Go to basket

Tree Display

AceDB Schema

XML Display


Family Report for: Asp2


Family Asp2
Block X
(from Interpro) Accessory Sec protein Asp2. Proteins in this entry form part of an accessory Sec system which is involved in the export of serine-rich repeat (SRR) glycoproteins important for virulence in a number of Gram-positive species, including Streptococcus gordonii and Staphylococcus aureus. Asp2 and Asp3 interact directly with GspB and may function in part as chaperones in the early phase of GspB transport. Asp2 is a bifunctional protein that is essential for both GspB transport and correct glycosylation

IPR022267 (Accessory Sec system protein Asp2)
PF16929 (Asp2)
no EC number

Peptide in
Nucleotide in
Alignment with Multalin
|Text only/graphic display
Seed alignment with MAFFT
|No colour/coloured with Mview
Alignment with MAFFT
|No colour/coloured with Mview
|Graphical display, obtained with the dnd file produced by Clustalw

2 more
    Title: Structural and functional insights into the Asp1/2/3 complex mediated secretion of pneumococcal serine-rich repeat protein PsrP
    Guo C, Feng Z, Zuo G, Jiang YL, Zhou CZ, Chen Y, Hou WT
    Ref: Biochemical & Biophysical Research Communications, 524:784, 2020 : PubMed


    Title: The accessory Sec protein Asp2 modulates GlcNAc deposition onto the serine-rich repeat glycoprotein GspB
    Seepersaud R, Bensing BA, Yen YT, Sullam PM
    Ref: Journal of Bacteriology, 194:5564, 2012 : PubMed


    Title: Asp2 and Asp3 interact directly with GspB, the export substrate of the Streptococcus gordonii accessory Sec System
    Yen YT, Seepersaud R, Bensing BA, Sullam PM
    Ref: Journal of Bacteriology, 193:3165, 2011 : PubMed


Other Papers

No structure scheme yet for this family

Structures in Asp2 family (2)

Genes Proteins in Asp2 family (304)

Fragments of genes in Asp2 family (6)

No Substrate

No Inhibitor

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

Acknowledgements and disclaimer