br />Identification of Oliver-McFarlane syndrome caused by novel compound heterozygous variants of PNPLA6<br /><i>Gene</i> <br /><br />Liu SY, Qu RY, Li RR, Yan YC, Sun Y, Yang WC, Yang GF (2020) <br />An Activity-Based Fluorogenic Probe Enables Cellular and in Vivo Profiling of Carboxylesterase Isozymes<br /><i>Analytical Chemistry</i> <b>92</b>: 9205<br /><br />Sun Y, Wang J, Hao K (2020) <br />A Pharmacokinetic and Pharmacodynamic Evaluation of the Anti-Hepatocellular Carcinoma Compound 4-N-Carbobenzoxy-gemcitabine (Cbz-dFdC)<br /><i>Molecules</i> <b>25</b>: <br /><br />Sun Y, Zhao Z, Li Q, Wang C, Ge X, Wang X, Wang G, Qin Y (2020) <br />Dl-3-n-butylphthalide regulates cholinergic dysfunction in chronic cerebral hypoperfusion rats<br /><i>J Internal Medicine Res</i> <b>48</b>: 300060520936177<br /><br />Sun Y, Xiong P, Tang J, Zeng Z, Tang D (2020) <br />Ultrasensitive split-type electrochemical sensing platform for sensitive determination of organophosphorus pesticides based on MnO(2) nanoflower-electron mediator as a signal transduction system<br /><i>Anal Bioanal Chem</i> <b>412</b>: 6939<br /><br />Tang J, Li J, Xiong P, Sun Y, Zeng Z, Tian X, Tang D (2020) <br />Rolling circle amplification promoted magneto-controlled photoelectrochemical biosensor for organophosphorus pesticides based on dissolution of core-shell MnO(2) nanoflower@CdS mediated by butyrylcholinesterase<br /><i>Mikrochim Acta</i> <b>187</b>: 450<br /><br />Wu J, Zhao Y, Fan Z, Chen Q, Chen J, Sun Y, Jiang X, Xiao Q (2020) <br />Soluble epoxide hydrolase inhibitor protects against blood-brain barrier dysfunction in a mouse model of type 2 diabetes via the AMPK/HO-1 pathway<br /><i>Biochemical & Biophysical Research Communications</i> <br /><br />Zhang Y, Sun L, Sun Y, Chen Y, Wang X, Xu M, Chi P, Xu Z, Lu X (2020) <br />Overexpressed CES2 has prognostic value in CRC and knockdown CES2 reverses L-OHP-resistance in CRC cells by inhibition of the PI3K signaling pathway<br /><i>Experimental Cell Research</i> <br /><br />Zhang Y, Jiang W, Lv K, Sun Y, Gao X, Zhao Q, Ren W, Wang F, Liu J (2020) <br />Optimization of chemoenzymatic Baeyer-Villiger oxidation of cyclohexanone to sigma-caprolactone using response surface methodology<br /><i>Biotechnol Prog</i> <b>36</b>: e2901<br /><br />Zhou Q, Sun Y (2020) <br />Circular RNA cMras Suppresses the Progression of Lung Adenocarcinoma Through ABHD5/ATGL Axis Using NF-B Signaling Pathway<br /><i>Cancer Biother Radiopharm</i> <br /><br />Zhu X, Yang L, He Y, Sun Y, Shi W, Ou C (2020) <br />Liver Function of Male Rats Exposed to Manganese at Different Time Points<br /><i>Biol Trace Elem Res</i> <br /><br />Cui CC, Sun Y, Wang XY, Zhang Y, Xing Y (2019) <br />The effect of anti-dementia drugs on Alzheimer disease-induced cognitive impairment: A network meta-analysis<br /><i>Medicine (Baltimore)</i> <b>98</b>: e16091<br /><br />Hong R, Sun Y, Su L, Gu L, Wang F, Wu J (2019) <br />High-level expression of Humicola insolens cutinase in Pichia pastoris without carbon starvation and its use in cotton fabric bioscouring<br /><i>J Biotechnol</i> <b>304</b>: 10<br /><br />Li Y, Zhou X, Zhang Q, Chen E, Sun Y, Ye D, Wang O, Zhang X, Lyu J (2019) <br />Lipase member H is a downstream molecular target of hypoxia inducible factor-1alpha and promotes papillary thyroid carcinoma cell migration in BCPAP and KTC-1 cell lines<br /><i>Cancer Manag Res</i> <b>11</b>: 931<br /><br />Li Y, Yin S, Hou J, Meng L, Gao M, Sun Y, Zhang C, Bai S, Ren J, Yu C (2019) <br />Metal coordination polymer induced perylene probe excimer fluorescence and its application in acetylcholinesterase