Lipoprotein_Lipase
Relationship
Comment
Lipoprotein lipase (LPL) is a key enzyme of lipid metabolism that hydrolyses triglycerides, providing free fatty acids for cells and affecting the maturation of circulating lipoproteins. The enzyme is thought to play a role in the development of obesity and atherosclerosis. Defects in LPL are a cause of familial chylomicronemia syndrome (or type I hyperlipoproteinemia) and also of a form of deficiency characterised by hypertriglyceridemia. Familial chylomicronemia is a recessive disorder usually manifesting in childhood. On a normal diet, patients often present with abdominal pain, hepatosplenomegaly, lipemia retinalis, eruptive xanthomata, and massive hypertriglyceridemia, sometimes complicated with acute pancreatitis. Endothelial lipase (encoded by the LIPG gene) regulates the circulating level of high density lipoprotein cholesterol (HDL-C). It can also form a molecular bridge between endothelial cells and lipoproteins or circulating macrophages through interaction with heparan sulfate proteoglycans. This nonenzymatic action can increase cellular lipoprotein uptake and monocyte adhesion and contribute to atherosclerosis. LPL is a secreted glycoprotein that contains five disulfide bonds and requires an endoplasmic reticulum (ER) protein, lipase maturation factor 1 (LMF1), to successfully fold and traffic out of the ER to the Golgi. LPL is sorted into vesicles in an inactive state: helical LPL oligomer. LPL secretion is mediated by Syndecan-1 (SDC1), a heparan sulfate proteoglycan (HSPG). Stored LPL can be secreted into the interstitial space, where it interacts with HSPGs that bind to the multiple heparin binding sites on each LPL molecule . LPL is next bound by glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 (GPIHBP1) and transported into the capillary, where it acts on chylomicrons and very-low-density lipoproteins (VLDLs) to hydrolyze packaged triglycerides and release FFAs. The angiopoietin-like (ANGPTL) family of proteins inhibit LPL in different tissues. Leth-Espensen et al. publish that the intrinsic instability of the hydrolase domain of lipoprotein lipase facilitates its inactivation by ANGPTL4-catalyzed unfolding. Inverse effects of APOC2 and ANGPTL4 on the conformational dynamics of lid-anchoring structures in lipoprotein lipase is published by Kumari et al.Database
Interpro : IPR000734 Lipase , IPR002330 Lipoprotein lipase , IPR016272 Lipase, LIPH-type , IPR013818 Lipase
PIRSF : No PIRSF
Pdoc : PDOC00110
Pfam : PF00151 Lipase
Prints : PR00821 , PR00822
EC Number : 3.1.1.34
References (30)
| Title : The GPIHBP1-LPL complex and its role in plasma triglyceride metabolism: Insights into chylomicronemia - Jiang_2023_Biomed.Pharmacother_169_115874 |
| Author(s) : Jiang S , Ren Z , Yang Y , Liu Q , Zhou S , Xiao Y |
| Ref : Biomed Pharmacother , 169 :115874 , 2023 |
| Abstract : Jiang_2023_Biomed.Pharmacother_169_115874 |
| ESTHER : Jiang_2023_Biomed.Pharmacother_169_115874 |
| PubMedSearch : Jiang_2023_Biomed.Pharmacother_169_115874 |
| PubMedID: 37951027 |
| Title : The lipoprotein lipase that is shuttled into capillaries by GPIHBP1 enters the glycocalyx where it mediates lipoprotein processing - Song_2023_Proc.Natl.Acad.Sci.U.S.A_120_e2313825120 |
