GTSAGmotif

Relationship

Family: GTSAGmotif

Block: H

Parent Family: No family

Comment

Sequences of lipases from metagenomic library were grouped in a new subset of Alphabeta hydrolase fold-3 (Arpigny_Jaeger Family_IV). Most sequences have a G(TDC)SA(G)G motif encompassing the active site serine.

Database

Interpro : IPR013094 Alpha\/beta hydrolase fold-3

PIRSF : No PIRSF

Pdoc : No Pdoc

Pfam : PF07859 Abhydrolase_3

Prints : No Print

EC Number : No EC Number

Sequences

Peptide in Fasta
Nucleotide in Fasta
Alignment with Multalin Text only
Seed alignment with MAFFT No colour
Alignment with MAFFT No colour
Dendrogram The dnd file

References (5)

Title : Crystal structure of PMGL2 esterase from the hormone-sensitive lipase family with GCSAG motif around the catalytic serine - Boyko_2020_PLoS.One_15_e0226838
Author(s) : Boyko KM , Kryukova MV , Petrovskaya LE , Nikolaeva AY , Korzhenevsky DA , Novototskaya-Vlasova KA , Rivkina EM , Dolgikh DA , Kirpichnikov MP , Popov VO
Ref : PLoS ONE , 15 :e0226838 , 2020
Abstract : Boyko_2020_PLoS.One_15_e0226838
ESTHER : Boyko_2020_PLoS.One_15_e0226838
PubMedSearch : Boyko_2020_PLoS.One_15_e0226838
PubMedID: 31990908
Gene_locus related to this paper: 9bact-a0a142j6i6

Title : Expression and characterization of a new esterase with GCSAG motif from a permafrost metagenomic library - Petrovskaya_2016_FEMS.Microbiol.Ecol_92_
Author(s) : Petrovskaya LE , Novototskaya-Vlasova KA , Spirina EV , Durdenko EV , Lomakina GY , Zavialova MG , Nikolaev EN , Rivkina EM
Ref : FEMS Microbiol Ecol , 92 : , 2016
Abstract : Petrovskaya_2016_FEMS.Microbiol.Ecol_92_
ESTHER : Petrovskaya_2016_FEMS.Microbiol.Ecol_92_
PubMedSearch : Petrovskaya_2016_FEMS.Microbiol.Ecol_92_
PubMedID: 26929439
Gene_locus related to this paper: 9bact-a0a142j6i6

Title : Pressure adaptation is linked to thermal adaptation in salt-saturated marine habitats - Alcaide_2015_Environ.Microbiol_17_332
Author(s) : Alcaide M , Stogios PJ , Lafraya A , Tchigvintsev A , Flick R , Bargiela R , Chernikova TN , Reva ON , Hai T , Leggewie CC , Katzke N , La Cono V , Matesanz R , Jebbar M , Jaeger KE , Yakimov MM , Yakunin AF , Golyshin PN , Golyshina OV , Savchenko A , Ferrer M
Ref : Environ Microbiol , 17 :332 , 2015
Abstract : Alcaide_2015_Environ.Microbiol_17_332
ESTHER : Alcaide_2015_Environ.Microbiol_17_332
PubMedSearch : Alcaide_2015_Environ.Microbiol_17_332
PubMedID: 25330254
Gene_locus related to this paper: 9alte-MGS-MT1 , 9bact-MGS-M1 , 9bact-MGS-M2 , 9bact-a0a0b5kns5

Title : Structural Basis for Dimerization and Catalysis of a Novel Esterase from the GTSAG Motif Subfamily of the Bacterial Hormone-sensitive Lipase Family - Li_2014_J.Biol.Chem_289_19031
Author(s) : Li PY , Ji P , Li CY , Zhang Y , Wang GL , Zhang XY , Xie BB , Qin QL , Chen XL , Zhou BC , Zhang YZ
Ref : Journal of Biological Chemistry , 289 :19031 , 2014
Abstract : Li_2014_J.Biol.Chem_289_19031
ESTHER : Li_2014_J.Biol.Chem_289_19031
PubMedSearch : Li_2014_J.Biol.Chem_289_19031
PubMedID: 24867954
Gene_locus related to this paper: 9bact-E25

Title : Identification of a new subfamily of salt-tolerant esterases from a metagenomic library of tidal flat sediment - Jeon_2012_Appl.Microbiol.Biotechnol_93_623
Author(s) : Jeon JH , Lee HS , Kim JT , Kim SJ , Choi SH , Kang SG , Lee JH
Ref : Applied Microbiology & Biotechnology , 93 :623 , 2012
Abstract : Jeon_2012_Appl.Microbiol.Biotechnol_93_623
ESTHER : Jeon_2012_Appl.Microbiol.Biotechnol_93_623
PubMedSearch : Jeon_2012_Appl.Microbiol.Biotechnol_93_623
PubMedID: 21720822
Gene_locus related to this paper: 9bact-E40 , 9bact-E25 , 9bact-d8v1j5 , 9bact-d8v1j4 , 9bact-d8v1j3

Structures (5)

Genes Proteins in GTSAGmotif family (112)

Fragments of genes in GTSAGmotif family (9)

Structures in GTSAGmotif family (5)

Substrates in GTSAGmotif family (6)

Inhibitors in GTSAGmotif family (1)