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caeel-NLGN1

Caenorhabditis elegans Neuroligin C40C9.5a gene Y12A6A.a

Comment

Neuroligins function as ligands for the neurexin family and MADD-4. This interaction is necessary for GABA receptors clustering.

Relationship

Family : Neuroligin

Block : C

Position in NCBI Life Tree : Caenorhabditis elegans

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

MERIYLLLLL FLPRIRSYDV RSVTTSWGMV RGEVVSPEGD DLPPVAQYLG IPYGVAPTGQ YRFNMAISAA KWTHMPKDAR KVSPVCIQTD MPELSETKRF RAFKHTSAQR FDFNHRLLPH LKKQSEDCLY MNIYVPERLE ISRDNYLPVM VIVHGEEYGW GTGNAFNGTT LAAYGHIIVV TLNYRLGVFG FLGRCESSSC SGNSGISDLV SALTMLNVIL PSFGGDSKSV TLAGWGSGAS LVSLLMASPL TQPGRRLFRR AILLDGSALS PWAISQNPQQ YFMQLAEELA CAPKNRTSSF NDNVDTIVRC MQVHSSENIT KAVLKIDVPT FLSGFAPIVD GQLIPNKPQV SFSTQYGSLF REIDLLVGIS SNPSHHMISN EDLKVGISKE KRMRIFRSLV RNLYDFHREE ILASIINEYT DWENPRDHPK SIRNGVLNAL SDVLYTAPLI ETLRSHSADE VRKEANTFMF AFAHETRSWS QEQPNSGIRG SLSGDIVPYI FGYPLAQGDS EERLYSGFNT DDKGISKVMM HYVSNFVKSG DPSKPNPMSK NFPMGDVFHS TAWPQFDQPN REAYLEITDR PRVKNYYRNA QVGFWNNFIP QLHKNGKETE PVGEEHHLLS DHFRKDSYFG KTRHFSSYAN LPFPPPPMPP SPPPELTTKP KPSESPTTLQ TTTESEKAAA GSFTGKALGG VIFIGCGFLI MNVCLLIAVR REWGKKRRNE KKFQLQYQTY NSNHGGGAEQ YNSLNSPLSL MPPPPPPLNG VHDDIFDHRV PHLRNGSTVH GTLPRHSFQE QEPLLSASHK NSTSMRPAGI SPTCPRHGRA ALALQNSRGN SLTAAQAPTL EEIQV

References

Title : Graphene oxide disrupts the protein-protein interaction between Neuroligin\/NLG-1 and DLG-1 or MAGI-1 in nematode Caenorhabditis elegans - Zhao_2019_Sci.Total.Environ_700_134492
Author(s) : Zhao Y , Chen H , Yang Y , Wu Q , Wang D
Ref : Sci Total Environ , 700 :134492 , 2019
Abstract : Zhao_2019_Sci.Total.Environ_700_134492
ESTHER : Zhao_2019_Sci.Total.Environ_700_134492
PubMedSearch : Zhao_2019_Sci.Total.Environ_700_134492
PubMedID: 31627046
Gene_locus related to this paper: caeel-NLGN1 , human-NLGN1

Title : Analysis of splice variants for the C. elegans orthologue of human neuroligin reveals a developmentally regulated transcript - Calahorro_2015_Gene.Expr.Patterns_17_69
Author(s) : Calahorro F , Holden-Dye L , O'Connor V
Ref : Gene Expr Patterns , 17 :69 , 2015
Abstract : Calahorro_2015_Gene.Expr.Patterns_17_69
ESTHER : Calahorro_2015_Gene.Expr.Patterns_17_69
PubMedSearch : Calahorro_2015_Gene.Expr.Patterns_17_69
PubMedID: 25726726
Gene_locus related to this paper: caeel-NLGN1

Title : C. elegans Punctin Clusters GABA Receptors via Neuroligin Binding and UNC-40\/DCC Recruitment - Tu_2015_Neuron_86_1407
Author(s) : Tu H , Pinan-Lucarre B , Ji T , Jospin M , Bessereau JL
Ref : Neuron , 86 :1407 , 2015
Abstract : Tu_2015_Neuron_86_1407
ESTHER : Tu_2015_Neuron_86_1407
PubMedSearch : Tu_2015_Neuron_86_1407
PubMedID: 26028575
Gene_locus related to this paper: caeel-NLGN1

