Duf_726
Comment
A lipase like protein: yeast-yfd4 Mil1(Yfl034w) specifically binds Apm2, one of the adaptor protein of (AP) complexes responsible for binding clathrin, cargo-sorting motifs, accessory factors, and membrane lipids. The paper by Whitfield et al. is the first description of a function for a member of the Duf_726 family. The same protein had been shown to interact with the ribosomal phosphoprotein P0 Aruna et al.. yeast-yfd4 has a conserved catalytic triad. Male-sterile rice mutant oslddt1 (leaked and delayed degraded tapetum 1). oslddt1 plants show complete pollen abortion resulting from delayed degradation of the tapetum and blocked formation of Ubisch bodies and pollen walls. Wax and cutin contents in mature oslddt1 anthers are drastically reduced indicating that orysj-q10ss2 OsLDDT1 OsLDDT1 is involved in fatty acid synthesis and affects formation of the anther epidermis ( Sun et al. 2023) Database
Interpro : IPR007941 Protein of unknown function DUF726
PIRSF : No PIRSF
Pdoc : No Pdoc
Pfam : PF05277 DUF726
Prints : No Print
EC Number : No EC Number
References (4)
| Title : OsLDDT1, encoding a transmembrane structural DUF726 family protein, is essential for tapetum degradation and pollen formation in rice - Sun_2023_Plant.Sci__111596 |
| Author(s) : Sun Z , Liu K , Chen C , Chen D , Peng Z , Zhou R , Liu L , He D , Duan W , Chen H , Huang C , Ruan Z , Zhang Y , Cao L , Zhan X , Cheng S , Sun L |
| Ref : Plant Sci , :111596 , 2023 |
| Abstract : Sun_2023_Plant.Sci__111596 |
| ESTHER : Sun_2023_Plant.Sci__111596 |
| PubMedSearch : Sun_2023_Plant.Sci__111596 |
| PubMedID: 36657664 |
| Gene_locus related to this paper: orysj-q10ss2 |
| Title : The alternate AP-1 adaptor subunit Apm2 interacts with the Mil1 regulatory protein and confers differential cargo sorting - Whitfield_2016_Mol.Biol.Cell_27_588 |
| Author(s) : Whitfield ST , Burston HE , Bean BD , Raghuram N , Maldonado-Baez L , Davey M , Wendland B , Conibear E |
| Ref : Mol Biology of the cell , 27 :588 , 2016 |
| Abstract : Whitfield_2016_Mol.Biol.Cell_27_588 |
| ESTHER : Whitfield_2016_Mol.Biol.Cell_27_588 |
| PubMedSearch : Whitfield_2016_Mol.Biol.Cell_27_588 |
| PubMedID: 26658609 |
| Gene_locus related to this paper: yeast-yfd4 |
| Title : Identification of a hypothetical membrane protein interactor of ribosomal phosphoprotein P0 - Aruna_2004_J.Biosci_29_33 |
| Author(s) : Aruna K , Chakraborty T , Nambeesan S , Mannan AB , Sehgal A , Bhalchandara SR , Sharma S |
| Ref : J Biosci , 29 :33 , 2004 |
| Abstract : Aruna_2004_J.Biosci_29_33 |
| ESTHER : Aruna_2004_J.Biosci_29_33 |
| PubMedSearch : Aruna_2004_J.Biosci_29_33 |
| PubMedID: 15286401 |
| Gene_locus related to this paper: yeast-yfd4 |
| Title : Synergistic computational and experimental proteomics approaches for more accurate detection of active serine hydrolases in yeast - Baxter_2004_Mol.Cell.Proteomics_3_209 |
| Author(s) : Baxter SM , Rosenblum JS , Knutson S , Nelson MR , Montimurro JS , Di Gennaro JA , Speir JA , Burbaum JJ , Fetrow JS |
| Ref : Mol Cell Proteomics , 3 :209 , 2004 |
| Abstract : Baxter_2004_Mol.Cell.Proteomics_3_209 |
| ESTHER : Baxter_2004_Mol.Cell.Proteomics_3_209 |
| PubMedSearch : Baxter_2004_Mol.Cell.Proteomics_3_209 |
| PubMedID: 14645503 |
| Gene_locus related to this paper: yeast-FSH1 , yeast-FSH2 , yeast-FSH3 , yeast-mgll , yeast-ppme1 , yeast-YDR428C , yeast-yfd4 , yeast-YLR118c |
No structure scheme yet for this family
Genes Proteins in Duf_726 family (139)
Fragments of genes in Duf_726 family (13)
No fragment of genesNo substrate
No Inhibitor