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Family Report for: PAF_acetylhydro-like

PAF_acetylhydro-like



Relationship
Block X


Comment
Platelet-activating factor acetylhydrolase (PAF-AH) is a subfamily of phospholipase A2, and is involved in regulation of inflammation through the inactivation of platelet-activating factor and polar phospholipids
1 Disease(s)


Database
Sequences
Interpro
|
IPR005065 (Platelet-activating factor acetylhydrolase-like)
PIRSF
|
Pdoc
|
PFam
|
PF03403 (PAF-AH_p_II)
Prints
|
Prosite
|
no EC number



Peptide in
|Fasta
Nucleotide in
|Fasta
Alignment with Multalin
|Text only/graphic display
Seed alignment with MAFFT
|No colour/coloured with Mview
Alignment with MAFFT
|No colour/coloured with Mview
Dendrogram
|Graphical display, obtained with the dnd file produced by Clustalw

References
    Title: Crystal structure of human plasma platelet-activating factor acetylhydrolase: structural implication to lipoprotein binding and catalysis
    Samanta U, Bahnson BJ
    Ref: Journal of Biological Chemistry, 283:31617, 2008 : PubMed

            

    Title: The structure and function of platelet-activating factor acetylhydrolases
    Derewenda ZS, Derewenda U
    Ref: Cell Mol Life Sciences, 54:446, 1998 : PubMed

            

    Title: Structure of a microbial homologue of mammalian platelet-activating factor acetylhydrolases: Streptomyces exfoliatus lipase at 1.9 A resolution
    Wei Y, Swenson L, Castro C, Derewenda U, Minor W, Arai H, Aoki J, Inoue K, Servin-Gonzalez L, Derewenda ZS
    Ref: Structure, 6:511, 1998 : PubMed

            

Other Papers


Structure scheme for PAF_acetylhydro-like

Structures in PAF_acetylhydro-like family (35)

Genes Proteins in PAF_acetylhydro-like family (453)

Fragments of genes in PAF_acetylhydro-like family (7)

No Substrate

No Inhibitor



Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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