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Family Report for: Haloperoxidase

Haloperoxidase



Relationship
Block X
Parent Family : Abhydrolase_6

Comment
Non-heme Peroxidase. Bacterial and fungi non-heme bromo- and chloro-peroxidases family. Haloperoxidases catalyze the halogenation of organic compounds in the presence of halide ions and peroxides such as H2O2. They are named after the most electronegative halide they are able to oxidize and are classified according to their cofactor dependence as heme-type, vanadium-dependent and metal-free haloperoxidases (WARNING Only metal free haloperoxidases are alpha beta hydrolases with a Ser-His-Asp catalytic triad in the active center. This family contains also homologous arylesterases.)

Database
Sequences
Interpro
|
IPR000073 (Alpha/beta hydrolase fold-1)
PIRSF
|
Pdoc
|
PFam
|
PF12697 (Abhydrolase_6)
Prints
|
Prosite
|
EC at KEGG
|
EC at EXPASY
|


Peptide in
|Fasta
Nucleotide in
|Fasta
Alignment with Multalin
|Text only/graphic display
Seed alignment with MAFFT
|No colour/coloured with Mview
Alignment with MAFFT
|No colour/coloured with Mview
Dendrogram
|Graphical display, obtained with the dnd file produced by Clustalw

References
4 more
    Title: Different active-site loop orientation in serine hydrolases versus acyltransferases
    Jiang Y, Morley KL, Schrag JD, Kazlauskas RJ
    Ref: Chembiochem, 12:768, 2011 : PubMed

            

    Title: Switching catalysis from hydrolysis to perhydrolysis in Pseudomonas fluorescens esterase
    Yin DL, Bernhardt P, Morley KL, Jiang Y, Cheeseman JD, Purpero V, Schrag JD, Kazlauskas RJ
    Ref: Biochemistry, 49:1931, 2010 : PubMed

            

    Title: Structural investigation of the cofactor-free chloroperoxidases
    Hofmann B, Tolzer S, Pelletier I, Altenbuchner J, van Pee KH, Hecht HJ
    Ref: Journal of Molecular Biology, 279:889, 1998 : PubMed

            

Other Papers


Structure scheme for Haloperoxidase

Structures in Haloperoxidase family (28)

Genes Proteins in Haloperoxidase family (422)

Fragments of genes in Haloperoxidase family (12)

Substrates of some enzymes in the Haloperoxidase family (1)

Inhibitors of some enzymes in the Haloperoxidase family (3)



Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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