Aedes aegypti (Yellowfever mosquito) alpha-esterase CCEae6a
Bioassays on Ae. aegypti larvae from Thailand detected temephos resistance ratios ranging from 3.5 fold in Chiang Mai to nearly 10 fold in Nakhon Sawan (NS) province. CCEae3a, was upregulated more than 60 fold in the NS population compared to the susceptible population. A similar amplification occurs in other major arbovirus vector in the Asian Tiger Mosquito Aedes albopictus. The few mutaions found originally in the amplified allele do not seem to participate in resistance CCEae6a also amplified
MFHTIEQSLK MSAANRINVK VHQGTVSGVR EKLPNGNESF AFRGIPYAKP PVGELRFKAP QPLDKFQYPI LDCSVERDVC FSRNMFTQEI EGSEDCLYLN VYSPKIGSDD KALPVMVFIH GGAFMFGSGN SDCYSPEYLV QEDVVAVTLN YRLGTLGFTY LPSQGIEGNS GLKDQLMALK WIKQNIAKFG GDPNNVTMFG ESAGAASVHL HLLSPNSRQY FHKAICQSGC SIMEWVMQRD PEYKARTLAK LIGCKGQSDE EVYETLMTSS TADVVGRMVS VLTDDEKIRG LPMPFKPVVE SESATDAIVT KAPIDVMKTP NAIPNIPVMM GVNNREGTIM LLDGIKKLEL YENDMARLIP RTVNVNPGTV ASNELGEEIK KFYFGNQPIT TKMLPQLADL MSDYHFSILA NVCCELHSRY QHQSPLYYYN FSFDGMLNMY KRLLNLKVPG ACHADELSYQ FLFRMAPVEV EPESPEARVR YYMCRMWTNF AKYGNPTPPE DSTLPYRWDP VGKIAAESKE DFQLNCLDIT EEPKMITNPD KHRMDFWRSV YRRFNEGMLK VKL
| Title : Carboxylesterase gene amplifications associated with insecticide resistance in Aedes albopictus: Geographical distribution and evolutionary origin - Grigoraki_2017_PLoS.Negl.Trop.Dis_11_e0005533 |
| Author(s) : Grigoraki L , Pipini D , Labbe P , Chaskopoulou A , Weill M , Vontas J |
| Ref : PLoS Negl Trop Dis , 11 :e0005533 , 2017 |
| Abstract : Grigoraki_2017_PLoS.Negl.Trop.Dis_11_e0005533 |
| ESTHER : Grigoraki_2017_PLoS.Negl.Trop.Dis_11_e0005533 |
| PubMedSearch : Grigoraki_2017_PLoS.Negl.Trop.Dis_11_e0005533 |
| PubMedID: 28394886 |
| Gene_locus related to this paper: aedae-q17b28 , aedae-q17b31 |
| Title : Functional and immunohistochemical characterization of CCEae3a, a carboxylesterase associated with temephos resistance in the major arbovirus vectors Aedes aegypti and Ae. albopictus - Grigoraki_2016_Insect.Biochem.Mol.Biol_74_61 |
| Author(s) : Grigoraki L , Balabanidou V , Meristoudis C , Myridakis A , Ranson H , Swevers L , Vontas J |
| Ref : Insect Biochemistry & Molecular Biology , 74 :61 , 2016 |
| Abstract : Grigoraki_2016_Insect.Biochem.Mol.Biol_74_61 |
| ESTHER : Grigoraki_2016_Insect.Biochem.Mol.Biol_74_61 |
| PubMedSearch : Grigoraki_2016_Insect.Biochem.Mol.Biol_74_61 |
| PubMedID: 27180726 |
| Gene_locus related to this paper: aedae-q17b28 , aedae-q17b31 |
| Title : Transcriptome Profiling and Genetic Study Reveal Amplified Carboxylesterase Genes Implicated in Temephos Resistance, in the Asian Tiger Mosquito Aedes albopictus - Grigoraki_2015_PLoS.Negl.Trop.Dis_9_e0003771 |
| Author(s) : Grigoraki L , Lagnel J , Kioulos I , Kampouraki A , Morou E , Labbe P , Weill M , Vontas J |
| Ref : PLoS Negl Trop Dis , 9 :e0003771 , 2015 |
| Abstract : Grigoraki_2015_PLoS.Negl.Trop.Dis_9_e0003771 |
| ESTHER : Grigoraki_2015_PLoS.Negl.Trop.Dis_9_e0003771 |
| PubMedSearch : Grigoraki_2015_PLoS.Negl.Trop.Dis_9_e0003771 |
| PubMedID: 26000638 |
| Gene_locus related to this paper: aedae-q17b28 , aedae-q17b31 |
| Title : Identification of Carboxylesterase Genes Implicated in Temephos Resistance in the Dengue Vector Aedes aegypti - Poupardin_2014_PLoS.Negl.Trop.Dis_8_e2743 |
| Author(s) : Poupardin R , Srisukontarat W , Yunta C , Ranson H |
| Ref : PLoS Negl Trop Dis , 8 :e2743 , 2014 |
| Abstract : Poupardin_2014_PLoS.Negl.Trop.Dis_8_e2743 |
| ESTHER : Poupardin_2014_PLoS.Negl.Trop.Dis_8_e2743 |
| PubMedSearch : Poupardin_2014_PLoS.Negl.Trop.Dis_8_e2743 |
| PubMedID: 24651719 |
| Gene_locus related to this paper: aedae-q17b28 , aedae-q17b31 |