sensing and alpha-fetoprotein immunoassay<br /><i>Analyst</i> <b>144</b>: 2034<br /><br />Ling L, Liu Y, Sun Y, Cai Y, Jiang Y, Chen L, He L, Xue J (2019) <br />Distribution characteristics of sweat gland nerve fibres in normal humans identified by acetylcholinesterase histochemical staining<br /><i>Clin Neurol Neurosurg</i> <b>189</b>: 105620<br /><br />Pu Z, Xu W, Lin Y, Shen J, Sun Y (2019) <br />Donepezil decreases heart rate in elderly patients with Alzheimer's disease<br /><i>Int J Clinical Pharmacology & Therapeutics</i> <b>57</b>: 94<br /><br />Sun Z, Chang B, Huang A, Hao S, Gao M, Sun Y, Shi M, Jin L, Zhang W, Zhao J, Teng G, Han L, Tian H, Liang Q, Zhang JY, Zou Z (2019) <br />Plasma levels of soluble ST2, but not IL-33, correlate with the severity of alcoholic liver disease<br /><i>J Cell Mol Med</i> <b>23</b>: 887<br /><br />Wei W, Wu X, Zhou J, Sun Y, Kong Y, Yang X (2019) <br />Noninvasive Evaluation of Liver Fibrosis Reverse Using Artificial Neural Network Model for Chronic Hepatitis B Patients<br /><i>Comput Math Methods Med</i> <b>2019</b>: 7239780<br /><br />Zou C, Li L, Miki D, Li D, Tang Q, Xiao L, Rajput S, Deng P, Peng L, Jia W, Huang R, Zhang M, Sun Y, Hu J, Fu X, Schnable PS, Chang Y, Li F, Zhang H, Feng B, Zhu X, Liu R, Schnable JC, Zhu JK (2019) <br />The genome of broomcorn millet<br /><i>Nat Commun</i> <b>10</b>: 436<br /><br />Cai J, Wang B, Li J, Chen Z, Rao M, Muyldermans S, Hua X, Xie X, Wang H, Yang J, Xu Z, Shen Y, Sun Y (2018) <br />Guided Evolution of Recombinant Bombyx mori Acetylcholinesterase II by Homology Modeling to Change Pesticide Sensitivity<br /><i>Int J Mol Sci</i> <b>19</b>: <br /><br />Chai L, Yang X, Liu M, Liu C, Han L, Guo H, Li C, Sun Y, Li X, Xiao M, Fang Z (2018) <br />Biopanning of allergens from wasp sting patients<br /><i>Bioscience Reports</i> <b>38</b>: <br /><br />Diao J, Yu X, Ma L, Li Y, Sun Y (2018) <br />Protein Surface Structural Recognition in Inactive Areas: A New Immobilization Strategy for Acetylcholinesterase<br /><i>Bioconjug Chem</i> <b>29</b>: 1703<br /><br />Guo R, Li H, Li X, Sun Y, Miao H, Ma D, Hong F, Zhang Y, Guan Y, Li J, Tian M, Wang Y (2018) <br />Increased Neuroligin 2 Levels in the Postsynaptic Membrane in Spinal Dorsal Horn may Contribute to Postoperative Pain<br /><i>Neuroscience</i> <b>382</b>: 14<br /><br />He Q, Liu J, Lan JS, Ding J, Sun Y, Fang Y, Jiang N, Yang Z, Sun L, Jin Y, Xie SS (2018) <br />Coumarin-dithiocarbamate hybrids as novel multitarget AChE and MAO-B inhibitors against Alzheimer's disease: Design, synthesis and biological evaluation<br /><i>Bioorg Chem</i> <b>81</b>: 512<br /><br />Lau SKP, Zhang L, Luk HKH, Xiong L, Peng X, Li KSM, He X, Zhao PS, Fan RYY, Wong ACP, Ahmed SS, Cai JP, Chan JFW, Sun Y, Jin D, Chen H, Lau TCK, Kok RKH, Li W, Yuen KY, Woo PCY (2018) <br />Receptor Usage of a Novel Bat Lineage C Betacoronavirus Reveals Evolution of Middle East Respiratory Syndrome-Related Coronavirus Spike Proteins for Human Dipeptidyl Peptidase 4 Binding<br /><i>J Infect Dis</i> <b>218</b>: 197<br /><br />Sun Y, Tan H, Li Y (2018) <br />A colorimetric assay for acetylcholinesterase activity and inhibitor screening based on the thiocholine-induced inhibition of the oxidative power of MnO2 nanosheets on 3,3',5,5'-tetramethylbenzidine<br /><i>Mikrochim Acta</i> <b>185</b>: 446<br /><br />Wang J, Tang X, Li Y, Zhang R, Zhu L, Chen J, Sun Y, Zhang Q, Wang W (2018) <br />Computational evidence for the degradation mechanism of haloalkane dehalogenase LinB and mutants of Leu248 to 1-chlorobutane<br /><i>Phys Chem Chem Phys</i> <b>20</b>: 20540<br /><br />Xing G, Li M, Sun Y, Rui M, Zhuang Y, Lv H, Han J, Jia Z, Xie W (2018) <br />Neurexin-Neuroligin 1 regulates synaptic morphology and function via the WAVE regulatory complex in Drosophila neuromuscular junction<br /><i>Elife</i> <b>7</b>: <br /><br />Yuan G, An L, Sun Y, Xu G, Du P (2018) <br />Improvement of Learning and Memory Induced by Cordyceps Polypeptide Treatment and the Underlying Mechanism<br /><i>Evid Based Complement Alternat Med</i> <b>2018</b>: 9419264<br /><br />Zhang T, Liu P, Sun Y, Ren N, Nie S (2018) <br />The Impairment of Trans Fatty Acids on Learning, Memory and Brain Amino Acid Neurotransmitters in Mice<br /><i>J Nutr Sci Vitaminol (Tokyo)</i> <b>64</b>: 63<br /><br />Chai L, Donkor PO, Wang K, Sun Y, Oppong MB, Ding L, Qiu F (2017) <br />Metabolic profiles of corydaline in rats by ultra-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry<br /><i>Xenobiotica</i> <br /><br />Dong XW, Jia YL, Ge LT, Jiang B, Jiang JX, Shen J, Jin YC, Guan Y, Sun Y, Xie QM (2017) <br />Soluble epoxide hydrolase inhibitor AUDA decreases bleomycin-induced pulmonary toxicity in mice by inhibiting the p38/Smad3 pathways<br /><i>Toxicology</i> <b>389</b>: 31<br /><br />Huang A, Chang B, Sun Y, Lin H, Li B, Teng G, Zou ZS (2017) <br />Disease spectrum of alcoholic liver disease in Beijing 302 Hospital from 2002 to 2013: A large tertiary referral hospital experience from 7422 patients<br /><i>Medicine (Baltimore)</i> <b>96</b>: e6163<br /><br />Ku LE, Li CY, Sun Y (2017) <br />Can Persistence With Cholinesterase Inhibitor Treatment Lower Mortality and Health-Care Costs Among Patients With Alzheimer's Disease? A Population-Based Study in Taiwan<br /><i>Am J Alzheimers Dis Other Demen</i> <br /><br />Liu Z, Cai W, Lang M, Yan R, Li Z, Zhang G, Yu P, Wang Y, Sun Y, Zhang Z (2017) <br />Neuroprotective Effects and Mechanisms of Action of Multifunctional Agents Targeting Free Radicals, Monoamine Oxidase B and Cholinesterase in Parkinson's Disease Model<br /><i>Journal of Molecular Neuroscience</i> <b>61</b>: 498<br /><br />Wang S, Zhang J, Jiao W, Li J, Xun X, Sun Y, Guo X, Huan P, Dong B, Zhang L, Hu X, Sun X, Wang J, Zhao C, Wang Y, Wang D, Huang X, Wang R, Lv J, Li Y, Zhang Z, Liu B, Lu W, Hui Y, Liang J, Zhou Z, Hou R, Li X, Liu Y, Li H, Ning X, Lin Y, Zhao L, Xing Q, Dou J, Mao J, Guo H, Dou H, Li T, Mu C, Jiang W, Fu Q, Fu X, Miao Y, Liu J, Yu Q, Li R, Liao H, Kong Y, Jiang Z, Chourrout D, Bao Z (2017) <br />Scallop genome provides insights into evolution of bilaterian karyotype and development<br /><i>Nat Ecol Evol</i> <b>1</b>: 120<br /><br />Wu Y, Sun Y, Xiao F, Wu Z, Yu R (2017) <br />Sensitive inkjet printing paper-based colormetric strips for acetylcholinesterase inhibitors with indoxyl acetate substrate<br /><i>Talanta</i> <b>162</b>: 174<br /><br />Zhang J, Song W, Sun Y, Shan A (2017) <br />Effects of phoxim-induced hepatotoxicity on SD rats and the protection of vitamin E<br /><i>Environ Sci Pollut Res Int</i> <b>24</b>: 24916<br /><br />Zhang X, Sun L, Yuan J, Sun Y, Gao Y, Zhang L, Li S, Dai H, Hamel JF, Liu C, Yu Y, Liu S, Lin W, Guo K, Jin S, Xu P, Storey KB, Huan P, Zhang T, Zhou Y, Zhang J, Lin C, Li X, Xing L, Huo D, Sun M, Wang L, Mercier A, Li F, Yang H, Xiang J (2017) <br />The sea cucumber genome provides insights into morphological evolution and visceral regeneration<br /><i>PLoS Biol</i> <b>15</b>: e2003790<br /><br />Ai R, Sun Y, Guo Z, Wei W, Zhou L, Liu F, Hendricks DT, Xu Y, Zhao X (2016) <br />NDRG1 overexpression promotes the progression of esophageal squamous cell carcinoma through modulating Wnt signaling pathway<br /><i>Cancer