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PMH_Peptidase_S9

Relationship

Family: PMH_Peptidase_S9

Block: X

Parent Family: Peptidase_S9

Comment

Puromycine hydrolase (and also pQQM from Pseudomonas, C. Elegans dp4). Some Streptomyces strains produce Puromycin (PM classified into a family of nucleoside antibiotics) and express a PM-inactivating enzyme as a self-resistance determinant which is homologous to Peptidase S9

Database

Interpro : IPR011042 6-blade_b-propeller_TolB-like , IPR001375 Peptidase_S9

PIRSF : No PIRSF

Pdoc : No Pdoc

Pfam : PF00326 Peptidase_S9

Prints : No Print

EC Number : No EC Number

Sequences

Peptide in Fasta
Nucleotide in Fasta
Alignment with Multalin Text only
Seed alignment with MAFFT No colour
Alignment with MAFFT No colour
Dendrogram The dnd file

References (3)

Title : Mycobacterium tuberculosis puromycin hydrolase displays a prolyl oligopeptidase fold and an acyl aminopeptidase activity - Zhao_2021_Proteins__
Author(s) : Zhao Y , Feng Q , Zhou X , Zhang Y , Lukman M , Jiang J , Ruiz-Carrillo D
Ref : Proteins , : , 2021
Abstract : Zhao_2021_Proteins__
ESTHER : Zhao_2021_Proteins__
PubMedSearch : Zhao_2021_Proteins__
PubMedID: 33426726
Gene_locus related to this paper: myctu-CNE19725

Title : Structural evidence that puromycin hydrolase is a new type of aminopeptidase with a prolyl oligopeptidase family fold -
Author(s) : Matoba Y , Nakayama A , Oda K , Noda M , Kumagai T , Nishimura M , Sugiyama M
Ref : Proteins , 79 :2999 , 2011
PubMedID: 21905123
Gene_locus related to this paper: strmo-q2hxd9

Title : Molecular cloning and characterization of gene encoding novel puromycin-inactivating enzyme from blasticidin S-producing Streptomyces morookaensis - Nishimura_2006_J.Biosci.Bioeng_101_63
Author(s) : Nishimura M , Ikeda K , Sugiyama M
Ref : J Biosci Bioeng , 101 :63 , 2006
Abstract : Nishimura_2006_J.Biosci.Bioeng_101_63
ESTHER : Nishimura_2006_J.Biosci.Bioeng_101_63
PubMedSearch : Nishimura_2006_J.Biosci.Bioeng_101_63
PubMedID: 16503293
Gene_locus related to this paper: strmo-q2hxd9

Structures (4)

Genes Proteins in PMH_Peptidase_S9 family (92)

Fragments of genes in PMH_Peptidase_S9 family (7)

Structures in PMH_Peptidase_S9 family (4)

Substrates in PMH_Peptidase_S9 family (3)

No Inhibitor