| Author(s) : Song W , Beigneux AP , Weston TA , Chen K , Yang Y , Nguyen LP , Guagliardo P , Jung H , Tran AP , Tu Y , Tran C , Birrane G , Miyashita K , Nakajima K , Murakami M , Tontonoz P , Jiang H , Ploug M , Fong LG , Young SG |
| Ref : Proc Natl Acad Sci U S A , 120 :e2313825120 , 2023 |
| Abstract : Song_2023_Proc.Natl.Acad.Sci.U.S.A_120_e2313825120 |
| ESTHER : Song_2023_Proc.Natl.Acad.Sci.U.S.A_120_e2313825120 |
| PubMedSearch : Song_2023_Proc.Natl.Acad.Sci.U.S.A_120_e2313825120 |
| PubMedID: 37871217 |
| Title : Angiopoietin-like protein 8: a multifaceted protein instrumental in regulating triglyceride metabolism - Wen_2023_Curr.Opin.Lipidol__ |
| Author(s) : Wen Y , Chen YQ , Konrad RJ |
| Ref : Curr Opin Lipidol , : , 2023 |
| Abstract : Wen_2023_Curr.Opin.Lipidol__ |
| ESTHER : Wen_2023_Curr.Opin.Lipidol__ |
| PubMedSearch : Wen_2023_Curr.Opin.Lipidol__ |
| PubMedID: 37962908 |
| Title : Inverse effects of APOC2 and ANGPTL4 on the conformational dynamics of lid-anchoring structures in lipoprotein lipase - Kumari_2023_Proc.Natl.Acad.Sci.U.S.A_120_e2221888120 |
| Author(s) : Kumari A , Gronnemose AL , Kristensen KK , Winther AL , Young SG , Jorgensen TJD , Ploug M |
| Ref : Proc Natl Acad Sci U S A , 120 :e2221888120 , 2023 |
| Abstract : Kumari_2023_Proc.Natl.Acad.Sci.U.S.A_120_e2221888120 |
| ESTHER : Kumari_2023_Proc.Natl.Acad.Sci.U.S.A_120_e2221888120 |
| PubMedSearch : Kumari_2023_Proc.Natl.Acad.Sci.U.S.A_120_e2221888120 |
| PubMedID: 37094117 |
| Gene_locus related to this paper: human-LPL |
| Title : Transcriptome-wide association study reveals cholesterol metabolism gene Lpl is a key regulator of cognitive dysfunction - Hu_2022_Front.Mol.Neurosci_15_1044022 |
| Author(s) : Hu W , Liu J , Hu Y , Xu Q , Deng T , Wei M , Lu L , Mi J , Bergquist J , Xu F , Tian G |
| Ref : Front Mol Neurosci , 15 :1044022 , 2022 |
| Abstract : Hu_2022_Front.Mol.Neurosci_15_1044022 |
| ESTHER : Hu_2022_Front.Mol.Neurosci_15_1044022 |
| PubMedSearch : Hu_2022_Front.Mol.Neurosci_15_1044022 |
| PubMedID: 36590920 |
| Title : Lipoprotein Lipase and Its Regulators: An Unfolding Story - Wu_2021_Trends.Endocrinol.Metab_32_48 |
| Author(s) : Wu SA , Kersten S , Qi L |
| Ref : Trends Endocrinol Metab , 32 :48 , 2021 |
| Abstract : Wu_2021_Trends.Endocrinol.Metab_32_48 |
| ESTHER : Wu_2021_Trends.Endocrinol.Metab_32_48 |
| PubMedSearch : Wu_2021_Trends.Endocrinol.Metab_32_48 |
| PubMedID: 33277156 |
| Gene_locus related to this paper: human-LPL |
| Title : The intrinsic instability of the hydrolase domain of lipoprotein lipase facilitates its inactivation by ANGPTL4-catalyzed unfolding - Leth-Espensen_2021_Proc.Natl.Acad.Sci.U.S.A_118_e2026650118 |
| Author(s) : Leth-Espensen KZ , Kristensen KK , Kumari A , Winther AL , Young SG , Jorgensen TJD , Ploug M |
| Ref : Proc Natl Acad Sci U S A , 118 : , 2021 |
| Abstract : Leth-Espensen_2021_Proc.Natl.Acad.Sci.U.S.A_118_e2026650118 |
| ESTHER : Leth-Espensen_2021_Proc.Natl.Acad.Sci.U.S.A_118_e2026650118 |
| PubMedSearch : Leth-Espensen_2021_Proc.Natl.Acad.Sci.U.S.A_118_e2026650118 |
| PubMedID: 33723082 |
| Gene_locus related to this paper: human-LPL |
