Gene_Locus Report

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Gene_locus Report for: 9neop-ACHE1

Chilo suppressalis (striped riceborer) acetylcholinesterase 1 (Ace1) mRNA, complete cds

Comment
Asiatic rice borer moth


Relationship
Family|ACHE
Block| C
Position in NCBI Life Tree|Chilo suppressalis
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Protostomia: N E > Ecdysozoa: N E > Panarthropoda: N E > Arthropoda: N E > Mandibulata: N E > Pancrustacea: N E > Hexapoda: N E > Insecta: N E > Dicondylia: N E > Pterygota: N E > Neoptera: N E > Holometabola: N E > Amphiesmenoptera: N E > Lepidoptera: N E > Glossata: N E > Neolepidoptera: N E > Heteroneura: N E > Ditrysia: N E > Obtectomera: N E > Pyraloidea: N E > Crambidae: N E > Crambinae: N E > Chilo: N E > Chilo suppressalis: N E


Molecular evidence
Database
5 mutations: Table (e.g. : A314S, E101D, F402V ... more)
No structure
No kinetic





No Substrate
No inhibitor
2 Genbank : EF453724, ABO38111
1 UniProt : A5HBN8
3 UniProt : A5HBN8, A0A0B4RY90, A0A0G3VFZ6
3 Interpro : A5HBN8, A0A0B4RY90, A0A0G3VFZ6
3 Prodom : A5HBN8, A0A0B4RY90, A0A0G3VFZ6
3 Pfam : A5HBN8, A0A0B4RY90, A0A0G3VFZ6
3 PIRSF : A5HBN8, A0A0B4RY90, A0A0G3VFZ6
3 SUPERFAM : A5HBN8, A0A0B4RY90, A0A0G3VFZ6
Sequence
Graphical view for this peptide sequence: 9neop-ACHE1
Colored MSA for ACHE (raw)
MRVVLAALTALAARALAGPHEHRARHHAPDHPLHFPAPANPAQPYRGHGE
AARYNPELDTILPRVEDHETSSKRAKLDDAETSSKRDDDRFYSNHERIDD
EGFLADEPQPGPEDDDPLIVRTRKGRVRGITLTAATGKKVDAWFGIPYAQ
KPIGDLRFRHPRPAESWGEEILNTTTLPHPCVQIIDTVFGDFPGAMMWNP
NTDMQEDCLYINIVSPRPRPKNAAVMLWVFGGGFYSGTATLDVYDPKIMV
SEEKIVYVSMQYRVASLGFLFFDTPDVPGNAGMFDQLMALQWVKDNIAYF
GGNPHNVTLFGESAGAVSVSLHLLSPLSRNLFSQAIMQSGAATAPWAIIS
REESILRGTRLAEAVHCPHSLKDMGPMIECLRKKSADELVNNEWGTLGIC
EFPFVPIIDGSFLDEMPIRSLAHQNFKKTNILMGSNTEEGYYFILYYLTE
LFPKEENVGITREQYLQAVRELNPYVSDVGRQAIVFEYTDWLNPEDPVRN
RNALDKMVGDYHFTCGVNEFAHRYAETGNNVYTYYYKHRSKNNPWPSWTG
VMHADEINYVFGEPLNPGKNYSPEEVEFSKRIMRYWANFARSGNPSLNPN
GDMTKVHWPVHTAFGGEYLSLAVNSSAVGHGLKVKQCAFWQKYLPQLMAA
TTKPEPIQNCTSNSGTRHYYGVTSLSLVTVFGFLQPTILKYIII
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MRVVLAALTALAARALAGPHEHRARHHAPDHPLHFPAPANPAQPYRGHGE
AARYNPELDTILPRVEDHETSSKRAKLDDAETSSKRDDDRFYSNHERIDD
EGFLADEPQPGPEDDDPLIVRTRKGRVRGITLTAATGKKVDAWFGIPYAQ
KPIGDLRFRHPRPAESWGEEILNTTTLPHPCVQIIDTVFGDFPGAMMWNP
NTDMQEDCLYINIVSPRPRPKNAAVMLWVFGGGFYSGTATLDVYDPKIMV
SEEKIVYVSMQYRVASLGFLFFDTPDVPGNAGMFDQLMALQWVKDNIAYF
GGNPHNVTLFGESAGAVSVSLHLLSPLSRNLFSQAIMQSGAATAPWAIIS
REESILRGTRLAEAVHCPHSLKDMGPMIECLRKKSADELVNNEWGTLGIC
EFPFVPIIDGSFLDEMPIRSLAHQNFKKTNILMGSNTEEGYYFILYYLTE
LFPKEENVGITREQYLQAVRELNPYVSDVGRQAIVFEYTDWLNPEDPVRN
RNALDKMVGDYHFTCGVNEFAHRYAETGNNVYTYYYKHRSKNNPWPSWTG
VMHADEINYVFGEPLNPGKNYSPEEVEFSKRIMRYWANFARSGNPSLNPN
GDMTKVHWPVHTAFGGEYLSLAVNSSAVGHGLKVKQCAFWQKYLPQLMAA
TTKPEPIQNCTSNSGTRHYYGVTSLSLVTVFGFLQPTILKYIII


Reference
    Title: Mutation in acetylcholinesterase1 associated with triazophos resistance in rice stem borer, Chilo suppressalis (Lepidoptera: Pyralidae)
    Jiang X, Qu M, Denholm I, Fang J, Jiang W, Han Z
    Ref: Biochemical & Biophysical Research Communications, 378:269, 2009 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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