Estevez J, Terol M, Sogorb M, Vilanova E (2021)
Interactions of human acetylcholinesterase with phenyl valerate and acetylthiocholine: Thiocholine as an enhancer of phenyl valerate esterase activity
Chemico-Biological Interactions
Monroy-Noyola A, Almenares-Lopez D, Vilanova E (2021)
Hydrolysis of chiral organophosphorus compounds by phosphotriesterases and mammalian paraoxonase-1
Front Biosci (Landmark Ed) 26: 744
Monroy-Noyola A, Sogorb MA, Almenares-Lopez D, Vilanova E (2021)
DAEH N-terminal sequence of avian serum albumins as catalytic center of Cu (II)-dependent organophosphorus hydrolyzing A-esterase activity
Chemico-Biological Interactions
Fuster E, Candela H, Estevez J, Arias AJ, Vilanova E, Sogorb MA (2020)
Effects of silver nanoparticles on T98G human glioblastoma cells
Toxicol Appl Pharmacol 404: 115178
Estevez J, Rodrigues de Souza F, Romo M, Mangas I, Franca TCC, Vilanova E (2019)
Interactions of human butyrylcholinesterase with phenylvalerate and acetylthiocholine as substrates and inhibitors: kinetic and molecular modeling approaches
Archives of Toxicology 93: 1281
Monroy-Noyola A, Vilanova E, Campos F, Mederos P, Rendon N, Garcia-Hernandez J, Castillo-Guerrero JA, Rios C (2019)
O-hexyl O-2,5-dichlorophenyl phosphoramidate as a substrate for domestic and sea bird serum A-esterases: Hydrolysis levels, Cu(2+)- and Zn(2+)-dependence and stereoselectivity
Chemico-Biological Interactions 310: 108727
Estevez J, Benabent M, Selva V, Mangas I, Sogorb MA, Del Rio E, Vilanova E (2018)
Cholinesterase and phenyl valerate-esterase activities sensitive to organophosphorus compounds in membranes of chicken brain
Toxicology 410: 73
Monroy-Noyola A, Sogorb MA, Vilanova E (2018)
Albumin, the responsible protein of the Cu(2+)-dependent hydrolysis of O-hexyl O-2,5-dichlorophenyl phosphoramidate (HDCP) by chicken serum antagonistic stereoselectivity
Food & Chemical Toxicology 120: 523
Mangas I, Estevez J, Vilanova E, Franca TCC (2017)
New insights on molecular interactions of organophosphorus pesticides with esterases
Toxicology 376: 30
Mangas I, Radic Z, Taylor P, Ghassemian M, Candela H, Vilanova E, Estevez J (2017)
Butyrylcholinesterase identification in a phenylvalerate esterase-enriched fraction sensitive to low mipafox concentrations in chicken brain
Archives of Toxicology 91: 909
Mangas I, Vilanova E, Estevez J (2017)
Phenyl valerate esterase activity of human butyrylcholinesterase
Archives of Toxicology 91: 3295
Estevez J, Selva V, Benabent M, Mangas I, Sogorb MA, Vilanova E (2016)
Acetylcholine-hydrolyzing activities in soluble brain fraction: Characterization with reversible and irreversible inhibitors
Chemico-Biological Interactions 259: 374
Mangas I, Taylor P, Vilanova E, Estevez J, Franca TCC, Komives E, Radic Z (2016)
Resolving pathways of interaction of mipafox and a sarin analog with human acetylcholinesterase by kinetics, mass spectrometry and molecular modeling approaches
Archives of Toxicology 90: 603
Mangas I, Estevez J, Vilanova E (2016)
Esterases hydrolyze phenyl valerate activity as targets of organophosphorus compounds
Chemico-Biological Interactions 259: 358
Sogorb MA, Fuster E, Del Rio E, Estevez J, Vilanova E (2016)
Effects of mipafox, paraoxon, chlorpyrifos and its metabolite chlorpyrifos-oxon on the expression of biomarker genes of differentiation in D3 mouse embryonic stem cells
Chemico-Biological Interactions 259: 368
Sogorb MA, Pamies D, Estevan C, Estevez J, Vilanova E (2016)
Roles of NTE protein and encoding gene in development and neurodevelopmental toxicity
Chemico-Biological Interactions 259: 352