| Title : The structure of helical lipoprotein lipase reveals an unexpected twist in lipase storage - Gunn_2020_Proc.Natl.Acad.Sci.U.S.A_117_10254 |
| Author(s) : Gunn KH , Roberts BS , Wang F , Strauss JD , Borgnia MJ , Egelman EH , Neher SB |
| Ref : Proc Natl Acad Sci U S A , 117 :10254 , 2020 |
| Abstract : Gunn_2020_Proc.Natl.Acad.Sci.U.S.A_117_10254 |
| ESTHER : Gunn_2020_Proc.Natl.Acad.Sci.U.S.A_117_10254 |
| PubMedSearch : Gunn_2020_Proc.Natl.Acad.Sci.U.S.A_117_10254 |
| PubMedID: 32332168 |
| Gene_locus related to this paper: bovin-lipli , human-LPL |
| Title : Structure of lipoprotein lipase in complex with GPIHBP1 - Arora_2019_Proc.Natl.Acad.Sci.U.S.A_116_10360 |
| Author(s) : Arora R , Nimonkar AV , Baird D , Wang C , Chiu CH , Horton PA , Hanrahan S , Cubbon R , Weldon S , Tschantz WR , Mueller S , Brunner R , Lehr P , Meier P , Ottl J , Voznesensky A , Pandey P , Smith TM , Stojanovic A , Flyer A , Benson TE , Romanowski MJ , Trauger JW |
| Ref : Proc Natl Acad Sci U S A , 116 :10360 , 2019 |
| Abstract : Arora_2019_Proc.Natl.Acad.Sci.U.S.A_116_10360 |
| ESTHER : Arora_2019_Proc.Natl.Acad.Sci.U.S.A_116_10360 |
| PubMedSearch : Arora_2019_Proc.Natl.Acad.Sci.U.S.A_116_10360 |
| PubMedID: 31072929 |
| Gene_locus related to this paper: human-LPL |
| Title : Structure of the lipoprotein lipase-GPIHBP1 complex that mediates plasma triglyceride hydrolysis - Birrane_2019_Proc.Natl.Acad.Sci.U.S.A_116_1723 |
| Author(s) : Birrane G , Beigneux AP , Dwyer B , Strack-Logue B , Kristensen KK , Francone OL , Fong LG , Mertens HDT , Pan CQ , Ploug M , Young SG , Meiyappan M |
| Ref : Proc Natl Acad Sci U S A , 116 :1723 , 2019 |
| Abstract : Birrane_2019_Proc.Natl.Acad.Sci.U.S.A_116_1723 |
| ESTHER : Birrane_2019_Proc.Natl.Acad.Sci.U.S.A_116_1723 |
| PubMedSearch : Birrane_2019_Proc.Natl.Acad.Sci.U.S.A_116_1723 |
| PubMedID: 30559189 |
| Gene_locus related to this paper: human-LPL |
| Title : GPIHBP1 and Lipoprotein Lipase, Partners in Plasma Triglyceride Metabolism - Young_2019_Cell.Metab_30_51 |
| Author(s) : Young SG , Fong LG , Beigneux AP , Allan CM , He C , Jiang H , Nakajima K , Meiyappan M , Birrane G , Ploug M |
| Ref : Cell Metab , 30 :51 , 2019 |
| Abstract : Young_2019_Cell.Metab_30_51 |
| ESTHER : Young_2019_Cell.Metab_30_51 |
| PubMedSearch : Young_2019_Cell.Metab_30_51 |
| PubMedID: 31269429 |
| Gene_locus related to this paper: human-LPL |
| Title : GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients - Hu_2019_Elife_8_e47178 |
| Author(s) : Hu X , Matsumoto K , Jung RS , Weston TA , Heizer PJ , He C , Sandoval NP , Allan CM , Tu Y , Vinters HV , Liau LM , Ellison RM , Morales JE , Baufeld LJ , Bayley NA , He L , Betsholtz C , Beigneux AP , Nathanson DA , Gerhardt H , Young SG , Fong LG , Jiang H |
| Ref : Elife , 8 : , 2019 |
| Abstract : Hu_2019_Elife_8_e47178 |
| ESTHER : Hu_2019_Elife_8_e47178 |
| PubMedSearch : Hu_2019_Elife_8_e47178 |
| PubMedID: 31169500 |
| Title : A disordered acidic domain in GPIHBP1 harboring a sulfated tyrosine regulates lipoprotein lipase - Kristensen_2018_Proc.Natl.Acad.Sci.U.S.A_115_E6020 |
