Gene_Locus Report

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Gene_locus Report for: cavpo-1plip

Cavia porcellus (Guinea pig) mRNA for pancreatic lipase

Relationship
Family|Pancreatic_lipase
Block| L
Position in NCBI Life Tree|Cavia porcellus
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Deuterostomia: N E > Chordata: N E > Craniata: N E > Vertebrata: N E > Gnathostomata: N E > Teleostomi: N E > Euteleostomi: N E > Sarcopterygii: N E > Dipnotetrapodomorpha: N E > Tetrapoda: N E > Amniota: N E > Mammalia: N E > Theria: N E > Eutheria: N E > Boreoeutheria: N E > Euarchontoglires: N E > Glires: N E > Rodentia: N E > Hystricomorpha: N E > Caviidae: N E > Cavia: N E > Cavia porcellus: N E


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
2 Genbank : X77403, AAKN02003098
2 UniProt : P50903, H0VNP7
1 Ncbi-nid : 474916
2 UniProt : P50903, H0VNP7
2 Interpro : P50903, H0VNP7
2 Prodom : P50903, H0VNP7
2 Pfam : P50903, H0VNP7
2 PIRSF : P50903, H0VNP7
2 SUPERFAM : P50903, H0VNP7
Sequence
Graphical view for this peptide sequence: cavpo-1plip
Colored MSA for Pancreatic_lipase (raw)
MLLLWILSLFLETVAGGEVCFDRLGCFSDNKPWAGTSERPRKGLPWDPSA
INVRFLLYTNENPNNYQRITADSSVIRSSDFKTDRKTRFIIHGFIDKGEE
NWLADLCKALFQVESVNCICVDWRGGSRTLYSQASQNIQVVGAEVAYLIN
FLQSQLDYPPSSVHIIGHSLGSHAAGEAGRRTNGAIGRITGLDPAEPYFQ
YTPEIVRLDPSDAQFVDVIHTDGNPIIPNLGFGMSQTVGHLDFFPNGGLQ
MPGCQKNILSQIVDIDGIWEGTRDFAACNHLRSYKYYIDSITNPKGFAGF
SCDSYSSFSSNKCFPCATGECPQMGHYADKFPGKTKENFQNFYLNTGDKS
NFSRWRYRIAVTLSGQKVTGHVLVSLFGDAGNTKQYEIYRGSLKPGNNHS
NEIDSDVDVGDLQKVKFIWYNNVINITLPKVGASRITVTRSDGRVFDFCS
QDTVREEVLLTLQPC
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MLLLWILSLFLETVAGGEVCFDRLGCFSDNKPWAGTSERPRKGLPWDPSA
INVRFLLYTNENPNNYQRITADSSVIRSSDFKTDRKTRFIIHGFIDKGEE
NWLADLCKALFQVESVNCICVDWRGGSRTLYSQASQNIQVVGAEVAYLIN
FLQSQLDYPPSSVHIIGHSLGSHAAGEAGRRTNGAIGRITGLDPAEPYFQ
YTPEIVRLDPSDAQFVDVIHTDGNPIIPNLGFGMSQTVGHLDFFPNGGLQ
MPGCQKNILSQIVDIDGIWEGTRDFAACNHLRSYKYYIDSITNPKGFAGF
SCDSYSSFSSNKCFPCATGECPQMGHYADKFPGKTKENFQNFYLNTGDKS
NFSRWRYRIAVTLSGQKVTGHVLVSLFGDAGNTKQYEIYRGSLKPGNNHS
NEIDSDVDVGDLQKVKFIWYNNVINITLPKVGASRITVTRSDGRVFDFCS
QDTVREEVLLTLQPC


References
    Title: A high-resolution map of human evolutionary constraint using 29 mammals
    Lindblad-Toh K, Garber M, Zuk O, Lin MF, Parker BJ, Washietl S, Kheradpour P, Ernst J, Jordan G and Kellis M <76 more author(s)>
    Ref: Nature, 478:476, 2011 : PubMed

            

    Title: Cloning of the classical guinea pig pancreatic lipase and comparison with the lipase related protein 2
    Carriere F, Thirstrup K, Hjorth S, Boel E
    Ref: FEBS Letters, 338:63, 1994 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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