Biol Ther</i> <b>17</b>: 943<br /><br />Chen Y, Bian Y, Sun Y, Kang C, Yu S, Fu T, Li W, Pei Y, Sun H (2016) <br />Identification of 4-aminoquinoline core for the design of new cholinesterase inhibitors<br /><i>PeerJ</i> <b>4</b>: e2140<br /><br />Jin G, Bai D, Yin S, Yang Z, Zou D, Zhang Z, Li X, Sun Y, Zhu Q (2016) <br />Silibinin rescues learning and memory deficits by attenuating microglia activation and preventing neuroinflammatory reactions in SAMP8 mice<br /><i>Neuroscience Letters</i> <b>629</b>: 256<br /><br />Liu W, Lang M, Youdim MB, Amit T, Sun Y, Zhang Z, Wang Y, Weinreb O (2016) <br />Design, synthesis and evaluation of novel dual monoamine-cholinesterase inhibitors as potential treatment for Alzheimer's disease<br /><i>Neuropharmacology</i> <b>109</b>: 376<br /><br />Lv Y, Wang W, Hong S, Lei Z, Fang F, Guo Q, Hu S, Tian M, Liu B, Zhang D, Sun Y, Ma L, Shen B, Zhou D, Zhu C (2016) <br />Comparative transcriptome analyses of deltamethrin-susceptible and -resistant Culex pipiens pallens by RNA-seq<br /><i>Mol Genet Genomics</i> <b>291</b>: 309<br /><br />Sun Y, De Vos P, Heylen K (2016) <br />Nitrous oxide emission by the non-denitrifying, nitrate ammonifier Bacillus licheniformis<br /><i>BMC Genomics</i> <b>17</b>: 68<br /><br />Wang Y, Sun Y, Guo Y, Wang Z, Huang L, Li X (2016) <br />Dual functional cholinesterase and MAO inhibitors for the treatment of Alzheimer's disease: synthesis, pharmacological analysis and molecular modeling of homoisoflavonoid derivatives<br /><i>J Enzyme Inhib Med Chem</i> <b>31</b>: 389<br /><br />Wang P, He J, Sun Y, Reynolds M, Zhang L, Han S, Liang S, Sui H, Lin Y (2016) <br />Display of fungal hydrophobin on the Pichia pastoris cell surface and its influence on Candida antarctica lipase B<br /><i>Applied Microbiology & Biotechnology</i> <b>100</b>: 5883<br /><br />Yan X, Wang J, Sun Y, Zhu J, Wu S (2016) <br />Facilitating the Evolution of Esterase Activity from a Promiscuous Enzyme (Mhg) with Catalytic Functions of Amide Hydrolysis and Carboxylic Acid Perhydrolysis by Engineering the Substrate Entrance Tunnel<br /><i>Applied Environmental Microbiology</i> <b>82</b>: 6748<br /><br />Yang Y, Shao Y, Zhu M, Li Q, Yang F, Lu X, Xu C, Xiao B, Sun Y, Guo J (2016) <br />Using gastric juice lncRNA-ABHD11-AS1 as a novel type of biomarker in the screening of gastric cancer<br /><i>Tumour Biol</i> <b>37</b>: 1183<br /><br />Yao R, Ming Z, Yan L, Li S, Wang F, Ma S, Yu C, Yang M, Chen L, Li Y, Yan C, Miao D, Sun Z, Yan J, Sun Y, Wang L, Chu J, Fan S, He W, Deng H, Nan F, Li J, Rao Z, Lou Z, Xie D (2016) <br />DWARF14 is a non-canonical hormone receptor for strigolactone<br /><i>Nature</i> <b>536</b>: 469<br /><br />Zhang L, Zhou Z, Guo Q, Fokkens L, Miskei M, Pocsi I, Zhang W, Chen M, Wang L, Sun Y, Donzelli BG, Gibson DM, Nelson DR, Luo JG, Rep M, Liu H, Yang S, Wang J, Krasnoff SB, Xu Y, Molnar I, Lin M (2016) <br />Insights into Adaptations to a Near-Obligate Nematode Endoparasitic Lifestyle from the Finished Genome of Drechmeria coniospora<br /><i>Sci Rep</i> <b>6</b>: 23122<br /><br />He S, Chousterman BG, Fenn A, Anzai A, Nairz M, Brandt M, Hilgendorf I, Sun Y, Ye YX, Iwamoto Y, Tricot B, Weissleder R, Macphee C, Libby P, Nahrendorf M, Swirski FK (2015) <br />Lp-PLA2 Antagonizes Left Ventricular Healing After Myocardial Infarction by Impairing the Appearance of Reparative Macrophages<br /><i>Circ Heart Fail</i> <b>8</b>: 980<br /><br />Sun Y, Wang B, Shu S, Zhang H, Xu C, Wu L, Xia C (2015) <br />Critical thresholds of liver function parameters for ketosis prediction in dairy cows using receiver operating