| Author(s) : Kristensen KK , Midtgaard SR , Mysling S , Kovrov O , Hansen LB , Skar-Gislinge N , Beigneux AP , Kragelund BB , Olivecrona G , Young SG , Jorgensen TJD , Fong LG , Ploug M |
| Ref : Proc Natl Acad Sci U S A , 115 :E6020 , 2018 |
| Abstract : Kristensen_2018_Proc.Natl.Acad.Sci.U.S.A_115_E6020 |
| ESTHER : Kristensen_2018_Proc.Natl.Acad.Sci.U.S.A_115_E6020 |
| PubMedSearch : Kristensen_2018_Proc.Natl.Acad.Sci.U.S.A_115_E6020 |
| PubMedID: 29899144 |
| Title : Mobility of HSPG-bound LPL explains how LPL is able to reach GPIHBP1 on capillaries - Allan_2017_J.Lipid.Res_58_216 |
| Author(s) : Allan CM , Larsson M , Jung RS , Ploug M , Bensadoun A , Beigneux AP , Fong LG , Young SG |
| Ref : J Lipid Res , 58 :216 , 2017 |
| Abstract : Allan_2017_J.Lipid.Res_58_216 |
| ESTHER : Allan_2017_J.Lipid.Res_58_216 |
| PubMedSearch : Allan_2017_J.Lipid.Res_58_216 |
| PubMedID: 27811232 |
| Title : The acidic domain of the endothelial membrane protein GPIHBP1 stabilizes lipoprotein lipase activity by preventing unfolding of its catalytic domain - Mysling_2016_Elife_5_e12095 |
| Author(s) : Mysling S , Kristensen KK , Larsson M , Beigneux AP , Gardsvoll H , Loren FG , Bensadouen A , Jorgensen TJ , Young SG , Ploug M |
| Ref : Elife , 5 : , 2016 |
| Abstract : Mysling_2016_Elife_5_e12095 |
| ESTHER : Mysling_2016_Elife_5_e12095 |
| PubMedSearch : Mysling_2016_Elife_5_e12095 |
| PubMedID: 26725083 |
| Title : GPIHBP1 missense mutations often cause multimerization of GPIHBP1 and thereby prevent lipoprotein lipase binding - Beigneux_2015_Circ.Res_116_624 |
| Author(s) : Beigneux AP , Fong LG , Bensadoun A , Davies BS , Oberer M , Gardsvoll H , Ploug M , Young SG |
| Ref : Circulation Research , 116 :624 , 2015 |
| Abstract : Beigneux_2015_Circ.Res_116_624 |
| ESTHER : Beigneux_2015_Circ.Res_116_624 |
| PubMedSearch : Beigneux_2015_Circ.Res_116_624 |
| PubMedID: 25387803 |
| Title : Hippocampal lipoprotein lipase regulates energy balance in rodents - Picard_2014_Mol.Metab_3_167 |
| Author(s) : Picard A , Rouch C , Kassis N , Moulle VS , Croizier S , Denis RG , Castel J , Coant N , Davis K , Clegg DJ , Benoit SC , Prevot V , Bouret S , Luquet S , Le Stunff H , Cruciani-Guglielmacci C , Magnan C |
| Ref : Mol Metab , 3 :167 , 2014 |
| Abstract : Picard_2014_Mol.Metab_3_167 |
| ESTHER : Picard_2014_Mol.Metab_3_167 |
| PubMedSearch : Picard_2014_Mol.Metab_3_167 |
| PubMedID: 24634821 |
| Title : The GPIHBP1-LPL complex is responsible for the margination of triglyceride-rich lipoproteins in capillaries - Goulbourne_2014_Cell.Metab_19_849 |
| Author(s) : Goulbourne CN , Gin P , Tatar A , Nobumori C , Hoenger A , Jiang H , Grovenor CR , Adeyo O , Esko JD , Goldberg IJ , Reue K , Tontonoz P , Bensadoun A , Beigneux AP , Young SG , Fong LG |
| Ref : Cell Metab , 19 :849 , 2014 |
| Abstract : Goulbourne_2014_Cell.Metab_19_849 |
| ESTHER : Goulbourne_2014_Cell.Metab_19_849 |
| PubMedSearch : Goulbourne_2014_Cell.Metab_19_849 |
| PubMedID: 24726386 |
| Title : Angiopoietin-like protein 4 inhibition of lipoprotein lipase: evidence for reversible complex formation - Lafferty_2013_J.Biol.Chem_288_28524 |
| Author(s) : Lafferty MJ , Bradford KC , Erie DA , Neher SB |
| Ref : Journal of Biological Chemistry , 288 :28524 , 2013 |