Vilanova E, Sogorb MA, Estevez J (2016)
Editorial
Chemico-Biological Interactions 259: 49
Monroy-Noyola A, Trujillo B, Yescas P, Martinez-Salazar F, Garcia-Jimenez S, Rios C, Vilanova E (2015)
Stereospecific hydrolysis of a phosphoramidate used as an OPIDP model by human sera with PON1 192 alloforms
Archives of Toxicology 89: 1801
Benabent M, Vilanova E, Mangas I, Sogorb MA, Estevez J (2014)
Interaction between substrates suggests a relationship between organophosphorus-sensitive phenylvalerate- and acetylcholine-hydrolyzing activities in chicken brain
Toxicol Lett 230: 132
Benabent M, Vilanova E, Sogorb MA, Estevez J (2014)
Cholinesterase assay by an efficient fixed time endpoint method
MethodsX 1: 258
Mangas I, Vilanova E, Benabent M, Estevez J (2014)
Separating esterase targets of organophosphorus compounds in the brain by preparative chromatography
Toxicol Lett 225: 167
Pamies D, Sogorb MA, Fabbri M, Gribaldo L, Collotta A, Scelfo B, Vilanova E, Harris G, Bal-Price A (2014)
Genomic and Phenotypic Alterations of the Neuronal-Like Cells Derived from Human Embryonal Carcinoma Stem Cells (NT2) Caused by Exposure to Organophosphorus Compounds Paraoxon and Mipafox
Int J Mol Sci 15: 905
Pamies D, Vilanova E, Sogorb MA (2014)
Functional pathways altered after silencing Pnpla6 (the codifying gene of neuropathy target esterase) in mouse embryonic stem cells under differentiation
In Vitro Cell Developmental Biology Anim 50: 261
Estevez J, Mangas I, Sogorb MA, Vilanova E (2013)
Interactions of neuropathy inducers and potentiators/promoters with soluble esterases
Chemico-Biological Interactions 203: 245
Estevan C, Vilanova E, Sogorb MA (2012)
Chlorpyrifos and its metabolites alter gene expression at non-cytotoxic concentrations in D3 mouse embryonic stem cells under in vitro differentiation: Considerations for embryotoxic risk assessment
Toxicol Lett 217: 14
Estevan C, Ferri F, Sogorb MA, Vilanova E (2012)
Characterization and evolution of exposure to volatile organic compounds in the Spanish shoemaking industry over a 5-year period
J Occup Environ Hyg 9: 653
Estevez J, Barril J, Vilanova E (2012)
Kinetics of inhibition of soluble peripheral nerve esterases by PMSF: a non-stable compound that potentiates the organophosphorus-induced delayed neurotoxicity
Archives of Toxicology 86: 767
Mangas I, Vilanova E, Estevez J (2012)
NTE and non-NTE esterases in brain membrane: kinetic characterization with organophosphates
Toxicology 297: 17
Mangas I, Vilanova E, Estevez J (2012)
Phenylmethylsulfonyl fluoride, a potentiator of neuropathy, alters the interaction of organophosphorus compounds with soluble brain esterases
Chemical Research in Toxicology 25: 2393
Mayer-Pinto M, Ignacio BL, Szechy MT, Viana MS, Curbelo-Fernandez MP, Lavrado HP, Junqueira AO, Vilanova E, Silva SH (2012)
How much is too little to detect impacts? A case study of a nuclear power plant
PLoS ONE 7: e47871
Estevez J, Garcia-Perez A, Barril J, Vilanova E (2011)
Inhibition with spontaneous reactivation of carboxyl esterases by organophosphorus compounds: paraoxon as a model
Chemical Research in Toxicology 24: 135
Mangas I, Vilanova E, Estevez J (2011)
Kinetics of the inhibitory interaction of organophosphorus neuropathy inducers and non-inducers in soluble esterases in the avian nervous system
Toxicol Appl Pharmacol 256: 360
Romero AC, Vilanova E, Sogorb MA (2011)
Shortening and Improving the Embryonic Stem Cell Test through the Use of Gene Biomarkers of Differentiation
J Toxicol 2011: 286034
Estevez J, Barril J, Vilanova E (2010)