characteristic (ROC) analysis<br /><i>Vet Q</i> <b>35</b>: 159<br /><br />Xie L, Sun Y, Tong Y, Liu Y, Deng Y (2015) <br />Association of endothelial lipase gene-384A/C with coronary artery disease in Han Chinese people<br /><i>BMJ Open</i> <b>5</b>: e007621<br /><br />Yang K, Tian Z, Chen C, Luo L, Zhao B, Wang Z, Yu L, Li Y, Sun Y, Li W, Chen Y, Zhang Y, Ai D, Zhao J, Shang C, Ma Y, Wu B, Wang M, Gao L, Sun D, Zhang P, Guo F, Wang W, Wang J, Varshney RK, Ling HQ, Wan P (2015) <br />Genome sequencing of adzuki bean (Vigna angularis) provides insight into high starch and low fat accumulation and domestication<br /><i>Proc Natl Acad Sci U S A</i> <b>112</b>: 13213<br /><br />Gu Y, Yang C, Wang X, Geng W, Sun Y, Feng J, Wang Y, Quan Y, Che Y, Zhang C, Gong T, Zhang W, Gao W, Zuo Z, Song C, Wang S (2014) <br />Genome Sequence of the epsilon-Poly-l-Lysine-Producing Strain Streptomyces albulus NK660, Isolated from Soil in Gutian, Fujian Province, China<br /><i>Genome Announc</i> <b>2</b>: e00532<br /><br />Huang L, Miao H, Sun Y, Meng F, Li X (2014) <br />Discovery of indanone derivatives as multi-target-directed ligands against Alzheimer's disease<br /><i>Eur Journal of Medicinal Chemistry</i> <b>87C</b>: 429<br /><br />Mao F, Yan J, Li J, Jia X, Miao H, Sun Y, Huang L, Li X (2014) <br />New multi-target-directed small molecules against Alzheimer's disease: a combination of resveratrol and clioquinol<br /><i>Org Biomol Chem</i> <b>12</b>: 5936<br /><br />Mattheolabakis G, Wong CC, Sun Y, Amella CA, Richards R, Constantinides PP, Rigas B (2014) <br />Pegylation improves the pharmacokinetics and bioavailability of small-molecule drugs hydrolyzable by esterases: a study of phospho-Ibuprofen<br /><i>Journal of Pharmacology & Experimental Therapeutics</i> <b>351</b>: 61<br /><br />Su Y, Wang Q, Wang C, Chan K, Sun Y, Kuang H (2014) <br />The treatment of Alzheimer's disease using Chinese Medicinal Plants: From disease models to potential clinical applications<br /><i>J Ethnopharmacol</i> <b>152</b>: 403<br /><br />Sun Y, Peng Y, Li LG, Zheng LW, Lin DJ, Li LZ, Song SJ (2014) <br />A Platform for Screening Potential Anticholinesterase Fractions and Components Obtained from Anemarrhena asphodeloides Bge for Treating Alzheimer's Disease<br /><i>Evid Based Complement Alternat Med</i> <b>2014</b>: 524650<br /><br />Sun Y, Yin S, Feng Y, Li J, Zhou J, Liu C, Zhu G, Guo Z (2014) <br />Molecular Basis of the General Base Catalysis of an alpha/beta-Hydrolase Catalytic Triad<br /><i>Journal of Biological Chemistry</i> <b>289</b>: 15867<br /><br />Sun Y, Xu YH, Du H, Quinn B, Liou B, Stanton L, Inskeep V, Ran H, Jakubowitz P, Grilliot N, Grabowski GA (2014) <br />Reversal of advanced disease in lysosomal acid lipase deficient mice: a model for lysosomal acid lipase deficiency disease<br /><i>Mol Genet Metab</i> <b>112</b>: 229<br /><br />You X, Bian C, Zan Q, Xu X, Liu X, Chen J, Wang J, Qiu Y, Li W, Zhang X, Sun Y, Chen S, Hong W, Li Y, Cheng S, Fan G, Shi C, Liang J, Tom Tang Y, Yang C, Ruan Z, Bai J, Peng C, Mu Q, Lu J, Fan M, Yang S, Huang Z, Jiang X, Fang X, Zhang G, Zhang Y, Polgar G, Yu H, Li J, Liu Z, Ravi V, Coon SL, Yang H, Venkatesh B, Shi Q (2014) <br />Mudskipper genomes provide insights into the terrestrial adaptation of amphibious fishes<br /><i>Nat Commun</i> <b>5</b>: 5594<br /><br />Zhou D, Zhang D, Ding G, Shi L, Hou Q, Ye Y, Xu Y, Zhou H, Xiong C, Li S, Yu J, Hong S, Yu X, Zou P, Chen C, Chang X, Wang W, Lv Y, Sun Y, Ma L, Shen B, Zhu C (2014) <br />Genome sequence of Anopheles sinensis provides insight into genetics basis of mosquito competence for malaria