Gene_Locus Report

Biblio print

Add to basket

Go to basket

Tree Display

AceDB Schema

XML Display

Feedback

Gene_locus Report for: cavpo-pafa

Cavia porcellus (Guinea pig) plasma Paf-acetylhydrolase

Relationship
Family|PAF-Acetylhydrolase
Block| X
Position in NCBI Life Tree|Cavia porcellus
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Deuterostomia: N E > Chordata: N E > Craniata: N E > Vertebrata: N E > Gnathostomata: N E > Teleostomi: N E > Euteleostomi: N E > Sarcopterygii: N E > Dipnotetrapodomorpha: N E > Tetrapoda: N E > Amniota: N E > Mammalia: N E > Theria: N E > Eutheria: N E > Boreoeutheria: N E > Euarchontoglires: N E > Glires: N E > Rodentia: N E > Hystricomorpha: N E > Caviidae: N E > Cavia: N E > Cavia porcellus: N E


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
1 Genbank : D67037
1 UniProt : P70683
1 Ncbi-nid : 1644228
2 Ncbi-pid : 1644229, 2497686
1 UniProt : P70683
1 Interpro : P70683
1 Prodom : P70683
1 Pfam : P70683
1 PIRSF : P70683
1 SUPERFAM : P70683
Sequence
Graphical view for this peptide sequence: cavpo-pafa
Colored MSA for PAF-Acetylhydrolase (raw)
MAPPKLHTLFCLSGFLALVHPFDWRDLDPVTYIQSSVWIQRIQSELLITS
FGHTTIPKGNGPYSVGCTDLMSGYTNQSSFLRLYYPSQDNDFPDALWIPN
EEYFQGLTETLGASSFLGKLLKLLYGSVKVPAKWNSPLKTGEKYPLIIFS
HGLGAFRSIYSAIGIELASHGFIVAAVEHRDESAAATYYFQDAPAAESGN
RSWIYYKVGNLETEERKRQLRQRGEECSQALSWLLSIDEGEPVKNVLDLN
FDIQQLKGSLDRSKVAIIGHSFGGATVIQTLSEDQRFRCGIALDPWMFPV
GEDVHSKIPQPLFFINSEYFQSANDTKKIEKFYQPQKERKMIAVKGSVHH
NFVDFTFATGKIIGQMLSLKGKIDSEVAMDLINKASLAFLQKYLGLDKNF
DQWNSLMEGDDENLIPEFTIPTTMQSSTGTEQRNPD
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MAPPKLHTLFCLSGFLALVHPFDWRDLDPVTYIQSSVWIQRIQSELLITS
FGHTTIPKGNGPYSVGCTDLMSGYTNQSSFLRLYYPSQDNDFPDALWIPN
EEYFQGLTETLGASSFLGKLLKLLYGSVKVPAKWNSPLKTGEKYPLIIFS
HGLGAFRSIYSAIGIELASHGFIVAAVEHRDESAAATYYFQDAPAAESGN
RSWIYYKVGNLETEERKRQLRQRGEECSQALSWLLSIDEGEPVKNVLDLN
FDIQQLKGSLDRSKVAIIGHSFGGATVIQTLSEDQRFRCGIALDPWMFPV
GEDVHSKIPQPLFFINSEYFQSANDTKKIEKFYQPQKERKMIAVKGSVHH
NFVDFTFATGKIIGQMLSLKGKIDSEVAMDLINKASLAFLQKYLGLDKNF
DQWNSLMEGDDENLIPEFTIPTTMQSSTGTEQRNPD


Reference
    Title: Cloning, expression and characterization of plasma platelet-activating factor-acetylhydrolase from guinea pig
    Karasawa K, Kuge O, Kawasaki K, Nishijima M, Nakano Y
    Ref: Journal of Biochemistry, 120:838, 1996 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page
webmaster

Acknowledgements and disclaimer