Inhibition with spontaneous reactivation and the ongoing inhibition effect of esterases by biotinylated organophosphorus compounds: S9B as a model
Chemico-Biological Interactions 187: 397
Pamies D, Reig JA, Vilanova E, Sogorb MA (2010)
Expression of Neuropathy Target Esterase in mouse embryonic stem cells during differentiation
Archives of Toxicology 84: 481
Sogorb MA, Vilanova E (2010)
Serum albumins and detoxication of anti-cholinesterase agents
Chemico-Biological Interactions 187: 325
Sogorb MA, Gonzalez-Gonzalez I, Pamies D, Vilanova E (2010)
An alternative in vitro method for detecting neuropathic compounds based on acetylcholinesterase inhibition and on inhibition and aging of neuropathy target esterase (NTE)
Toxicol In Vitro 24: 942
Vilanova E, Coutinho C, Maia G, Mourao PA (2010)
Sulfated polysaccharides from marine sponges: conspicuous distribution among different cell types and involvement on formation of in vitro cell aggregates
Cell Tissue Research 340: 523
Estevez J, Vilanova E (2009)
Model equations for the kinetics of covalent irreversible enzyme inhibition and spontaneous reactivation: esterases and organophosphorus compounds
Crit Rev Toxicol 39: 427
Vilanova E, Coutinho CC, Mourao PA (2009)
Sulfated polysaccharides from marine sponges (Porifera): an ancestor cell-cell adhesion event based on the carbohydrate-carbohydrate interaction
Glycobiology 19: 860
Sogorb MA, Garcia-Arguelles S, Carrera V, Vilanova E (2008)
Serum albumin is as efficient as paraxonase in the detoxication of paraoxon at toxicologically relevant concentrations
Chemical Research in Toxicology 21: 1524
Carrera V, Sabater E, Vilanova E, Sogorb MA (2007)
A simple and rapid HPLC-MS method for the simultaneous determination of epinephrine, norepinephrine, dopamine and 5-hydroxytryptamine: application to the secretion of bovine chromaffin cell cultures
Journal of Chromatography B Analyt Technol Biomed Life Sciences 847: 88
Monroy-Noyola A, Rojas P, Vilanova E, Sogorb MA (2007)
Comparative hydrolysis of O-hexyl O-2,5-dichlorophenyl phosphoramidate and paraoxon in different tissues of vertebrates
Archives of Toxicology 81: 689
Monroy-Noyola A, Sogorb MA, Vilanova E (2007)
Stereospecific hydrolysis of a phosphoramidate as a model to understand the role of biotransformation in the neurotoxicity of chiral organophosphorus compounds
Toxicol Lett 170: 157
Quesada E, Castell JV, Vilanova E, Carrera V (2007)
Over-expression of neuropathy target esterase activity in bovine chromaffin cell cultures by adenovirus-mediated gene transfer
Toxicol Lett 168: 286
Quesada E, Sabater E, Sogorb MA, Vilanova E, Carrera V (2007)
Recovery of neuropathy target esterase activity after inhibition with mipafox and O-hexyl O-2,5-dichlorophenyl phosphoramidate in bovine chromaffin cell cultures
Chemico-Biological Interactions 165: 99
Sogorb MA, Alvarez-Escalante C, Carrera V, Vilanova E (2007)
An in vitro approach for demonstrating the critical role of serum albumin in the detoxication of the carbamate carbaryl at in vivo toxicologically relevant concentrations
Archives of Toxicology 81: 113
Sogorb MA, Ganga R, Vilanova E, Soler F (2007)
Plasma phenylacetate and 1-naphthyl acetate hydrolyzing activities of wild birds as possible non-invasive biomarkers of exposure to organophosphorus and carbamate insecticides
Toxicol Lett 168: 278
Romero D, Quesada E, Sogorb MA, Garcia-Fernandez AJ, Vilanova E, Carrera V (2006)
Comparison of chromaffin cells from several animal sources for their use as an in vitro model to study the mechanism of organophosphorous toxicity
Toxicol Lett 165: 221