parasites<br /><i>BMC Genomics</i> <b>15</b>: 42<br /><br />Hu ZY, Li XX, Du FF, Yang JL, Niu W, Xu F, Wang FQ, Li C, Sun Y (2013) <br />Pharmacokinetic evaluation of the anticancer prodrug simmitecan in different experimental animals<br /><i>Acta Pharmacol Sin</i> <b>34</b>: 1437<br /><br />Luo Z, Sheng J, Sun Y, Lu C, Yan J, Liu A, Luo HB, Huang L, Li X (2013) <br />Synthesis and Evaluation of Multi-Target-Directed Ligands against Alzheimer's Disease Based on the Fusion of Donepezil and Ebselen<br /><i>Journal of Medicinal Chemistry</i> <b>56</b>: 9089<br /><br />Seim I, Fang X, Xiong Z, Lobanov AV, Huang Z, Ma S, Feng Y, Turanov AA, Zhu Y, Lenz TL, Gerashchenko MV, Fan D, Hee Yim S, Yao X, Jordan D, Xiong Y, Ma Y, Lyapunov AN, Chen G, Kulakova OI, Sun Y, Lee SG, Bronson RT, Moskalev AA, Sunyaev SR, Zhang G, Krogh A, Wang J, Gladyshev VN (2013) <br />Genome analysis reveals insights into physiology and longevity of the Brandt's bat Myotis brandtii<br /><i>Nat Commun</i> <b>4</b>: 2212<br /><br />Sun Y, Chen J, Chen X, Huang L, Li X (2013) <br />Inhibition of cholinesterase and monoamine oxidase-B activity by Tacrine-Homoisoflavonoid hybrids<br /><i>Bioorganic & Medicinal Chemistry</i> <b>21</b>: 7406<br /><br />Sun Y, Yang Y, Wang C, Liu J, Shi W, Zhu X, Lu L, Li Q (2013) <br />Cell debris self-immobilized thermophilic lipase: a biocatalyst for synthesizing aliphatic polyesters<br /><i>Appl Biochem Biotechnol</i> <b>170</b>: 399<br /><br />Weng PH, Chen JH, Chen TF, Sun Y, Wen LL, Yip PK, Chu YM, Chen YC (2013) <br />CHRNA7 Polymorphisms and Response to Cholinesterase Inhibitors in Alzheimer's Disease<br /><i>PLoS ONE</i> <b>8</b>: e84059<br /><br />Xue L, Zhao Y, Yu L, Sun Y, Yan K, Li Y, Huang X, Qu Y (2013) <br />Choline acetate enhanced the catalytic performance of Candida rogusa lipase in AOT reverse micelles<br /><i>Colloids Surf B Biointerfaces</i> <b>105C</b>: 81<br /><br />Dong J, Li Z, Lei H, He Y, Wang H, Sun Y (2012) <br />[Expression and molecular evolution of recombinant acetylcholinesterase for detection of pesticide residues: a review]<br /><i>Sheng Wu Gong Cheng Xue Bao</i> <b>28</b>: 557<br /><br />Guo W, Liu S, Peng J, Wei X, Sun Y, Qiu Y, Gao G, Wang P, Xu Y (2012) <br />Examining the interactome of huperzine A by magnetic biopanning<br /><i>PLoS ONE</i> <b>7</b>: e37098<br /><br />He G, Sun Y, Li F (2012) <br />RNA interference of two acetylcholinesterase genes in Plutella xylostella reveals their different functions<br /><i>Archives of Insect Biochemistry & Physiology</i> <b>79</b>: 75<br /><br />Huang L, Su T, Shan W, Luo Z, Sun Y, He F, Li X (2012) <br />Inhibition of cholinesterase activity and amyloid aggregation by berberine-phenyl-benzoheterocyclic and tacrine-phenyl-benzoheterocyclic hybrids<br /><i>Bioorganic & Medicinal Chemistry</i> <b>20</b>: 3038<br /><br />Jirimutu, Wang Z, Ding G, Chen G, Sun Y, Sun Z, Zhang H, Wang L, Hasi S, Zhang Y, Li J, Shi Y, Xu Z, He C, Yu S, Li S, Zhang W, Batmunkh M, Ts B, Narenbatu, Unierhu, Bat-Ireedui S, Gao H, Baysgalan B, Li Q, Jia Z, Turigenbayila, Subudenggerile, Narenmanduhu, Wang J, Pan L, Chen Y, Ganerdene Y, Dabxilt, Erdemt, Altansha, Altansukh, Liu T, Cao M, Aruuntsever, Bayart, Hosblig, He F, Zha-ti A, Zheng G, Qiu F, Zhao L, Zhao W, Liu B, Li C, Tang X, Guo C, Liu W, Ming L, Temuulen, Cui A, Li Y, Gao J, Wurentaodi, Niu S, Sun T, Zhai Z, Zhang M, Chen C, Baldan T, Bayaer T, Meng H (2012) <br />Genome sequences of wild and domestic bactrian camels<br /><i>Nat Commun</i> <b>3</b>: 1202<br /><br />Wang X, Sun Y, Ke F, Zhao H, Liu T, Xu L, Liu Y, Yan Y (2012) <br />Constitutive expression