| Abstract : Lafferty_2013_J.Biol.Chem_288_28524 |
| ESTHER : Lafferty_2013_J.Biol.Chem_288_28524 |
| PubMedSearch : Lafferty_2013_J.Biol.Chem_288_28524 |
| PubMedID: 23960078 |
| Gene_locus related to this paper: human-LPL |
| Title : Assessing mechanisms of GPIHBP1 and lipoprotein lipase movement across endothelial cells - Davies_2012_J.Lipid.Res_53_2690 |
| Author(s) : Davies BS , Goulbourne CN , Barnes RH, 2nd , Turlo KA , Gin P , Vaughan S , Vaux DJ , Bensadoun A , Beigneux AP , Fong LG , Young SG |
| Ref : J Lipid Res , 53 :2690 , 2012 |
| Abstract : Davies_2012_J.Lipid.Res_53_2690 |
| ESTHER : Davies_2012_J.Lipid.Res_53_2690 |
| PubMedSearch : Davies_2012_J.Lipid.Res_53_2690 |
| PubMedID: 23008484 |
| Gene_locus related to this paper: human-LPL |
| Title : Mutations in lipoprotein lipase that block binding to the endothelial cell transporter GPIHBP1 - Voss_2011_Proc.Natl.Acad.Sci.U.S.A_108_7980 |
| Author(s) : Voss CV , Davies BS , Tat S , Gin P , Fong LG , Pelletier C , Mottler CD , Bensadoun A , Beigneux AP , Young SG |
| Ref : Proc Natl Acad Sci U S A , 108 :7980 , 2011 |
| Abstract : Voss_2011_Proc.Natl.Acad.Sci.U.S.A_108_7980 |
| ESTHER : Voss_2011_Proc.Natl.Acad.Sci.U.S.A_108_7980 |
| PubMedSearch : Voss_2011_Proc.Natl.Acad.Sci.U.S.A_108_7980 |
| PubMedID: 21518912 |
| Gene_locus related to this paper: human-LPL |
| Title : GPIHBP1 is responsible for the entry of lipoprotein lipase into capillaries - Davies_2010_Cell.Metab_12_42 |
| Author(s) : Davies BS , Beigneux AP , Barnes RH, 2nd , Tu Y , Gin P , Weinstein MM , Nobumori C , Nyren R , Goldberg I , Olivecrona G , Bensadoun A , Young SG , Fong LG |
| Ref : Cell Metab , 12 :42 , 2010 |
| Abstract : Davies_2010_Cell.Metab_12_42 |
| ESTHER : Davies_2010_Cell.Metab_12_42 |
| PubMedSearch : Davies_2010_Cell.Metab_12_42 |
| PubMedID: 20620994 |
| Title : Association of lipoprotein lipase D9N polymorphism with myocardial infarction in type 2 diabetes: the genetics, outcomes, and lipids in type 2 diabetes (GOLD) study - Izar_2009_Atherosclerosis_204_165 |
| Author(s) : Izar MC , Helfenstein T , Ihara SS , Relvas WG , Santos AO , Fischer SC , Pinto LE , Lopes IE , Pomaro DR , Fonseca MI , Bodanese LC , Moriguchi EH , Saraiva JF , Introcaso L , Souza AD , Scartezini M , Torres KP , Zagury L , Jardim PC , Costa EA , Tacito LH , Forti A , Magalhaes ME , Chacra AR , Bertolami MC , Loures-Vale AA , Barros MA , Xavier HT , Lyra R , Argamanijan D , Guimaraes A , Novazzi JP , Kasinski N , Afiune A , Martinez TL , Santos RD , Nicolau JC , Cesar LA , Povoa RM , Carvalho AC , Han SW , Fonseca FA |
| Ref : Atherosclerosis , 204 :165 , 2009 |
| Abstract : Izar_2009_Atherosclerosis_204_165 |
| ESTHER : Izar_2009_Atherosclerosis_204_165 |
| PubMedSearch : Izar_2009_Atherosclerosis_204_165 |
| PubMedID: 18823627 |
| Gene_locus related to this paper: human-LPL |
| Title : Cloning of a unique lipase from endothelial cells extends the lipase gene family. - |
| Author(s) : Hirata K , Dichek HL , Cioffi JA , Choi SY , Leeper NJ , Quintana L , Kronmal GS , Cooper AD , Quertermous T |
| Ref : Journal of Biological Chemistry , 274 :14170 , 1999 |
| PubMedID: 10318835 |
| Gene_locus related to this paper: human-LIPG , mouse-Lipg |