Esteban J, de la Cruz Pellin M, Gimeno C, Barril J, Mora E, Gimenez J, Vilanova E (2004)
Detection of clinical interactions between methadone and anti-retroviral compounds using an enantioselective capillary electrophoresis for methadone analysis
Toxicol Lett 151: 243
Estevez J, Garcia-Perez AG, Barril J, Pellin M, Vilanova E (2004)
The inhibition of the high sensitive peripheral nerve soluble esterases by mipafox. A new mathematical processing for the kinetics of inhibition of esterases by organophosphorus compounds
Toxicol Lett 151: 171
Quesada E, Sogorb MA, Vilanova E, Carrera V (2004)
Bovine chromaffin cell cultures as model to study organophosporus neurotoxicity
Toxicol Lett 151: 163
Sogorb MA, Carrera V, Vilanova E (2004)
Hydrolysis of carbaryl by human serum albumin
Archives of Toxicology 78: 629
Sogorb MA, Vilanova E, Carrera V (2004)
Future applications of phosphotriesterases in the prophylaxis and treatment of organophosporus insecticide and nerve agent poisonings
Toxicol Lett 151: 219
Carrera V, Llopis I, Sastre J, Sogorb MA, Vilanova E (2003)
Distribution of serum paraoxon hydrolyzing activity in a large Spanish population using a routine automized method in clinical laboratory
J Anal Toxicol 27: 290
Garcia-Perez AG, Barril J, Estevez J, Vilanova E (2003)
Properties of phenyl valerate esterase activities from chicken serum are comparable with soluble esterases of peripheral nerves in relation with organophosphorus compounds inhibition
Toxicol Lett 142: 1
Sogorb MA, Carrera V, Benabent M, Vilanova E (2002)
Rabbit serum albumin hydrolyzes the carbamate carbaryl
Chemical Research in Toxicology 15: 520
Sogorb MA, Vilanova E (2002)
Enzymes involved in the detoxification of organophosphorus, carbamate and pyrethroid insecticides through hydrolysis
Toxicol Lett 128: 215
Barril J, Estevez J, Escudero MA, Cespedes MV, Niguez N, Sogorb MA, Monroy A, Vilanova E (1999)
Peripheral nerve soluble esterases are spontaneously reactivated after inhibition by paraoxon: implications for a new definition of neuropathy target esterase
Chemico-Biological Interactions 119-120: 541
Monroy-Noyola A, Sogorb MA, Vilanova E (1999)
Enzyme concentration as an important factor in the in vitro testing of the stereospecificity of the enzymatic hydrolysis of organophosphorus compounds
Toxicol In Vitro 13: 689
Monroy-Noyola A, Sogorb MA, Diaz-Alejo N, Niguez N, Barril J, Vicedo JL, Escudero MA, Vilanova E (1999)
Dichlorophenyl phosphoramidates as substrates for avian and mammalian liver phosphotriesterases: activity levels, calcium dependence and stereospecificity
Chemico-Biological Interactions 119-120: 257
Sogorb MA, Sanchez I, Lopez-Rivadulla M, Cespedes V, Vilanova E (1999)
EDTA-resistant and sensitive phosphotriesterase activities associated with albumin and lipoproteins in rabbit serum
Drug Metabolism & Disposition: The Biological Fate of Chemicals 27: 53
Vilanova E, Sogorb MA (1999)
The role of phosphotriesterases in the detoxication of organophosphorus compounds
Crit Rev Toxicol 29: 21
Vilanova E, Escudero MA, Barril J (1999)
NTE soluble isoforms: new perspectives for targets of neuropathy inducers and promoters
Chemico-Biological Interactions 119-120: 525
Diaz-Alejo N, Monroy A, Vilanova E, Vicedo JL, Sogorb MA (1998)
A stereospecific phosphotriesterase in hen liver and brain
Chemico-Biological Interactions 108: 187
Sogorb MA, Diaz-Alejo N, Escudero MA, Vilanova E (1998)
Phosphotriesterase activity identified in purified serum albumins
Archives of Toxicology 72: 219
Sogorb MA, Monroy A, Vilanova E (1998)
