Asp2
Comment
(from Interpro) Accessory Sec protein Asp2. Proteins in this entry form part of an accessory Sec system which is involved in the export of serine-rich repeat (SRR) glycoproteins important for virulence in a number of Gram-positive species, including Streptococcus gordonii and Staphylococcus aureus. Asp2 and Asp3 interact directly with GspB and may function in part as chaperones in the early phase of GspB transport. Asp2 is a bifunctional protein that is essential for both GspB transport and correct glycosylation. A subset of this family is XcbB_CpsF_sero familyDatabase
Interpro : IPR022267 Accessory Sec system protein Asp2
PIRSF : No PIRSF
Pdoc : No Pdoc
Pfam : PF16929 Asp2
Prints : No Print
EC Number : No EC Number
References (6)
| Title : Structural and functional insights into the Asp1\/2\/3 complex mediated secretion of pneumococcal serine-rich repeat protein PsrP - Guo_2020_Biochem.Biophys.Res.Commun_524_784 |
| Author(s) : Guo C , Feng Z , Zuo G , Jiang YL , Zhou CZ , Chen Y , Hou WT |
| Ref : Biochemical & Biophysical Research Communications , 524 :784 , 2020 |
| Abstract : Guo_2020_Biochem.Biophys.Res.Commun_524_784 |
| ESTHER : Guo_2020_Biochem.Biophys.Res.Commun_524_784 |
| PubMedSearch : Guo_2020_Biochem.Biophys.Res.Commun_524_784 |
| PubMedID: 32037091 |
| Gene_locus related to this paper: stree-a0a0b7mbs7 |
| Title : Differential localization of the streptococcal accessory sec components and implications for substrate export - Yen_2013_J.Bacteriol_195_682 |
| Author(s) : Yen YT , Cameron TA , Bensing BA , Seepersaud R , Zambryski PC , Sullam PM |
| Ref : Journal of Bacteriology , 195 :682 , 2013 |
| Abstract : Yen_2013_J.Bacteriol_195_682 |
| ESTHER : Yen_2013_J.Bacteriol_195_682 |
| PubMedSearch : Yen_2013_J.Bacteriol_195_682 |
| PubMedID: 23204472 |
| Title : Gap2 promotes the formation of a stable protein complex required for mature Fap1 biogenesis - Echlin_2013_J.Bacteriol_195_2166 |
| Author(s) : Echlin H , Zhu F , Li Y , Peng Z , Ruiz T , Bedwell GJ , Prevelige PE, Jr. , Wu H |
| Ref : Journal of Bacteriology , 195 :2166 , 2013 |
| Abstract : Echlin_2013_J.Bacteriol_195_2166 |
| ESTHER : Echlin_2013_J.Bacteriol_195_2166 |
| PubMedSearch : Echlin_2013_J.Bacteriol_195_2166 |
| PubMedID: 23475979 |
| Gene_locus related to this paper: 9stre-e7s950 |
| Title : The accessory Sec protein Asp2 modulates GlcNAc deposition onto the serine-rich repeat glycoprotein GspB - Seepersaud_2012_J.Bacteriol_194_5564 |
| Author(s) : Seepersaud R , Bensing BA , Yen YT , Sullam PM |
| Ref : Journal of Bacteriology , 194 :5564 , 2012 |
| Abstract : Seepersaud_2012_J.Bacteriol_194_5564 |
| ESTHER : Seepersaud_2012_J.Bacteriol_194_5564 |
| PubMedSearch : Seepersaud_2012_J.Bacteriol_194_5564 |
| PubMedID: 22885294 |
| Gene_locus related to this paper: strag-a0a076z217 , strgn-asp2 |
| Title : Asp2 and Asp3 interact directly with GspB, the export substrate of the Streptococcus gordonii accessory Sec System - Yen_2011_J.Bacteriol_193_3165 |
| Author(s) : Yen YT , Seepersaud R , Bensing BA , Sullam PM |
| Ref : Journal of Bacteriology , 193 :3165 , 2011 |
| Abstract : Yen_2011_J.Bacteriol_193_3165 |
| ESTHER : Yen_2011_J.Bacteriol_193_3165 |
| PubMedSearch : Yen_2011_J.Bacteriol_193_3165 |
| PubMedID: 21531800 |
| Gene_locus related to this paper: strgn-asp2 |
| Title : Genes in the accessory sec locus of Streptococcus gordonii have three functionally distinct effects on the expression of the platelet-binding protein GspB - Takamatsu_2004_Mol.Microbiol_52_189 |
| Author(s) : Takamatsu D , Bensing BA , Sullam PM |
| Ref : Molecular Microbiology , 52 :189 , 2004 |
| Abstract : Takamatsu_2004_Mol.Microbiol_52_189 |
| ESTHER : Takamatsu_2004_Mol.Microbiol_52_189 |
| PubMedSearch : Takamatsu_2004_Mol.Microbiol_52_189 |
| PubMedID: 15049820 |
| Gene_locus related to this paper: strgn-asp2 |
Structures (2)
Genes Proteins in Asp2 family (287)
Fragments of genes in Asp2 family (6)
Structures in Asp2 family (2)No substrate
No Inhibitor