of Yarrowia lipolytica lipase LIP2 in Pichia pastoris using GAP as promoter<br /><i>Appl Biochem Biotechnol</i> <b>166</b>: 1355<br /><br />Hu Z, Sun Y, Du F, Niu W, Xu F, Huang Y, Li C (2011) <br />Accurate determination of the anticancer prodrug simmitecan and its active metabolite chimmitecan in various plasma samples based on immediate deactivation of blood carboxylesterases<br /><i>Journal of Chromatography A</i> <b>1218</b>: 6646<br /><br />Zhu F, Wu F, Ma Y, Liu G, Li Z, Sun Y, Pei Z (2011) <br />Decrease in the production of beta-amyloid by berberine inhibition of the expression of beta-secretase in HEK293 cells<br /><i>BMC Neurosci</i> <b>12</b>: 125<br /><br />Cheng S, Li L, He S, Liu J, Sun Y, He M, Grasing K, Premont RT, Suo WZ (2010) <br />GRK5 deficiency accelerates {beta}-amyloid accumulation in Tg2576 mice via impaired cholinergic activity<br /><i>Journal of Biological Chemistry</i> <b>285</b>: 41541<br /><br />Lou Z, Li M, Sun Y, Liu Y, Liu Z, Wu W, Rao Z (2010) <br />Crystal structure of a secreted lipase from Gibberella zeae reveals a novel double-lock mechanism<br /><i>Protein Cell</i> <b>1</b>: 760<br /><br />Doody RS, Ferris SH, Salloway S, Sun Y, Goldman R, Watkins WE, Xu Y, Murthy AK (2009) <br />Donepezil treatment of patients with MCI: a 48-week randomized, placebo-controlled trial<br /><i>Neurology</i> <b>72</b>: 1555<br /><br />Duan Y, Zhou L, Hall DG, Li W, Doddapaneni H, Lin H, Liu L, Vahling CM, Gabriel DW, Williams KP, Dickerman A, Sun Y, Gottwald T (2009) <br />Complete genome sequence of citrus huanglongbing bacterium, 'Candidatus Liberibacter asiaticus' obtained through metagenomics<br /><i>Mol Plant Microbe Interact</i> <b>22</b>: 1011<br /><br />Wang J, Li Q, Sun Y, Zheng H, Cui Y, Li H, Zhou H, Hao X (2009) <br />Clinicopathologic features between multicentric occurence and intrahepatic metastasis of multiple hepatocellular carcinomas related to HBV<br /><i>Surg Oncol</i> <b>18</b>: 25<br /><br />Xu Y, Liu H, Du W, Sun Y, Ou X, Liu D (2009) <br />Integrated production for biodiesel and 1,3-propanediol with lipase-catalyzed transesterification and fermentation<br /><i>Biotechnol Lett</i> <b>31</b>: 1335<br /><br />Ren MY, Bai S, Zhang DH, Sun Y (2008) <br />pH memory of immobilized lipase for (+/-)-menthol resolution in ionic liquid<br /><i>Journal of Agricultural and Food Chemistry</i> <b>56</b>: 2388<br /><br />Sun Y, Lai MS, Lu CJ, Chen RC (2008) <br />How long can patients with mild or moderate Alzheimer's dementia maintain both the cognition and the therapy of cholinesterase inhibitors: a national population-based study<br /><i>Eur Journal of Neurology</i> <b>15</b>: 278<br /><br />Sun Y, Li M, Zhang Y, Liu L, Liu Y, Liu Z, Li X, Lou Z (2008) <br />Crystallization and preliminary crystallographic analysis of Gibberella zeae extracellular lipase<br /><i>Acta Crystallographica Sect F Struct Biol Cryst Commun</i> <b>64</b>: 813<br /><br />Deangelis YM, Saunders CW, Johnstone KR, Reeder NL, Coleman CG, Kaczvinsky JR, Jr., Gale C, Walter R, Mekel M, Lacey MP, Keough TW, Fieno A, Grant RA, Begley B, Sun Y, Fuentes G, Youngquist RS, Xu J, Dawson TL, Jr. (2007) <br />Isolation and expression of a Malassezia globosa lipase gene, LIP1<br /><i>Journal of Investigative Dermatology</i> <b>127</b>: 2138<br /><br />Sun Y, Lu CJ, Chien KL, Chen ST, Chen RC (2007) <br />Efficacy of multivitamin supplementation containing vitamins B6 and B12 and folic acid as adjunctive treatment with a cholinesterase inhibitor in Alzheimer's disease: a 26-week, randomized, double-blind, placebo-controlled study in Taiwanese patients<br /><i>Clin