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Family Report for: A85-EsteraseD-FGH

A85-EsteraseD-FGH



Relationship
Block X
Parent Family : Antigen85c

Comment
This family contains EC 3.1.2.12, human Esterase D and bacterial S-formylglutathione hydrolase. A universal pathway for formaldehyde detoxification. Corresponds to a subset of the Carbohydrate Esterase family CE1 in CAZy - Carbohydrate-Active enZYmes database (CE_1). Arabidopsis thaliana (Mouse-ear cress) serine esterase s-formylglutathione hydrolase SFGH is insensitive to organophosphate. Family TE22 in ThYme database

Database
Sequences
Interpro
|
IPR000801 (Esterase_put), IPR014186 (S-formylglutathione_hydrol)
PIRSF
|
Pdoc
|
PFam
|
PF00756 (Esterase)
Prints
|
Prosite
|
EC at KEGG
|
EC at EXPASY
|


Peptide in
|Fasta
Nucleotide in
|Fasta
Alignment with Multalin
|Text only/graphic display
Seed alignment with MAFFT
|No colour/coloured with Mview
Alignment with MAFFT
|No colour/coloured with Mview
Dendrogram
|Graphical display, obtained with the dnd file produced by Clustalw

References
8 more
    Title: The structure of a putative S-formylglutathione hydrolase from Agrobacterium tumefaciens
    van Straaten KE, Gonzalez CF, Valladares RB, Xu X, Savchenko AV, Sanders DA
    Ref: Protein Science, 18:2196, 2009 : PubMed

            

    Title: The crystal structure of the estA protein, a virulence factor from Streptococcus pneumoniae
    Kim MH, Kang BS, Kim S, Kim KJ, Lee CH, Oh BC, Park SC, Oh TK
    Ref: Proteins, 70:578, 2008 : PubMed

            

    Title: Structural characterization and reversal of the natural organophosphate resistance of a D-type esterase, Saccharomyces cerevisiae S-formylglutathione hydrolase
    Legler PM, Kumaran D, Swaminathan S, Studier FW, Millard CB
    Ref: Biochemistry, 47:9592, 2008 : PubMed

            

Other Papers


No structure scheme yet for this family

Structures in A85-EsteraseD-FGH family (21)

Genes Proteins in A85-EsteraseD-FGH family (580)

Fragments of genes in A85-EsteraseD-FGH family (27)

Substrates of some enzymes in the A85-EsteraseD-FGH family (7)

Inhibitors of some enzymes in the A85-EsteraseD-FGH family (6)



Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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