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Gene_locus Report for: cavpo-h0v8y6

Cavia porcellus (Guinea pig). Abhydrolase domain containing 8

Relationship
Family|ABHD8
Block| X
Position in NCBI Life Tree|Cavia porcellus
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Deuterostomia: N E > Chordata: N E > Craniata: N E > Vertebrata: N E > Gnathostomata: N E > Teleostomi: N E > Euteleostomi: N E > Sarcopterygii: N E > Dipnotetrapodomorpha: N E > Tetrapoda: N E > Amniota: N E > Mammalia: N E > Theria: N E > Eutheria: N E > Boreoeutheria: N E > Euarchontoglires: N E > Glires: N E > Rodentia: N E > Hystricomorpha: N E > Caviidae: N E > Cavia: N E > Cavia porcellus: N E


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
2 Genbank : AAKN02049177, XP_005001226
2 UniProt : H0V8Y6, A0A286Y1N1
2 UniProt : H0V8Y6, A0A286Y1N1
2 Interpro : H0V8Y6, A0A286Y1N1
2 Prodom : H0V8Y6, A0A286Y1N1
2 Pfam : H0V8Y6, A0A286Y1N1
2 PIRSF : H0V8Y6, A0A286Y1N1
2 SUPERFAM : H0V8Y6, A0A286Y1N1
Sequence
Graphical view for this peptide sequence: cavpo-h0v8y6
Colored MSA for ABHD8 (raw)
MLTGVTEGFLCCLLGSTPNAVGPLESVESGDGYTFVEVKPGRVLRVKHAG
PAPAPSPPPPPETVQGNRAGLVRCQRRITVYRNGRLLVENLGRAPRADLG
HGQGDCEPPAALEVELAEPAGAEGRAHAGGSGSGRRRRARRPKRTIHIDC
EKRITSCKGAQADVVLFFIHGVGGSLAIWKEQLDFFVRLGYEVVAPDLAG
HGASSAPQVAAAYTFYALAEDMRAIFKRYAKKRNVLIGHSYGVSFCTFLA
HEYPDLVHKVIMINGGGPTALEPSICSIFNMPACVLHCLSPCLAWSFLKA
GFAHQGAKEKQLLKEGNAFNVSSFVLRAMMSGQYWPEGDEVYHAELTVPV
LLVHGMHDKFVPVEEDQRMAEILLLAFLKLIDEGSHMVMLECPETVNTLL
HEFLLWEPEPLPRALPDPQPALLRGQQC
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MLTGVTEGFLCCLLGSTPNAVGPLESVESGDGYTFVEVKPGRVLRVKHAG
PAPAPSPPPPPETVQGNRAGLVRCQRRITVYRNGRLLVENLGRAPRADLG
HGQGDCEPPAALEVELAEPAGAEGRAHAGGSGSGRRRRARRPKRTIHIDC
EKRITSCKGAQADVVLFFIHGVGGSLAIWKEQLDFFVRLGYEVVAPDLAG
HGASSAPQVAAAYTFYALAEDMRAIFKRYAKKRNVLIGHSYGVSFCTFLA
HEYPDLVHKVIMINGGGPTALEPSICSIFNMPACVLHCLSPCLAWSFLKA
GFAHQGAKEKQLLKEGNAFNVSSFVLRAMMSGQYWPEGDEVYHAELTVPV
LLVHGMHDKFVPVEEDQRMAEILLLAFLKLIDEGSHMVMLECPETVNTLL
HEFLLWEPEPLPRALPDPQPALLRGQQC


Reference
    Title: A high-resolution map of human evolutionary constraint using 29 mammals
    Lindblad-Toh K, Garber M, Zuk O, Lin MF, Parker BJ, Washietl S, Kheradpour P, Ernst J, Jordan G and Kellis M <76 more author(s)>
    Ref: Nature, 478:476, 2011 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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