Family

Go to basket

Tree Display

AceDB Schema

XML Display

Feedback

Family Report for: Carbon-carbon_bond_hydrolase


Carbon-carbon_bond_hydrolase



Relationship
Block X
Parent Family : Epoxide-hydrolase_like


Comments

2-hydroxymuconic semialdehyde hydrolase PIRSF037174. Members of this family are 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase, or HOPD hydrolase, the BphD protein of biphenyl degradation. BphD acts on the product of ring meta-cleavage by BphC. Many species carrying bphC and bphD are capable of degrading polychlorinated biphenyls as well as biphenyl itself (environmental pollutants: BP/PCB). 2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6-oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid. The purified enzyme is a dimeric protein requiring no cofactors for catalytic activity



Database
Sequences
Interpro : IPR000073 (Alpha/beta hydrolase fold-1), IPR023791 (2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase), IPR017727 (2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase, BphD)
Pdoc :
PFam : PF12697 (Abhydrolase_6)
Prints :
Prosite :
EC at KEGG : 3.7.1.8
EC at EXPASY : 3.7.1.8
Peptide in Fasta
Nucleotide in Fasta
Alignment with Multalin : Text only/graphic display
Seed alignment with MAFFT : No colour/coloured with Mview
Alignment with MAFFT : No colour/coloured with Mview
Dendrogram : Graphical display, obtained with the dnd file produced by Clustalw
HMM profile : HMM profile





No Image


If the number of entries is too large in this family (>4000) or the page is too slow follow this link






Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page
webmaster

Acknowledgements and disclaimer