boomi-ACHE3

Boophilus microplus (Cattle tick) putative acetylcholinesterase 3 AChE3 mRNA

Comment

R86Q mutant exhibits 19.2-fold reduced sensitivity to paraoxon. The following mutations were found associated with OP resistant strains, but were also found in susceptible strains and were not characterized biochemically, I48L, I54V, V71A, I77M, S79P, I123M, I492M, T548A, T548Y see: Jyoti et al. 2016

Relationship

Family : ACHE

Block : C

Position in NCBI Life Tree : Boophilus microplus

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Sequence

Peptide

MYSRIVVLLL YGYALRSAHA RCYIFQPGDP IQDTDEKIYL AQPFNVTIPL EAGIPTTAQP ASTGKDQLSL VVPPDDIQSL STTTSRPIST EESPIVETNS GPVQGRRVYA ANRTLYQFVG IPFAEPPVGP LRFRNPVPVK PWSSVYQATK KPFPCLQTDF YINSNVTIPT ANSSEDCLYL NVWTPSRECV LGKFSCVPKT VIVYIYGGTF SFGSSGWDWY DGKEFVARGD VVMVSMNYRV GPMGFFHSGT THSSGNAGLH DQLLAMKWVK QNIRNFGGDP DDVTLVGQSA GAISIGLHLV SPLSKGLFKR IIMESGSPYF RIADNTREGP HKVEKLARAL QCARNDMTIE SHMAEMVECL RKIDGKELLI MSNTIFGVHA LTFFPVFGDD IIPDDPYLMM EQKKFHKADL LIGNNLDEGS YFVFYLFGRA LDLEQAHKIT KYEVDLYVSY CLQMLLRKNV SPIRHYYLSH IGERENIKAL QKAAEAVGDF AIICPTKYFA ESFASMNNKV HYYYFTHRPS FSTWPGWVGP THGDEVFFVM GLPFSSPTIA TDQERELSKL MIETWTTFAK TGKVPDVASK PWPEFTAKNQ VYMELNPKRY TYGRGPNEKN CNFWKSYLKP RGPNEKNCNF WKSYLKP

References

Title : Molecular biology of tick acetylcholinesterases - Temeyer_2018_Front.Biosci.(Landmark.Ed)_23_1320
Author(s) : Temeyer KB
Ref : Front Biosci (Landmark Ed) , 23 :1320 , 2018
Abstract : Temeyer_2018_Front.Biosci.(Landmark.Ed)_23_1320
ESTHER : Temeyer_2018_Front.Biosci.(Landmark.Ed)_23_1320
PubMedSearch : Temeyer_2018_Front.Biosci.(Landmark.Ed)_23_1320
PubMedID: 28930602
Gene_locus related to this paper: boomi-ACHE1 , boomi-ACHE2 , boomi-ACHE3

Title : Multiple mutations in the acetylcholinesterase 3 gene associated with organophosphate resistance in Rhipicephalus (Boophilus) microplus ticks from Punjab, India - Jyoti_2016_Vet.Parasitol_216_108
Author(s) : Jyoti , Singh NK , Singh H , Rath SS
Ref : Vet Parasitol , 216 :108 , 2016
Abstract : Jyoti_2016_Vet.Parasitol_216_108
ESTHER : Jyoti_2016_Vet.Parasitol_216_108
PubMedSearch : Jyoti_2016_Vet.Parasitol_216_108
PubMedID: 26801603
Gene_locus related to this paper: boomi-ACHE3

Title : Inhibitor profile of (n)-tacrines -methylcarbamates on acetylcholinesterase from Rhipicephalus (Boophilus) microplus and Phlebotomus papatasi - Swale_2013_Pestic.Biochem.Physiol_106_
Author(s) : Swale DR , Tong F , Temeyer KB , Li A , Lam PC , Totrov MM , Carlier PR , Perez de Leon AA , Bloomquist JR
Ref : Pesticide Biochemistry and Physiology , 106 : , 2013
Abstract : Swale_2013_Pestic.Biochem.Physiol_106_
ESTHER : Swale_2013_Pestic.Biochem.Physiol_106_
PubMedSearch : Swale_2013_Pestic.Biochem.Physiol_106_
PubMedID: 24187393
Gene_locus related to this paper: boomi-ACHE1 , boomi-ACHE2 , boomi-ACHE3

Title : Acetylcholinesterase of Rhipicephalus (Boophilus) microplus and Phlebotomus papatasi: Gene identification, expression, and biochemical properties of recombinant proteins - Temeyer_2013_Pestic.Biochem.Physiol_106_118
Author(s) : Temeyer KB , Olafson PU , Brake DK , Tuckow AP , Li AY , Perez de Leon AA
Ref : Pesticide Biochemistry and Physiology , 106 :118 , 2013
Abstract : Temeyer_2013_Pestic.Biochem.Physiol_106_118
ESTHER : Temeyer_2013_Pestic.Biochem.Physiol_106_118
PubMedSearch : Temeyer_2013_Pestic.Biochem.Physiol_106_118
PubMedID:
Gene_locus related to this paper: boomi-ACHE1 , boomi-ACHE2 , boomi-ACHE3

