(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) > cellular organisms: NE > Bacteria: NE > Proteobacteria: NE > delta/epsilon subdivisions: NE > Epsilonproteobacteria: NE > Campylobacterales: NE > Campylobacteraceae: NE > Campylobacter: NE > Campylobacter jejuni: NE
Warning: This entry is a compilation of different species or line or strain with more than 90% amino acid identity. You can retrieve all strain data
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) Campylobacter jejuni subsp. doylei: N, E.
Campylobacter jejuni subsp. jejuni 414: N, E.
Campylobacter jejuni subsp. jejuni: N, E.
Campylobacter jejuni RM1221: N, E.
Campylobacter jejuni subsp. jejuni 81-176: N, E.
Campylobacter jejuni subsp. doylei 269.97: N, E.
Campylobacter jejuni subsp. jejuni 1336: N, E.
Campylobacter jejuni subsp. jejuni IA3902: N, E.
Campylobacter jejuni subsp. jejuni 84-25: N, E.
Campylobacter jejuni subsp. jejuni HB93-13: N, E.
Campylobacter jejuni subsp. jejuni 260.94: N, E.
Campylobacter jejuni subsp. jejuni CF93-6: N, E.
Campylobacter jejuni subsp. jejuni CG8421: N, E.
Campylobacter jejuni subsp. jejuni CG8486: N, E.
Campylobacter jejuni subsp. jejuni S3: N, E.
Campylobacter jejuni subsp. jejuni M1: N, E.
Campylobacter jejuni subsp. jejuni 327: N, E.
Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819: N, E.
Campylobacter jejuni subsp. jejuni DFVF1099: N, E.
Campylobacter jejuni subsp. jejuni 305: N, E.
Campylobacter jejuni subsp. jejuni 81116: N, E.
Campylobacter jejuni subsp. jejuni ICDCCJ07001: N, E.
Campylobacter jejuni K5: N, E.
Campylobacter jejuni 30318: N, E.
Campylobacter jejuni subsp. jejuni 2008-988: N, E.
LegendThis sequence has been compared to family alignement (MSA) red => minority aminoacid blue => majority aminoacid color intensity => conservation rate title => sequence position(MSA position)aminoacid rate Catalytic site Catalytic site in the MSA MAQTQLSYKNKTYQISYEILGDLSLPQILILHGWGADKKLMKQSFCPFLK DFCQIYMDLAGFGNSSVEEILNTQDYANITELFLKQKKLNVCFFMGHSFG GKVSTLLAKEKDTLILLSSAGILAKKSLKVRFKIRIFKILKLFGLGKFYR YFASKDGANLSPIMYETFKKVVDEDFSEIFAKQKAKSLIFWGKSDEATPL YCGEKMHQFLKNSTFYPLEGDHFFFLKHSAFIAQKIKEI
Sequencing and comparative genome analysis of four strains of Campylobacter including C. lari RM2100, C. upsaliensis RM3195, and C. coli RM2228 has revealed major structural differences that are associated with the insertion of phage- and plasmid-like genomic islands, as well as major variations in the lipooligosaccharide complex. Poly G tracts are longer, are greater in number, and show greater variability in C. upsaliensis than in the other species. Many genes involved in host colonization, including racR/S, cadF, cdt, ciaB, and flagellin genes, are conserved across the species, but variations that appear to be species specific are evident for a lipooligosaccharide locus, a capsular (extracellular) polysaccharide locus, and a novel Campylobacter putative licABCD virulence locus. The strains also vary in their metabolic profiles, as well as their resistance profiles to a range of antibiotics. It is evident that the newly identified hypothetical and conserved hypothetical proteins, as well as uncharacterized two-component regulatory systems and membrane proteins, may hold additional significant information on the major differences in virulence among the species, as well as the specificity of the strains for particular hosts.
Campylobacter jejuni, from the delta-epsilon group of proteobacteria, is a microaerophilic, Gram-negative, flagellate, spiral bacterium-properties it shares with the related gastric pathogen Helicobacter pylori. It is the leading cause of bacterial food-borne diarrhoeal disease throughout the world. In addition, infection with C. jejuni is the most frequent antecedent to a form of neuromuscular paralysis known as Guillain-Barre syndrome. Here we report the genome sequence of C. jejuni NCTC11168. C. jejuni has a circular chromosome of 1,641,481 base pairs (30.6% G+C) which is predicted to encode 1,654 proteins and 54 stable RNA species. The genome is unusual in that there are virtually no insertion sequences or phage-associated sequences and very few repeat sequences. One of the most striking findings in the genome was the presence of hypervariable sequences. These short homopolymeric runs of nucleotides were commonly found in genes encoding the biosynthesis or modification of surface structures, or in closely linked genes of unknown function. The apparently high rate of variation of these homopolymeric tracts may be important in the survival strategy of C. jejuni.
