bacsu-srfac

 
Bacillus subtilis surfactin synthetase subunit 3

Comment
only c-term Pfam A Thioesterase 1059 1271


Relationship
Block X
Bacillus subtilis position in NCBI Life Tree :
N link to NCBI taxonomic web page and E link to ESTHER gene locus found in this strain.
> cellular organisms: N E > Bacteria: N E > Terrabacteria group: N E > Firmicutes: N E > Bacilli: N E > Bacillales: N E > Bacillaceae: N E > Bacillus: N E > Bacillus subtilis group: N E > Bacillus subtilis: N E
Warning: This entry is a compilation of different species or line or strain with more than 90% amino acide identity. You can retrieve all strain data


Molecular evidence
Database
No mutation
2 structures: 1JMK, 2VSQ
No kinetic



3 Genbank : X70356, D50453, Z99105
1 UniProt : Q08787
2 Structure : 1JMK, 2VSQ
1 UniProtTrembl : Q08787
1 Interpro : Q08787
1 Prodom : Q08787
1 Pfam : Q08787
1 PIRSF : Q08787
1 SUPERFAM : Q08787
1 QuickSwissBlast : Q08787
 
Sequence
Graphical view for this peptide sequence: bacsu-srfac
Colored MSA for Thioesterase (raw)
VKDAVVVADRHESGDASINAYLVNRTQLSAEDVKAHLKKQLPAYMVPQTF
TFLDELPLTTNGKVNKRLLPKPDQDQLAEEWIGPRNEMEETIAQIWSEVL
GRKQIGIHDDFFALGGHSLKAMTAVPHQQELGIDLPVKLLFEAPTIAGIS
AYLKNGGSDGLQDVTIMNQDQEQIIFAFPPVLGYGLMYQNLSSRLPSYKL
CAFDFIEEEDRLDRYADLIQKLQPEGPLTLFGYSAGCSLAFEAAKKLEEQ
GRIVQRIIMVDSYKKQGVSDLDGRTVESDVEALMNVNRDNEALNSEAVKH
GLKQKTHAFYSYYVNLISTGQVKADIDLLTSGADFDMPEWLASWEEATTG
VYRVKRGFGTHAEMLQGETLDRNAEILLEFLNTQTVTVS
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

VKDAVVVADRHESGDASINAYLVNRTQLSAEDVKAHLKKQLPAYMVPQTF
TFLDELPLTTNGKVNKRLLPKPDQDQLAEEWIGPRNEMEETIAQIWSEVL
GRKQIGIHDDFFALGGHSLKAMTAVPHQQELGIDLPVKLLFEAPTIAGIS
AYLKNGGSDGLQDVTIMNQDQEQIIFAFPPVLGYGLMYQNLSSRLPSYKL
CAFDFIEEEDRLDRYADLIQKLQPEGPLTLFGYSAGCSLAFEAAKKLEEQ
GRIVQRIIMVDSYKKQGVSDLDGRTVESDVEALMNVNRDNEALNSEAVKH
GLKQKTHAFYSYYVNLISTGQVKADIDLLTSGADFDMPEWLASWEEATTG
VYRVKRGFGTHAEMLQGETLDRNAEILLEFLNTQTVTVS

no DNA




References
2 more
    Title: Crystal structure of the termination module of a nonribosomal peptide synthetase
    Tanovic A, Samel SA, Essen LO, Marahiel MA
    Ref: Science, 321:659, 2008 : PubMed

            

    Title: The 25 degrees-36 degrees region of the Bacillus subtilis chromosome: determination of the sequence of a 146 kb segment and identification of 113 genes
    Yamane K, Kumano M, Kurita K
    Ref: Microbiology, 142 ( Pt 11):3047, 1996 : PubMed

            

    Title: Sequence and analysis of the genetic locus responsible for surfactin synthesis in Bacillus subtilis
    Cosmina P, Rodriguez F, de Ferra F, Grandi G, Perego M, Venema G, van Sinderen D
    Ref: Molecular Microbiology, 8:821, 1993 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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