AcoC_BiotinLipoyl-ABH

Relationship

Block: X

Comment

This family groups proteins with an architecture composed of two or three domains: a Biotin_lipoyl domain, possibly a E3_binding domain and an alpha/beta hydrolase domain. PF00364. Biotin_lipoyl IPR000089. Biotin_lipoyl. Biotin/lipoyl attachment domain has a conserved lysine residue that binds biotin or lipoic acid. Biotin plays a catalytic role in some carboxyl transfer reactions and is covalently attached, via an amide bond, to a lysine residue in enzymes requiring this coenzyme. PF02817. E3_binding. IPR004167. E3-bd. is a small domain of the E2 subunit of 2-oxo-acid dehydrogenases (not an alpha beta hydrolase) that is responsible for the binding of the E3 subunit. Here dihydrolipoamide acetyltransferase (acoC) from the 2,3-butanediol catabolic pathway: acetyl-CoA:enzyme N6-(dihydrolipoyl)lysine S-acetyltransferase. Transfer of thio acetate from Acetyl-CoA to N6-(dihydrolipoyl)lysine of an enzyme

Database

Interpro : No interpro

PIRSF : No PIRSF

Pdoc : No Pdoc

Pfam : PF12697 Abhydrolase_6

Prints : No Print

EC Number : No EC Number

Sequences

Peptide in	Fasta
Nucleotide in	Fasta
Alignment with Multalin	Text only
Seed alignment with MAFFT	No colour
Alignment with MAFFT	No colour
Dendrogram	The dnd file

References (2)

Title : Molecular characterization of the Pseudomonas putida 2,3-butanediol catabolic pathway. - Huang_1994_FEMS.Microbiol.Lett_124_141

Author(s) : Huang M , Oppermann FB , Steinbuchel A

Ref : FEMS Microbiology Letters , 124 :141 , 1994

Abstract : Huang_1994_FEMS.Microbiol.Lett_124_141

ESTHER : Huang_1994_FEMS.Microbiol.Lett_124_141

PubMedSearch : Huang_1994_FEMS.Microbiol.Lett_124_141

PubMedID: 7813883

Gene_locus related to this paper: psepu-acoc

Title : Identification and molecular characterization of the Alcaligenes eutrophus H16 aco operon genes involved in acetoin catabolism - Priefert_1991_J.Bacteriol_173_4056

Author(s) : Priefert H , Hein S , Krueger N , Zeh K , Schmidt B , Steinbuechel A

Ref : Journal of Bacteriology , 173 :4056 , 1991

Abstract : Priefert_1991_J.Bacteriol_173_4056

ESTHER : Priefert_1991_J.Bacteriol_173_4056

PubMedSearch : Priefert_1991_J.Bacteriol_173_4056

PubMedID: 2061286

Gene_locus related to this paper: cupnh-acoc

No structure scheme yet for this family

Genes Proteins in AcoC_BiotinLipoyl-ABH family (42)

No fragment of genes

No substrate

No Inhibitor