Gene_locus Report for: canal-q5ams2 Candida albicans SC5314 hypothetical protein
Relationship
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Fungi: N E > Dikarya: N E > Ascomycota: N E > saccharomyceta: N E > Saccharomycotina: N E > Saccharomycetes: N E > Saccharomycetales: N E > Debaryomycetaceae: N E > Candida/Lodderomyces clade: N E > Candida [Debaryomycetaceae]: N E > Candida albicans: N E > Candida albicans SC5314: N E 6_AlphaBeta_hydrolase :
canal-q5ams7 Candida albicans SC5314 hypothetical protein ,
canal-q59k70 Candida albicans SC5314 hypothetical protein ,
canal-q59s22 Candida albicans SC5314 potential vacuolar protein ,
canal-q59vf1 Candida albicans SC5314 potential esterase/lipase/thioesterase/phosphatase .
A85-EsteraseD-FGH :
canal-q59nl9 Candida albicans SC5314 hypothetical protein .
ABHD11-Acetyl_transferase :
canal-q5a0i7 Candida albicans SC5314 hypothetical protein ,
canal-q59we9 Candida albicans SC5314 hypothetical protein .
ABHD13-BEM46 :
canal-q5acl5 Candida albicans SC5314 hypothetical protein .
abh_upf0017 :
canal-q59u61 Candida albicans (strains WO-1; SC5314) (Yeast) hypothetical protein .
Acidic_Lipase :
canal-q5ad17 Candida albicans, Candida tropicalis, Candida dubliniensis (Yeast) hypothetical protein tgl1 ,
canal-q5akz5 Candida albicans, Candida dubliniensis (Yeast) hypothetical protein tgl99 .
Carboxypeptidase_S10 :
canal-q5aa97 Candida albicans PRC3 CPY2 potential serine carboxypeptidase ,
canal-q59nw6 Candida albicans (Yeast), Candida dubliniensis, potential serine carboxypeptidase .
CGI-58_ABHD5_ABHD4 :
canal-q59ng0 Candida albicans SC5314 cardiolipin-specific phospholipase ,
canal-q59y42 Candida albicans SC5314 hypothetical protein ,
canal-q59y97 Candida albicans (strains SC5314; WO-1) (Yeast)hypothetical protein .
Dienelactone_hydrolase :
canal-q5ai87 Candida albicans SC5314 hypothetical protein ,
canal-q5amn4 Candida albicans SC5314 hypothetical protein ,
canal-q5amn7 Candida albicans SC5314 hypothetical protein .
DPP4N_Peptidase_S9 :
canal-q5ag57 Candida albicans, Candida dubliniensis, hypothetical protein dap2 ,
canal-q59m48 Candida albicans, Candida dubliniensis, potential alpha-factor pheromone maturation protease .
Duf_676 :
canal-q5ak29 Candida albicans SC5314 hypothetical protein ,
canal-q59kl3 Candida albicans potential lipid particle serine esterase ,
canal-q59ln6 Candida albicans SC5314 hypothetical protein .
FSH1 :
canal-q5adx4 Candida albicans; Candida dubliniensis hypothetical protein ,
canal-q5akr2 Candida albicans; Candida dubliniensis hypothetical protein .
Fusarinine_C_esterase_sidJ :
canal-q5ajt3 Candida albicans (Yeast). hypothetical protein .
Homoserine_transacetylase :
canal-q5a948 Candida albicans SC5314 potential homoserine o-trans-acetylase ,
canal-q59tt5 Candida albicans SC5314 potential serine o-trans-acetylase .
Lipase_3 :
canal-q5amg8 Candida albicans SC5314 potential triglyceride lipase ,
canal-q59xq6 Candida albicans SC5314 potential secreted triacylglycerol lipase. Autophagy-related protein 15 .
LYsophospholipase_carboxylesterase :
canal-apth1 Candida albicans SC5314 likely phospholipase/carboxylesterase .
Monoglyceridelipase_lysophospholip :
canal-q5apu4 Candida albicans, Candida dubliniensis hypothetical protein yju3 .
Palmitoyl-protein_thioesterase :
canal-q5a6l4 Candida albicans SC5314 hypothetical protein ppt2 .
PC-sterol_acyltransferase :
canal-q5abf2 Candida albicans SC5314 hypothetical protein lro1 .
PGAP1 :
canal-q5ai09 Candida albicans (strains SC5314; WO-1) hypothetical protein tgl2 ,
canal-q59vp0 Candida albicans (strains SC5314; WO-1) hypothetical protein bst1 .
PPase_methylesterase_euk :
canal-ppme1 Candida albicans (and strain WO-1)Candida dubliniensis (strain CD36 / CBS 7987 / NCPF 3949 / NRR Y-17841) protein phosphatase methylesterase 1 (EC 3.1.1.-) (pme-1) .
