(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) > cellular organisms: NE > Bacteria: NE > FCB group: NE > Bacteroidetes/Chlorobi group: NE > Bacteroidetes: NE > Bacteroidia: NE > Bacteroidales: NE > Bacteroidaceae: NE > Bacteroides: NE > Bacteroides sp. 4_3_47FAA: NE
Warning: This entry is a compilation of different species or line or strain with more than 90% amino acid identity. You can retrieve all strain data
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) Bacteroides vulgatus ATCC 8482: N, E.
Bacteroides vulgatus str. 3975 RP4: N, E.
Bacteroides vulgatus str. 3775 SL(B) 10 (iv): N, E.
Bacteroides vulgatus: N, E.
Bacteroides vulgatus PC510: N, E.
Bacteroides vulgatus dnLKV7: N, E.
Bacteroides vulgatus CL09T03C04: N, E.
Bacteroides sp. 3_1_40A: N, E.
Bacteroides vulgatus CAG:6: N, E.
LegendThis sequence has been compared to family alignement (MSA) red => minority aminoacid blue => majority aminoacid color intensity => conservation rate title => sequence position(MSA position)aminoacid rate Catalytic site Catalytic site in the MSA MKNTVICLLLFGISLTASAQEKVETVSMRYETQNDMPLFYQKMKENLTYP MAWGNSAIRNFEKWREEARKTLLDCMLPAPPATAFDKEVIDTEQRNGYRA EKILFSVSEYSRVPAYLLVPDGNGPFPAVLLLHDHGAHFSIGKEKMVRPF GVEASVLADADDWAEKCYDKQYVGDYLASHGYVVLAVDALFWGERGRKEG VRYDSQQALAANMLQMGMSWGALIAWDDIRSAEFLASLPMVHKEKIGTMG FSMGAHRAWMVSAATDVVKAGAAVCWMNTTDSLMTLTNNQNKGGSAYSMI IPGIRNWMDYPHVASIACPKPMLFINGLRDKLFPVKGVESAFSTMQDVWK SQSVENLLTTKFYDLPHFCSKEIQDDILEFFNQNLK
The adult human intestine contains trillions of bacteria, representing hundreds of species and thousands of subspecies. Little is known about the selective pressures that have shaped and are shaping this community's component species, which are dominated by members of the Bacteroidetes and Firmicutes divisions. To examine how the intestinal environment affects microbial genome evolution, we have sequenced the genomes of two members of the normal distal human gut microbiota, Bacteroides vulgatus and Bacteroides distasonis, and by comparison with the few other sequenced gut and non-gut Bacteroidetes, analyzed their niche and habitat adaptations. The results show that lateral gene transfer, mobile elements, and gene amplification have played important roles in affecting the ability of gut-dwelling Bacteroidetes to vary their cell surface, sense their environment, and harvest nutrient resources present in the distal intestine. Our findings show that these processes have been a driving force in the adaptation of Bacteroidetes to the distal gut environment, and emphasize the importance of considering the evolution of humans from an additional perspective, namely the evolution of our microbiomes.
