Gene_Locus Report

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Gene_locus Report for: aspng-a2qst4

Aspergillus niger Aspergillus kawachii Catalytic activity: cephalosporin C + H2O = deacetylcephalosporin C + acetate precursor (EC 3.1.1.41)

Comment
Other strains: Aspergillus kawachii (strain NBRC 4308) (White koji mold) (Aspergillus awamori var. kawachi)


Relationship
Family|Fungal_carboxylesterase_lipase
Block| C
Position in NCBI Life Tree|Aspergillus niger
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Fungi: N E > Dikarya: N E > Ascomycota: N E > saccharomyceta: N E > Pezizomycotina: N E > leotiomyceta: N E > Eurotiomycetes: N E > Eurotiomycetidae: N E > Eurotiales: N E > Aspergillaceae: N E > Aspergillus: N E > Aspergillus niger: N E
Warning: This entry is a compilation of different species or line or strain with more than 90% amino acide identity. You can retrieve all strain data


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
2 Genbank : AM270186, DF126499
2 UniProt : A2QST4, G7Y0D4
2 UniProt : A2QST4, G7Y0D4
2 Interpro : A2QST4, G7Y0D4
2 Pfam : A2QST4, G7Y0D4
2 PIRSF : A2QST4, G7Y0D4
2 SUPERFAM : A2QST4, G7Y0D4
Sequence
Graphical view for this peptide sequence: aspng-a2qst4
Colored MSA for Fungal_carboxylesterase_lipase (raw)
MHWEYSLVILLGACAVSVDGSPQVDLGYARYRGVRLPAGVDEYLGMRYAA
PPLGQQRFRAPGDPSSTSSIQDAFEFGPTCIGVGEEISPLVGEDCLFINV
FTPSHATTLSRLPVWVHIQGGGYASNANANFNGTNVIQHSGYDLVFVNFN
YRVGALGFLASEEIRRDGDLNVGLLDQRKALAWVKQHISQFGGDPDHIIA
HGDSAGAGSVTHHMTAYGGRAEGLFAGAVLESPFWPTLRTVAEMEFQYTR
FVQRVGCSDASSALACLQSADLAAIQQGNVVDPFPDAAVDPPPLWYFLPV
IDGAVVQDQLSRLFDQGKTVKIPVLVGDDTNEGSTFAYNASDASDMSRFL
NANYPGLSSASLAAIGDAYPRMRPVADHAAYFPSASAAYGDAAFTCPGNR
VAASMADHLPSGRVWSYRYNVRAPELVDEGLGVPHIFELSAIFGVGFAGN
SEITSYNGINANAVATVMDYWISFVKALDPNPRRRSQAPRWEAWKPGLGQ
RLKIQTNTTAMEPIPPQQADRCSLWSALAPEMEI
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MHWEYSLVILLGACAVSVDGSPQVDLGYARYRGVRLPAGVDEYLGMRYAA
PPLGQQRFRAPGDPSSTSSIQDAFEFGPTCIGVGEEISPLVGEDCLFINV
FTPSHATTLSRLPVWVHIQGGGYASNANANFNGTNVIQHSGYDLVFVNFN
YRVGALGFLASEEIRRDGDLNVGLLDQRKALAWVKQHISQFGGDPDHIIA
HGDSAGAGSVTHHMTAYGGRAEGLFAGAVLESPFWPTLRTVAEMEFQYTR
FVQRVGCSDASSALACLQSADLAAIQQGNVVDPFPDAAVDPPPLWYFLPV
IDGAVVQDQLSRLFDQGKTVKIPVLVGDDTNEGSTFAYNASDASDMSRFL
NANYPGLSSASLAAIGDAYPRMRPVADHAAYFPSASAAYGDAAFTCPGNR
VAASMADHLPSGRVWSYRYNVRAPELVDEGLGVPHIFELSAIFGVGFAGN
SEITSYNGINANAVATVMDYWISFVKALDPNPRRRSQAPRWEAWKPGLGQ
RLKIQTNTTAMEPIPPQQADRCSLWSALAPEMEI


References
    Title: Genome sequence of the white koji mold Aspergillus kawachii IFO 4308, used for brewing the Japanese distilled spirit shochu
    Futagami T, Mori K, Yamashita A, Wada S, Kajiwara Y, Takashita H, Omori T, Takegawa K, Tashiro K and Goto M <1 more author(s)>
    Ref: Eukaryot Cell, 10:1586, 2011 : PubMed

            

    Title: Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88
    Pel HJ, de Winde JH, Archer DB, Dyer PS, Hofmann G, Schaap PJ, Turner G, de Vries RP, Albang R and Stam H <59 more author(s)>
    Ref: Nat Biotechnol, 25:221, 2007 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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