Aedes aegypti (Yellowfever mosquito) (Culex aegypti) alpha-esterase CCEae3a AAEL023844
Bioassays on Ae. aegypti larvae from Thailand detected temephos resistance ratios ranging from 3.5 fold in Chiang Mai to nearly 10 fold in Nakhon Sawan (NS) province. CCEae3a, was upregulated more than 60 fold in the NS population compared to the susceptible population. A similar amplification occurs in other major arbovirus vector in the Asian Tiger Mosquito Aedes albopictus. The few mutaions found originally in the amplified allele do not seem to participate in resistance
MSTLERVITQ LSAGKVQGCK SALPNGNSYC LYRGIPYAKP PVGELRFRPP VALERFEEEV LDCSYERSSC YAYMHFPPTV AVSEDCLYAN VYTPIDPTEI ERTIPLPVMV WIHGGGFIAG SGDAAIYGPR YIVQEGVIVV TFNYRLGPLG FLYFPEKGIY GNMGLKDQRF LLKWVQENIS KFGGDPDNVT IFGESAGGAS CHLQYLCESS RKYFHKAICQ SGVAVTVWTE QMDAVSKTRN LAKFVGCVAE SDDEIYETLM SAPADDLIAG SEQCVSDLDR SIYRIFAFSP VVEPKESEDP FITENYVDIL RNPNMTNIPL ILGLTSNEAI CFIQNLSVEL YANDAKLFVP PQLAVPEDRL LQVGEEVKRF YFENRTVSSE NLQFLLDFVS DCMFVIPVCV ASELHSRYQH SAPQYFYCFS FEGKSNHIKA MFQNDYQLEG AAHADELTYM FEASFFTTEE MDTDSQEYKI RKAMCRMWTN FAKCGNPTPD EDQLDILWQP VEKIDPDQEK YNIRALDLNE PSKMVDHPFE KRVNFWKRLF EKYGGNYLLH RALQ
Title : Aedes aegypti CCEae3A carboxylase expression confers carbamate, organophosphate and limited pyrethroid resistance in a model transgenic mosquito - Poulton_2024_PLoS.Negl.Trop.Dis_18_e0011595 |
Author(s) : Poulton BC , Colman F , Anthousi A , Sattelle DB , Lycett GJ |
Ref : PLoS Negl Trop Dis , 18 :e0011595 , 2024 |
Abstract : Poulton_2024_PLoS.Negl.Trop.Dis_18_e0011595 |
ESTHER : Poulton_2024_PLoS.Negl.Trop.Dis_18_e0011595 |
PubMedSearch : Poulton_2024_PLoS.Negl.Trop.Dis_18_e0011595 |
PubMedID: 38377131 |
Gene_locus related to this paper: aedae-q17b31 |
Title : A genomic amplification affecting a carboxylesterase gene cluster confers organophosphate resistance in the mosquito Aedes aegypti: From genomic characterization to high-throughput field detection - Cattel_2020_Evol.Appl__ |
Author(s) : Cattel J , Haberkorn C , Laporte F , Gaude T , Cumer T , Renaud J , Sutherland IW , Hertz JC , Bonneville JM , Arnaud V , Nous C , Fustec B , Boyer S , Marcombe S , David JP |
Ref : Evol Appl , : , 2020 |
Abstract : Cattel_2020_Evol.Appl__ |
ESTHER : Cattel_2020_Evol.Appl__ |
PubMedSearch : Cattel_2020_Evol.Appl__ |
PubMedID: |
Gene_locus related to this paper: aedae-q17b31 |
Title : Distribution of insecticide resistance and mechanisms involved in the arbovirus vector Aedes aegypti in Laos and implication for vector control - Marcombe_2019_PLoS.Negl.Trop.Dis_13_e0007852 |
Author(s) : Marcombe S , Fustec B , Cattel J , Chonephetsarath S , Thammavong P , Phommavanh N , David JP , Corbel V , Sutherland IW , Hertz JC , Brey PT |
Ref : PLoS Negl Trop Dis , 13 :e0007852 , 2019 |
Abstract : Marcombe_2019_PLoS.Negl.Trop.Dis_13_e0007852 |
ESTHER : Marcombe_2019_PLoS.Negl.Trop.Dis_13_e0007852 |
PubMedSearch : Marcombe_2019_PLoS.Negl.Trop.Dis_13_e0007852 |
PubMedID: 31830027 |
Gene_locus related to this paper: aedae-q17b31 |
Title : Carboxylesterase gene amplifications associated with insecticide resistance in Aedes albopictus: Geographical distribution and evolutionary origin - Grigoraki_2017_PLoS.Negl.Trop.Dis_11_e0005533 |
Author(s) : Grigoraki L , Pipini D , Labbe P , Chaskopoulou A , Weill M , Vontas J |
Ref : PLoS Negl Trop Dis , 11 :e0005533 , 2017 |
