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Family Report for: Carboxymethylbutenolide_lactonase

Carboxymethylbutenolide_lactonase



Relationship
Block X
Parent Family : Abhydrolase_6

Comment
In some instance 3-oxoadipate enol-lactonase is fused to 4-carboxymucolactone- decarboxylase, which acts on the same pathway but this enzyme belongs to CMD IPR003779 PF02627 and is not related to alpha/beta hydrolase see Eulberg et al. 1998, see Schlomann et al. 1994 fo a review on the pathway. For bacterial enzymes, this family corresponds to family V.2 of the classification of Arpigny and Jaeger 1999

Database
Sequences
Interpro
|
IPR000073 (Alpha/beta hydrolase fold-1), IPR026968 (3-oxoadipate enol-lactonase 1/2)
PIRSF
|
Pdoc
|
PFam
|
PF12697 (Abhydrolase_6)
Prints
|
Prosite
|
EC at KEGG
|
EC at EXPASY
|


Peptide in
|Fasta
Nucleotide in
|Fasta
Alignment with Multalin
|Text only/graphic display
Seed alignment with MAFFT
|No colour/coloured with Mview
Alignment with MAFFT
|No colour/coloured with Mview
Dendrogram
|Graphical display, obtained with the dnd file produced by Clustalw

References
3 more
    Title: A product analog bound form of 3-oxoadipate-enol-lactonase (PcaD) reveals a multifunctional role for the divergent cap domain
    Bains J, Kaufman L, Farnell B, Boulanger MJ
    Ref: Journal of Molecular Biology, 406:649, 2011 : PubMed

            

    Title: Bacterial lipolytic enzymes: classification and properties
    Arpigny JL, Jaeger KE
    Ref: Biochemical Journal, 343:177, 1999 : PubMed

            

    Title: Characterization of a protocatechuate catabolic gene cluster from Rhodococcus opacus 1CP: evidence for a merged enzyme with 4-carboxymuconolactone-decarboxylating and 3-oxoadipate enol-lactone-hydrolyzing activity
    Eulberg D, Lakner S, Golovleva LA, Schlomann M
    Ref: Journal of Bacteriology, 180:1072, 1998 : PubMed

            

Other Papers


No structure scheme yet for this family

Structures in Carboxymethylbutenolide_lactonase family (2)

Genes Proteins in Carboxymethylbutenolide_lactonase family (725)

Fragments of genes in Carboxymethylbutenolide_lactonase family (1)

Substrates of some enzymes in the Carboxymethylbutenolide_lactonase family (2)

Inhibitors of some enzymes in the Carboxymethylbutenolide_lactonase family (1)



Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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