Title : MADD-4\/Punctin and Neurexin Organize C. elegans GABAergic Postsynapses through Neuroligin - Maro_2015_Neuron_86_1420
Author(s) : Maro GS , Gao S , Olechwier AM , Hung WL , Liu M , Ozkan E , Zhen M , Shen K
Ref : Neuron , 86 :1420 , 2015
Abstract : Maro_2015_Neuron_86_1420
ESTHER : Maro_2015_Neuron_86_1420
PubMedSearch : Maro_2015_Neuron_86_1420
PubMedID: 26028574
Gene_locus related to this paper: caeel-NLGN1

Title : C. elegans Punctin specifies cholinergic versus GABAergic identity of postsynaptic domains - Pinan-Lucarre_2014_Nature_511_466
Author(s) : Pinan-Lucarre B , Tu H , Pierron M , Cruceyra PI , Zhan H , Stigloher C , Richmond JE , Bessereau JL
Ref : Nature , 511 :466 , 2014
Abstract : Pinan-Lucarre_2014_Nature_511_466
ESTHER : Pinan-Lucarre_2014_Nature_511_466
PubMedSearch : Pinan-Lucarre_2014_Nature_511_466
PubMedID: 24896188
Gene_locus related to this paper: caeel-NLGN1

Title : Neuroligin-deficient mutants of C. elegans have sensory processing deficits and are hypersensitive to oxidative stress and mercury toxicity - Hunter_2010_Dis.Model.Mech_3_366
Author(s) : Hunter JW , Mullen GP , McManus JR , Heatherly JM , Duke A , Rand JB
Ref : Dis Model Mech , 3 :366 , 2010
Abstract : Hunter_2010_Dis.Model.Mech_3_366
ESTHER : Hunter_2010_Dis.Model.Mech_3_366
PubMedSearch : Hunter_2010_Dis.Model.Mech_3_366
PubMedID: 20083577
Gene_locus related to this paper: caeel-NLGN1

Title : Osmotic avoidance in Caenorhabditis elegans: synaptic function of two genes, orthologues of human NRXN1 and NLGN1, as candidates for autism - Calahorro_2009_J.Vis.Exp_34_1616
Author(s) : Calahorro F , Alejandre E , Ruiz-Rubio M
Ref : J Vis Exp , 34 :1616 , 2009
Abstract : Calahorro_2009_J.Vis.Exp_34_1616
ESTHER : Calahorro_2009_J.Vis.Exp_34_1616
PubMedSearch : Calahorro_2009_J.Vis.Exp_34_1616
PubMedID: 20010541
Gene_locus related to this paper: caeel-NLGN1