Chicken serum albumin hydrolyzes dichlorophenyl phosphoramidates by a mechanism based on transient phosphorylation
Chemical Research in Toxicology 11: 1441
Barril J, Vilanova E (1997)
Reversible inhibition can profoundly mislead studies on progressive inhibition of enzymes: the interaction of paraoxon with soluble neuropathy target esterase
Chemico-Biological Interactions 108: 19
Cespedes MV, Escudero MA, Barril J, Sogorb MA, Vicedo JL, Vilanova E (1997)
Discrimination of carboxylesterases of chicken neural tissue by inhibition with a neuropathic, non-neuropathic organophosphorus compounds and neuropathy promoter
Chemico-Biological Interactions 106: 191
Escudero MA, Cespedes MV, Vilanova E (1997)
Chromatographic discrimination of soluble neuropathy target esterase isoenzymes and related phenyl valerate esterases from chicken brain, spinal cord, and sciatic nerve
Journal of Neurochemistry 68: 2170
Escudero MA, Vilanova E (1997)
Purification and characterization of naturally soluble neuropathy target esterase from chicken sciatic nerve by HPLC and western blot
Journal of Neurochemistry 69: 1975
Sogorb MA, Bas S, Gutierrez LM, Vilanova E, Viniegra S (1997)
Bovine chromaffin cells as in vitro model for the study of non-cholinergic toxic effects of organophosphorus compounds
Archives of Toxicology Suppl 19: 347
Sogorb MA, Diaz-Alejo N, Pellin MC, Vilanova E (1997)
Inhibition and aging of neuropathy target esterase by the stereoisomers of a phosphoramidate related to methamidophos
Toxicol Lett 93: 95
Escudero MA, Sogorb MA, Vilanova E (1996)
An automatable microassay for phenyl valerate esterase activities sensitive to organophosphorus compounds
Toxicol Lett 89: 241
Gutierrez LM, Sogorb MA, Vilanova E, Viniegra S (1996)
The role of nicotinic receptors and calcium channels in mipafox induced inhibition of catecholamine release in bovine chromaffin cells
Environ Toxicol Pharmacol 1: 241
Sogorb MA, Vilanova E, Quintanar JL, Viniegra S (1996)
Bovine chromaffin cells in culture show carboxylesterase activities sensitive to organophosphorus compounds
International Journal of Biochemistry & Cell Biology 28: 983
Barril J, Tormo N, Diaz-Alejo N, Vilanova E (1995)
Organophosphorus inhibition and heat inactivation kinetics of particulate and soluble forms of peripheral nerve neuropathy target esterase
Journal of Biochemical Toxicology 10: 211
Escudero MA, Barril J, Tormo N, Vilanova E (1995)
Separation of two forms of neuropathy target esterase in the soluble fraction of the hen sciatic nerve
Chemico-Biological Interactions 97: 247
Carrera V, Diaz-Alejo N, Sogorb MA, Vicedo JL, Vilanova E (1994)
In vivo inhibition by mipafox of soluble and particulate forms of organophosphorus neuropathy target esterase (NTE) in hen sciatic nerve
Toxicol Lett 71: 47
Diaz-Alejo N, Sogorb MA, Vicedo JL, Barril J, Vilanova E (1994)
Non-calcium dependent activity hydrolysing organophosphorus compounds in hen plasma
Comparative Biochemistry & Physiology C Pharmacology Toxicology & Endocrinology 107: 213
Sogorb MA, Viniegra S, Reig JA, Vilanova E (1994)
Partial characterization of neuropathy target esterase and related phenyl valerate esterases from bovine adrenal medulla
Journal of Biochemical Toxicology 9: 145
Diaz-Alejo N, Vilanova E (1993)
Chiral high-performance liquid chromatography and gas chromatography of the stereoisomers of hexyl 2,5-dichlorophenyl phosphoramidate
Journal of Chromatography 622: 179
Sogorb MA, Diaz-Alejo N, Vilanova E, Vicedo JL, Carrera V (1993)
Effect of some metallic cations and organic compounds on the O-hexyl O-2,5-dichlorophenyl phosphoramidate hydrolysing activity in hen plasma
