aspng-q1ktb5

Aspergillus usamii; Aspergillus niger; Aspergillus lacticoffeatus; Aspergillus brasiliensis AuEH2 Microsomal epoxide hyddrolase (EC 3.3.2.3)

Comment

Other strains: Aspergillus usamii E001\; Aspergillus niger (strain ATCC 1015 \/ CBS 113.46 \/ FGSC A1144 \/ LSHB Ac4 \/ NCTC 3858a \/ NRRL 328 \/ USDA 3528.7) Aspergillus lacticoffeatus CBS 101883\; Aspergillus brasiliensis CBS 101740. The sequence of Aspergillus usamii has been published and the structure of the enzyme is anounced (only 2 residues different between species

Relationship

Family : Epoxide_hydrolase

Block : X

Position in NCBI Life Tree : Aspergillus niger

Molecular evidence

No mutation

No kinetic

No disease

No inhibitor

Sequence

Peptide

MALAYSNIPL GATVIPSPFQ VHISDEQIEE LQLLVKLSKL APPTYEGLQQ DRRYGITNEW LANAKEAWKS FDWRPAESRI NSFPQFTYDI EGLTIHFVAL FSEKKDAIPI VLLHGWPGSF LEFLPVLTSI RDKYSPETLP YHIVVPSLPG YTFSSGPPLD VNFNGEDTAR VINKVMLNLG FEDGYVAQGG DIGSKIGRIL AVDHDACKAV HLNACYMGKP SSIPDTAITE EDKRALARAQ WFATFGSGYA VEHGTRPSTI GNALSTSPVA LLSWIGEKFL DWAGETIPLE TILESVTLYW FTETFPRSIY HYRENFPPPK LRHTEDPRWY IRKPFGFSYY PMELVPTPRA WVETTGNLVF WQAHEKGGHF AALERPQDYL DDLTAFCEQV WAGRK

References

Title : Structure-Guided Regulation in the Enantioselectivity of an Epoxide Hydrolase to Produce Enantiomeric Monosubstituted Epoxides and Vicinal Diols via Kinetic Resolution - Hu_2022_Org.Lett__
Author(s) : Hu D , Hu BC , Hou XD , Zhang D , Lei YQ , Rao YJ , Wu MC
Ref : Org Lett , : , 2022
Abstract : Hu_2022_Org.Lett__
ESTHER : Hu_2022_Org.Lett__
PubMedSearch : Hu_2022_Org.Lett__
PubMedID: 35229602
Gene_locus related to this paper: aspng-q1ktb5

Title : Structure-guided improvement in the enantioselectivity of an Aspergillus usamii epoxide hydrolase for the gram-scale kinetic resolution of ortho-trifluoromethyl styrene oxide - Wen_2021_Enzyme.Microb.Technol_146_109778
Author(s) : Wen Z , Hu D , Hu BC , Zhang D , Huang JF , Wu MC
Ref : Enzyme Microb Technol , 146 :109778 , 2021
Abstract : Wen_2021_Enzyme.Microb.Technol_146_109778
ESTHER : Wen_2021_Enzyme.Microb.Technol_146_109778
PubMedSearch : Wen_2021_Enzyme.Microb.Technol_146_109778
PubMedID: 33812566
Gene_locus related to this paper: aspng-q1ktb5

Title : Nearly perfect kinetic resolution of racemic o-nitrostyrene oxide by AuEH2, a microsomal epoxide hydrolase from Aspergillus usamii, with high enantio- and regio-selectivity - Hu_2021_Int.J.Biol.Macromol_169_1
Author(s) : Hu D , Hu BC , Wen Z , Zhang D , Liu YY , Zang J , Wu MC
Ref : Int J Biol Macromol , 169 :1 , 2021
Abstract : Hu_2021_Int.J.Biol.Macromol_169_1
ESTHER : Hu_2021_Int.J.Biol.Macromol_169_1
PubMedSearch : Hu_2021_Int.J.Biol.Macromol_169_1
PubMedID: 33316339
Gene_locus related to this paper: aspng-q1ktb5

Title : Near-perfect kinetic resolution of racemic p-chlorostyrene oxide by SlEH1, a novel epoxide hydrolase from Solanum lycopersicum with extremely high enantioselectivity - Hu_2020_Int.J.Biol.Macromol_147_1213
Author(s) : Hu BC , Hu D , Li C , Xu XF , Wen Z , Wu MC
Ref : Int J Biol Macromol , 147 :1213 , 2020
Abstract : Hu_2020_Int.J.Biol.Macromol_147_1213
ESTHER : Hu_2020_Int.J.Biol.Macromol_147_1213
PubMedSearch : Hu_2020_Int.J.Biol.Macromol_147_1213
PubMedID: 31739010
Gene_locus related to this paper: aspng-q1ktb5

Title : Enantioconvergent hydrolysis of racemic styrene oxide at high concentration by a pair of novel epoxide hydrolases into (R)-phenyl-1,2-ethanediol - Wang_2017_Biotechnol.Lett_39_1917
Author(s) : Wang R , Hu D , Zong X , Li J , Ding L , Wu M
Ref : Biotechnol Lett , 39 :1917 , 2017
Abstract : Wang_2017_Biotechnol.Lett_39_1917
ESTHER : Wang_2017_Biotechnol.Lett_39_1917
PubMedSearch : Wang_2017_Biotechnol.Lett_39_1917
PubMedID: 28875350
Gene_locus related to this paper: vigra-Vreh3 , aspng-q1ktb5

Title : Kinetic resolution of racemic styrene oxide at a high concentration by recombinant Aspergillus usamii epoxide hydrolase in an n-hexanol\/buffer biphasic system - Hu_2016_J.Biotechnol_236_152
Author(s) : Hu D , Wang R , Shi XL , Ye HH , Wu Q , Wu MC , Chu JJ
Ref : J Biotechnol , 236 :152 , 2016
Abstract : Hu_2016_J.Biotechnol_236_152
ESTHER : Hu_2016_J.Biotechnol_236_152
PubMedSearch : Hu_2016_J.Biotechnol_236_152
PubMedID: 27546798
Gene_locus related to this paper: aspng-q1ktb5

Title : Expression of a novel epoxide hydrolase of Aspergillus usamii E001 in Escherichia coli and its performance in resolution of racemic styrene oxide - Hu_2015_J.Ind.Microbiol.Biotechnol_42_671
Author(s) : Hu D , Tang CD , Yang B , Liu JC , Yu T , Deng C , Wu MC
Ref : J Ind Microbiol Biotechnol , 42 :671 , 2015
Abstract : Hu_2015_J.Ind.Microbiol.Biotechnol_42_671
ESTHER : Hu_2015_J.Ind.Microbiol.Biotechnol_42_671
PubMedSearch : Hu_2015_J.Ind.Microbiol.Biotechnol_42_671
PubMedID: 25733186
Gene_locus related to this paper: aspng-q1ktb5