Proline_iminopeptidase :
canal-q5a2i9 Candida albicans (Yeast) hypothetical protein pna1 Molecular evidence
Database
No mutation No structure No kinetic No Substrate No inhibitor
Sequence
Graphical view for this peptide sequence: canal-q5ams2 Colored MSA for Duf_676 (raw)
MSDINKSLSSNSKSKSTHLFVLIHGLWGTSSHMATIEKFIKENLPSSTDD
KIATIKPACFRFWKTYDGLELNAKKIIADIFYEIESLKQNNDLEVTKISI
IGYSLGGLISRYVIGLLNELDFFEKIEPIFFSTFATPHVGIQFFNDNIFD
AVANRLGPYLFGKSGGQLFIADHDKILVKMADPQEKYMRGLKKFQKHILL
ANIKNDRTVAFFTSFITDVSPFEELDNIKIVYLDNLPQAKIANKLVRPKF
VDLTKSHRLSLKDKKIFLGNQQEETPFIRKNRWAKILVIALLACLVVPFW
VPFVLISSTTVSIYSFIKIKFVKGPLSPQHWSRVKKFVYGNAPIDPDDAK
VGNVQRLKRRTLDRHESFKGDTSYLTEDTMDRVLYAEERYLNKSRKAGSI
KNEDDEDALVAENTDYNTDSDGVDESSEADTLKSNFKSIEMDIEQNDKVI
SESIETLKSYESFPLFQDHKYKLPLNEDKSFIVKNLNTLDWIKIPVFLDV
WNAHDGIVSRRGAKTNPKGASTIGLWVSILRNHLQENGRADASVNGNQES
TIAHTS
Legend
This sequence has been compared to family alignement (MSA) red => minority aminoacid blue => majority aminoacid color intensity => conservation rate title => sequence position(MSA position)aminoacid rate Catalytic site Catalytic site in the MSA
M S D I N K S L S S N S K S K S T H L F V L I H G L W G T S S H M A T I E K F I K E N L P S S T D D K I A T I K P A C F R F W K T Y D G L E L N A K K I I A D I F Y E I E S L K Q N N D L E V T K I S I I G Y S L G G L I S R Y V I G L L N E L D F F E K I E P I F F S T F A T P H V G I Q F F N D N I F D A V A N R L G P Y L F G K S G G Q L F I A D H D K I L V K M A D P Q E K Y M R G L K K F Q K H I L L A N I K N D R T V A F F T S F I T D V S P F E E L D N I K I V Y L D N L P Q A K I A N K L V R P K F V D L T K S H R L S L K D K K I F L G N Q Q E E T P F I R K N R W A K I L V I A L L A C L V V P F W V P F V L I S S T T V S I Y S F I K I K F V K G P L S P Q H W S R V K K F V Y G N A P I D P D D A K V G N V Q R L K R R T L D R H E S F K G D T S Y L T E D T M D R V L Y A E E R Y L N K S R K A G S I K N E D D E D A L V A E N T D Y N T D S D G V D E S S E A D T L K S N F K S I E M D I E Q N D K V I S E S I E T L K S Y E S F P L F Q D H K Y K L P L N E D K S F I V K N L N T L D W I K I P V F L D V W N A H D G I V S R R G A K T N P K G A S T I G L W V S I L R N H L Q E N G R A D A S V N G N Q E S T I A H T S
Reference
Title: The diploid genome sequence of Candida albicansJones T , Federspiel NA , Chibana H , Dungan J , Kalman S , Magee BB , Newport G , Thorstenson YR , Agabian N and Scherer S <2 more author(s)> Jones T , Federspiel NA , Chibana H , Dungan J , Kalman S , Magee BB , Newport G , Thorstenson YR , Agabian N , Magee PT , Davis RW , Scherer S (- 2) Ref: Proc Natl Acad Sci U S A, 101 :7329, 2004 : PubMed Abstract ESTHER: Jones_2004_Proc.Natl.Acad.Sci.U.S.A_101_7329 PubMedSearch: Jones 2004 Proc.Natl.Acad.Sci.U.S.A 101 7329 PubMedID: 15123810 Gene_locus related to this paper: canal-apth1 ,
canal-ATG15 ,
canal-bna7 ,
canal-c4yl13 ,
canal-cbpy ,
canal-LIP1 ,
canal-LIP2 ,
canal-LIP3 ,
canal-LIP4 ,
canal-LIP5 ,
canal-LIP6 ,
canal-LIP7 ,
canal-LIP8 ,
canal-LIP9 ,
canal-LIP10 ,
canal-ppme1 ,
canal-q5a0c9 ,
canal-q5a0i7 ,
canal-q5a2i9 ,
canal-q5a2u7 ,
canal-q5a6l4 ,
canal-q5a042 ,
canal-q5a948 ,
canal-q5aa97 ,
canal-q5abf2 ,
canal-q5acl5 ,
canal-q5ad17 ,
canal-q5adx4 ,
canal-q5ady2 ,
canal-q5aeu3 ,
canal-q5afp8 ,
canal-q5ag57 ,
canal-q5ah37 ,
canal-q5ai09 ,
canal-q5ai12 ,
canal-q5ai87 ,
canal-q5ajt3 ,
canal-q5ak09 ,
canal-q5ak29 ,
canal-q5ak96 ,
canal-q5akr2 ,
canal-q5akz5 ,
canal-q5amg8 ,
canal-q5amn4 ,
canal-q5amn7 ,
canal-q5ams2 ,
canal-q5ams7 ,
canal-q5apu4 ,
canal-q59k70 ,
canal-q59kl3 ,
canal-q59l46 ,
canal-q59ln6 ,
canal-q59m48 ,
canal-q59ng0 ,
canal-q59nl9 ,
canal-q59nw6 ,
canal-q59nx4 ,
canal-q59nx8 ,
canal-q59s22 ,
canal-q59tt5 ,
canal-q59u61 ,
canal-q59u64 ,
canal-q59vf1 ,
canal-q59vp0 ,
canal-q59we9 ,
canal-q59xq6 ,
canal-q59y42 ,
canal-q59y97 ,
canaw-c4yrr3 ,
canal-hda1 Abstract
We present the diploid genome sequence of the fungal pathogen Candida albicans. Because C. albicans has no known haploid or homozygous form, sequencing was performed as a whole-genome shotgun of the heterozygous diploid genome in strain SC5314, a clinical isolate that is the parent of strains widely used for molecular analysis. We developed computational methods to assemble a diploid genome sequence in good agreement with available physical mapping data. We provide a whole-genome description of heterozygosity in the organism. Comparative genomic analyses provide important clues about the evolution of the species and its mechanisms of pathogenesis.
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