Title : Genome sequence of the nematode C. elegans: a platform for investigating biology. The C. elegans Sequencing Consortium - CEGSC_1998_Science_282_2012
Author(s) : CEGSC
Ref : Science , 282 :2012 , 1998
Abstract : CEGSC_1998_Science_282_2012
ESTHER : CEGSC_1998_Science_282_2012
PubMedSearch : CEGSC_1998_Science_282_2012
PubMedID: 9851916
Gene_locus related to this paper: caeel-1llip , caeel-ACHE1 , caeel-ACHE2 , caeel-ACHE3 , caeel-ACHE4 , caeel-b0238.1 , caeel-b0238.2 , caeel-b0238.7 , caeel-c01b10.4 , caeel-c01b10.10 , caeel-C04B4.3 , caeel-c08h9.1 , caeel-C09D4.4 , caeel-C09E8.2 , caeel-c17h12.4 , caeel-c23h4.2 , caeel-c23h4.3 , caeel-c23h4.7 , caeel-C25A1.12 , caeel-C25G4.2 , caeel-C26B9.5 , caeel-C27C12.7 , caeel-C31H5.1 , caeel-C31H5.6 , caeel-C37H5.2 , caeel-C37H5.3 , caeel-C39B5.5 , caeel-C40H1.7 , caeel-C41A3.1 , caeel-c42d4.2 , caeel-C45B11.6 , caeel-C46C11.1 , caeel-C50B6.9 , caeel-C52A10.1 , caeel-C54G4.7 , caeel-D1022.3 , caeel-D1022.4 , caeel-D2024.2 , caeel-E01G6.3 , caeel-ester , caeel-F01D5.7 , caeel-F01D5.8 , caeel-F01F1.5 , caeel-F01G10.7 , caeel-F10D2.10 , caeel-F10F2.3 , caeel-F11C1.4 , caeel-f13d12.6 , caeel-F14E5.5 , caeel-f15a8.6 , caeel-f16f9.4 , caeel-F19C7.2 , caeel-F19C7.4 , caeel-O02252.1 , caeel-O02252.2 , caeel-G5EFJ8.1 , caeel-G5EFJ8.2 , caeel-F25A2.1 , caeel-F26A3.1 , caeel-f27c8.6 , caeel-F28H7.3 , caeel-F31F6.7 , caeel-f32a5.3 , caeel-F32B4.6 , caeel-F32H2.5 , caeel-F35H12.5 , caeel-f41c3.5 , caeel-F42G9.6 , caeel-f44b9.1 , caeel-F44C4.5 , caeel-F45E6.4 , caeel-F46B6.8 , caeel-F46G10.4 , caeel-F54F3.3 , caeel-f55d10.3 , caeel-f55f3.c , caeel-f56c11.6 , caeel-F58G1.5 , caeel-ges1e , caeel-H41C03.2 , caeel-K01A2.5 , caeel-K02F2.1 , caeel-K02F3.6 , caeel-K03H6.2 , caeel-K04A8.5 , caeel-K04G2.2 , caeel-K04G2.5 , caeel-K05B2.4 , caeel-K07C5.5 , caeel-k07c11.4 , caeel-K08B12.1 , caeel-K08D9.4 , caeel-k10b2.2 , caeel-K10C2.1.1 , caeel-K10C2.1.2 , caeel-K10C2.1.3 , caeel-K10C2.1.4 , caeel-k11g9.1 , caeel-k11g9.2 , caeel-K12B6.3 , caeel-M05B5.4 , caeel-pafa , caeel-PCP5 , caeel-ppme1 , caeel-q4r165 , caeel-q5fc17 , caeel-q7m3k8 , caeel-q7yx60 , caeel-q7yx61 , caeel-q9tzh8 , caeel-q9tzh9 , caeel-q336k8 , caeel-q17846 , caeel-q22750 , caeel-q22992 , caeel-R05D7.4 , caeel-R11E3.8 , caeel-R11G11.14 , caeel-T01C3.4 , caeel-t02b5.1 , caeel-t02b5.3 , caeel-T05E7.1 , caeel-T07H6.1 , caeel-T08B1.4 , caeel-t09b9.1 , caeel-T10B5.7 , caeel-T12A7.4 , caeel-T19B10.8 , caeel-T21H3.1 , caeel-t22d1.11 , caeel-T23F1.7 , caeel-T23F4.3 , caeel-t28c12.4 , caeel-tmco4 , caeel-W01A11.1 , caeel-W03D8.8 , caeel-W03G9.6 , caeel-NLGN1 , caeel-Y16B4A.2 , caeel-Y32F6A.5 , caeel-Y38E10A.7 , caeel-Y40D12A.2 , caeel-Y43F8A.3 , caeel-Y46H3A.4 , caeel-Y48G10A.1 , caeel-Y48G10A.3 , caeel-Y49E10.16 , caeel-Y49E10.18 , caeel-Y49E10.25 , caeel-Y50E8A.7 , caeel-Y51H4A.5 , caeel-Y55F3AM.10 , caeel-Y57E12B.3 , caeel-Y60A3A.7 , caeel-Y71G12A.4 , caeel-Y71H2AM.K , caeel-Y73C8B.1 , caeel-Y73C8B.2 , caeel-Y73C8B.3 , caeel-Y75b8.3 , caeel-Y97E10AL.2 , caeel-Y110A7A.7 , caeel-q9grv9.1 , caeel-q9grv9.2 , caeel-ydj1 , caeel-ym9i , caeel-ym67 , caeel-yog1 , caeel-ypt1 , caeel-yyc5 , caeel-zc376.1 , caeel-zc376.2 , caeel-zc376.3 , caeel-ZK262.2 , caeel-ZK262.3 , caeel-ZK617.2 , caeel-f172a