| Title : A novel endothelial-derived lipase that modulates HDL metabolism - Jaye_1999_Nat.Genet_21_424 |
| Author(s) : Jaye M , Lynch KJ , Krawiec J , Marchadier D , Maugeais C , Doan K , South V , Amin D , Perrone M , Rader DJ |
| Ref : Nat Genet , 21 :424 , 1999 |
| Abstract : Jaye_1999_Nat.Genet_21_424 |
| ESTHER : Jaye_1999_Nat.Genet_21_424 |
| PubMedSearch : Jaye_1999_Nat.Genet_21_424 |
| PubMedID: 10192396 |
| Gene_locus related to this paper: human-LIPG |
| Title : Lipoprotein lipase. Molecular model based on the pancreatic lipase x-ray structure: consequences for heparin binding and catalysis - van Tilbeurgh_1994_J.Biol.Chem_269_4626 |
| Author(s) : van Tilbeurgh H , Roussel A , Lalouel JM , Cambillau C |
| Ref : Journal of Biological Chemistry , 269 :4626 , 1994 |
| Abstract : van Tilbeurgh_1994_J.Biol.Chem_269_4626 |
| ESTHER : van Tilbeurgh_1994_J.Biol.Chem_269_4626 |
| PubMedSearch : van Tilbeurgh_1994_J.Biol.Chem_269_4626 |
| PubMedID: 8308035 |
| Title : Lipoprotein lipase enhances the interaction of low density lipoproteins with artery-derived extracellular matrix proteoglycans - Edwards_1993_J.Lipid.Res_34_1155 |
| Author(s) : Edwards IJ , Goldberg IJ , Parks JS , Xu H , Wagner WD |
| Ref : J Lipid Res , 34 :1155 , 1993 |
| Abstract : Edwards_1993_J.Lipid.Res_34_1155 |
| ESTHER : Edwards_1993_J.Lipid.Res_34_1155 |
| PubMedSearch : Edwards_1993_J.Lipid.Res_34_1155 |
| PubMedID: 8371063 |
| Title : Lipoprotein lipase enhances binding of lipoproteins to heparan sulfate on cell surfaces and extracellular matrix - Eisenberg_1992_J.Clin.Invest_90_2013 |
| Author(s) : Eisenberg S , Sehayek E , Olivecrona T , Vlodavsky I |
| Ref : J Clinical Investigation , 90 :2013 , 1992 |
| Abstract : Eisenberg_1992_J.Clin.Invest_90_2013 |
| ESTHER : Eisenberg_1992_J.Clin.Invest_90_2013 |
| PubMedSearch : Eisenberg_1992_J.Clin.Invest_90_2013 |
| PubMedID: 1430223 |
| Title : A missense mutation at codon 188 of the human lipoprotein lipase gene is a frequent cause of lipoprotein lipase deficiency in persons of different ancestries - Monsalve_1990_J.Clin.Invest_86_728 |
| Author(s) : Monsalve MV , Henderson H , Roederer G , Julien P , Deeb S , Kastelein JJ , Peritz L , Devlin R , Bruin T , Murthy MR , et al. |
| Ref : J Clinical Investigation , 86 :728 , 1990 |
| Abstract : Monsalve_1990_J.Clin.Invest_86_728 |
| ESTHER : Monsalve_1990_J.Clin.Invest_86_728 |
| PubMedSearch : Monsalve_1990_J.Clin.Invest_86_728 |
| PubMedID: 1975597 |
| Gene_locus related to this paper: human-LPL |
| Title : Human lipoprotein lipase complementary DNA sequence - Wion_1987_Science_235_1638 |
| Author(s) : Wion KL , Kirchgessner TG , Lusis AJ , Schotz MC , Lawn RM |
| Ref : Science , 235 :1638 , 1987 |
| Abstract : Wion_1987_Science_235_1638 |
| ESTHER : Wion_1987_Science_235_1638 |
| PubMedSearch : Wion_1987_Science_235_1638 |
| PubMedID: 3823907 |
| Gene_locus related to this paper: human-LPL |
Structures (6)
Genes Proteins in Lipoprotein_Lipase family (318)
Fragments of genes in Lipoprotein_Lipase family (66)
Structures in Lipoprotein_Lipase family (6)Substrates in Lipoprotein_Lipase family (3)
Inhibitors in Lipoprotein_Lipase family (7)