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Family Report for: HNLyase_Bact


Block X
Parent Family : Abhydrolase_6

This family is close to the Hydroxynitrile_lyase of Plants although not fully characterized yet. The first enzyme studied by Reiter et al. was able to hydrolyze a variety of esterase substrates of low to medium carbonic acid chain length, but no triglycerides were hydrolyzed. Despite the high sequence homology, no hydroxynitrile lyase activity could be recognized. Plant Hydroxynitrile_lyase are grouped in another family. Hydroxynitrile_lyase but are very closely related). Proteins in this entry also include pyrethroids pesticides hydrolase PytH from Sphingobium wenxiniae

IPR045889 (Methylesterase/Alpha-hydroxynitrile lyase)
no EC number

Peptide in
Nucleotide in
Alignment with Multalin
|Text only/graphic display
Seed alignment with MAFFT
|No colour/coloured with Mview
Alignment with MAFFT
|No colour/coloured with Mview
|Graphical display, obtained with the dnd file produced by Clustalw

1 more
    Title: Structure and Catalytic Mechanism of a Pyrethroid Carboxylesterase PytH from Sphingobium faniae JZ-2
    Xu D, Gao Y, Sun B, Ran T, Zeng L, He J, Wang W
    Ref: Applied Environmental Microbiology, :, 2020 : PubMed


    Title: Cloning of a novel pyrethroid-hydrolyzing carboxylesterase gene from Sphingobium sp. strain JZ-1 and characterization of the gene product
    Wang BZ, Guo P, Hang BJ, Li L, He J, Li SP
    Ref: Applied Environmental Microbiology, 75:5496, 2009 : PubMed


    Title: Cloning and characterization of EstC from Burkholderia gladioli, a novel-type esterase related to plant enzymes
    Reiter B, Glieder A, Talker D, Schwab H
    Ref: Applied Microbiology & Biotechnology, 54:778, 2000 : PubMed


Other Papers

No structure scheme yet for this family

Structures in HNLyase_Bact family (7)

Genes Proteins in HNLyase_Bact family (204)

Fragments of genes in HNLyase_Bact family (6)

Substrates of some enzymes in the HNLyase_Bact family (13)

Inhibitors of some enzymes in the HNLyase_Bact family (1)

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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