Title : Sequence polymorphism in acetylcholinesterase transcripts and genotyping survey of BmAchE1 in laboratory and Mexican strains of Rhipicephalus (Boophilus) microplus - Temeyer_2012_J.Med.Entomol_49_555
Author(s) : Temeyer KB , Olafson PU , Pruett JH
Ref : Journal of Medical Entomology , 49 :555 , 2012
Abstract : Temeyer_2012_J.Med.Entomol_49_555
ESTHER : Temeyer_2012_J.Med.Entomol_49_555
PubMedSearch : Temeyer_2012_J.Med.Entomol_49_555
PubMedID: 22679862
Gene_locus related to this paper: boomi-ACHE1 , boomi-ACHE2 , boomi-ACHE3

Title : Genetic factors potentially reducing fitness cost of organophosphate insensitive acetylcholinesterase(s) in Rhipicephalus (Boophilus) microplus - Temeyer_2011_Zoosymposia_6_260
Author(s) : Temeyer KB , Tijerina MA , Davey RB , Olafson PU
Ref : Zoosymposia , 6 :260 , 2011
Abstract : Temeyer_2011_Zoosymposia_6_260
ESTHER : Temeyer_2011_Zoosymposia_6_260
PubMedSearch : Temeyer_2011_Zoosymposia_6_260
PubMedID:
Gene_locus related to this paper: boomi-ACHE1 , boomi-ACHE2 , boomi-ACHE3

Title : Baculovirus expression, biochemical characterization and organophosphate sensitivity of rBmAChE1, rBmAChE2, and rBmAChE3 of Rhipicephalus (Boophilus) microplus - Temeyer_2010_Vet.Parasitol_172_114
Author(s) : Temeyer KB , Pruett JH , Olafson PU
Ref : Vet Parasitol , 172 :114 , 2010
Abstract : Temeyer_2010_Vet.Parasitol_172_114
ESTHER : Temeyer_2010_Vet.Parasitol_172_114
PubMedSearch : Temeyer_2010_Vet.Parasitol_172_114
PubMedID: 20451328
Gene_locus related to this paper: boomi-ACHE1 , boomi-ACHE2 , boomi-ACHE3

Title : Genotyping mutations in BmAChE3: A survey of organophosphate-resistant and -susceptible strains of Rhipicephalus (Boophilus) microplus - Temeyer_2009_J.Med.Entomol_46_1355
Author(s) : Temeyer KB , Olafson PU , Miller RJ
Ref : Journal of Medical Entomology , 46 :1355 , 2009
Abstract : Temeyer_2009_J.Med.Entomol_46_1355
ESTHER : Temeyer_2009_J.Med.Entomol_46_1355
PubMedSearch : Temeyer_2009_J.Med.Entomol_46_1355
PubMedID: 19960680
Gene_locus related to this paper: boomi-ACHE3

Title : R86Q, a mutation in BmAChE3 yielding a Rhipicephalus microplus organophosphate-insensitive acetylcholinesterase - Temeyer_2007_J.Med.Entomol_44_1013
Author(s) : Temeyer KB , Pruett JH , Olafson PU , Chen AC
Ref : Journal of Medical Entomology , 44 :1013 , 2007
Abstract : Temeyer_2007_J.Med.Entomol_44_1013
ESTHER : Temeyer_2007_J.Med.Entomol_44_1013
PubMedSearch : Temeyer_2007_J.Med.Entomol_44_1013
PubMedID: 18047200
Gene_locus related to this paper: boomi-ACHE3

Title : Baculovirus expression of BmAChE3, a cDNA encoding an acetylcholinesterase of Boophilus microplus (Acari: Ixodidae) - Temeyer_2006_J.Med.Entomol_43_707
Author(s) : Temeyer KB , Pruett JH , Untalan PM , Chen AC
Ref : Journal of Medical Entomology , 43 :707 , 2006
Abstract : Temeyer_2006_J.Med.Entomol_43_707
ESTHER : Temeyer_2006_J.Med.Entomol_43_707
PubMedSearch : Temeyer_2006_J.Med.Entomol_43_707
PubMedID: 16892628
Gene_locus related to this paper: boomi-ACHE3

Title : Identification of a third Boophilus microplus (Acari: Ixodidae) cDNA presumptively encoding an acetylcholinesterase - Temeyer_2004_J.Med.Entomol_41_259
Author(s) : Temeyer KB , Davey RB , Chen AC
Ref : Journal of Medical Entomology , 41 :259 , 2004
Abstract : Temeyer_2004_J.Med.Entomol_41_259
ESTHER : Temeyer_2004_J.Med.Entomol_41_259
PubMedSearch : Temeyer_2004_J.Med.Entomol_41_259
PubMedID: 15185924
Gene_locus related to this paper: boomi-ACHE3