Lipase_2
Comment
Previously included in Fungal_triacylglycerol_lipase. This group of lipases has been called class 2 as they are not clearly related to other lipase families, and includes LipA and LipB from Bacillus subtilis and uncharacterised proteins from Caenorhabditis. Two other subfamilies described in: Arpigny and Jaeger (1999), Jaeger and Eggert (Family I.4 and Family I.7) are included in Lipase_2 (see classification). A novel type of hydrolase purified from Paucimonas revealed an unusual substrate specificity for amorphous poly((R)-3-hydroxyalkanoates PHA and no homologies to any other PHB depolymerase. A new family was built and extracted form Lipase_2 PHAZ7_phb_depolymerase (Arpigny_Jaeger Family IX)Database
Interpro : IPR002918 Lipase EstA\/Esterase EstB
PIRSF : No PIRSF
Pdoc : No Pdoc
Pfam : PF01674 Lipase_2
Prints : No Print
EC Number : No EC Number
References (6)
| Title : Biophysical characterization of mutants of Bacillus subtilis lipase evolved for thermostability: factors contributing to increased activity retention - Augustyniak_2012_Protein.Sci_21_487 |
| Author(s) : Augustyniak W , Brzezinska AA , Pijning T , Wienk H , Boelens R , Dijkstra BW , Reetz MT |
| Ref : Protein Science , 21 :487 , 2012 |
| Abstract : Augustyniak_2012_Protein.Sci_21_487 |
| ESTHER : Augustyniak_2012_Protein.Sci_21_487 |
| PubMedSearch : Augustyniak_2012_Protein.Sci_21_487 |
| PubMedID: 22267088 |
| Gene_locus related to this paper: bacsu-lip |
| Title : Structural basis of selection and thermostability of laboratory evolved Bacillus subtilis lipase - Acharya_2004_J.Mol.Biol_341_1271 |
| Author(s) : Acharya P , Rajakumara E , Sankaranarayanan R , Rao NM |
| Ref : Journal of Molecular Biology , 341 :1271 , 2004 |
| Abstract : Acharya_2004_J.Mol.Biol_341_1271 |
| ESTHER : Acharya_2004_J.Mol.Biol_341_1271 |
| PubMedSearch : Acharya_2004_J.Mol.Biol_341_1271 |
| PubMedID: 15321721 |
| Gene_locus related to this paper: bacsu-lip |
| Title : Lipases for biotechnology - Jaeger_2002_Curr.Opin.Biotechnol_13_390 |
| Author(s) : Jaeger KE , Eggert T |
| Ref : Curr Opin Biotechnol , 13 :390 , 2002 |
| Abstract : Jaeger_2002_Curr.Opin.Biotechnol_13_390 |
| ESTHER : Jaeger_2002_Curr.Opin.Biotechnol_13_390 |
| PubMedSearch : Jaeger_2002_Curr.Opin.Biotechnol_13_390 |
| PubMedID: 12323363 |
| Title : Lipolytic enzymes LipA and LipB from Bacillus subtilis differ in regulation of gene expression, biochemical properties, and three-dimensional structure - Eggert_2001_FEBS.Lett_502_89 |
| Author(s) : Eggert T , van Pouderoyen G , Dijkstra BW , Jaeger KE |
| Ref : FEBS Letters , 502 :89 , 2001 |
| Abstract : Eggert_2001_FEBS.Lett_502_89 |
| ESTHER : Eggert_2001_FEBS.Lett_502_89 |
| PubMedSearch : Eggert_2001_FEBS.Lett_502_89 |
| PubMedID: 11583117 |
| Gene_locus related to this paper: bacsu-lip , bacsu-LIPB |
| Title : A new type of thermoalkalophilic hydrolase of Paucimonas lemoignei with high specificity for amorphous polyesters of short chain-length hydroxyalkanoic acids - Handrick_2001_J.Biol.Chem_276_36215 |
| Author(s) : Handrick R , Reinhardt S , Focarete ML , Scandola M , Adamus G , Kowalczuk M , Jendrossek D |
| Ref : Journal of Biological Chemistry , 276 :36215 , 2001 |
| Abstract : Handrick_2001_J.Biol.Chem_276_36215 |
| ESTHER : Handrick_2001_J.Biol.Chem_276_36215 |
| PubMedSearch : Handrick_2001_J.Biol.Chem_276_36215 |
| PubMedID: 11457823 |
| Gene_locus related to this paper: psele-PHAZ7 |
| Title : Bacterial lipolytic enzymes: classification and properties - Arpigny_1999_Biochem.J_343_177 |
| Author(s) : Arpigny JL , Jaeger KE |
| Ref : Biochemical Journal , 343 :177 , 1999 |
| Abstract : Arpigny_1999_Biochem.J_343_177 |
| ESTHER : Arpigny_1999_Biochem.J_343_177 |
| PubMedSearch : Arpigny_1999_Biochem.J_343_177 |
| PubMedID: 10493927 |
Structures (26)
Genes Proteins in Lipase_2 family (183)
Fragments of genes in Lipase_2 family (6)
Structures in Lipase_2 family (26)Substrates in Lipase_2 family (24)
Inhibitors in Lipase_2 family (2)