Lysin_B_C_ter
Relationship
Comment
Lysin B (LysB), a novel mycolylarabinogalactan esterase from mycobacteriophage, that cleaves the mycolylarabinogalactan bond to release free mycolic acids. The D29 LysB structure shows an alpha/beta hydrolase organization with a catalytic triad common to cutinases, but which contains an additional four-helix domain implicated in the binding of lipid substrates. This superfamily entry represents the linker domain of the mycobacteriophage Lysin B. The linker domain is composed of four alpha-helices connecting the C-terminal alpha-helix back to the side of the central beta-sheet.Family close to cutinasesDatabase
Interpro : IPR041855 Lysin B, C-terminal linker domain Lysin_B_C_ter
PIRSF : No PIRSF
Pdoc : No Pdoc
Pfam : No Pfam
Prints : No Print
EC Number : No EC Number
References (2)
| Title : Comparative Structural Analysis of Different Mycobacteriophage-Derived Mycolylarabinogalactan Esterases (Lysin B) - Korany_2019_Biomolecules_10_ |
| Author(s) : Korany AH , Abouhmad A , Bakeer W , Essam T , Amin MA , Hatti-Kaul R , Dishisha T |
| Ref : Biomolecules , 10 : , 2019 |
| Abstract : Korany_2019_Biomolecules_10_ |
| ESTHER : Korany_2019_Biomolecules_10_ |
| PubMedSearch : Korany_2019_Biomolecules_10_ |
| PubMedID: 31892223 |
| Title : Mycobacteriophage Lysin B is a novel mycolylarabinogalactan esterase - Payne_2009_Mol.Microbiol_73_367 |
| Author(s) : Payne K , Sun Q , Sacchettini J , Hatfull GF |
| Ref : Molecular Microbiology , 73 :367 , 2009 |
| Abstract : Payne_2009_Mol.Microbiol_73_367 |
| ESTHER : Payne_2009_Mol.Microbiol_73_367 |
| PubMedSearch : Payne_2009_Mol.Microbiol_73_367 |
| PubMedID: 19555454 |
| Gene_locus related to this paper: bpmd2-vg12 |
Structures (1)
Genes Proteins in Lysin_B_C_ter family (28)
No fragment of genes
Structures in Lysin_B_C_ter family (1)No substrate
No Inhibitor