Ther</i> <b>29</b>: 2204<br /><br />Wu J, Hong Q, Sun Y, Hong Y, Yan Q, Li S (2007) <br />Analysis of the role of LinA and LinB in biodegradation of delta-hexachlorocyclohexane<br /><i>Environ Microbiol</i> <b>9</b>: 2331<br /><br />Xu J, Saunders CW, Hu P, Grant RA, Boekhout T, Kuramae EE, Kronstad JW, Deangelis YM, Reeder NL, Johnstone KR, Leland M, Fieno AM, Begley WM, Sun Y, Lacey MP, Chaudhary T, Keough T, Chu L, Sears R, Yuan B, Dawson TL, Jr. (2007) <br />Dandruff-associated Malassezia genomes reveal convergent and divergent virulence traits shared with plant and human fungal pathogens<br /><i>Proc Natl Acad Sci U S A</i> <b>104</b>: 18730<br /><br />Zhang DH, Guo Z, Dong XY, Sun Y (2007) <br />Characterization of lipase in reversed micelles formulated with cibacron blue F-3GA modified span 85<br /><i>Biotechnol Prog</i> <b>23</b>: 108<br /><br />Yu J, Wang J, Lin W, Li S, Li H, Zhou J, Ni P, Dong W, Hu S, Zeng C, Zhang J, Zhang Y, Li R, Xu Z, Li X, Zheng H, Cong L, Lin L, Yin J, Geng J, Li G, Shi J, Liu J, Lv H, Li J, Deng Y, Ran L, Shi X, Wang X, Wu Q, Li C, Ren X, Li D, Liu D, Zhang X, Ji Z, Zhao W, Sun Y, Zhang Z, Bao J, Han Y, Dong L, Ji J, Chen P, Wu S, Xiao Y, Bu D, Tan J, Yang L, Ye C, Xu J, Zhou Y, Yu Y, Zhang B, Zhuang S, Wei H, Liu B, Lei M, Yu H, Li Y, Xu H, Wei S, He X, Fang L, Huang X, Su Z, Tong W, Tong Z, Ye J, Wang L, Lei T, Chen C, Chen H, Huang H, Zhang F, Li N, Zhao C, Huang Y, Li L, Xi Y, Qi Q, Li W, Hu W, Tian X, Jiao Y, Liang X, Jin J, Gao L, Zheng W, Hao B, Liu S, Wang W, Yuan L, Cao M, McDermott J, Samudrala R, Wong GK, Yang H (2005) <br />The Genomes of Oryza sativa: a history of duplications<br /><i>PLoS Biol</i> <b>3</b>: e38<br /><br />Zhang LJ, Min SG, Li GX, Xiong YM, Sun Y (2005) <br />[The mechanism of carbofuran interacts with calf thymus DNA]<br /><i>Guang Pu Xue Yu Guang Pu Fen Xi</i> <b>25</b>: 739<br /><br />Zhou Z, Dai X, Gu X, Sun Y, Zheng G, Zheng J (2005) <br />Memantine alleviates toxicity induced by dichlorvos in rats<br /><i>J Occup Health</i> <b>47</b>: 96<br /><br />Guo Z, Sun Y (2004) <br />Characteristics of immobilized lipase on hydrophobic superparamagnetic microspheres to catalyze esterification<br /><i>Biotechnol Prog</i> <b>20</b>: 500<br /><br />Sun Y, Zhou X, Dong H, Tu G, Wang M, Wang B, Deng Z (2003) <br />A complete gene cluster from Streptomyces nanchangensis NS3226 encoding biosynthesis of the polyether ionophore nanchangmycin<br /><i>Chemical Biology</i> <b>10</b>: 431<br /><br />Feng Q, Zhang Y, Hao P, Wang S, Fu G, Huang Y, Li Y, Zhu J, Liu Y, Hu X, Jia P, Zhao Q, Ying K, Yu S, Tang Y, Weng Q, Zhang L, Lu Y, Mu J, Zhang LS, Yu Z, Fan D, Liu X, Lu T, Li C, Wu Y, Sun T, Lei H, Li T, Hu H, Guan J, Wu M, Zhang R, Zhou B, Chen Z, Chen L, Jin Z, Wang R, Yin H, Cai Z, Ren S, Lv G, Gu W, Zhu G, Tu Y, Jia J, Chen J, Kang H, Chen X, Shao C, Sun Y, Hu Q, Zhang X, Zhang W, Wang L, Ding C, Sheng H, Gu J, Chen S, Ni L, Zhu F, Chen W, Lan L, Lai Y, Cheng Z, Gu M, Jiang J, Li J, Hong G, Xue Y, Han B (2002) <br />Sequence and analysis of rice chromosome 4<br /><i>Nature</i> <b>420</b>: 316<br /><br />Hou Y, Fu F, Liu S, Liu C, Sun Y, Qiu S (2002) <br />[The profiles of free organophosphorus poisons in the bile of rabbits poisoned with different organophosphates]<br /><i>Zhonghua Nei Ke Za Zhi</i> <b>41</b>: 795<br /><br />Sun Y, Zhou Z, Hu Y, Chen J, Jin T (2002) <br />[The acute effects of dimethoate on the muscarinic-receptors of rat brains and the relationship between muscarinic-receptors and cholinesterase]<br /><i>Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi</i> <b>20</b>: 293<br /><br />