Abstract : Grigoraki_2017_PLoS.Negl.Trop.Dis_11_e0005533 |
ESTHER : Grigoraki_2017_PLoS.Negl.Trop.Dis_11_e0005533 |
PubMedSearch : Grigoraki_2017_PLoS.Negl.Trop.Dis_11_e0005533 |
PubMedID: 28394886 |
Gene_locus related to this paper: aedae-q17b28 , aedae-q17b31 |
Title : In the hunt for genomic markers of metabolic resistance to pyrethroids in the mosquito Aedes aegypti: An integrated next-generation sequencing approach - Faucon_2017_PLoS.Negl.Trop.Dis_11_e0005526 |
Author(s) : Faucon F , Gaude T , Dusfour I , Navratil V , Corbel V , Juntarajumnong W , Girod R , Poupardin R , Boyer F , Reynaud S , David JP |
Ref : PLoS Negl Trop Dis , 11 :e0005526 , 2017 |
Abstract : Faucon_2017_PLoS.Negl.Trop.Dis_11_e0005526 |
ESTHER : Faucon_2017_PLoS.Negl.Trop.Dis_11_e0005526 |
PubMedSearch : Faucon_2017_PLoS.Negl.Trop.Dis_11_e0005526 |
PubMedID: 28379969 |
Gene_locus related to this paper: aedae-q17b31 |
Title : Functional and immunohistochemical characterization of CCEae3a, a carboxylesterase associated with temephos resistance in the major arbovirus vectors Aedes aegypti and Ae. albopictus - Grigoraki_2016_Insect.Biochem.Mol.Biol_74_61 |
Author(s) : Grigoraki L , Balabanidou V , Meristoudis C , Myridakis A , Ranson H , Swevers L , Vontas J |
Ref : Insect Biochemistry & Molecular Biology , 74 :61 , 2016 |
Abstract : Grigoraki_2016_Insect.Biochem.Mol.Biol_74_61 |
ESTHER : Grigoraki_2016_Insect.Biochem.Mol.Biol_74_61 |
PubMedSearch : Grigoraki_2016_Insect.Biochem.Mol.Biol_74_61 |
PubMedID: 27180726 |
Gene_locus related to this paper: aedae-q17b28 , aedae-q17b31 |
Title : Transcriptome Profiling and Genetic Study Reveal Amplified Carboxylesterase Genes Implicated in Temephos Resistance, in the Asian Tiger Mosquito Aedes albopictus - Grigoraki_2015_PLoS.Negl.Trop.Dis_9_e0003771 |
Author(s) : Grigoraki L , Lagnel J , Kioulos I , Kampouraki A , Morou E , Labbe P , Weill M , Vontas J |
Ref : PLoS Negl Trop Dis , 9 :e0003771 , 2015 |
Abstract : Grigoraki_2015_PLoS.Negl.Trop.Dis_9_e0003771 |
ESTHER : Grigoraki_2015_PLoS.Negl.Trop.Dis_9_e0003771 |
PubMedSearch : Grigoraki_2015_PLoS.Negl.Trop.Dis_9_e0003771 |
PubMedID: 26000638 |
Gene_locus related to this paper: aedae-q17b28 , aedae-q17b31 |
Title : Identifying genomic changes associated with insecticide resistance in the dengue mosquito Aedes aegypti by deep targeted sequencing - Faucon_2015_Genome.Res_25_1347 |
Author(s) : Faucon F , Dusfour I , Gaude T , Navratil V , Boyer F , Chandre F , Sirisopa P , Thanispong K , Juntarajumnong W , Poupardin R , Chareonviriyaphap T , Girod R , Corbel V , Reynaud S , David JP |
Ref : Genome Res , 25 :1347 , 2015 |
Abstract : Faucon_2015_Genome.Res_25_1347 |
ESTHER : Faucon_2015_Genome.Res_25_1347 |
PubMedSearch : Faucon_2015_Genome.Res_25_1347 |
PubMedID: 26206155 |
Gene_locus related to this paper: aedae-q17b31 |
Title : Identification of Carboxylesterase Genes Implicated in Temephos Resistance in the Dengue Vector Aedes aegypti - Poupardin_2014_PLoS.Negl.Trop.Dis_8_e2743 |
Author(s) : Poupardin R , Srisukontarat W , Yunta C , Ranson H |
Ref : PLoS Negl Trop Dis , 8 :e2743 , 2014 |
Abstract : Poupardin_2014_PLoS.Negl.Trop.Dis_8_e2743 |
ESTHER : Poupardin_2014_PLoS.Negl.Trop.Dis_8_e2743 |
PubMedSearch : Poupardin_2014_PLoS.Negl.Trop.Dis_8_e2743 |
PubMedID: 24651719 |
Gene_locus related to this paper: aedae-q17b28 , aedae-q17b31 |