Gene_Locus Report

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Gene_locus Report for: 9acto-q1psf5

Streptomyces tsusimaensis discrete type II thioesterase

Relationship
Family|Thioesterase
Block| X
Position in NCBI Life Tree|Streptomyces tsusimaensis
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Bacteria: N E > Terrabacteria group: N E > Actinobacteria [phylum]: N E > Actinobacteria [class]: N E > Streptomycetales: N E > Streptomycetaceae: N E > Streptomyces: N E > Streptomyces tsusimaensis: N E


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
1 Genbank : DQ174261
1 UniProt : Q1PSF5
1 UniProt : Q1PSF5
1 Interpro : Q1PSF5
1 Prodom : Q1PSF5
1 Pfam : Q1PSF5
1 PIRSF : Q1PSF5
1 SUPERFAM : Q1PSF5
Sequence
Graphical view for this peptide sequence: 9acto-q1psf5
Colored MSA for Thioesterase (raw)
MKLLCLPHAGGTASRYHRWTSLVPPYIDIVPLELDGRGDRMSQGFYASFA
EALDDLTRRAVTALEPGDSYAIFGHSMGAYLALELERRLESLGLRAERLF
LSGRGTPDYRHVLSRPVRELSDQELIAGLDVYGGLPDAIARHELMRTLFL
PIIRADFHLLEDGARSIDEHVPVRSPLTILNGKDDMSAQQAPPGVWEALS
ASGVEFRSYAGGHFFVDDNLQSIIELIVEKTKRGLEKDGVSFQG
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MKLLCLPHAGGTASRYHRWTSLVPPYIDIVPLELDGRGDRMSQGFYASFA
EALDDLTRRAVTALEPGDSYAIFGHSMGAYLALELERRLESLGLRAERLF
LSGRGTPDYRHVLSRPVRELSDQELIAGLDVYGGLPDAIARHELMRTLFL
PIIRADFHLLEDGARSIDEHVPVRSPLTILNGKDDMSAQQAPPGVWEALS
ASGVEFRSYAGGHFFVDDNLQSIIELIVEKTKRGLEKDGVSFQG


Reference
    Title: Deciphering the biosynthetic codes for the potent anti-SARS-CoV cyclodepsipeptide valinomycin in Streptomyces tsusimaensis ATCC 15141
    Cheng YQ
    Ref: Chembiochem, 7:471, 2006 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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