Family

Go to basket

Tree Display

AceDB Schema

XML Display

Feedback

Family Report for: PhoPQ_related

PhoPQ_related



Relationship
Block X
Comment
IPR009199 PIRSF014728 PhoPQ-activated pathogenicity-related protein, PqaA type. Proteins in this entry are believed to play a role in virulence/pathogenicity in Salmonella. Salmonella typhi PqaA has been shown to be activated by PhoP/Q two-component regulatory system, which regulates many virulence genes Baker et al 1997. It has been also shown to confer resistance to antimicrobial peptides (melittin). Autocrine proliferation repressor protein A (AprA, CfaD) is a protein secreted by Dictyostelium discoideum cells. AprA has DPPIV-like protease activity

Database
Sequences
Interpro
|
IPR009199 (PhoPQ-activated pathogenicity-related protein, PqaA type)
PIRSF
|
Pdoc
|
PFam
|
PF10142 (PhoPQ_related)
Prints
|
Prosite
|
no EC number



Peptide in
|Fasta
Nucleotide in
|Fasta
Alignment with Multalin
|Text only/graphic display
Seed alignment with MAFFT
|No colour/coloured with Mview
Alignment with MAFFT
|No colour/coloured with Mview
Dendrogram
|Graphical display, obtained with the dnd file produced by Clustalw

References
3 more
    Title: Functional similarities between the dictyostelium protein AprA and the human protein dipeptidyl-peptidase IV
    Herlihy SE, Tang Y, Phillips JE, Gomer RH
    Ref: Protein Science, 26:578, 2017 : PubMed

            

    Title: Rcs and PhoPQ regulatory overlap in the control of Salmonella enterica virulence.
    Garcia-Calderon CB, Casadesus J, Ramos-Morales F
    Ref: Journal of Bacteriology, 189:6635, 2007 : PubMed

            

    Title: PhoP/Q regulated genes in Salmonella typhi identification of melittin sensitive mutants
    Baker SJ, Daniels C, Morona R
    Ref: Microb Pathog, 22:165, 1997 : PubMed

            

Other Papers


No structure scheme yet for this family

No Structure yet in this family

Genes Proteins in PhoPQ_related family (63)

Fragments of genes in PhoPQ_related family (3)

No Substrate

No Inhibitor



Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page
webmaster

Acknowledgements and disclaimer