Terajima T, Inoue H, Shimomura K, Iwasaki F, Sasaki A, Ito Y, Kamijima M, Tomizawa M (2023) <br />Organophosphate agent action at the fatty acid amide hydrolase enhancing anandamide-induced apoptosis in NG108-15 cells<br /><i>Journal of Toxicological Sciences</i> <b>48</b>: 421<br /><br />Suzuki H, Ito Y, Noro Y, Koketsu M, Kamijima M, Tomizawa M (2014) <br />Organophosphate agents induce plasma hypertriglyceridemia in mouse via single or dual inhibition of the endocannabinoid hydrolyzing enzyme(s)<br /><i>Toxicol Lett</i> <b>225</b>: 153<br /><br />Tomizawa M, Casida JE (2011) <br />Neonicotinoid insecticides: highlights of a symposium on strategic molecular designs<br /><i>Journal of Agricultural and Food Chemistry</i> <b>59</b>: 2883<br /><br />Tomizawa M, Casida JE (2011) <br />Unique neonicotinoid binding conformations conferring selective receptor interactions<br /><i>Journal of Agricultural and Food Chemistry</i> <b>59</b>: 2825<br /><br />Tomizawa M, Kagabu S, Casida JE (2011) <br />Receptor structure-guided neonicotinoid design<br /><i>Journal of Agricultural and Food Chemistry</i> <b>59</b>: 2918<br /><br />Ohno I, Tomizawa M, Durkin KA, Casida JE, Kagabu S (2009) <br />Bis-neonicotinoid insecticides: Observed and predicted binding interactions with the nicotinic receptor<br /><i>Bioorganic & Medicinal Chemistry Lett</i> <b>19</b>: 3449<br /><br />Ohno I, Tomizawa M, Durkin KA, Casida JE, Kagabu S (2009) <br />Neonicotinoid substituents forming a water bridge at the nicotinic acetylcholine receptor<br /><i>Journal of Agricultural and Food Chemistry</i> <b>57</b>: 2436<br /><br />Ohno I, Tomizawa M, Durkin KA, Naruse Y, Casida JE, Kagabu S (2009) <br />Molecular features of neonicotinoid pharmacophore variants interacting with the insect nicotinic receptor<br /><i>Chemical Research in Toxicology</i> <b>22</b>: 476<br /><br />Tomizawa M, Casida JE (2009) <br />Molecular recognition of neonicotinoid insecticides: the determinants of life or death<br /><i>Acc Chem Res</i> <b>42</b>: 260<br /><br />Tomizawa M, Talley TT, Park JF, Maltby D, Medzihradszky KF, Durkin KA, Cornejo-Bravo JM, Burlingame AL, Casida JE, Taylor P (2009) <br />Nicotinic agonist binding site mapped by methionine- and tyrosine-scanning coupled with azidochloropyridinyl photoaffinity labeling<br /><i>Journal of Medicinal Chemistry</i> <b>52</b>: 3735<br /><br />Talley TT, Harel M, Hibbs RE, Radic Z, Tomizawa M, Casida JE, Taylor P (2008) <br />Atomic interactions of neonicotinoid agonists with AChBP: molecular recognition of the distinctive electronegative pharmacophore<br /><i>Proc Natl Acad Sci U S A</i> <b>105</b>: 7606<br /><br />Tomizawa M, Kagabu S, Ohno I, Durkin KA, Casida JE (2008) <br />Potency and selectivity of trifluoroacetylimino and pyrazinoylimino nicotinic insecticides and their fit at a unique binding site niche<br /><i>Journal of Medicinal Chemistry</i> <b>51</b>: 4213<br /><br />Honda H, Tomizawa M, Casida JE (2007) <br />Insect muscarinic acetylcholine receptor: pharmacological and toxicological profiles of antagonists and agonists<br /><i>Journal of Agricultural and Food Chemistry</i> <b>55</b>: 2276<br /><br />Tomizawa M, Maltby D, Medzihradszky KF, Zhang N, Durkin KA, Presley J, Talley TT, Taylor P, Burlingame AL, Casida JE (2007) <br />Defining nicotinic agonist binding surfaces through photoaffinity labeling<br /><i>Biochemistry</i> <b>46</b>: 8798<br /><br />Tomizawa M, Talley TT, Maltby D, Durkin KA, Medzihradszky KF, Burlingame AL, Taylor P, Casida JE (2007) <br />Mapping the elusive neonicotinoid binding site<br /><i>Proc Natl Acad Sci U S A</i> <b>104</b>: 9075<br /><br />Honda H, Tomizawa M, Casida JE (2006) <br />Insect nicotinic acetylcholine receptors: neonicotinoid binding site specificity is usually but not always conserved with varied substituents and species<br /><i>Journal of Agricultural and Food Chemistry</i> <b>54</b>: 3365<br /><br />Honda H, Tomizawa M, Casida JE (2006) <br />Neo-nicotinoid metabolic activation and inactivation established with coupled nicotinic receptor-CYP3A4 and -aldehyde oxidase systems<br /><i>Toxicol Lett</i> <b>161</b>: 108<br /><br />Kanne DB, Dick RA, Tomizawa M, Casida JE (2005) <br />Neonicotinoid nitroguanidine insecticide metabolites: synthesis and nicotinic receptor potency of