Peptidase_S37
Relationship
Comment
This group of serine peptidases belong to MEROPS peptidase family S37 (clan SC). The members of this group of secreted peptidases are restricted to bacteria. In Streptomyces lividans the peptidase removes tripeptides from the N terminus of extracellular proteins (tripeptidyl aminopeptidase,Tap). The peptidase from Streptomyces mobaraensis has been shown to activate the transglutaminase precursor by removal of a leading tri- or tetrapeptide (Umezawa et al., 2004). Calcium ions enhance activity (Zotzel et al., 2003).Database
Interpro : IPR008761 Peptidase_S37 tripeptidyl aminopeptidase
PIRSF : No PIRSF
Pdoc : No Pdoc
Pfam : PF05576 Peptidase_S37
Prints : No Print
EC Number : No EC Number
References (2)
| Title : Novel prolyl tri\/tetra-peptidyl aminopeptidase from Streptomyces mobaraensis: substrate specificity and enzyme gene cloning - Umezawa_2004_J.Biochem_136_293 |
| Author(s) : Umezawa Y , Yokoyama K , Kikuchi Y , Date M , Ito K , Yoshimoto T , Matsui H |
| Ref : J Biochem , 136 :293 , 2004 |
| Abstract : Umezawa_2004_J.Biochem_136_293 |
| ESTHER : Umezawa_2004_J.Biochem_136_293 |
| PubMedSearch : Umezawa_2004_J.Biochem_136_293 |
| PubMedID: 15598885 |
| Gene_locus related to this paper: strmb-tpap |
| Title : Activated transglutaminase from Streptomyces mobaraensis is processed by a tripeptidyl aminopeptidase in the final step - Zotzel_2003_Eur.J.Biochem_270_4149 |
| Author(s) : Zotzel J , Pasternack R , Pelzer C , Ziegert D , Mainusch M , Fuchsbauer HL |
| Ref : European Journal of Biochemistry , 270 :4149 , 2003 |
| Abstract : Zotzel_2003_Eur.J.Biochem_270_4149 |
| ESTHER : Zotzel_2003_Eur.J.Biochem_270_4149 |
| PubMedSearch : Zotzel_2003_Eur.J.Biochem_270_4149 |
| PubMedID: 14519127 |
| Gene_locus related to this paper: strmb-tpap |
No structure scheme yet for this family
Genes Proteins in Peptidase_S37 family (802)
Fragments of genes in Peptidase_S37 family (44)
No fragment of genesNo substrate
Inhibitors in Peptidase_S37 family (1)