(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) > cellular organisms: NE > Bacteria: NE > Terrabacteria group: NE > Firmicutes: NE > Bacilli: NE > Bacillales: NE > Bacillaceae: NE > Bacillus: NE > Bacillus cereus group: NE > Bacillus anthracis: NE
Warning: This entry is a compilation of different species or line or strain with more than 90% amino acide identity. You can retrieve all strain data
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) Bacillus anthracis str. CDC 684: N, E.
Bacillus anthracis str. A0465: N, E.
Bacillus anthracis str. Ames: N, E.
Bacillus anthracis str. A0248: N, E.
Bacillus anthracis str. A0488: N, E.
Bacillus anthracis str. A0193: N, E.
Bacillus anthracis str. A0442: N, E.
Bacillus anthracis str. A0389: N, E.
Bacillus anthracis str. A0174: N, E.
Bacillus anthracis Tsiankovskii-I: N, E.
Bacillus anthracis str. A2012: N, E.
Bacillus anthracis str. BF1: N, E.
Bacillus anthracis str. SVA11: N, E.
Bacillus anthracis str. H9401: N, E.
Bacillus anthracis str. A16: N, E.
Bacillus anthracis CZC5: N, E.
Bacillus anthracis 8903-G: N, E.
Bacillus anthracis 9080-G: N, E.
Bacillus anthracis 52-G: N, E.
Bacillus anthracis str. A16R: N, E.
Bacillus anthracis str. UR-1: N, E.
Bacillus anthracis str. Tsiankovskii-I: N, E.
Bacillus cereus BGSC 6E1: N, E.
Bacillus cereus 03BB108: N, E.
Bacillus cereus 03BB102: N, E.
Molecular evidence
Database
No mutation 1 structure: 3I1I: X-ray crystal structure of homoserine O-acetyltransferase from Bacillus anthracis. No kinetic
LegendThis sequence has been compared to family alignement (MSA) red => minority aminoacid blue => majority aminoacid color intensity => conservation rate title => sequence position(MSA position)aminoacid rate Catalytic site Catalytic site in the MSA SNAMQIVKKEKFILKEYTFENGRTIPVQMGYETYGTLNRERSNVILICHY FSATSHAAGKYTAHDEESGWWDGLIGPGKAIDTNQYFVICTDNLCNVQVK NPHVITTGPKSINPKTGDEYAMDFPVFTFLDVARMQCELIKDMGIARLHA VMGPSAGGMIAQQWAVHYPHMVERMIGVITNPQNPIITSVNVAQNAIEAI RLDPSWKGGKYGEEQPMKGLQLANRMMFMNAFDEHFYETTYPRNSIEVEP YEKVSSLTSFEKEINKLTYRSIELVDANSWMYTAKAVLLHDIAHGFSSLE EALSNVEANVLMIPCKQDLLQPSRYNYKMVDLLQKQGKYAEVYEIESING HMAGVFDIHLFEKKVYEFLNRKVSSFV
Bacillus anthracis is an endospore-forming bacterium that causes inhalational anthrax. Key virulence genes are found on plasmids (extra-chromosomal, circular, double-stranded DNA molecules) pXO1 (ref. 2) and pXO2 (ref. 3). To identify additional genes that might contribute to virulence, we analysed the complete sequence of the chromosome of B. anthracis Ames (about 5.23 megabases). We found several chromosomally encoded proteins that may contribute to pathogenicity--including haemolysins, phospholipases and iron acquisition functions--and identified numerous surface proteins that might be important targets for vaccines and drugs. Almost all these putative chromosomal virulence and surface proteins have homologues in Bacillus cereus, highlighting the similarity of B. anthracis to near-neighbours that are not associated with anthrax. By performing a comparative genome hybridization of 19 B. cereus and Bacillus thuringiensis strains against a B. anthracis DNA microarray, we confirmed the general similarity of chromosomal genes among this group of close relatives. However, we found that the gene sequences of pXO1 and pXO2 were more variable between strains, suggesting plasmid mobility in the group. The complete sequence of B. anthracis is a step towards a better understanding of anthrax pathogenesis.
Bacillus anthracis, Bacillus cereus, Homoserine O-acetyltransferase, putative