Archives of Toxicology 67: 416
Sogorb MA, Vilanova E, Diaz-Alejo N (1993)
The kinetics of O-hexyl O-2,5-dichlorophenyl phosphoramidate hydrolysing activity in hen plasma
Chemico-Biological Interactions 87: 117
Tormo N, Gimeno JR, Sogorb MA, Diaz-Alejo N, Vilanova E (1993)
Soluble and particulate organophosphorus neuropathy target esterase in brain and sciatic nerve of the hen, cat, rat, and chick
Journal of Neurochemistry 61: 2164
Vicedo JL, Carrera V, Barril J, Vilanova E (1993)
Properties of partly preinhibited hen brain neuropathy target esterase
Chemico-Biological Interactions 87: 417
Vilanova E, Barril J, Carrera V (1993)
Biochemical properties and possible toxicological significance of various forms of NTE
Chemico-Biological Interactions 87: 369
Carrera V, Barril J, Mauricio M, Pellin M, Vilanova E (1992)
Local application of neuropathic organophosphorus compounds to hen sciatic nerve: inhibition of neuropathy target esterase and peripheral neurological impairments
Toxicol Appl Pharmacol 117: 218
Johnson MK, Vilanova E, Read DJ (1991)
Anomalous biochemical responses in tests of the delayed neuropathic potential of methamidophos (O,S-dimethyl phosphorothioamidate), its resolved isomers and of some higher O-alkyl homologues
Archives of Toxicology 65: 618
Diaz-Alejo N, Pellin MC, Vicedo JL, Vilanova E (1990)
Hen liver and plasma can metabolize hexyl-DCP phosphoramidate at a rate comparable to that of rat
Neurotoxicology & Teratology 12: 615
Pellin MC, Moretto A, Lotti M, Vilanova E (1990)
Distribution and some biochemical properties of rat paraoxonase activity
Neurotoxicology & Teratology 12: 611
Vilanova E, Barril J, Carrera V, Pellin MC (1990)
Soluble and particulate forms of the organophosphorus neuropathy target esterase in hen sciatic nerve
Journal of Neurochemistry 55: 1258
Johnson MK, Vilanova E, Read DJ (1989)
Biochemical and clinical tests of the delayed neuropathic potential of some O-alkyl O-dichlorophenyl phosphoramidate analogues of methamidophos (O,S-dimethyl phosphorothioamidate)
Toxicology 54: 89
Barril JB, Vilanova E, Pellin MC (1988)
Sciatic nerve neuropathy target esterase. Methods of assay, proximo-distal distribution and regeneration
Toxicology 49: 107
Pellin MC, Vilanova E, Barril J (1988)
Low non-neuropathic tri-o-cresyl phosphate (TOCP) doses inhibit neuropathy target esterase near the neuropathic threshold in n-hexane pretreated hens
Toxicology 49: 99
Pellin M, Vicedo JL, Vilanova E (1987)
Sensitivity to tri-o-cresylphosphate neurotoxicity on n-hexane exposed hens as a model of simultaneous hexacarbon solvent and organophosphorus occupational intoxication
Archives of Toxicology 59: 311
Vilanova E, Johnson MK, Vicedo JL (1987)
Interaction of some unsubstituted phosphoramidate analogs of methamidophos (O,S-dimethyl phosphorothioamidate) with acetylcholinesterase and neuropathy target esterase of hen brain
Pesticide Biochemistry and Physiology 28: 224
Vicedo JL, Pellin M, Vilanova E (1985)
Phthalates and organophosphorus compounds as cholinesterase inhibitors in fractions of industrial hexane impurities
Archives of Toxicology 57: 46
Vilanova E, Vicedo JL (1984)
Poster 66. Properties of cholinesterase inhibitors of some fractions isolated from impurities of industrial solvents causing neuropathies
In: Cholinesterases, fundamental and applied aspects : proceedings of the Second International Meeting on Cholinesterases (Brzin M, Barnard EA, Sket D, Eds) De Gruyter:
Vilanova E, Vicedo JL (1983)
Serum cholinesterase inhibitors in the commercial hexane impurities
Archives of Toxicology 53: 59