Family

Go to basket

Tree Display

AceDB Schema

XML Display

Feedback

Family Report for: Arb2_FAM172A


Arb2_FAM172A



Relationship
Block X
Parent Family : Arb2


Comments

FAM172A plays an important role in the regulation of cotranscriptional alternative splicing by interacting with Ago2 (Argonaute-2) and Chd7. The FAM172A mutant mice display a complex phenotype mimicking both the major and minor features of CHARGE syndrome (Belanger et al.).



Database
Sequences
Interpro : IPR039929 (Cotranscriptional regulator FAM172A), IPR019154 (Arb2 domain)
PIRSF :
Pdoc :
PFam : PF09757 (Arb2)
Prints :
Prosite :
no EC number

Peptide in Fasta
Nucleotide in Fasta
Alignment with Multalin : Text only/graphic display
Seed alignment with MAFFT : No colour/coloured with Mview
Alignment with MAFFT : No colour/coloured with Mview
Dendrogram : Graphical display, obtained with the dnd file produced by Clustalw
HMM profile : HMM profile


No Image

No Structure

If the number of entries is too large in this family (>4000) or the page is too slow follow this link



No Substrate

No Inhibitor


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page
webmaster

Acknowledgements and disclaimer