guanidines, aminoguanidines, and their derivatives<br /><i>Chemical Research in Toxicology</i> <b>18</b>: 1479<br /><br />Kanne DB, Tomizawa M, Durkin KA, Casida JE (2005) <br />6'-Methylpyrido[3,4-b]norhomotropane: synthesis and outstanding potency in relation to the alpha4beta2 nicotinic receptor pharmacophore model<br /><i>Bioorganic & Medicinal Chemistry Lett</i> <b>15</b>: 877<br /><br />Tomizawa M, Millar NS, Casida JE (2005) <br />Pharmacological profiles of recombinant and native insect nicotinic acetylcholine receptors<br /><i>Insect Biochemistry & Molecular Biology</i> <b>35</b>: 1347<br /><br />Tomizawa M, Casida JE (2005) <br />Neonicotinoid insecticide toxicology: mechanisms of selective action<br /><i>Annual Review of Pharmacology & Toxicology</i> <b>45</b>: 247<br /><br />Tomizawa M (2004) <br />Neonicotinoids and Derivatives: Effects in Mammalian Cells and Mice<br /><i>Journal of Pesticide Science</i> <b>29</b>: 177<br /><br />Zhang N, Tomizawa M, Casida JE (2004) <br />Alpha-nitro ketone as an electrophile and nucleophile: synthesis of 3-substituted 2-nitromethylenetetrahydrothiophene and -tetrahydrofuran as drosophila nicotinic receptor probes<br /><i>J Org Chem</i> <b>69</b>: 876<br /><br />Zhang N, Tomizawa M, Casida JE (2004) <br />Drosophila nicotinic receptors: evidence for imidacloprid insecticide and alpha-bungarotoxin binding to distinct sites<br /><i>Neuroscience Letters</i> <b>371</b>: 56<br /><br />Lee SJ, Tomizawa M, Casida JE (2003) <br />Nereistoxin and cartap neurotoxicity attributable to direct block of the insect nicotinic receptor/channel<br /><i>Journal of Agricultural and Food Chemistry</i> <b>51</b>: 2646<br /><br />Tomizawa M, Casida JE (2003) <br />Selective toxicity of neonicotinoids attributable to specificity of insect and mammalian nicotinic receptors<br /><i>Annual Review of Entomology</i> <b>48</b>: 339<br /><br />Tomizawa M, Zhang N, Durkin KA, Olmstead MM, Casida JE (2003) <br />The neonicotinoid electronegative pharmacophore plays the crucial role in the high affinity and selectivity for the Drosophila nicotinic receptor: an anomaly for the nicotinoid cation--pi interaction model<br /><i>Biochemistry</i> <b>42</b>: 7819<br /><br />Zhang N, Tomizawa M, Casida JE (2002) <br />Structural features of azidopyridinyl neonicotinoid probes conferring high affinity and selectivity for mammalian alpha4beta2 and Drosophila nicotinic receptors<br /><i>Journal of Medicinal Chemistry</i> <b>45</b>: 2832<br /><br />Tomizawa M, Casida JE (2001) <br />Structure and diversity of insect nicotinic acetylcholine receptors<br /><i>Pest Manag Sci</i> <b>57</b>: 914<br /><br />Tomizawa M, Cowan A, Casida JE (2001) <br />Analgesic and toxic effects of neonicotinoid insecticides in mice<br /><i>Toxicol Appl Pharmacol</i> <b>177</b>: 77<br /><br />Tomizawa M, Wen Z, Chin HL, Morimoto H, Kayser H, Casida JE (2001) <br />Photoaffinity labeling of insect nicotinic acetylcholine receptors with a novel [(3)H]azidoneonicotinoid<br /><i>Journal of Neurochemistry</i> <b>78</b>: 1359<br /><br />Tomizawa M, Casida JE (2000) <br />Imidacloprid, thiacloprid, and their imine derivatives up-regulate the alpha 4 beta 2 nicotinic acetylcholine receptor in M10 cells<br /><i>Toxicol Appl Pharmacol</i> <b>169</b>: 114<br /><br />Tomizawa M, Lee DL, Casida JE (2000) <br />Neonicotinoid insecticides: molecular features conferring selectivity for insect versus mammalian nicotinic receptors<br /><i>Journal of Agricultural and Food Chemistry</i> <b>48</b>: 6016<br /><br />Tomizawa M, Casida JE (1999) <br />Minor structural changes in nicotinoid insecticides confer differential subtype selectivity for mammalian nicotinic acetylcholine receptors<br /><i>British Journal of Pharmacology</i> <b>127</b>: 115<br /><br />Tomizawa M, Latli B, Casida JE (1996) <br />Novel neonicotinoid-agarose affinity column for Drosophila and Musca nicotinic acetylcholine receptors<br /><i>Journal of Neurochemistry</i> <b>67</b>: 1669<br /><br />Yoshida M, Tomizawa M, Wu SY, Quistad GB, Casida JE (1995) <br />Neuropathy target esterase of hen brain: active site reactions with 2-[octyl-3H]octyl-4H-1,3,2-benzodioxaphosphorin 2-oxide and 2-octyl-4H-1,3,2-[aryl-3H]benzodioxaphosphorin 2-oxide<br /><i>Journal of Neurochemistry</i> <b>64</b>: 1680<br /><br />